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Gene: Smad9 (SMAD family member 9) Mus musculus
Symbol: Smad9
Name: SMAD family member 9
Description: This gene encodes a member of a family of proteins that act as downstream effectors of the bone morphogenetic protein (BMP) signaling pathway. The encoded protein is phosphorylated by BMP receptors, which stimulates its binding to SMAD4 and translocation into the nucleus, where it functions as a regulator of transcription. Activity of this protein is important for embryonic development. Mutation of this gene results in defects in pulmonary vasculature. [provided by RefSeq, Mar 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MAD homolog 9; MADH6; Madh8; Madh9; mothers against decapentaplegic homolog 9; mothers against DPP homolog 9; SMAD 9; Smad8; SMAD8A; SMAD8B
Homo sapiens (human) : SMAD9 (SMAD family member 9)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Smad9 (SMAD family member 9)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smad9 (SMAD family member 9)
Pan paniscus (bonobo/pygmy chimpanzee) : SMAD9 (SMAD family member 9)
Canis lupus familiaris (dog) : SMAD9 (SMAD family member 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smad9 (SMAD family member 9)
Sus scrofa (pig) : SMAD9 (SMAD family member 9)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38354,755,455 - 54,801,662 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37354,559,504 - 54,605,179 (+)NCBIGRCm37mm9NCBIm37
MGSCv36354,843,511 - 54,889,186 (+)NCBImm8
Celera354,477,243 - 54,523,163 (+)NCBICelera
Cytogenetic Map3 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Smad9
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733518
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-08-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.