Slc6a6 (solute carrier family 6 (neurotransmitter transporter, taurine), member 6) - Rat Genome Database

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Gene: Slc6a6 (solute carrier family 6 (neurotransmitter transporter, taurine), member 6) Mus musculus
Analyze
Symbol: Slc6a6
Name: solute carrier family 6 (neurotransmitter transporter, taurine), member 6
RGD ID: 62205
MGI Page MGI
Description: Enables beta-alanine transmembrane transporter activity; gamma-aminobutyric acid:sodium:chloride symporter activity; and taurine:sodium symporter activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within beta-alanine transport and taurine transmembrane transport. Is active in GABA-ergic synapse and postsynaptic membrane. Is expressed in several structures, including brain; cardiovascular system; retina; spinal cord mantle layer; and tooth. Used to study retinitis pigmentosa. Orthologous to human SLC6A6 (solute carrier family 6 member 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA589629; C80501; sodium- and chloride-dependent taurine transporter; solute carrier family 6 member 6; Tau; taurine/beta-alanine transporter; Taut
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,661,031 - 91,736,044 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl691,661,034 - 91,736,047 (+)EnsemblGRCm39 Ensembl
GRCm38691,684,048 - 91,759,063 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,684,053 - 91,759,066 (+)EnsemblGRCm38mm10GRCm38
MGSCv37691,634,061 - 91,709,057 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36691,649,599 - 91,724,567 (+)NCBIMGSCv36mm8
Celera693,577,782 - 93,652,873 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-pilocarpine  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1-benzylpiperazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
alpha-Zearalanol  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
avobenzone  (ISO)
azathioprine  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP,ISO)
bromobenzene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chloroacetaldehyde  (ISO)
chloroprene  (ISO)
chlorpromazine  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
clomipramine  (ISO)
cobalt dichloride  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (ISO)
dextran sulfate  (EXP)
diallyl disulfide  (ISO)
diallyl trisulfide  (ISO)
Diallyltetrasulfane  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
fenthion  (EXP)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glycidyl methacrylate  (ISO)
imipramine  (ISO)
indole-3-methanol  (ISO)
ketoconazole  (ISO)
L-ethionine  (ISO)
lead diacetate  (ISO)
lead(II) chloride  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
metformin  (ISO)
methidathion  (EXP)
methimazole  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
omeprazole  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
parathion  (EXP)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
taurine  (EXP)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
topiramate  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
valproic acid  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zearalenone  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. Ubhi K, etal., Eur J Neurosci. 2014 Mar;39(6):1026-41. doi: 10.1111/ejn.12444. Epub 2013 Dec 5.
Additional References at PubMed
PMID:1465453   PMID:7774940   PMID:8641130   PMID:8649829   PMID:8889548   PMID:9375654   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11772953  
PMID:11908948   PMID:12466851   PMID:12477932   PMID:12520002   PMID:12824447   PMID:12904583   PMID:14610273   PMID:14631140   PMID:14681479   PMID:14734644   PMID:15149840   PMID:15226823  
PMID:15489334   PMID:15606752   PMID:15630240   PMID:15782199   PMID:15914036   PMID:16125675   PMID:16141072   PMID:16141073   PMID:16249932   PMID:16421246   PMID:16550472   PMID:16602821  
PMID:17081118   PMID:17153590   PMID:17153611   PMID:17459327   PMID:17540781   PMID:17785795   PMID:17962336   PMID:17967808   PMID:18407290   PMID:18799693   PMID:19423693   PMID:20100858  
PMID:20804603   PMID:21160187   PMID:21267068   PMID:21873635   PMID:22383044   PMID:22531910   PMID:23381576   PMID:24321512   PMID:24734001   PMID:25229346   PMID:25437920   PMID:25629817  
PMID:27444300   PMID:28559309   PMID:28572444   PMID:29491220   PMID:30270321   PMID:30862735   PMID:31961823   PMID:32290105   PMID:32554809   PMID:32705197   PMID:32968166   PMID:33500475  
PMID:34321999   PMID:35882796   PMID:36293380   PMID:36466806   PMID:36604605   PMID:37289866   PMID:37561545   PMID:37816598   PMID:38355793  


Genomics

Comparative Map Data
Slc6a6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,661,031 - 91,736,044 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl691,661,034 - 91,736,047 (+)EnsemblGRCm39 Ensembl
GRCm38691,684,048 - 91,759,063 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,684,053 - 91,759,066 (+)EnsemblGRCm38mm10GRCm38
MGSCv37691,634,061 - 91,709,057 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36691,649,599 - 91,724,567 (+)NCBIMGSCv36mm8
Celera693,577,782 - 93,652,873 (+)NCBICelera
Cytogenetic Map6D1NCBI
cM Map640.73NCBI
SLC6A6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38314,402,576 - 14,489,349 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl314,402,576 - 14,489,349 (+)EnsemblGRCh38hg38GRCh38
GRCh37314,444,076 - 14,530,857 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36314,419,110 - 14,505,861 (+)NCBINCBI36Build 36hg18NCBI36
Build 34314,419,109 - 14,503,973NCBI
Celera314,382,349 - 14,469,089 (+)NCBICelera
Cytogenetic Map3p25.1ENTREZGENE
HuRef314,380,198 - 14,466,798 (+)NCBIHuRef
CHM1_1314,395,197 - 14,481,943 (+)NCBICHM1_1
T2T-CHM13v2.0314,405,068 - 14,491,755 (+)NCBIT2T-CHM13v2.0
Slc6a6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84125,752,340 - 125,826,033 (+)NCBIGRCr8
mRatBN7.24124,195,186 - 124,268,880 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4124,195,218 - 124,268,875 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4129,662,156 - 129,732,221 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04125,436,590 - 125,506,651 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04124,061,127 - 124,131,197 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04123,638,619 - 123,713,469 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4123,642,210 - 123,713,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04188,172,660 - 188,246,142 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44125,875,817 - 125,945,795 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14126,120,297 - 126,190,631 (+)NCBI
Celera4113,114,633 - 113,184,598 (+)NCBICelera
Cytogenetic Map4q34NCBI
Slc6a6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,098,268 - 17,130,433 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,097,753 - 17,130,079 (+)NCBIChiLan1.0ChiLan1.0
SLC6A6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2214,383,728 - 14,471,476 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1314,384,213 - 14,476,238 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0314,323,251 - 14,411,949 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1314,663,949 - 14,752,326 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl314,663,955 - 14,752,326 (+)Ensemblpanpan1.1panPan2
SLC6A6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1204,544,739 - 4,616,797 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl204,531,771 - 4,620,605 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha204,569,550 - 4,653,981 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0204,553,241 - 4,637,965 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl204,553,024 - 4,638,198 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1204,272,086 - 4,356,526 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0204,594,760 - 4,679,179 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0204,605,361 - 4,690,391 (+)NCBIUU_Cfam_GSD_1.0
Slc6a6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494218,633,842 - 18,667,901 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936602233,753 - 274,982 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC6A6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1370,094,079 - 70,173,582 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11370,094,073 - 70,173,581 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21377,572,736 - 77,608,407 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC6A6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12250,344,781 - 50,431,765 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2250,344,805 - 50,431,766 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041116,063,292 - 116,150,295 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc6a6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248721,266,007 - 1,310,361 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248721,266,240 - 1,318,710 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc6a6
1784 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1854
Count of miRNA genes:718
Interacting mature miRNAs:958
Transcripts:ENSMUST00000032185
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671958006105958152Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671958006105958152Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67797698396976961Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67552133992584431Mouse
12792979Fbmd2_mfemoral bone mineral density 2, females only (mouse)675026989115026943Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67552133994202936Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671552042105552160Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67129960593441074Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675424566104480516Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined688982366122982564Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687480321121480516Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684099474118099474Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686783787113521563Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675584287109584431Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670402880104403016Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676440930110441074Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670402880104403016Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675693484109693678Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690772571124772807Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666690851100691013Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670402880104403016Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681476981102176961Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673476983134676963Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67552133994202936Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678606487121092347Mouse

Markers in Region
AA589629  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38691,755,592 - 91,755,688UniSTSGRCm38
MGSCv37691,705,586 - 91,705,682UniSTSGRCm37
Celera693,649,400 - 93,649,496UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.2UniSTS
Whitehead/MRC_RH6933.31UniSTS
C80501  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38691,758,389 - 91,758,481UniSTSGRCm38
MGSCv37691,708,383 - 91,708,475UniSTSGRCm37
Celera693,652,197 - 93,652,289UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.2UniSTS
Whitehead/MRC_RH6933.01UniSTS
RH125023  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38691,755,520 - 91,755,697UniSTSGRCm38
MGSCv37691,705,514 - 91,705,691UniSTSGRCm37
Celera693,649,328 - 93,649,505UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.2UniSTS
AW531182  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38691,710,959 - 91,711,140UniSTSGRCm38
MGSCv37691,660,953 - 91,661,134UniSTSGRCm37
Celera693,604,620 - 93,604,801UniSTS
Cytogenetic Map6D1UniSTS
cM Map638.2UniSTS
Slc6a6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
cM Map638.2UniSTS
Slc6a6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001410446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_177073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006505870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003956177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC118245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK041141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB636410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ059053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L03292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000032185   ⟹   ENSMUSP00000032185
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,661,034 - 91,736,047 (+)Ensembl
GRCm38.p6 Ensembl691,684,053 - 91,759,066 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205443
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,661,050 - 91,712,161 (+)Ensembl
GRCm38.p6 Ensembl691,684,069 - 91,735,180 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205477
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,725,337 - 91,727,151 (+)Ensembl
GRCm38.p6 Ensembl691,748,356 - 91,750,170 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205480   ⟹   ENSMUSP00000145794
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,661,101 - 91,701,923 (+)Ensembl
GRCm38.p6 Ensembl691,684,120 - 91,724,942 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205663   ⟹   ENSMUSP00000145986
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,701,940 - 91,722,010 (+)Ensembl
GRCm38.p6 Ensembl691,724,959 - 91,745,029 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205764
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,716,630 - 91,718,076 (+)Ensembl
GRCm38.p6 Ensembl691,739,649 - 91,741,095 (+)Ensembl
Ensembl Acc Id: ENSMUST00000205828   ⟹   ENSMUSP00000146312
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,678,638 - 91,701,844 (+)Ensembl
GRCm38.p6 Ensembl691,701,657 - 91,724,863 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206451
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,661,130 - 91,676,290 (+)Ensembl
GRCm38.p6 Ensembl691,684,149 - 91,699,309 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206545   ⟹   ENSMUSP00000146306
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,661,109 - 91,701,958 (+)Ensembl
GRCm38.p6 Ensembl691,684,128 - 91,724,977 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206835
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,661,076 - 91,703,912 (+)Ensembl
GRCm38.p6 Ensembl691,684,095 - 91,726,931 (+)Ensembl
Ensembl Acc Id: ENSMUST00000206988
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl691,727,165 - 91,729,759 (+)Ensembl
GRCm38.p6 Ensembl691,750,184 - 91,752,778 (+)Ensembl
RefSeq Acc Id: NM_001410446   ⟹   NP_001397375
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: NM_001410447   ⟹   NP_001397376
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: NM_001410448   ⟹   NP_001397377
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: NM_001410449   ⟹   NP_001397378
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: NM_001410450   ⟹   NP_001397379
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: NM_001410451   ⟹   NP_001397380
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,703,913 (+)NCBI
RefSeq Acc Id: NM_001410452   ⟹   NP_001397381
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,682,855 - 91,703,913 (+)NCBI
RefSeq Acc Id: NM_009320   ⟹   NP_033346
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
GRCm38691,684,067 - 91,759,063 (+)NCBI
MGSCv37691,634,061 - 91,709,057 (+)RGD
Celera693,577,782 - 93,652,873 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_177072
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: NR_177073
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,085 - 91,736,044 (+)NCBI
RefSeq Acc Id: XM_006505870   ⟹   XP_006505933
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,686,505 - 91,736,041 (+)NCBI
GRCm38691,709,524 - 91,759,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255304   ⟹   XP_030111164
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,682,860 - 91,736,041 (+)NCBI
GRCm38691,705,879 - 91,759,063 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036166008   ⟹   XP_036021901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,668,852 - 91,736,041 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036166010   ⟹   XP_036021903
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,698,712 - 91,736,041 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003956177
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,661,031 - 91,736,044 (+)NCBI
GRCm38691,684,048 - 91,759,063 (+)NCBI
Sequence:
RefSeq Acc Id: NP_033346   ⟸   NM_009320
- Peptide Label: isoform a
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006505933   ⟸   XM_006505870
- Peptide Label: isoform X2
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111164   ⟸   XM_030255304
- Peptide Label: isoform X2
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000032185   ⟸   ENSMUST00000032185
Ensembl Acc Id: ENSMUSP00000146306   ⟸   ENSMUST00000206545
Ensembl Acc Id: ENSMUSP00000146312   ⟸   ENSMUST00000205828
Ensembl Acc Id: ENSMUSP00000145794   ⟸   ENSMUST00000205480
Ensembl Acc Id: ENSMUSP00000145986   ⟸   ENSMUST00000205663
RefSeq Acc Id: XP_036021901   ⟸   XM_036166008
- Peptide Label: isoform X2
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_036021903   ⟸   XM_036166010
- Peptide Label: isoform X2
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397376   ⟸   NM_001410447
- Peptide Label: isoform a
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397377   ⟸   NM_001410448
- Peptide Label: isoform b
RefSeq Acc Id: NP_001397378   ⟸   NM_001410449
- Peptide Label: isoform c precursor
RefSeq Acc Id: NP_001397375   ⟸   NM_001410446
- Peptide Label: isoform a
- UniProtKB: P31642 (UniProtKB/Swiss-Prot),   O35316 (UniProtKB/Swiss-Prot),   Q91WI2 (UniProtKB/Swiss-Prot),   Q3UPI8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397379   ⟸   NM_001410450
- Peptide Label: isoform d precursor
RefSeq Acc Id: NP_001397380   ⟸   NM_001410451
- Peptide Label: isoform e
- UniProtKB: Q8BRX2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397381   ⟸   NM_001410452
- Peptide Label: isoform e
- UniProtKB: Q8BRX2 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35316-F1-model_v2 AlphaFold O35316 1-621 view protein structure

Promoters
RGD ID:6840004
Promoter ID:MM_KWN:46927
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_009320_SLC6A6,   UC009CYG.1,   UC009CYH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36691,633,241 - 91,634,532 (+)MPROMDB
RGD ID:6890456
Promoter ID:EPDNEW_M8679
Type:initiation region
Name:Slc6a6_1
Description:Mus musculus solute carrier family 6 (neurotransmitter transporter,taurine), member 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8680  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38691,684,104 - 91,684,164EPDNEW
RGD ID:6890458
Promoter ID:EPDNEW_M8680
Type:multiple initiation site
Name:Slc6a6_2
Description:Mus musculus solute carrier family 6 (neurotransmitter transporter,taurine), member 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M8679  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38691,705,874 - 91,705,934EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98488 AgrOrtholog
Ensembl Genes ENSMUSG00000030096 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032185 ENTREZGENE
  ENSMUST00000032185.9 UniProtKB/Swiss-Prot
  ENSMUST00000205480.2 UniProtKB/TrEMBL
  ENSMUST00000205663.2 UniProtKB/TrEMBL
  ENSMUST00000205828.2 UniProtKB/TrEMBL
  ENSMUST00000206545.2 UniProtKB/TrEMBL
  ENSMUST00000206835 ENTREZGENE
InterPro Na/ntran_symport UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Na/ntran_symport_taurine UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SNS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21366 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98488 ENTREZGENE
NCBI Gene 21366 ENTREZGENE
PANTHER PTHR11616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SODIUM- AND CHLORIDE-DEPENDENT TAURINE TRANSPORTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slc6a6 PhenoGen
PRINTS NANEUSMPORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TAUTRANSPORT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NA_NEUROTRAN_SYMP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NA_NEUROTRAN_SYMP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF161070 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0U1RP20_MOUSE UniProtKB/TrEMBL
  A0A0U1RPH7_MOUSE UniProtKB/TrEMBL
  A0A0U1RQA0_MOUSE UniProtKB/TrEMBL
  A0A0U1RQA5_MOUSE UniProtKB/TrEMBL
  O35316 ENTREZGENE
  P31642 ENTREZGENE
  Q3UPI8 ENTREZGENE, UniProtKB/TrEMBL
  Q8BRX2 ENTREZGENE, UniProtKB/TrEMBL
  Q91WI2 ENTREZGENE
  SC6A6_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary P31642 UniProtKB/Swiss-Prot
  Q91WI2 UniProtKB/Swiss-Prot