Igfbp1 (insulin-like growth factor binding protein 1) - Rat Genome Database

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Gene: Igfbp1 (insulin-like growth factor binding protein 1) Mus musculus
Analyze
Symbol: Igfbp1
Name: insulin-like growth factor binding protein 1
RGD ID: 69039
MGI Page MGI
Description: Enables insulin-like growth factor binding activity. Acts upstream of or within response to insulin. Located in extracellular space. Is expressed in several structures, including early embryo; jaw; liver; mandible primordium; and secondary oocyte. Human ortholog(s) of this gene implicated in diabetic angiopathy. Orthologous to human IGFBP1 (insulin like growth factor binding protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: IBP-1; IGF-binding protein 1; IGFBP; insulin-like growth factor binding protein 1 precursor (IGFBP-1) (IBP-1) (IGF-binding protein 1); insulin-like growth factor-binding protein 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,147,787 - 7,152,546 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl117,147,782 - 7,152,546 (+)EnsemblGRCm39 Ensembl
GRCm38117,197,787 - 7,202,546 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,197,782 - 7,202,546 (+)EnsemblGRCm38mm10GRCm38
MGSCv37117,097,790 - 7,102,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36117,097,785 - 7,102,539 (+)NCBIMGSCv36mm8
Celera117,672,987 - 7,677,746 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (EXP)
1-methylphenanthrene  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2'-bipyridine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
2-butoxyethanol  (EXP)
2-hydroxy-17beta-estradiol  (ISO)
2-nitrofluorene  (ISO)
28-Homobrassinolide  (ISO)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO)
4-hydroxy-17beta-estradiol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (ISO)
8-Br-cAMP  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
Archazolid B  (ISO)
aristolochic acids  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atazanavir sulfate  (ISO)
azoxystrobin  (ISO)
bacitracin  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bicalutamide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bucladesine  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
chenodeoxycholic acid  (EXP,ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
choline  (EXP)
chromium(3+) trichloride  (EXP)
ciguatoxin CTX1B  (EXP)
ciprofibrate  (EXP)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clotrimazole  (ISO)
clozapine  (ISO)
cobalt dichloride  (EXP)
colforsin daropate hydrochloride  (ISO)
copper(II) sulfate  (ISO)
corn oil  (ISO)
cortisol  (ISO)
curcumin  (ISO)
cyanamide  (ISO)
cyclosporin A  (ISO)
cypermethrin  (EXP)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenz[a,h]anthracene  (EXP,ISO)
dibenzo[a,l]pyrene  (ISO)
dichloroacetic acid  (EXP)
diclofenac  (EXP,ISO)
diethylstilbestrol  (EXP,ISO)
dimethylarsinic acid  (EXP)
dioxygen  (ISO)
doxorubicin  (EXP,ISO)
enalapril  (ISO)
epoxiconazole  (EXP)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
fentin chloride  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
fumonisin B1  (EXP)
furan  (EXP,ISO)
genistein  (ISO)
gentamycin  (ISO)
glycidol  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
glyphosate  (ISO)
GW 4064  (EXP)
hydrogen peroxide  (ISO)
imidacloprid  (ISO)
indirubin  (ISO)
indole-3-methanol  (ISO)
inulin  (EXP)
ketamine  (ISO)
ketoconazole  (ISO)
kynurenine  (ISO)
L-methionine  (EXP)
L-tryptophan  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (EXP,ISO)
lisinopril dihydrate  (ISO)
medroxyprogesterone acetate  (ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (EXP)
methylmercury(1+)  (ISO)
metyrapone  (ISO)
microcystin-LR  (EXP)
mifepristone  (ISO)
N-acetyl-L-cysteine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nicotinamide  (EXP)
nitrofen  (ISO)
ochratoxin A  (ISO)
orphenadrine  (ISO)
oxazepam  (EXP)
oxycodone  (ISO)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phorone  (ISO)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
potassium bromate  (ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
quinolin-8-ol  (ISO)
resveratrol  (EXP,ISO)
riddelliine  (ISO)
rifampicin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
silicon dioxide  (ISO)
sirolimus  (ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sotorasib  (ISO)
starch  (ISO)
stavudine  (ISO)
succimer  (ISO)
Sunset Yellow FCF  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (EXP,ISO)
tauroursodeoxycholic acid  (ISO)
testosterone  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thiabendazole  (ISO)
thioacetamide  (ISO)
tianeptine  (ISO)
titanium dioxide  (EXP)
tolcapone  (ISO)
trametinib  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP)
triclosan  (ISO)
Triptolide  (EXP,ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP)
vancomycin  (EXP,ISO)
vandetanib  (ISO)
vemurafenib  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Roles of insulin-like growth factor (IGF) binding proteins in regulating IGF actions. Duan C and Xu Q, Gen Comp Endocrinol. 2005 May 15;142(1-2):44-52. Epub 2005 Feb 5.
2. Serum IGF-binding protein-6 and prostate specific antigen in breast cancer. Kaulsay KK, etal., Eur J Endocrinol. 1999 Feb;140(2):164-8.
3. Mosaic analysis of insulin receptor function. Kitamura T, etal., J Clin Invest 2004 Jan;113(2):209-19.
4. Regulation of the acid-labile subunit in sustained endotoxemia. Kong SE, etal., Am J Physiol Endocrinol Metab 2002 Oct;283(4):E692-701.
5. Acute response of IGF-I and IGF binding proteins induced by thermal injury. Lang CH, etal., Am J Physiol Endocrinol Metab. 2000 Jun;278(6):E1087-96.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. Growth hormone-binding protein is directly and IGFBP-3 is inversely associated with risk of female breast cancer. Pazaitou-Panayiotou K, etal., Eur J Endocrinol. 2007 Feb;156(2):187-94.
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Polymorphisms in IGF-binding protein 1 are associated with impaired renal function in type 2 diabetes. Stephens RH, etal., Diabetes. 2005 Dec;54(12):3547-53.
Additional References at PubMed
PMID:1284245   PMID:1419914   PMID:2062642   PMID:2355916   PMID:7505465   PMID:7509771   PMID:7510770   PMID:7511095   PMID:7525452   PMID:7529732   PMID:7640658   PMID:7679139  
PMID:7684980   PMID:7750499   PMID:8923818   PMID:8928760   PMID:8932988   PMID:9002662   PMID:9014844   PMID:9093203   PMID:9175833   PMID:9184077   PMID:9324049   PMID:9662407  
PMID:9685224   PMID:9785199   PMID:10226804   PMID:10502456   PMID:10579362   PMID:10645956   PMID:10744620   PMID:10888943   PMID:10976924   PMID:11033447   PMID:12163409   PMID:12477932  
PMID:12489207   PMID:12511596   PMID:12556485   PMID:12619036   PMID:12933651   PMID:14668353   PMID:14681479   PMID:15616563   PMID:15721138   PMID:15761081   PMID:15862298   PMID:16002520  
PMID:16141072   PMID:16293667   PMID:16338473   PMID:16416089   PMID:16452166   PMID:16602821   PMID:17062566   PMID:17077188   PMID:17169417   PMID:17255210   PMID:17693389   PMID:17697936  
PMID:18056423   PMID:18340042   PMID:18450962   PMID:18466921   PMID:18554416   PMID:18722179   PMID:18827440   PMID:19683511   PMID:20412791   PMID:21135503   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:21903863   PMID:22653858   PMID:22843786   PMID:23525041   PMID:23563309   PMID:23813480   PMID:24152801   PMID:24952961   PMID:25869614   PMID:26134413   PMID:26446156  
PMID:26456333   PMID:27732088   PMID:27861515   PMID:28617951   PMID:29438518   PMID:29867121   PMID:30301918   PMID:32993096   PMID:33505018   PMID:34292881   PMID:35741102   PMID:36326689  
PMID:36825684   PMID:37296072  


Genomics

Comparative Map Data
Igfbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,147,787 - 7,152,546 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl117,147,782 - 7,152,546 (+)EnsemblGRCm39 Ensembl
GRCm38117,197,787 - 7,202,546 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,197,782 - 7,202,546 (+)EnsemblGRCm38mm10GRCm38
MGSCv37117,097,790 - 7,102,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36117,097,785 - 7,102,539 (+)NCBIMGSCv36mm8
Celera117,672,987 - 7,677,746 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.75NCBI
IGFBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38745,888,488 - 45,893,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl745,888,360 - 45,893,660 (+)EnsemblGRCh38hg38GRCh38
GRCh37745,928,087 - 45,933,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,894,484 - 45,899,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 34745,701,326 - 45,706,499NCBI
Celera746,026,880 - 46,032,188 (+)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef745,812,919 - 45,818,173 (+)NCBIHuRef
CHM1_1745,932,162 - 45,937,470 (+)NCBICHM1_1
T2T-CHM13v2.0746,047,763 - 46,055,379 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,967,292 - 45,972,600 (+)NCBI
Igfbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81486,261,277 - 86,266,344 (+)NCBIGRCr8
mRatBN7.21482,047,415 - 82,052,482 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1482,047,415 - 82,052,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1486,448,608 - 86,453,531 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,688,457 - 87,693,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01484,137,002 - 84,142,071 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01487,448,716 - 87,453,783 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,448,692 - 87,453,785 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,083,056 - 81,088,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,950,222 - 87,955,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11487,969,366 - 87,974,434 (+)NCBI
Celera1481,092,381 - 81,126,760 (+)NCBICelera
RH 3.4 Map14605.9RGD
Cytogenetic Map14q21NCBI
Igfbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,810,056 - 6,815,685 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554566,810,461 - 6,814,944 (-)NCBIChiLan1.0ChiLan1.0
IGFBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2650,770,502 - 50,778,799 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1799,095,242 - 99,103,537 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0746,538,566 - 46,545,536 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1746,657,834 - 46,663,158 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl746,658,097 - 46,662,584 (+)Ensemblpanpan1.1panPan2
IGFBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,037,169 - 1,040,996 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,037,162 - 1,167,094 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha161,813,131 - 1,816,855 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0161,023,782 - 1,027,506 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl161,023,782 - 1,153,699 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1161,014,419 - 1,018,140 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.016950,042 - 953,757 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.016220,948 - 224,674 (+)NCBIUU_Cfam_GSD_1.0
Igfbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118101,282,472 - 101,287,845 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647820,494,203 - 20,499,001 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647820,494,190 - 20,499,001 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGFBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,018,487 - 50,022,799 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,018,487 - 50,022,799 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21854,862,385 - 54,866,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGFBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,932,727 - 12,939,078 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2112,932,732 - 12,937,891 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660629,598,999 - 9,604,182 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igfbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247406,893,867 - 6,897,377 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247406,893,334 - 6,897,591 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Igfbp1
134 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:151
Count of miRNA genes:131
Interacting mature miRNAs:141
Transcripts:ENSMUST00000020704
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse
1357518Tgyl1_mtriglyceride level 1 (mouse)Not determined11688027733916219Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
27226794Feml9_mfemur length 9, 5 week (mouse)11705000016750000Mouse

Markers in Region
PMC141131P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,197,723 - 7,198,333UniSTSGRCm38
MGSCv37117,097,726 - 7,098,336UniSTSGRCm37
Celera117,672,923 - 7,673,533UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.3UniSTS
X81579  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
cM Map111.3UniSTS
Whitehead/MRC_RH1150.81UniSTS
Igfbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,199,803 - 7,199,912UniSTSGRCm38
MGSCv37117,099,806 - 7,099,915UniSTSGRCm37
Celera117,675,003 - 7,675,112UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.3UniSTS
cM Map111.3UniSTS
Igfbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
Igfbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,198,201 - 7,199,861UniSTSGRCm38
MGSCv37117,098,204 - 7,099,864UniSTSGRCm37
Celera117,673,401 - 7,675,061UniSTS
Cytogenetic Map11A1UniSTS
cM Map111.3UniSTS
Igfbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,200,872 - 7,201,946UniSTSGRCm38
MGSCv37117,100,875 - 7,101,949UniSTSGRCm37
Celera117,676,072 - 7,677,146UniSTS
Cytogenetic Map11A1UniSTS
Igfbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
Igfbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38117,198,297 - 7,199,794UniSTSGRCm38
MGSCv37117,098,300 - 7,099,797UniSTSGRCm37
Celera117,673,497 - 7,674,994UniSTS
Cytogenetic Map11A1UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000020704   ⟹   ENSMUSP00000020704
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl117,147,782 - 7,152,546 (+)Ensembl
GRCm38.p6 Ensembl117,197,782 - 7,202,546 (+)Ensembl
RefSeq Acc Id: NM_008341   ⟹   NP_032367
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39117,147,787 - 7,152,546 (+)NCBI
GRCm38117,197,787 - 7,202,546 (+)ENTREZGENE
MGSCv37117,097,790 - 7,102,549 (+)RGD
Celera117,672,987 - 7,677,746 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032367 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA47832 (Get FASTA)   NCBI Sequence Viewer  
  CAA57269 (Get FASTA)   NCBI Sequence Viewer  
  EDL40607 (Get FASTA)   NCBI Sequence Viewer  
  EDL40608 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000020704
  ENSMUSP00000020704.8
GenBank Protein P47876 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_032367   ⟸   NM_008341
- Peptide Label: precursor
- UniProtKB: Q5SVY8 (UniProtKB/Swiss-Prot),   Q61732 (UniProtKB/Swiss-Prot),   P47876 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000020704   ⟸   ENSMUST00000020704
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P47876-F1-model_v2 AlphaFold P47876 1-272 view protein structure

Promoters
RGD ID:6821101
Promoter ID:MM_KWN:6400
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver
Transcripts:ENSMUST00000020704
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36117,097,666 - 7,098,166 (+)MPROMDB
RGD ID:8673932
Promoter ID:EPDNEW_M14997
Type:multiple initiation site
Name:Igfbp1_1
Description:Mus musculus insulin-like growth factor binding protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38117,197,787 - 7,197,847EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96436 AgrOrtholog
Ensembl Genes ENSMUSG00000020429 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000020704 ENTREZGENE
  ENSMUST00000020704.8 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.40.20 UniProtKB/Swiss-Prot
  4.10.800.10 UniProtKB/Swiss-Prot
InterPro Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot
  IGFBP-like UniProtKB/Swiss-Prot
  IGFBP1 UniProtKB/Swiss-Prot
  IGFBP_1-6_chordata UniProtKB/Swiss-Prot
  Insulin_GF-bd_Cys-rich_CS UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
  Thyroglobulin_1_sf UniProtKB/Swiss-Prot
KEGG Report mmu:16006 UniProtKB/Swiss-Prot
MGD MGI:96436 ENTREZGENE
NCBI Gene 16006 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN UniProtKB/Swiss-Prot
  INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 UniProtKB/Swiss-Prot
Pfam IGFBP UniProtKB/Swiss-Prot
  Thyroglobulin_1 UniProtKB/Swiss-Prot
PhenoGen Igfbp1 PhenoGen
PRINTS IGFBPFAMILY UniProtKB/Swiss-Prot
  IGFBPFAMILY1 UniProtKB/Swiss-Prot
PROSITE IGFBP_N_1 UniProtKB/Swiss-Prot
  IGFBP_N_2 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_1 UniProtKB/Swiss-Prot
  THYROGLOBULIN_1_2 UniProtKB/Swiss-Prot
SMART SM00121 UniProtKB/Swiss-Prot
  SM00211 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57184 UniProtKB/Swiss-Prot
  SSF57610 UniProtKB/Swiss-Prot
UniProt IBP1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5SVY8 ENTREZGENE
  Q61732 ENTREZGENE
UniProt Secondary Q5SVY8 UniProtKB/Swiss-Prot
  Q61732 UniProtKB/Swiss-Prot