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Gene: Igfbp1 (insulin-like growth factor binding protein 1) Mus musculus
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Symbol: Igfbp1
Name: insulin-like growth factor binding protein 1
Description: Exhibits insulin-like growth factor binding activity. Predicted to be involved in regulation of insulin-like growth factor receptor signaling pathway. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in diabetic angiopathy. Is expressed in several structures, including blastocyst; early embryo; liver; and secondary oocyte. Orthologous to human IGFBP1 (insulin like growth factor binding protein 1); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; insulin-like growth factor signaling pathway; INTERACTS WITH 1,1-dichloroethene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IBP-1; IGF-binding protein 1; insulin-like growth factor binding protein 1 precursor (IGFBP-1) (IBP-1) (IGF-binding protein 1); insulin-like growth factor-binding protein 1
Orthologs:
Homo sapiens (human) : IGFBP1 (insulin like growth factor binding protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Igfbp1 (insulin-like growth factor binding protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igfbp1 (insulin like growth factor binding protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IGFBP1 (insulin like growth factor binding protein 1)
Canis lupus familiaris (dog) : IGFBP1 (insulin like growth factor binding protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igfbp1 (insulin like growth factor binding protein 1)
Sus scrofa (pig) : IGFBP1 (insulin like growth factor binding protein 1)
Chlorocebus sabaeus (green monkey) : IGFBP1 (insulin like growth factor binding protein 1)
Heterocephalus glaber (naked mole-rat) : Igfbp1 (insulin like growth factor binding protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl117,197,782 - 7,202,546 (+)Ensembl
GRCm38117,197,787 - 7,202,546 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37117,097,790 - 7,102,549 (+)NCBIGRCm37mm9NCBIm37
MGSCv36117,097,785 - 7,102,539 (+)NCBImm8
Celera117,672,987 - 7,677,746 (+)NCBICelera
Cytogenetic Map11 A1NCBI
cM Map114.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Igfbp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69039
Created: 2001-11-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.