IGFBP1 (insulin like growth factor binding protein 1) - Rat Genome Database

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Gene: IGFBP1 (insulin like growth factor binding protein 1) Chlorocebus sabaeus
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Symbol: IGFBP1
Name: insulin like growth factor binding protein 1
RGD ID: 18608636
Description: ENCODES a protein that exhibits growth factor binding (inferred); insulin-like growth factor binding (inferred); insulin-like growth factor I binding (inferred); INVOLVED IN insulin receptor signaling pathway (ortholog); positive regulation of cell growth (ortholog); response to insulin (ortholog); PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; insulin-like growth factor signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Burns (ortholog); Colonic Neoplasms (ortholog); FOUND IN extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: insulin-like growth factor-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,932,727 - 12,939,078 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2112,932,732 - 12,937,891 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660629,598,999 - 9,604,182 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IGFBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,932,727 - 12,939,078 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2112,932,732 - 12,937,891 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660629,598,999 - 9,604,182 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
IGFBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38745,888,488 - 45,893,660 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl745,888,360 - 45,893,660 (+)EnsemblGRCh38hg38GRCh38
GRCh37745,928,087 - 45,933,259 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,894,484 - 45,899,792 (+)NCBINCBI36Build 36hg18NCBI36
Build 34745,701,326 - 45,706,499NCBI
Celera746,026,880 - 46,032,188 (+)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef745,812,919 - 45,818,173 (+)NCBIHuRef
CHM1_1745,932,162 - 45,937,470 (+)NCBICHM1_1
T2T-CHM13v2.0746,047,763 - 46,055,379 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,967,292 - 45,972,600 (+)NCBI
Igfbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,147,787 - 7,152,546 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl117,147,782 - 7,152,546 (+)EnsemblGRCm39 Ensembl
GRCm38117,197,787 - 7,202,546 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,197,782 - 7,202,546 (+)EnsemblGRCm38mm10GRCm38
MGSCv37117,097,790 - 7,102,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36117,097,785 - 7,102,539 (+)NCBIMGSCv36mm8
Celera117,672,987 - 7,677,746 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.75NCBI
Igfbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81486,261,277 - 86,266,344 (+)NCBIGRCr8
mRatBN7.21482,047,415 - 82,052,482 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1482,047,415 - 82,052,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1486,448,608 - 86,453,531 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,688,457 - 87,693,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01484,137,002 - 84,142,071 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01487,448,716 - 87,453,783 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,448,692 - 87,453,785 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,083,056 - 81,088,123 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41487,950,222 - 87,955,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11487,969,366 - 87,974,434 (+)NCBI
Celera1481,092,381 - 81,126,760 (+)NCBICelera
RH 3.4 Map14605.9RGD
Cytogenetic Map14q21NCBI
Igfbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,810,056 - 6,815,685 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554566,810,461 - 6,814,944 (-)NCBIChiLan1.0ChiLan1.0
IGFBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2650,770,502 - 50,778,799 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1799,095,242 - 99,103,537 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0746,538,566 - 46,545,536 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1746,657,834 - 46,663,158 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl746,658,097 - 46,662,584 (+)Ensemblpanpan1.1panPan2
IGFBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,037,169 - 1,040,996 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,037,162 - 1,167,094 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha161,813,131 - 1,816,855 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0161,023,782 - 1,027,506 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl161,023,782 - 1,153,699 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1161,014,419 - 1,018,140 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.016950,042 - 953,757 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.016220,948 - 224,674 (+)NCBIUU_Cfam_GSD_1.0
Igfbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118101,282,472 - 101,287,845 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647820,494,203 - 20,499,001 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647820,494,190 - 20,499,001 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGFBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,018,487 - 50,022,799 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11850,018,487 - 50,022,799 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21854,862,385 - 54,866,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Igfbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247406,893,867 - 6,897,377 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247406,893,334 - 6,897,591 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
38 16 17 28 28 27 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_007981390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACDXN010000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCSAT00000013853   ⟹   ENSCSAP00000011840
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2112,932,732 - 12,937,891 (-)Ensembl
RefSeq Acc Id: XM_007981390   ⟹   XP_007979581
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12112,932,727 - 12,939,078 (-)NCBI
Vero_WHO_p1.0NW_0236660629,598,999 - 9,604,182 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007979581 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000011840
  ENSCSAP00000011840.1
RefSeq Acc Id: XP_007979581   ⟸   XM_007981390
- UniProtKB: A0A0D9RTA1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000011840   ⟸   ENSCSAT00000013853


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000015758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000013853.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.40.20 UniProtKB/TrEMBL
  4.10.800.10 UniProtKB/TrEMBL
InterPro Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  IGFBP-like UniProtKB/TrEMBL
  IGFBP1 UniProtKB/TrEMBL
  IGFBP_1-6_chordata UniProtKB/TrEMBL
  Insulin_GF-bd_Cys-rich_CS UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
  Thyroglobulin_1_sf UniProtKB/TrEMBL
KEGG Report csab:103226114 UniProtKB/TrEMBL
NCBI Gene IGFBP1 ENTREZGENE
PANTHER INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN UniProtKB/TrEMBL
  INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 1 UniProtKB/TrEMBL
Pfam IGFBP UniProtKB/TrEMBL
  Thyroglobulin_1 UniProtKB/TrEMBL
PRINTS IGFBPFAMILY UniProtKB/TrEMBL
  IGFBPFAMILY1 UniProtKB/TrEMBL
PROSITE IGFBP_N_1 UniProtKB/TrEMBL
  IGFBP_N_2 UniProtKB/TrEMBL
  THYROGLOBULIN_1_1 UniProtKB/TrEMBL
  THYROGLOBULIN_1_2 UniProtKB/TrEMBL
SMART SM00121 UniProtKB/TrEMBL
  SM00211 UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
  SSF57610 UniProtKB/TrEMBL
UniProt A0A0D9RTA1 ENTREZGENE, UniProtKB/TrEMBL