Pfkl (phosphofructokinase, liver, B-type) - Rat Genome Database

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Gene: Pfkl (phosphofructokinase, liver, B-type) Mus musculus
Analyze
Symbol: Pfkl
Name: phosphofructokinase, liver, B-type
RGD ID: 731399
MGI Page MGI
Description: Enables 6-phosphofructokinase activity. Acts upstream of or within several processes, including fructose 6-phosphate metabolic process; glycolytic process through fructose-6-phosphate; and negative regulation of insulin secretion. Located in cytosol. Is expressed in several structures, including alimentary system; brain; genitourinary system; musculoskeletal system; and sensory organ. Orthologous to human PFKL (phosphofructokinase, liver type); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; glycolysis pathway; INTERACTS WITH 1,2-dimethylhydrazine; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 6-phosphofructokinase type B; 6-phosphofructokinase, liver type; AA407869; ATP-dependent 6-phosphofructokinase, liver type; ATP-PFK; PFK-B; PFK-L; phosphofructo-1-kinase isozyme B; phosphofructokinase 1; phosphohexokinase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,822,781 - 77,845,641 (-)NCBIGRCm39mm39
GRCm39 Ensembl1077,822,781 - 77,845,917 (-)Ensembl
GRCm381077,986,947 - 78,009,807 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1077,986,947 - 78,010,083 (-)EnsemblGRCm38mm10GRCm38
MGSCv371077,449,692 - 77,472,541 (-)NCBIGRCm37mm9NCBIm37
MGSCv361077,390,400 - 77,412,878 (-)NCBImm8
Celera1079,025,947 - 79,048,797 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
1,4-benzoquinone  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1H-pyrazole  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP)
aflatoxin B2  (ISO)
aluminium phosphide  (ISO)
ammonium chloride  (ISO)
aristolochic acid  (EXP,ISO)
benzo[a]pyrene  (EXP)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
captan  (EXP)
carbon nanotube  (EXP)
chlordecone  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
Diosbulbin B  (EXP)
dioxygen  (EXP)
doxorubicin  (ISO)
elemental selenium  (ISO)
Enterolactone  (ISO)
ethanol  (EXP,ISO)
fluoranthene  (EXP)
flutamide  (EXP)
folic acid  (EXP)
folpet  (EXP)
fructose  (ISO)
ivermectin  (EXP,ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nickel dichloride  (EXP)
nickel subsulfide  (EXP)
nitrofen  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenylephrine  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (EXP)
ranitidine  (ISO)
rotenone  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
tert-butyl hydroperoxide  (EXP)
Tesaglitazar  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
topotecan  (ISO)
trimellitic anhydride  (EXP)
troglitazone  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
Yessotoxin  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
6-phosphofructokinase complex  (IBA,ISO)
cytoplasm  (IEA)
cytosol  (IDA,ISO)
membrane  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:1850735   PMID:2521854   PMID:2533063   PMID:2969893   PMID:6450202   PMID:7549935   PMID:7851892   PMID:7916323   PMID:8172601   PMID:8812488   PMID:9287040   PMID:9545490  
PMID:9878246   PMID:10022980   PMID:10049735   PMID:10051316   PMID:10349636   PMID:10430593   PMID:10613844   PMID:10862698   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11137296  
PMID:11544199   PMID:12477932   PMID:12520002   PMID:14681479   PMID:15747579   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16959763   PMID:17626619   PMID:18799693  
PMID:20185832   PMID:21074528   PMID:21267068   PMID:21270129   PMID:21677750   PMID:21873635   PMID:22922362   PMID:24457600   PMID:24721909   PMID:25340873   PMID:26398943   PMID:27215380  
PMID:27689697   PMID:27746211   PMID:27889896   PMID:28049690   PMID:28245920   PMID:28378742   PMID:29655163   PMID:30068389   PMID:30333137   PMID:30409970   PMID:30457570   PMID:30550785  
PMID:30562941   PMID:32325033   PMID:32581705  


Genomics

Comparative Map Data
Pfkl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,822,781 - 77,845,641 (-)NCBIGRCm39mm39
GRCm39 Ensembl1077,822,781 - 77,845,917 (-)Ensembl
GRCm381077,986,947 - 78,009,807 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1077,986,947 - 78,010,083 (-)EnsemblGRCm38mm10GRCm38
MGSCv371077,449,692 - 77,472,541 (-)NCBIGRCm37mm9NCBIm37
MGSCv361077,390,400 - 77,412,878 (-)NCBImm8
Celera1079,025,947 - 79,048,797 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
PFKL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2144,300,051 - 44,327,376 (+)EnsemblGRCh38hg38GRCh38
GRCh382144,300,040 - 44,327,373 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372145,719,936 - 45,747,256 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,544,358 - 44,571,689 (+)NCBINCBI36hg18NCBI36
Build 342144,544,357 - 44,571,684NCBI
Celera2130,825,177 - 30,852,489 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,062,995 - 31,117,561 (+)NCBIHuRef
CHM1_12145,280,766 - 45,308,102 (+)NCBICHM1_1
Pfkl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22010,664,285 - 10,686,324 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2010,664,272 - 10,686,315 (+)Ensembl
Rnor_6.02011,393,860 - 11,415,889 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,393,877 - 11,415,882 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02013,563,748 - 13,585,941 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42011,009,359 - 11,032,511 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12011,009,585 - 11,032,737 (+)NCBI
Celera2012,170,125 - 12,192,155 (+)NCBICelera
RH 3.4 Map20140.5RGD
Cytogenetic Map20p12NCBI
Pfkl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,131,022 - 41,145,394 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540741,131,022 - 41,145,392 (-)NCBIChiLan1.0ChiLan1.0
PFKL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12143,857,293 - 43,878,380 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2143,857,052 - 43,878,380 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02130,557,576 - 30,584,231 (+)NCBIMhudiblu_PPA_v0panPan3
PFKL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13138,153,638 - 38,178,741 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3138,156,451 - 38,178,507 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3137,313,615 - 37,335,899 (+)NCBI
ROS_Cfam_1.03137,703,738 - 37,726,021 (+)NCBI
UMICH_Zoey_3.13137,570,896 - 37,593,253 (+)NCBI
UNSW_CanFamBas_1.03137,551,678 - 37,573,926 (+)NCBI
UU_Cfam_GSD_1.03138,049,651 - 38,071,966 (+)NCBI
Pfkl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497137,350,253 - 37,373,807 (+)NCBI
SpeTri2.0NW_00493650094,016 - 117,598 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFKL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13207,167,372 - 207,191,690 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113207,167,287 - 207,191,688 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213217,047,266 - 217,071,450 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PFKL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,035,409 - 88,063,376 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl288,035,347 - 88,063,442 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605416,150,512 - 16,178,473 (+)NCBIVero_WHO_p1.0
Pfkl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474529,826,202 - 29,842,859 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH124641  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381077,988,088 - 77,988,186UniSTSGRCm38
MGSCv371077,450,833 - 77,450,931UniSTSGRCm37
Celera1079,027,088 - 79,027,186UniSTS
Cytogenetic Map10C1UniSTS
cM Map1041.7UniSTS
Pfkl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10C1UniSTS
cM Map1041.7UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357740Obsty3_mobesity 3 (mouse)Not determined108359714116355075Mouse
1301386Sysbp1_msystolic blood pressure 1 (mouse)Not determined101023252187565233Mouse
1357825Kidpq2_mkidney weight percentage QTL 2 (mouse)Not determined101282830784243920Mouse
1357656Hrtq3_mheart weight QTL 3 (mouse)Not determined101282830784243920Mouse
1357864Scfpq1_msubcutaneous fat pad percentage QTL 1 (mouse)Not determined101282830784243920Mouse
1357893Lvrq4_mliver weight QTL 4 (mouse)Not determined101282830784243920Mouse
4142380W3q11_mweight 3 weeks QTL 11 (mouse)Not determined1282830784243920Mouse
4141943W6q6_mweight 6 weeks QTL 6 (mouse)Not determined1282830784243920Mouse
4141956Egq7_mearly growth QTL 7 (mouse)Not determined1282830784243920Mouse
4142272W10q5_mweight 10 weeks QTL 5 (mouse)Not determined1282830784243920Mouse
39128215Lwq17_mliver weight QTL 17 (mouse)101282830784243920Mouse
1302067Scc9_mcolon tumor susceptibility 9 (mouse)Not determined1018383585125739363Mouse
27226772Tibl13_mtibia length 13, 10 week (mouse)1019000000129800000Mouse
1558757Eae34_mexperimental allergic encephalomyelitis susceptibility 34 (mouse)Not determined1021532255114381325Mouse
26884403Cvht8_mcranial vault height 8, 16 week (mouse)102300000091200000Mouse
26884426Cvht1_mcranial vault height 1, 5 week (mouse)1024800000121200000Mouse
27095911Pglq15_mpelvic girdle length QTL 15, 16 week (mouse)1039300000129800000Mouse
27226764Tibl19_mtibia length 19, 16 week (mouse)1039300000129800000Mouse
26884411Bzwq8_mbi-zygomatic width QTL 8, 10 week (mouse)1045000000116100000Mouse
26884407Bzwq14_mbi-zygomatic width QTL 14, 16 wee (mouse)1045600000120800000Mouse
4142313Angvq1_mangiogenesis by VEGF QTL 1 (mouse)Not determined4684430782655287Mouse
1302150Bbaa18_mB.burgdorferi-associated arthritis 18 (mouse)Not determined104950223383502378Mouse
4142169Pbwg16_mpostnatal body weight growth 16 (mouse)Not determined105001240884012633Mouse
1300597Skull14_mskull morphology 14 (mouse)Not determined105001240884012633Mouse
10045641Jckm3_mjuvenile cystic kidney modifier 3 (mouse)Not determined105001240884012633Mouse
1301966Lifespan2_mlife span 2 (mouse)Not determined105001244384012618Mouse
1357737Hpcr2_mhepatocarcinogen resistance 2 (mouse)Not determined105001244384012618Mouse
1300882Ath17_matherosclerosis 17 (mouse)Not determined105125566085255809Mouse
1301502Eae17_msusceptibility to experimental allergic encephalomyelitis 17 (mouse)Not determined105125566085255809Mouse
1301380Cia8_mcollagen induced arthritis QTL 8 (mouse)Not determined105161730482655287Mouse
14746991Manh68_mmandible shape 68 (mouse)105244466786444667Mouse
1301787Bsc1_mbrain size control 1 (mouse)Not determined105868113592681262Mouse
26884450Sklq15_mskull length QTL 15, 16 week (mouse)1059500000122500000Mouse
13208560Wght9_mweight 9 (mouse)1060000000121000000Mouse
26884424Zlq9_mzygomatic length QTL 9, 16 week (mouse)1064100000116100000Mouse
1302060El3_mepilepsy 3 (mouse)Not determined106565510499655287Mouse
1300533Aem3_manti-erythrocyte autoantibody modifier 3 (mouse)Not determined106565510499655287Mouse
1301737Insq9_minsulin QTL 9 (mouse)Not determined106565510499655287Mouse
1302035Lmb4_mlupus in MRL and B6 F2 cross (mouse)Not determined106701240892422811Mouse
26884447Sklq9_mskull length QTL 9, 10 week (mouse)1067500000111900000Mouse
26884430Zlq5_mzygomatic length QTL 5, 10 week (mouse)1068000000125000000Mouse
26884405Huml2_mhumerus length 2, 5 week (mouse)1069900000132500000Mouse
11039497Ltpr5a_mLeishmania tropica response 5a (mouse)1073671039107671185Mouse
4142107Obrq12_mobesity resistance QTL 12 (mouse)Not determined7415138482655287Mouse
11353832Pcholq4_mplasma cholesterol QTL 4 (mouse)1074151384125680038Mouse
11353843Gluq1_mblood glucose QTL 1 (mouse)1074151384125680038Mouse
1300975Fembrs3_mfemur breaking strength 3 (mouse)Not determined1075502706109502905Mouse
4142137Femwf3_mfemur work to failure 3 (mouse)Not determined75502706109502905Mouse
1357632Vtbt9_mvertebral trabecular bone trait 9 (mouse)Not determined1075502706109502905Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1133
Count of miRNA genes:580
Interacting mature miRNAs:703
Transcripts:ENSMUST00000020522, ENSMUST00000145716, ENSMUST00000148818, ENSMUST00000149271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001358793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC007433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC153507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK008812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185726 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP766623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY068830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY070321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EL605376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03928 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M61210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000020522   ⟹   ENSMUSP00000020522
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,822,781 - 77,845,641 (-)Ensembl
GRCm38.p6 Ensembl1077,986,947 - 78,009,807 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145716   ⟹   ENSMUSP00000151752
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,836,514 - 77,845,917 (-)Ensembl
GRCm38.p6 Ensembl1078,000,680 - 78,010,083 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148818
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,833,071 - 77,835,768 (-)Ensembl
GRCm38.p6 Ensembl1077,997,237 - 77,999,934 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149271
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,826,297 - 77,828,010 (-)Ensembl
GRCm38.p6 Ensembl1077,990,463 - 77,992,176 (-)Ensembl
RefSeq Acc Id: ENSMUST00000218383   ⟹   ENSMUSP00000151375
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,835,727 - 77,845,561 (-)Ensembl
GRCm38.p6 Ensembl1077,999,893 - 78,009,727 (-)Ensembl
RefSeq Acc Id: ENSMUST00000218921
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,832,415 - 77,837,187 (-)Ensembl
GRCm38.p6 Ensembl1077,996,581 - 78,001,353 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220064
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,832,396 - 77,837,313 (-)Ensembl
GRCm38.p6 Ensembl1077,996,562 - 78,001,479 (-)Ensembl
RefSeq Acc Id: ENSMUST00000220304
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1077,843,430 - 77,845,570 (-)Ensembl
GRCm38.p6 Ensembl1078,007,596 - 78,009,736 (-)Ensembl
RefSeq Acc Id: NM_001358793   ⟹   NP_001345722
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391077,822,781 - 77,845,641 (-)NCBI
GRCm381077,986,947 - 78,009,807 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008826   ⟹   NP_032852
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391077,822,781 - 77,845,641 (-)NCBI
GRCm381077,986,947 - 78,009,807 (-)NCBI
MGSCv371077,449,692 - 77,472,541 (-)RGD
Celera1079,025,947 - 79,048,797 (-)RGD
cM Map10 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_032852   ⟸   NM_008826
- Peptide Label: isoform 1
- UniProtKB: P12382 (UniProtKB/Swiss-Prot),   Q8CD98 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001345722   ⟸   NM_001358793
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000151375   ⟸   ENSMUST00000218383
RefSeq Acc Id: ENSMUSP00000020522   ⟸   ENSMUST00000020522
RefSeq Acc Id: ENSMUSP00000151752   ⟸   ENSMUST00000145716
Protein Domains
PFK

Promoters
RGD ID:6819718
Promoter ID:MM_KWN:4705
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Liver,   Lung
Transcripts:OTTMUST00000041171
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361077,454,526 - 77,455,272 (-)MPROMDB
RGD ID:6819719
Promoter ID:MM_KWN:4706
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000041170
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361077,462,071 - 77,462,571 (-)MPROMDB
RGD ID:6819720
Promoter ID:MM_KWN:4707
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000041169,   OTTMUST00000042544
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361077,472,296 - 77,472,796 (-)MPROMDB
RGD ID:8672464
Promoter ID:EPDNEW_M14263
Type:initiation region
Name:Pfkl_1
Description:Mus musculus phosphofructokinase, liver, B-type , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381078,009,746 - 78,009,806EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:97547 AgrOrtholog
Ensembl Genes ENSMUSG00000020277 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000020522 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000151375 UniProtKB/TrEMBL
  ENSMUSP00000151752 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000020522 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000145716 UniProtKB/TrEMBL
  ENSMUST00000218383 UniProtKB/TrEMBL
InterPro 6-Pfructokinase_euk UniProtKB/Swiss-Prot
  ATP_PFK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PFK_vert-type UniProtKB/Swiss-Prot
  Phosphofructokinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphofructokinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKF_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:18641 UniProtKB/Swiss-Prot
MGD MGI:97547 ENTREZGENE
NCBI Gene 18641 ENTREZGENE
Pfam PFK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pfkl PhenoGen
PIRSF ATP_PFK_euk UniProtKB/Swiss-Prot
PRINTS PHFRCTKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PHOSPHOFRUCTOKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53784 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs 6PF1K_euk UniProtKB/Swiss-Prot
UniProt A0A1W2P6Q4_MOUSE UniProtKB/TrEMBL
  A0A1W2P7T1_MOUSE UniProtKB/TrEMBL
  P12382 ENTREZGENE, UniProtKB/Swiss-Prot
  Q8CD98 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q8VDX7 UniProtKB/Swiss-Prot