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Gene: Cyp1a1 (cytochrome P450, family 1, subfamily a, polypeptide 1) Mus musculus
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Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
RGD ID: 10436
Description: Exhibits oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including amine metabolic process; hydrogen peroxide biosynthetic process; and toxin metabolic process. Predicted to localize to mitochondrial inner membrane. Is expressed in several structures, including genitourinary system; liver; maxillary process; spleen; and upper jaw. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); diabetes mellitus (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to human CYP1A1 (cytochrome P450 family 1 subfamily A member 1); PARTICIPATES IN gefitinib pharmacokinetics pathway; phase I biotransformation pathway via cytochrome P450; tamoxifen pharmacokinetics pathway; INTERACTS WITH (+)-Tetrandrine; (-)-demecolcine; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AHH; AHRR; aromatic compound inducible; CP11; Cyp1a2; CYPIA1; cytochrome P450 1A1; cytochrome P450 family 1 subfamily a polypeptide 2; cytochrome P450 form 6; cytochrome P450 subfamily I, polypeptide 1; cytochrome P450, 1a1, aromatic compound inducible; cytochrome P450-C; cytochrome P450-P1; hydroperoxy icosatetraenoate dehydratase; P450-; P450-1
Orthologs:
Homo sapiens (human) : CYP1A1 (cytochrome P450 family 1 subfamily A member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyp1a1 (cytochrome P450, family 1, subfamily a, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102010850 (cytochrome P450 1A1)
Pan paniscus (bonobo/pygmy chimpanzee) : CYP1A1 (cytochrome P450 family 1 subfamily A member 1)
Canis lupus familiaris (dog) : CYP1A1 (cytochrome P450 family 1 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101969148 (cytochrome P450 1A1)
Sus scrofa (pig) : CYP1A1 (cytochrome P450 1A1)
Chlorocebus sabaeus (African green monkey) : CYP1A1 (cytochrome P450 family 1 subfamily A member 1)
Heterocephalus glaber (naked mole-rat) : LOC101707509 (cytochrome P450 1A1)
more info ...
Related Pseudogenes: Cyp1a1-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39957,595,211 - 57,611,107 (+)NCBI
GRCm38957,687,928 - 57,703,824 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl957,687,928 - 57,703,824 (+)EnsemblGRCm38mm10GRCm38
MGSCv37957,535,735 - 57,551,629 (+)NCBIGRCm37mm9NCBIm37
MGSCv36957,486,065 - 57,501,958 (+)NCBImm8
Celera985,889,319 - 85,895,530 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model