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Gene: Cxcl1 (chemokine (C-X-C motif) ligand 1) Mus musculus
Symbol: Cxcl1
Name: chemokine (C-X-C motif) ligand 1
Description: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-chemokine; C-X-C motif chemokine 1; Fsp; gro; Gro1; GRO1 oncogene; growth-regulated alpha protein; KC; KC/GR)-alpha; KC/GRO-alpha; Mgsa; N51; platelet-derived growth factor-inducible protein KC; Scyb1; secretory protein N51
Homo sapiens (human) : CXCL1 (C-X-C motif chemokine ligand 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cxcl1 (C-X-C motif chemokine ligand 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL1 (C-X-C motif chemokine ligand 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38590,891,245 - 90,893,121 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37591,320,271 - 91,322,147 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,966,510 - 91,968,315 (+)NCBImm8
Celera589,035,565 - 89,037,441 (+)NCBICelera
Cytogenetic Map5 E1NCBI
cM Map544.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cxcl1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732415
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.