Cxcl1 (C-X-C motif chemokine ligand 1) - Rat Genome Database

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Gene: Cxcl1 (C-X-C motif chemokine ligand 1) Mus musculus
Analyze
Symbol: Cxcl1
Name: C-X-C motif chemokine ligand 1
RGD ID: 732415
MGI Page MGI
Description: Predicted to enable CXCR chemokine receptor binding activity and chemokine activity. Involved in several processes, including positive regulation of hematopoietic stem cell proliferation; positive regulation of neutrophil mediated killing of fungus; and positive regulation of superoxide anion generation. Located in extracellular space. Is expressed in several structures, including arterial system; liver; nervous system; retina; and small intestine. Orthologous to human CXCL1 (C-X-C motif chemokine ligand 1) and CXCL2 (C-X-C motif chemokine ligand 2).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: alpha-chemokine; C-X-C motif chemokine 1; chemokine (C-X-C motif) ligand 1; F; Fsp; Gr; gro; Gro1; GRO1 oncogene; growth-regulated alpha protein; KC; KC/GR)-alpha; KC/GRO-alpha; Mg; Mgsa; N5; N51; platelet-derived growth factor-inducible protein KC; Scyb; Scyb1; secretory protein N51
RGD Orthologs
Human
Rat
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39591,039,104 - 91,040,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl591,039,100 - 91,040,974 (+)EnsemblGRCm39 Ensembl
GRCm38590,891,245 - 90,893,121 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,891,241 - 90,893,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,320,271 - 91,322,147 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36591,966,510 - 91,968,315 (+)NCBIMGSCv36mm8
Celera589,035,565 - 89,037,441 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (IEP)
Acute Lung Injury  (IEP)
acute necrotizing pancreatitis  (ISO)
Alcoholic Fatty Liver  (IEP)
Alcoholic Liver Diseases  (ISO)
allergic disease  (ISO)
Animal Hepatitis  (ISO)
aspiration pneumonia  (ISO)
asthma  (ISO)
autoimmune hepatitis  (ISO)
bacterial pneumonia  (IEP,ISO)
Brain Injuries  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
chronic obstructive pulmonary disease  (ISO)
common cold  (ISO)
COVID-19  (ISO)
cystic fibrosis  (IEP,ISO)
dilated cardiomyopathy  (ISO)
Endotoxemia  (IEP)
Enteritis  (ISO)
esophageal cancer  (ISO)
Experimental Arthritis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Femoral Fractures  (ISO)
Hemorrhage  (ISO)
Hemorrhagic Shock  (ISO)
Human Influenza  (IEP)
hyperhomocysteinemia  (ISO)
Inflammation  (ISO)
interstitial cystitis  (ISO)
juvenile rheumatoid arthritis  (ISO)
Legionnaires' disease  (IEP)
Liver Neoplasms  (ISO)
Liver Reperfusion Injury  (IEP,ISO)
lung disease  (IEP,ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
plague  (IMP)
pleurisy  (IEP)
Pneumococcal Meningitis  (ISO)
Pneumococcal Pneumonia  (IEP)
pneumonia  (ISO)
prostatitis  (ISO)
pulmonary emphysema  (IEP)
Reperfusion Injury  (IEP,ISO)
respiratory allergy  (ISO)
respiratory syncytial virus infectious disease  (IEP)
severe acute respiratory syndrome  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
Ventricular Dysfunction, Right  (ISO)
viral pneumonia  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-anisomycin  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-colchicine  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dichlorobenzene  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
1-nitropyrene  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-tert-butylhydroquinone  (ISO)
22-Hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-Nitrofluoranthene  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
Actein  (ISO)
aflatoxin B1  (ISO)
alcohol  (EXP)
aldehydo-D-glucosamine  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
amosite asbestos  (ISO)
amphibole asbestos  (ISO)
amphotericin B  (ISO)
andrographolide  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
apocynin  (ISO)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
atrazine  (ISO)
Bardoxolone methyl  (ISO)
Belnacasan  (ISO)
benazepril  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beryllium sulfate  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
budesonide  (ISO)
butanal  (ISO)
butane-2,3-dione  (ISO)
C60 fullerene  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
candesartan  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
cefaloridine  (ISO)
chloropicrin  (ISO)
chondroitin sulfate  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
cobalt(2+) sulfate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
crocidolite asbestos  (ISO)
crotonaldehyde  (ISO)
curcumin  (ISO)
cyanuric chloride  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diisopropyl fluorophosphate  (ISO)
dinitrogen  (ISO)
diuron  (ISO)
divanadium pentaoxide  (ISO)
doramapimod  (ISO)
doxorubicin  (ISO)
edaravone  (ISO)
elemental selenium  (ISO)
emodin  (ISO)
endosulfan  (ISO)
ethanol  (ISO)
eugenol  (ISO)
famotidine  (ISO)
ferric oxide  (ISO)
fluticasone  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gadolinium trichloride  (ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glutathione  (ISO)
gossypol  (ISO)
graphite  (ISO)
halothane  (ISO)
heparan sulfate  (ISO)
hexachlorobenzene  (ISO)
Hexadimethrine bromide  (ISO)
hydrogen chloride  (ISO)
hydrogen peroxide  (ISO)
hydroxychloroquine  (ISO)
idelalisib  (EXP)
indometacin  (ISO)
iron atom  (ISO)
iron(0)  (ISO)
isoflurane  (ISO)
isotretinoin  (ISO)
ketorolac  (ISO)
L-ascorbic acid  (ISO)
lansoprazole  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (ISO)
losartan  (ISO)
manganese(II) chloride  (ISO)
mesalamine  (ISO)
metformin  (ISO)
methadone  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylparaben  (ISO)
metyrapone  (ISO)
microcystin-LR  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
morphine  (ISO)
Muraglitazar  (ISO)
muramyl dipeptide  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodimethylamine  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
naphthalenes  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
o-anisidine  (ISO)
oxaliplatin  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
PD 0325901  (ISO)
pentanal  (ISO)
pentane-2,3-dione  (ISO)
perfluorobutyric acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
Phytolaccoside E  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
poly(I:C)  (ISO)
potassium chromate  (ISO)
prednisolone  (ISO)
Primycin  (ISO)
progesterone  (ISO)
propanal  (ISO)
propylparaben  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quartz  (ISO)
ranitidine  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
ritonavir  (ISO)
rofecoxib  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 203580  (ISO)
SCH-351591  (ISO)
SCH772984  (ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
Soman  (ISO)
spironolactone  (ISO)
streptozocin  (ISO)
sulfapyridine  (ISO)
sulfasalazine  (ISO)
sulforaphane  (ISO)
sulfur dioxide  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetradecane  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
Tiron  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimethyltin  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tropisetron  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
undecane  (ISO)
ursodeoxycholic acid  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
wortmannin  (ISO)
zaragozic acid A  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc protoporphyrin  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
extracellular region  (IEA)
extracellular space  (HDA,IBA,IDA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Neutrophil chemokines and their role in IL-18-mediated increase in neutrophil O2- production and intestinal edema following alcohol intoxication and burn injury. Akhtar S, etal., Am J Physiol Gastrointest Liver Physiol. 2009 Aug;297(2):G340-7. Epub 2009 Jun 4.
2. Impaired interleukin-8 chemokine secretion by staphylococcus aureus-activated epithelium and T-cell chemotaxis in cystic fibrosis. Al Alam D, etal., Am J Respir Cell Mol Biol. 2010 Jun;42(6):644-50. Epub 2009 Jul 13.
3. Role of cytokine-induced neutrophil chemoattractant-2 (CINC-2) alpha in a rat model of chronic bronchopulmonary infections with Pseudomonas aeruginosa. Amano H, etal., Cytokine. 2000 Nov;12(11):1662-8.
4. Splenectomy exacerbates lung injury after ischemic acute kidney injury in mice. Andres-Hernando A, etal., Am J Physiol Renal Physiol. 2011 Oct;301(4):F907-16. Epub 2011 Jun 15.
5. A kinetic study of the cytokine/chemokines levels and disruption of blood-brain barrier in infant rats after pneumococcal meningitis. Barichello T, etal., J Neuroimmunol. 2011 Apr;233(1-2):12-7. Epub 2010 Nov 24.
6. Ischemia-reperfusion of rat myocardium activates nuclear factor-KappaB and induces neutrophil infiltration via lipopolysaccharide-induced CXC chemokine. Chandrasekar B, etal., Circulation. 2001 May 8;103(18):2296-302.
7. Titanium dioxide nanoparticles induce emphysema-like lung injury in mice. Chen HW, etal., FASEB J. 2006 Nov;20(13):2393-5. Epub 2006 Oct 5.
8. Interferon-beta attenuates lung inflammation following experimental subarachnoid hemorrhage. Cobelens PM, etal., Crit Care. 2010;14(4):R157. Epub 2010 Aug 23.
9. The ratio of ELR+ to ELR- CXC chemokines affects the lung and liver injury following hepatic ischemia/ reperfusion in the rat. Colletti LM, etal., Hepatology. 2000 Feb;31(2):435-45.
10. Chemokine receptor CXCR2 mediates bacterial clearance rather than neutrophil recruitment in a murine model of pneumonic plague. Eisele NA, etal., Am J Pathol. 2011 Mar;178(3):1190-200.
11. Impairment of leukocyte trafficking in a murine pleuritis model by IL-4 and IL-10. Fine JS, etal., Inflammation. 2003 Aug;27(4):161-74.
12. The molecular phenotype of severe asthma in children. Fitzpatrick AM, etal., J Allergy Clin Immunol. 2010 Apr;125(4):851-857.e18.
13. Rat respiratory coronavirus infection: replication in airway and alveolar epithelial cells and the innate immune response. Funk CJ, etal., J Gen Virol. 2009 Dec;90(Pt 12):2956-64. Epub 2009 Sep 9.
14. Characterization of the inflammatory response during acute and post-acute phases after severe burn. Gauglitz GG, etal., Shock. 2008 Nov;30(5):503-7.
15. Folic acid treatment reduces chemokine release from peripheral blood mononuclear cells in hyperhomocysteinemic subjects. Holven KB, etal., Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):699-703.
16. Pulmonary contusion primes systemic innate immunity responses. Hoth JJ, etal., J Trauma. 2009 Jul;67(1):14-21; discussion 21-2.
17. Increased expression of the chemokines CXCL1 and MIP-1alpha by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats. Johnson EA, etal., J Neuroinflammation. 2011 May 2;8:41.
18. Attenuation of warm ischemia-reperfusion injury in the liver by bucillamine through decreased neutrophil activation and Bax/Bcl-2 modulation. Junnarkar SP, etal., J Gastroenterol Hepatol. 2010 Dec;25(12):1891-9. doi: 10.1111/j.1440-1746.2010.06312.x.
19. Elucidation of the pathophysiology of interstitial cystitis/bladder pain syndrome via experimental autoimmune cystitis rat model. Kadekawa K, etal., Am J Physiol Regul Integr Comp Physiol. 2024 Aug 1;327(2):R250-R260. doi: 10.1152/ajpregu.00269.2023. Epub 2024 Jun 6.
20. Pharmacological inhibition of p110δ subunit of PI3K confers protection against experimental leishmaniasis. Khadem F, etal., J Antimicrob Chemother. 2017 Feb;72(2):467-477. doi: 10.1093/jac/dkw448. Epub 2016 Dec 20.
21. Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-delta (delta-PKC). Kilpatrick LE, etal., J Leukoc Biol. 2011 Jan;89(1):3-10. Epub 2010 Aug 19.
22. Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Kusumanchi P, etal., Hepatology. 2021 Sep;74(3):1234-1250. doi: 10.1002/hep.31800. Epub 2021 Aug 30.
23. Early combined treatment with sildenafil and adipose-derived mesenchymal stem cells preserves heart function in rat dilated cardiomyopathy. Lin YC, etal., J Transl Med. 2010 Sep 26;8:88.
24. The migration of T cells in response to influenza virus is altered in neonatal mice. Lines JL, etal., J Immunol. 2010 Sep 1;185(5):2980-8. Epub 2010 Jul 23.
25. Ondansetron attenuates hepatic injury via p38 MAPK-dependent pathway in a rat haemorrhagic shock model. Liu FC, etal., Resuscitation. 2011 Mar;82(3):335-40. Epub 2010 Dec 18.
26. Low intensity laser therapy (LILT) in vivo acts on the neutrophils recruitment and chemokines/cytokines levels in a model of acute pulmonary inflammation induced by aerosol of lipopolysaccharide from Escherichia coli in rat. Mafra de Lima F, etal., J Photochem Photobiol B. 2010 Dec 2;101(3):271-8. Epub 2010 Jul 27.
27. CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation. Marcos V, etal., Nat Med. 2010 Sep;16(9):1018-23. Epub 2010 Sep 5.
28. Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury. McTigue DM, etal., J Neurosci Res. 1998 Aug 1;53(3):368-76.
29. MGDs mouse GO annotations MGD data from the GO Consortium
30. Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat. Nanji AA, etal., Hepatology. 1999 Oct;30(4):934-43.
31. Mechanisms of acute inflammatory lung injury induced by abdominal sepsis. Neumann B, etal., Int Immunol. 1999 Feb;11(2):217-27.
32. Cyclooxygenase inhibition in ventilator-induced lung injury. Niitsu T, etal., Anesth Analg. 2011 Jan;112(1):143-9. Epub 2010 Nov 3.
33. Mast cells are involved in the pathogenesis of indomethacin-induced rat enteritis. Okayama T, etal., J Gastroenterol. 2009;44 Suppl 19:35-9. Epub 2009 Jan 16.
34. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
35. Microarray analysis of distinct gene transcription profiles in non-eosinophilic chronic sinusitis with nasal polyps. Payne SC, etal., Am J Rhinol. 2008 Nov-Dec;22(6):568-81.
36. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
37. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
38. Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion. Raghavendran K, etal., J Surg Res. 2009 Aug;155(2):273-82. Epub 2008 Sep 16.
39. Preliminary investigation of a mice model of Klebsiella pneumoniae subsp. ozaenae induced pneumonia. Renois F, etal., Microbes Infect. 2011 Jun 30.
40. Mouse MP Annotation Import Pipeline RGD automated import pipeline
41. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
42. A rat model of picornavirus-induced airway infection and inflammation. Rosenthal LA, etal., Virol J. 2009 Aug 11;6:122.
43. The murine neutrophil-chemoattractant chemokines LIX, KC, and MIP-2 have distinct induction kinetics, tissue distributions, and tissue-specific sensitivities to glucocorticoid regulation in endotoxemia. Rovai LE, etal., J Leukoc Biol. 1998 Oct;64(4):494-502.
44. Effects of aliskiren on stroke in rats expressing human renin and angiotensinogen genes. Schmerbach K, etal., PLoS One. 2010 Nov 29;5(11):e15052.
45. Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease. Schneider D, etal., Am J Respir Crit Care Med. 2010 Aug 1;182(3):332-40. Epub 2010 Apr 15.
46. Correlation of measurable serum markers of inflammation with lung levels following bilateral femur fracture in a rat model. Sears BW, etal., J Inflamm Res. 2010 Aug 1;2010(3):105-114.
47. Protection from pulmonary ischemia-reperfusion injury by adenosine A2A receptor activation. Sharma AK, etal., Respir Res. 2009 Jun 26;10:58.
48. Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice. Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
49. Differential changes in the concentrations of cytokine-induced neutrophil chemoattractant (CINC)-1 and CINC-2 in exudate during rat lipopolysaccharide-induced inflammation. Shibata F, etal., Cytokine. 1996 Mar;8(3):222-6.
50. Induction of pro- and anti-inflammatory molecules in a mouse model of pneumococcal pneumonia after influenza. Smith MW, etal., Comp Med. 2007 Feb;57(1):82-9.
51. The evolving systemic and local biomarker milieu at different stages of disease progression in rat collagen-induced arthritis. Stolina M, etal., Biomarkers. 2008 Nov;13(7):692-712.
52. Multiple berry types prevent N-nitrosomethylbenzylamine-induced esophageal cancer in rats. Stoner GD, etal., Pharm Res. 2010 Jun;27(6):1138-45. Epub 2010 Mar 16.
53. Effect of a phytotherapeutic agent, Eviprostat(R), on prostatic and urinary cytokines/chemokines in a rat model of nonbacterial prostatitis. Sugimoto M, etal., Prostate. 2011 Mar 1;71(4):438-44. doi: 10.1002/pros.21299. Epub 2010 Oct 28.
54. The role of the choroid plexus in neutrophil invasion after traumatic brain injury. Szmydynger-Chodobska J, etal., J Cereb Blood Flow Metab. 2009 Sep;29(9):1503-16. Epub 2009 May 27.
55. Chemokine-dependent neutrophil recruitment in a murine model of Legionella pneumonia: potential role of neutrophils as immunoregulatory cells. Tateda K, etal., Infect Immun. 2001 Apr;69(4):2017-24.
56. Acute exposure of mice to high-dose ultrafine carbon black decreases susceptibility to pneumococcal pneumonia. Tellabati A, etal., Part Fibre Toxicol. 2010 Oct 19;7:30.
57. Dietary (n-3) polyunsaturated fatty acids affect the kinetics of pro- and antiinflammatory responses in mice with Pseudomonas aeruginosa lung infection. Tiesset H, etal., J Nutr. 2009 Jan;139(1):82-9. Epub 2008 Dec 3.
58. Respiratory syncytial virus (RSV) RNA loads in peripheral blood correlates with disease severity in mice. Torres JP, etal., Respir Res. 2010 Sep 15;11:125.
59. The differences of eosinophil- and neutrophil-related inflammation in elderly allergic and non-allergic chronic obstructive pulmonary disease. Tsai JJ, etal., J Asthma. 2010 Nov;47(9):1040-4.
60. The protective function of neutrophil elastase inhibitor in liver ischemia/reperfusion injury. Uchida Y, etal., Transplantation. 2010 May 15;89(9):1050-6.
61. Role of the Fas/FasL system in a model of RSV infection in mechanically ventilated mice. van den Berg E, etal., Am J Physiol Lung Cell Mol Physiol. 2011 Jul 8.
62. [Anti-inflammatory effects of erythropoietin on hyperoxia-induced bronchopulmonary dysplasia in newborn rats]. Wang XL and Xue XD, Zhonghua Er Ke Za Zhi. 2009 Jun;47(6):446-51.
63. Proinflammatory events in right ventricular damage during pulmonary embolism: effects of treatment with ketorolac in rats. Watts JA, etal., J Cardiovasc Pharmacol. 2009 Sep;54(3):246-52.
64. [Effects of N-acetylcysteine on mRNA expression of monocyte chemotactic protein and macrophage inflammatory protein 2 in acute necrotizing pancreatitis: experiment with rats] Xu CF, etal., Zhonghua Yi Xue Za Zhi. 2008 Mar 11;88(10):711-5.
65. Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis. Yang SJ, etal., Injury. 2011 Jul;42(7):638-42. Epub 2010 Aug 14.
66. Role of Akt-dependent up-regulation of hemeoxygenase-1 in resveratrol-mediated attenuation of hepatic injury after trauma hemorrhage. Yu HP, etal., Surgery. 2010 Jul;148(1):103-9. Epub 2010 Feb 1.
67. Mechanisms of dexamethasone-mediated chemokine down-regulation in mild and severe acute pancreatitis. Yubero S, etal., Biochim Biophys Acta. 2009 Dec;1792(12):1205-11. Epub 2009 Oct 7.
Additional References at PubMed
PMID:1315306   PMID:1372902   PMID:1406651   PMID:1543915   PMID:1647018   PMID:1979024   PMID:2575589   PMID:2890161   PMID:2909392   PMID:2917992   PMID:2970963   PMID:3108379  
PMID:6872001   PMID:7561058   PMID:7751647   PMID:7890604   PMID:7961909   PMID:8051420   PMID:8180469   PMID:8558062   PMID:8755666   PMID:8835534   PMID:9365113   PMID:9510207  
PMID:9589353   PMID:9730606   PMID:9730682   PMID:9884514   PMID:10349636   PMID:10570306   PMID:10714680   PMID:10725737   PMID:10843805   PMID:10922068   PMID:11042159   PMID:11076861  
PMID:11217851   PMID:11444905   PMID:11719444   PMID:11739532   PMID:11907123   PMID:12055258   PMID:12080938   PMID:12126650   PMID:12464176   PMID:12477932   PMID:12488493   PMID:12847259  
PMID:14583342   PMID:14988231   PMID:15274748   PMID:15582587   PMID:15597153   PMID:15843382   PMID:15961314   PMID:15994316   PMID:16033775   PMID:16118408   PMID:16141072   PMID:16141073  
PMID:16565511   PMID:16602821   PMID:16618742   PMID:16804897   PMID:16894357   PMID:16964312   PMID:16996102   PMID:17227950   PMID:17237432   PMID:17460147   PMID:17662241   PMID:17673686  
PMID:17911102   PMID:17928531   PMID:18161062   PMID:18322244   PMID:18347102   PMID:18347542   PMID:18490717   PMID:18519646   PMID:18559975   PMID:18619964   PMID:18713728   PMID:18991290  
PMID:19021203   PMID:19095949   PMID:19147675   PMID:19430878   PMID:19494115   PMID:19633199   PMID:19642907   PMID:19806220   PMID:19893623   PMID:19932745   PMID:20007247   PMID:20107187  
PMID:20591742   PMID:20593289   PMID:20671197   PMID:20823213   PMID:20864798   PMID:20937845   PMID:20969841   PMID:21224226   PMID:21257927   PMID:21267068   PMID:21321537   PMID:21383500  
PMID:21438871   PMID:21541502   PMID:21822258   PMID:21873635   PMID:21985298   PMID:22275756   PMID:22277947   PMID:22320712   PMID:22342504   PMID:22379035   PMID:22533966   PMID:22682244  
PMID:22791336   PMID:22952118   PMID:22996693   PMID:23025258   PMID:23334998   PMID:23460747   PMID:23471340   PMID:23520506   PMID:23520553   PMID:23598282   PMID:23645836   PMID:23755134  
PMID:23791889   PMID:23831863   PMID:23864653   PMID:23875831   PMID:23892723   PMID:23967336   PMID:24006456   PMID:24068662   PMID:24081661   PMID:24120921   PMID:24186876   PMID:24196571  
PMID:24442436   PMID:24650562   PMID:24887006   PMID:24913232   PMID:24920846   PMID:24928936   PMID:25041478   PMID:25063677   PMID:25084278   PMID:25093679   PMID:25105129   PMID:25114117  
PMID:25114278   PMID:25172493   PMID:25209981   PMID:25445193   PMID:25559893   PMID:25563839   PMID:25930080   PMID:25956904   PMID:26034212   PMID:26138727   PMID:26252654   PMID:26311113  
PMID:26332085   PMID:26349659   PMID:26514298   PMID:26613766   PMID:26689285   PMID:26747783   PMID:26871571   PMID:26934670   PMID:27002851   PMID:27027573   PMID:27049944   PMID:27189410  
PMID:27193261   PMID:27241286   PMID:27286792   PMID:27454298   PMID:27488521   PMID:27625115   PMID:27694478   PMID:27760760   PMID:27779193   PMID:27809288   PMID:27883091   PMID:28096401  
PMID:28574501   PMID:28739876   PMID:28791835   PMID:28863006   PMID:28922428   PMID:28960786   PMID:29180744   PMID:29309879   PMID:29391475   PMID:29476069   PMID:29539416   PMID:29798841  
PMID:30094610   PMID:30146158   PMID:30175527   PMID:30248108   PMID:30294880   PMID:30446388   PMID:30571485   PMID:30723078   PMID:30996332   PMID:31146911   PMID:31260126   PMID:31260451  
PMID:31388880   PMID:31519886   PMID:31519887   PMID:31600168   PMID:31699822   PMID:31712428   PMID:32229220   PMID:32708537   PMID:32708917   PMID:32881070   PMID:32937134   PMID:33067103  
PMID:33371364   PMID:33412104   PMID:33763067   PMID:33897880   PMID:34011393   PMID:34195684   PMID:34686752   PMID:34714950   PMID:34899755   PMID:34905516   PMID:35304656   PMID:35388502  
PMID:35726058   PMID:35859175   PMID:35981418   PMID:36401162   PMID:36414671   PMID:36640323   PMID:36867134   PMID:36929654   PMID:36930735   PMID:37058471   PMID:37175837   PMID:37225978  
PMID:37708451   PMID:38071977   PMID:38355793   PMID:38395995   PMID:38493581   PMID:38816193  


Genomics

Comparative Map Data
Cxcl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39591,039,104 - 91,040,980 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl591,039,100 - 91,040,974 (+)EnsemblGRCm39 Ensembl
GRCm38590,891,245 - 90,893,121 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,891,241 - 90,893,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,320,271 - 91,322,147 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36591,966,510 - 91,968,315 (+)NCBIMGSCv36mm8
Celera589,035,565 - 89,037,441 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
CXCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38473,869,393 - 73,871,308 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl473,869,393 - 73,871,308 (+)EnsemblGRCh38hg38GRCh38
GRCh37474,735,110 - 74,737,025 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36474,953,973 - 74,955,817 (+)NCBINCBI36Build 36hg18NCBI36
Build 34475,100,143 - 75,101,988NCBI
Celera472,095,237 - 72,097,087 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef470,546,248 - 70,548,158 (+)NCBIHuRef
CHM1_1474,771,032 - 74,772,942 (+)NCBICHM1_1
T2T-CHM13v2.0477,213,030 - 77,214,945 (+)NCBIT2T-CHM13v2.0
Cxcl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81417,477,542 - 17,479,321 (-)NCBIGRCr8
mRatBN7.21417,193,364 - 17,195,143 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,193,365 - 17,195,215 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,194,186 - 17,195,964 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,513,114 - 18,514,892 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,205,210 - 17,206,989 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01418,743,678 - 18,745,457 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1418,743,685 - 18,745,457 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01418,653,032 - 18,654,811 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,690,339 - 18,692,118 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11418,690,338 - 18,692,118 (-)NCBI
Celera1416,570,160 - 16,571,939 (-)NCBICelera
RH 3.4 Map14215.0RGD
Cytogenetic Map14p22NCBI
LOC100976904
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2356,193,010 - 56,195,078 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1456,382,200 - 56,384,184 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0450,325,248 - 50,327,165 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1456,157,626 - 56,159,522 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl456,153,899 - 56,159,474 (-)Ensemblpanpan1.1panPan2
CXCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1722,327,041 - 22,329,405 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl722,569,355 - 22,569,900 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
ChlSab1.1 Ensembl722,327,508 - 22,328,959 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666084462,274 - 464,225 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Cxcl1
73 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:190
Count of miRNA genes:152
Interacting mature miRNAs:164
Transcripts:ENSMUST00000031327
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
1301010ahl2_mage related hearing loss 2 (mouse)Not determined56265056896650688Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
12910784Pwgrq15_mpost-weaning growth rate QTL 15 (mouse)57717582397658215Mouse
1301524Lmb2_mlupus in MRL and B6 F2 cross (mouse)Not determined537581488112465722Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
10045972Tir5_mtrypanosome infection response 5 (mouse)Not determined563705442104387065Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
12910816Ogrq2_moverall growth rate QTL 2 (mouse)57717582397658215Mouse
1301691Cdcs10_mcytokine deficiency colitis susceptibility 10 (mouse)Not determined576280786110280917Mouse
11041665Lmr24_mleishmaniasis resistance 24 (mouse)552694462107321041Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
11252124Modvl6_mmodifier of vacuolated lens 6 (mouse)56265056896650688Mouse
1301419Cypr3_mcytokine production 3 (mouse)Not determined581019649115019803Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1301843Listr1_mlisteriosis resistance 1 (mouse)Not determined56024608194246203Mouse
10043993Hbnr10_mHeligmosomoides bakeri nematode resistance 10 (mouse)Not determined572418876106419011Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
10401246Bglu13_mblood glucose level 13 (mouse)Not determined579539640113539786Mouse
4141438Skmw13_mskeletal muscle weight 13 (mouse)Not determined576190263110190479Mouse
1301713Dbsty2_mdiabesity 2 (mouse)Not determined576445064110445225Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
11041899Lmr24a_mleishmaniasis resistance 24a (mouse)552694462107321041Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
1300931Cocrb6_mcocaine related behavior 6 (mouse)Not determined576445064110445225Mouse
4142317Rgcs1_mretinal ganglion cell susceptible 1 (mouse)Not determined55388334108762627Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301829Thyls2_mthymic lymphoma susceptibility 2 (mouse)Not determined576445064110445225Mouse
12904740M1fscn2_mmodifier 1 of Fscn2 (mouse)566529661100529661Mouse
10755524Mono1_mmonocyte differential 1 (mouse)580849259114849259Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
4142428Modvl1_mmodifier of vacuolated lens 1 (mouse)Not determined6265056896650688Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
11040589Lmr3a_mleishmaniasis resistance 3a (mouse)55960280193602980Mouse
11040590Lmr3b_mleishmaniasis resistance 3b (mouse)55960280193602980Mouse
11040591Lmr3c_mleishmaniasis resistance 3c (mouse)55960280193602980Mouse
12904739M2fscn2_mmodifier 2 of FSCN2 (mouse)566529661100529661Mouse
1301243Bmd2_mbone mineral density 2 (mouse)Not determined555388334100455525Mouse
1300986Hdlq2_mHDL QTL 2 (mouse)Not determined576280786110280917Mouse
11049560Lmr24d_mleishmaniasis resistance 24d (mouse)56437487798374996Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
13464249Ahl16_mage related hearing loss, early onset 16 (mouse)576445064110445225Mouse
13464250Ahl15_mage related hearing loss, early onset 15 (mouse)56265056896650688Mouse
11040592Lmr3d_mleishmaniasis resistance 3d (mouse)55960280193602980Mouse
13464247Ahl14_mage related hearing loss, early onset 14 (mouse)56040306294403160Mouse
4141124Dshv2_mdorsal hippocampal volume 2 (mouse)Not determined57531534898019803Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
10044005Ahl7_mage related hearing loss 7 (mouse)Not determined55833050292330641Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
4141505Chlq14_mcirculating hormone level QTL 14 (mouse)Not determined576280786110280917Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse

Markers in Region
PMC108388P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,892,522 - 90,893,052UniSTSGRCm38
MGSCv37591,321,548 - 91,322,078UniSTSGRCm37
Celera589,036,842 - 89,037,372UniSTS
Cytogenetic Map5E-FUniSTS
PMC108388P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,892,563 - 90,893,052UniSTSGRCm38
MGSCv37591,321,589 - 91,322,078UniSTSGRCm37
Celera589,036,883 - 89,037,372UniSTS
Cytogenetic Map5E-FUniSTS
Gro1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38590,891,546 - 90,892,529UniSTSGRCm38
MGSCv37591,320,572 - 91,321,555UniSTSGRCm37
Celera589,035,866 - 89,036,849UniSTS
Cytogenetic Map5E-FUniSTS
cM Map551.0UniSTS
Cxcl1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5E-FUniSTS


Sequence


Ensembl Acc Id: ENSMUST00000031327   ⟹   ENSMUSP00000031327
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,039,100 - 91,040,974 (+)Ensembl
GRCm38.p6 Ensembl590,891,241 - 90,893,115 (+)Ensembl
Ensembl Acc Id: ENSMUST00000201245
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl591,039,102 - 91,040,972 (+)Ensembl
GRCm38.p6 Ensembl590,891,243 - 90,893,113 (+)Ensembl
RefSeq Acc Id: NM_008176   ⟹   NP_032202
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39591,039,104 - 91,040,980 (+)NCBI
GRCm38590,891,245 - 90,893,121 (+)ENTREZGENE
MGSCv37591,320,271 - 91,322,147 (+)RGD
Celera589,035,565 - 89,037,441 (+)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032202   ⟸   NM_008176
- Peptide Label: precursor
- UniProtKB: P12850 (UniProtKB/Swiss-Prot),   A2RTH0 (UniProtKB/TrEMBL),   Q5U5W9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000031327   ⟸   ENSMUST00000031327
Protein Domains
Chemokine interleukin-8-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P12850-F1-model_v2 AlphaFold P12850 1-96 view protein structure

Promoters
RGD ID:6887128
Promoter ID:EPDNEW_M7015
Type:multiple initiation site
Name:Cxcl1_1
Description:Mus musculus chemokine (C-X-C motif) ligand 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38590,891,243 - 90,891,303EPDNEW
RGD ID:6837316
Promoter ID:MM_KWN:42849
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Liver,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000040923
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36591,320,081 - 91,320,622 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108068 AgrOrtholog
Ensembl Genes ENSMUSG00000029380 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000031327 ENTREZGENE
  ENSMUST00000031327.9 UniProtKB/Swiss-Prot
Gene3D-CATH 2.40.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CXC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CXC_Chemokine_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14825 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:108068 ENTREZGENE
NCBI Gene 14825 ENTREZGENE
PANTHER GROWTH-REGULATED ALPHA PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMALL INDUCIBLE CYTOKINE A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cxcl1 PhenoGen
PRINTS INTERLEUKIN8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMALLCYTKCXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SMALL_CYTOKINES_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2RTH0 ENTREZGENE, UniProtKB/TrEMBL
  GROA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5U5W9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Cxcl1  C-X-C motif chemokine ligand 1  Cxcl1  chemokine (C-X-C motif) ligand 1  Symbol and/or name change 5135510 APPROVED