Ruvbl1 (RuvB-like protein 1) - Rat Genome Database

Name: Ruvbl1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ruvbl1 (RuvB-like protein 1) Mus musculus

Analyze

Symbol:

Ruvbl1

Name:

RuvB-like protein 1

RGD ID:

68538

MGI Page

MGI

Description:

Is expressed in several structures, including branchial arch; limb; liver; maxillary process; and sensory organ. Orthologous to human RUVBL1 (RuvB like AAA ATPase 1); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; Wnt signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

2510009G06Rik; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; DNA helicase p50; Pon; Pontin 52; Pontin52; ruvB-like 1; Tip; Tip49a

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RUVBL1 (RuvB like AAA ATPase 1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Rattus norvegicus (Norway rat):	Ruvbl1 (RuvB-like AAA ATPase 1)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Ruvbl1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RUVBL1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RUVBL1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ruvbl1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RUVBL1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	RUVBL1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ruvbl1 (RuvB like AAA ATPase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Ruvbl1 (RuvB-like AAA ATPase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Homo sapiens (human):	RUVBL1 (RuvB like AAA ATPase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)
Danio rerio (zebrafish):	ruvbl1 (RuvB-like AAA ATPase 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam\|ZFIN)
Caenorhabditis elegans (roundworm):	ruvb-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	RVB1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	pont	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)

Related Pseudogenes:

Gm3086 Gm5837 Gm7499

Latest Assembly:

GRCm38 - Mouse Genome Assembly GRCm38

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	88,442,391 - 88,474,548 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	88,442,391 - 88,474,554 (+)	Ensembl
GRCm38	6	88,465,409 - 88,497,566 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	88,465,409 - 88,497,572 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	88,415,417 - 88,447,560 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	88,431,107 - 88,463,207 (+)	NCBI			mm8
Celera	6	90,403,044 - 90,439,348 (+)	NCBI		Celera
Cytogenetic Map	6	D1	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (ISO)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dinitrotoluene (ISO)

2,6-dinitrotoluene (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

4-amino-2,6-dinitrotoluene (ISO)

5-aza-2'-deoxycytidine (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (ISO)

antirheumatic drug (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (ISO)

bleomycin A5 (ISO)

captan (EXP)

ceruletide (ISO)

chromium(6+) (EXP)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

disodium selenite (ISO)

dopamine (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

ethyl methanesulfonate (ISO)

finasteride (ISO)

flavonoids (ISO)

flutamide (ISO)

geraniol (ISO)

glyphosate (ISO)

methyl methanesulfonate (ISO)

N-methyl-N'-nitro-N-nitrosoguanidine (ISO)

nickel atom (ISO)

ochratoxin A (ISO)

oxaliplatin (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (EXP)

pirinixic acid (EXP)

progesterone (ISO)

quercetin (ISO)

selenium atom (ISO)

sodium arsenite (ISO)

T-2 toxin (ISO)

tetrachloromethane (ISO)

thioacetamide (ISO)

topotecan (ISO)

trimellitic anhydride (EXP)

urethane (ISO)

valproic acid (EXP,ISO)

zinc dichloride (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

box C/D snoRNP assembly (IBA)

cell division (IEA)

cellular response to DNA damage stimulus (IEA)

chromatin organization (IEA)

chromatin remodeling (IBA)

DNA recombination (IEA)

DNA repair (IEA)

histone acetylation (IBA)

histone H2A acetylation (ISO)

histone H4 acetylation (ISO)

positive regulation of canonical Wnt signaling pathway (ISO)

positive regulation of plasminogen activation (ISO)

positive regulation of telomerase RNA localization to Cajal body (ISO)

regulation of fibroblast apoptotic process (ISO)

regulation of growth (IEA)

regulation of transcription by RNA polymerase II (IBA)

Cellular Component

cytosol (ISO)

Ino80 complex (IBA,ISO)

MLL1 complex (ISO)

NuA4 histone acetyltransferase complex (IBA,ISO)

nuclear matrix (ISO)

nucleoplasm (ISO)

nucleus (ISO)

protein-containing complex (ISO)

R2TP complex (IBA,ISO)

ribonucleoprotein complex (IDA)

Swr1 complex (IBA,ISO)

Molecular Function

3'-5' DNA helicase activity (ISO)

5'-3' DNA helicase activity (IEA)

ADP binding (IDA)

ATP binding (IDA)

ATPase binding (IPI)

DNA helicase activity (IBA,ISO)

helicase activity (IEA)

hydrolase activity (IEA)

nucleotide binding (IEA)

protein binding (IPI,ISO)

TBP-class protein binding (ISO)

TFIID-class transcription factor complex binding (IPI)

transcription coactivator activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

INO80 family mediated chromatin remodeling pathway (ISO)

Wnt signaling pathway (IEA)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal blastocyst formation (IAGP)

abnormal definitive hematopoiesis (IAGP)

abnormal hematopoietic stem cell physiology (IAGP)

absent hematopoietic stem cells (IAGP)

bone marrow failure (IAGP)

decreased body weight (IEA)

decreased bone marrow cell number (IAGP)

decreased inner cell mass proliferation (IAGP)

embryonic lethality before implantation, complete penetrance (IAGP)

pancytopenia (IAGP)

premature death (IAGP)

References

References - curated


1.	Hawley SB, etal., J Biol Chem 2001 Jan 5;276(1):179-86.
2.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	MGD and Homologene mouse data transfer
4.	MGD data from the GO Consortium
5.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6.	Pipeline to import KEGG annotations from KEGG into RGD
7.	RGD automated import pipeline
8.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	RGD automated import pipeline for gene-chemical interactions
10.	Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.

Additional References at PubMed

PMID:9843967	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:12477932	PMID:12520002	PMID:14610273	PMID:15489334	PMID:15782199	PMID:15800025	PMID:16141072
PMID:16141073	PMID:17110338	PMID:17277741	PMID:17636026	PMID:17967808	PMID:18372249	PMID:19299493	PMID:19345177	PMID:19423573	PMID:20059953	PMID:20211142	PMID:20362541
PMID:21589869	PMID:21677750	PMID:21873635	PMID:22371176	PMID:24146773	PMID:24302573	PMID:24457600	PMID:24680824	PMID:25428364	PMID:25857206	PMID:26365490	PMID:26496610
PMID:26639898	PMID:26711270	PMID:27746211	PMID:28378742	PMID:29113992	PMID:29959317	PMID:30196744	PMID:30498063	PMID:31077711	PMID:31186351	PMID:32098917	PMID:33293536

Genomics

Comparative Map Data

Ruvbl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	88,442,391 - 88,474,548 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	6	88,442,391 - 88,474,554 (+)	Ensembl
GRCm38	6	88,465,409 - 88,497,566 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	88,465,409 - 88,497,572 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	88,415,417 - 88,447,560 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	88,431,107 - 88,463,207 (+)	NCBI			mm8
Celera	6	90,403,044 - 90,439,348 (+)	NCBI		Celera
Cytogenetic Map	6	D1	NCBI

RUVBL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	3	128,064,778 - 128,153,914 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	3	128,064,611 - 128,153,914 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	3	127,783,628 - 127,872,757 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	129,282,493 - 129,325,332 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	3	129,282,500 - 129,325,340	NCBI
Celera	3	126,230,848 - 126,272,604 (-)	NCBI
Cytogenetic Map	3	q21.3	NCBI
HuRef	3	125,180,247 - 125,223,118 (-)	NCBI		HuRef
CHM1_1	3	127,746,833 - 127,835,772 (-)	NCBI		CHM1_1

Ruvbl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	120,932,486 - 120,967,400 (+)	NCBI
Rnor_6.0 Ensembl	4	120,411,991 - 120,447,455 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	4	120,411,917 - 120,447,458 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	4	185,651,851 - 185,687,385 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	122,556,857 - 122,591,769 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	122,801,337 - 122,836,249 (+)	NCBI
Celera	4	109,888,321 - 109,923,233 (+)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

Ruvbl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955429	15,598,465 - 15,633,713 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955429	15,598,465 - 15,632,290 (+)	NCBI	ChiLan1.0	ChiLan1.0

RUVBL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	3	132,486,229 - 132,528,925 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	132,486,229 - 132,528,918 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	3	125,120,524 - 125,200,859 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

RUVBL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	20	2,095,786 - 2,137,579 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	20	2,095,807 - 2,137,528 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Ruvbl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936798	559,706 - 572,710 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RUVBL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	72,200,511 - 72,248,582 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	72,196,219 - 72,246,514 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RUVBL1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	52,887,374 - 52,967,728 (+)	NCBI
ChlSab1.1 Ensembl	22	52,924,819 - 52,967,830 (+)	Ensembl

Ruvbl1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624961	427,836 - 460,887 (+)	NCBI

Position Markers

D6Mit226

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	6	88,474,359 - 88,474,505	UniSTS	GRCm38
MGSCv37	6	88,424,353 - 88,424,499	UniSTS	GRCm37
Celera	6	90,414,252 - 90,414,417	UniSTS
Cytogenetic Map	6	D1	UniSTS
cM Map	6	37.0	UniSTS
Whitehead Genetic	6	29.5	UniSTS
Whitehead_YAC	6		UniSTS

QTLs in Region (GRCm38)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
25440480	Moaq2_m	modifier of alien QTL 2 (mouse)					6	1	117500000	Mouse
26884414	Bzwq12_m	bi-zygomatic width QTL 12, 16 week (mouse)					6	3400000	139100000	Mouse
4142126	W3q3_m	weight 3 weeks QTL 3 (mouse)			Not determined			4503823	96656149	Mouse
4142361	W10q11_m	weight 10 weeks QTL 11 (mouse)			Not determined			4503823	96656149	Mouse
4142271	Egq8_m	early growth QTL 8 (mouse)			Not determined			4503823	96656149	Mouse
4142232	W6q4_m	weight 6 weeks QTL 4 (mouse)			Not determined			4503823	96656149	Mouse
1558984	Cplaq9_m	circadian period of locomotor activity 9 (mouse)			Not determined		6	38669625	92607450	Mouse
10412157	Fl1n_m	fatty liver 1 in NSY (mouse)			Not determined		6	45314059	128835032	Mouse
4142259	Tabw2_m	tally ho associated body weight 2 (mouse)			Not determined			46935985	136423692	Mouse
25314319	Histh6_m	histamine hypersensitivity 6 (mouse)					6	48720000	125360000	Mouse
25314320	Histh5_m	histamine hypersensitivity 5 (mouse)					6	48720000	148450000	Mouse
1301962	Eila2_m	ethanol induced locomotor activity 2 (mouse)			Not determined		6	48726556	125356785	Mouse
1357683	Igf1sl1_m	IGF-1 serum levels 1 (mouse)			Not determined		6	52161713	116155267	Mouse
15039373	Adip28_m	adiposity 28 (mouse)					6	56308211	90308211	Mouse
15039375	Bw41_m	body weight QTL 41 (mouse)					6	56308211	90308211	Mouse
1558977	Skmw10_m	skeletal muscle weight 10 (mouse)			Not determined		6	58447583	92447710	Mouse
10043972	Obq28_m	obesity QTL 28 (mouse)			Not determined		6	58540433	92540433	Mouse
1301740	Bwq2_m	body weight QTL 2 (mouse)			Not determined		6	60057680	94057799	Mouse
1301369	Im4_m	immunoregulatory 4 (mouse)			Not determined		6	63484738	97484905	Mouse
1300650	Bw18_m	body weight QTL 18 (mouse)			Not determined		6	66713869	100714031	Mouse
1301876	Bits2_m	bitterness sensitivity 2 (mouse)			Not determined		6	70425898	104426034	Mouse
1301813	Skl3_m	skeletal size (tail length) 3 (mouse)			Not determined		6	70425898	104426034	Mouse
1301034	Egrm2_m	early growth rate (mouse)			Not determined		6	70425898	104426034	Mouse
1302020	Bbaa20_m	B.burgdorferi-associated arthritis 20 (mouse)			Not determined		6	71322621	93464093	Mouse
1300869	Stheal5_m	soft tissue heal 5 (mouse)			Not determined		6	71575060	105575178	Mouse
1300954	Fcsa1_m	femoral cross-sectional area 1 (mouse)			Not determined		6	71981024	105981170	Mouse
1301521	Pas1c_m	pulmonary adenoma susceptibility 1c (mouse)			Not determined		6	71981024	105981170	Mouse
13506930	Recrq9_m	recombination rate in male meiosis QTL 9 (mouse)					6	73500000	134700000	Mouse
1301320	Ots1_m	ovarian teratoma susceptibility 1 (mouse)			Not determined		6	75447583	104503555	Mouse
1301571	Arrd1_m	age-related retinal degeneration 1 (mouse)			Not determined		6	75544356	92607450	Mouse
1300674	Nidd3n_m	non-insulin-dependent diabetes mellitus 3 in NSY (mouse)			Not determined		6	75544356	94225955	Mouse
10412195	Efw_m	epididymal fat weight (mouse)			Not determined		6	75544356	94225955	Mouse
10043901	Pfat5_m	predicted fat percentage 5 (mouse)			Not determined		6	75607306	109607450	Mouse
10412208	Cypr4_m	cytokine production 4 (mouse)			Not determined		6	75716503	109716697	Mouse
1357875	Pfat2_m	predicted fat percentage 2 (mouse)			Not determined		6	76463949	110464093	Mouse
14697704	Stsl4_m	Salmonella typhimurium susceptibility locus 4 (mouse)					6	77100000	90000000	Mouse
13824985	Alh1_m	amplitude of lateral head displacement 1 (mouse)					6	78000000	97000000	Mouse
4141376	Dbm1_m	diabetes modifier 1 (mouse)			Not determined		6	78629504	121115387	Mouse
14696731	Pairq1_m	P. aeruginosa infection resistance QTL 1 (mouse)					6	81500000	102200000	Mouse
10043864	T2dm4sa_m	type 2 diabetes mellitus 4 in SMXA RI mice (mouse)			Not determined		6	83713869	147052561	Mouse
11251720	Ewc4_m	ethanol withdrawal and consumption 4 (mouse)					6	84122513	118122513	Mouse
1301687	Mnic2_m	macronutrient intake (mouse)			Not determined		6	86806805	113544602	Mouse
1301744	Hdlq11_m	HDL QTL 11 (mouse)			Not determined		6	87503360	121503555	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	315
Count of miRNA genes:	248
Interacting mature miRNAs:	283
Transcripts:	ENSMUST00000032165, ENSMUST00000129035
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_019685	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC153694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC154038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF100694	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK012170	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK132783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK145062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK156078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK183435	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK186720	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK188570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK198661	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC004718	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CJ146900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000032165 ⟹ ENSMUSP00000032165

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	88,465,409 - 88,497,572 (+)	Ensembl

RefSeq Acc Id:

ENSMUST00000129035 ⟹ ENSMUSP00000117925

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38.p6 Ensembl	6	88,465,727 - 88,482,187 (+)	Ensembl

RefSeq Acc Id:

NM_019685 ⟹ NP_062659

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	6	88,442,391 - 88,474,548 (+)	NCBI
GRCm38	6	88,465,409 - 88,497,566 (+)	NCBI
MGSCv37	6	88,415,417 - 88,447,560 (+)	RGD
Celera	6	90,403,044 - 90,439,348 (+)	RGD
cM Map	6		ENTREZGENE

Sequence:

show sequence

ATATTGATAGGGGCGGGTCCAGGAGAGCGGCCTAGTAACGGCCGCGTGGTAACCCAGGCGCCTG
GCGTGCGGTAGTTCCTACCACTCCACGCAGGTTGTGTTCCTAGACACTCGGCAAAATGAAGATT
GAGGAGGTGAAGAGCACCACGAAGACGCAGCGCATCGCCTCCCACAGCCACGTGAAGGGTCTGG
GGCTGGACGAGAGCGGCCTAGCCAAGCAGGCGGCTTCGGGTCTCGTGGGCCAGGAGAACGCGAG
AGAGGCATGTGGCGTCATTGTAGAATTAATCAAAAGCAAGAAAATGGCTGGAAGAGCTGTCTTG
TTGGCGGGGCCTCCTGGAACTGGCAAGACAGCCTTGGCCCTTGCTATTGCTCAGGAGCTGGGCA
GTAAAGTCCCTTTCTGCCCGATGGTGGGTAGCGAGGTATACTCAACTGAGATCAAAAAGACAGA
GGTGCTGATGGAGAACTTCCGCAGGGCCATTGGGTTGCGGATAAAGGAGACTAAGGAGGTTTAT
GAAGGGGAGGTGACAGAGCTCACTCCCTGTGAGACAGAGAACCCCATGGGTGGGTACGGCAAAA
CTATCAGCCATGTGATCATAGGGCTCAAGACTGCTAAAGGAACCAAACAGCTGAAGCTGGACCC
CAGTATTTTTGAAAGTTTGCAGAAAGAACGAGTAGAGGCTGGAGATGTGATTTACATTGAAGCA
AATAGTGGAGCTGTGAAGAGGCAAGGCAGGTGTGACACCTATGCCACAGAGTTTGACCTTGAAG
CTGAAGAGTACGTCCCTTTGCCAAAGGGAGATGTGCACAAGAAGAAGGAAATCATACAGGATGT
GACCTTGCATGACCTGGATGTGGCTAATGCGCGGCCTCAGGGTGGGCAAGATATTCTGTCTATG
ATGGGCCAGTTGATGAAGCCAAAAAAGACAGAGATCACAGATAAACTTCGAGGGGAGATCAACA
AAGTGGTGAACAAATACATTGACCAGGGTGTGGCCGAGCTGGTCCCTGGAGTGCTTTTTGTCGA
TGAGGTCCACATGCTGGATATCGAGTGCTTTACCTACCTGCACCGAGCCCTGGAGTCCTCCATC
GCCCCCATTGTCATCTTTGCATCCAACCGAGGCAACTGTGTCATCAGGGGCACTGAGGACATCA
CTTCTCCACACGGCATCCCGTTGGATCTGCTAGACAGGGTGATGATCATCAGGACCATGCTATA
CACGCCACAGGAGATGAAGCAGATCATTAAGATCCGAGCCCAGACGGAAGGCATCAACATCAGC
GAGGAGGCGCTGAACCACCTCGGGGAGATTGGCACCAAGACCACTCTGAGGTATTCGGTGCAGC
TGCTGACCCCAGCCAACCTGCTGGCAAAGATCAATGGCAAGGACAGCATTGAGAAGGAGCACGT
GGAAGAGATCAGCGAGCTCTTCTATGACGCCAAGTCCTCTGCCAAGATTTTGGCTGACCAGCAG
GACAAGTACATGAAGTAACGTTGGGATGGAGGCGCACCCAGAGACGGACCCCACACCGTGCACA
GGGGCTCGCCTCAAGCATGCTTTGCAGTGTTACAGTTTCTTTGTAAATTATCAAACCTCCATGG
TGGTTTGGAAGGATCCCTTCCCCACCTAGCTTGTTTTCTAATAAAACTGAATAGGTTATTTTGA
TGATAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_062659	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD02877	(Get FASTA)	NCBI Sequence Viewer
	AAH04718	(Get FASTA)	NCBI Sequence Viewer
	BAE21358	(Get FASTA)	NCBI Sequence Viewer
	BAE27123	(Get FASTA)	NCBI Sequence Viewer
	BAE33576	(Get FASTA)	NCBI Sequence Viewer
	EDK99249	(Get FASTA)	NCBI Sequence Viewer
	P60122	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_062659 ⟸ NM_019685

- UniProtKB:

P60122 (UniProtKB/Swiss-Prot), Q3U1C2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAGR
AVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETK
EVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIY
IEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDI
LSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFVDEVHMLDIECFTYLHRALE
SSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGI
NISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILA
DQQDKYMK

hide sequence

RefSeq Acc Id:

ENSMUSP00000032165 ⟸ ENSMUST00000032165

RefSeq Acc Id:

ENSMUSP00000117925 ⟸ ENSMUST00000129035

Protein Domains

AAA TIP49

Promoters

RGD ID:

6839955

Promoter ID:

MM_KWN:46819

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B6

Transcripts:

OTTMUST00000058579, OTTMUST00000058580

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	6	88,415,121 - 88,415,621 (+)	MPROMDB

RGD ID:

6890372

Promoter ID:

EPDNEW_M8637

Type:

initiation region

Name:

Ruvbl1_1

Description:

Mus musculus RuvB-like protein 1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	6	88,465,442 - 88,465,502	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1928760	AgrOrtholog
Ensembl Genes	ENSMUSG00000030079	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSMUSP00000032165	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUSP00000117925	UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000032165	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSMUST00000129035	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.360	UniProtKB/TrEMBL
InterPro	AAA+_ATPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NA-bd_OB-fold	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RuvB-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RuvB-like_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RUVBL1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RUVBL2_DII	UniProtKB/TrEMBL
	TIP49_P-loop	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:56505	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1928760	ENTREZGENE
NCBI Gene	56505	ENTREZGENE
PANTHER	PTHR11093	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11093:SF6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	TIP49	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIP49_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ruvbl1	PhenoGen
SMART	AAA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50249	UniProtKB/TrEMBL
	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	D3YW60_MOUSE	UniProtKB/TrEMBL
	P60122	ENTREZGENE
	Q3U1C2	ENTREZGENE, UniProtKB/TrEMBL
	Q3UJN2_MOUSE	UniProtKB/TrEMBL
	RUVB1_MOUSE	UniProtKB/Swiss-Prot
UniProt Secondary	O35753	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

RGD Manual Annotations

Imported Annotations - KEGG (archival)