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Gene: G6pdx (glucose-6-phosphate dehydrogenase X-linked) Mus musculus
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Symbol: G6pdx
Name: glucose-6-phosphate dehydrogenase X-linked
Description: Exhibits glucose-6-phosphate dehydrogenase activity and protein homodimerization activity. Involved in several processes, including NADP biosynthetic process; erythrocyte development; and regulation of blood vessel diameter by renin-angiotensin. Predicted to localize to several cellular components, including the centriolar satellite; cytoplasmic side of plasma membrane; and cytosol. Used to study favism. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Is expressed in several structures, including adipose tissue; genitourinary system; immune system; liver; and mammary gland. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G28A; G6pd; glucose-6-phosphate 1-dehydrogenase X; Gpdx
Orthologs:
Homo sapiens (human) : G6PD (glucose-6-phosphate dehydrogenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : G6pd (glucose-6-phosphate dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pd (glucose-6-phosphate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PD (glucose-6-phosphate dehydrogenase)
Canis lupus familiaris (dog) : G6PD (glucose-6-phosphate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pd (glucose-6-phosphate dehydrogenase)
Sus scrofa (pig) : G6PD (glucose-6-phosphate dehydrogenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38X74,409,483 - 74,428,880 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X71,654,825 - 71,674,500 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,662,206 - 70,681,881 (-)NCBImm8
CeleraX65,663,679 - 65,683,364 (-)NCBICelera
Cytogenetic MapX A7.3NCBI
cM MapX38.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on G6pdx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10608
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.