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Gene: G6pdx (glucose-6-phosphate dehydrogenase X-linked) Mus musculus
Symbol: G6pdx
Name: glucose-6-phosphate dehydrogenase X-linked
Description: Exhibits glucose-6-phosphate dehydrogenase activity and protein homodimerization activity. Involved in several processes, including NADP biosynthetic process; erythrocyte development; and regulation of blood vessel diameter by renin-angiotensin. Predicted to localize to several cellular components, including the centriolar satellite; cytoplasmic side of plasma membrane; and cytosol. Used to study favism. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); cerebrovascular disease; favism; malaria (multiple); and neonatal jaundice. Is expressed in several structures, including adipose tissue; genitourinary system; immune system; liver; and mammary gland. Orthologous to human G6PD (glucose-6-phosphate dehydrogenase); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - oxidative phase; ribose 5-phosphate isomerase deficiency pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 1H-pyrazole.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: G28A; G6pd; glucose-6-phosphate 1-dehydrogenase X; Gpdx
Homo sapiens (human) : G6PD (glucose-6-phosphate dehydrogenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : G6pd (glucose-6-phosphate dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : G6pd (glucose-6-phosphate dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : G6PD (glucose-6-phosphate dehydrogenase)
Canis lupus familiaris (dog) : G6PD (glucose-6-phosphate dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : G6pd (glucose-6-phosphate dehydrogenase)
Sus scrofa (pig) : G6PD (glucose-6-phosphate dehydrogenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38X74,409,483 - 74,428,880 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X71,654,825 - 71,674,500 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,662,206 - 70,681,881 (-)NCBImm8
CeleraX65,663,679 - 65,683,364 (-)NCBICelera
Cytogenetic MapX A7.3NCBI
cM MapX38.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on G6pdx
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10608
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.