Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ephx1 (epoxide hydrolase 1, microsomal) Mus musculus
Analyze
Symbol: Ephx1
Name: epoxide hydrolase 1, microsomal
Description: Predicted to have cis-stilbene-oxide hydrolase activity; enzyme binding activity; and epoxide hydrolase activity. Involved in cellular aromatic compound metabolic process and response to organic cyclic compound. Predicted to localize to the intracellular membrane-bounded organelle and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Is expressed in several structures, including brain ventricle and choroid plexus; cranial ganglion; integumental system; nose; and salivary gland. Orthologous to human EPHX1 (epoxide hydrolase 1); PARTICIPATES IN carbamazepine pharmacokinetics pathway; phenytoin pharmacodynamics pathway; bile acid transport pathway; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; (9R,10S)-9,10-epoxy-9,10-dihydrophenanthrene; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI195553; EH; Eph-1; Eph1; epoxide hydratase; epoxide hydrolase 1; Epxh1; mEH; microsomal epoxide hydrolase
Orthologs:
Homo sapiens (human) : EPHX1 (epoxide hydrolase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ephx1 (epoxide hydrolase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ephx1 (epoxide hydrolase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHX1 (epoxide hydrolase 1)
Canis lupus familiaris (dog) : EPHX1 (epoxide hydrolase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ephx1 (epoxide hydrolase 1)
Sus scrofa (pig) : EPHX1 (epoxide hydrolase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381180,989,556 - 181,017,569 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371182,919,687 - 182,947,626 (-)NCBIGRCm37mm9NCBIm37
MGSCv361182,826,231 - 182,854,170 (-)NCBImm8
Celera1188,055,356 - 188,083,565 (-)NCBICelera
Cytogenetic Map1 H4NCBI
cM Map184.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ephx1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10529
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.