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Gene: Dio1 (deiodinase, iodothyronine, type I) Mus musculus
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Symbol: Dio1
Name: deiodinase, iodothyronine, type I
Description: Exhibits selenium binding activity and thyroxine 5'-deiodinase activity. Predicted to be involved in thyroid hormone metabolic process. Predicted to localize to the endoplasmic reticulum and integral component of membrane. Is expressed in gut; liver and biliary system; and metanephros. Orthologous to human DIO1 (iodothyronine deiodinase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 5DI; D1; DIOI; ITDI1; MGC107659; TXDI1; type 1 DI; type I iodothyronine deiodinase; type-I 5'-deiodinase
Orthologs:
Homo sapiens (human) : DIO1 (iodothyronine deiodinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dio1 (iodothyronine deiodinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dio1 (iodothyronine deiodinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DIO1 (iodothyronine deiodinase 1)
Canis lupus familiaris (dog) : DIO1 (iodothyronine deiodinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dio1 (iodothyronine deiodinase 1)
Sus scrofa (pig) : DIO1 (iodothyronine deiodinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384107,291,465 - 107,307,168 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374106,964,070 - 106,979,748 (-)NCBIGRCm37mm9NCBIm37
MGSCv364106,789,399 - 106,805,075 (-)NCBImm8
Celera4105,641,752 - 105,661,893 (-)NCBICelera
Cytogenetic Map4 C7NCBI
cM Map450.18NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dio1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10474
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.