Myl1 (myosin, light polypeptide 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Myl1 (myosin, light polypeptide 1) Mus musculus
Analyze
Symbol: Myl1
Name: myosin, light polypeptide 1
RGD ID: 1557603
MGI Page MGI
Description: Predicted to be a structural constituent of muscle. Predicted to be involved in cardiac muscle contraction. Predicted to be located in myofibril. Predicted to be part of myosin II complex. Predicted to be active in contractile muscle fiber. Is expressed in several structures, including diaphragm; embryo mesenchyme; eye; heart; and skeletal musculature. Human ortholog(s) of this gene implicated in congenital myopathy 14. Orthologous to human MYL1 (myosin light chain 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A1 catalytic; A2 catalytic; AI325107; atrial, embryonic; D12Mgi4; MLC1; MLC1/MLC3; MLC1f; MLC1F/MLC3F; MLC3; MLC3f; Myl; Mylf; myosin light chain 1/3, skeletal muscle isoform; myosin light chain A1/A2; myosin light chain alkali 1/2; myosin light chain, alkali, fast skeletal muscle; myosin, light polypeptide 1, alkali; myosin, light polypeptide 1, alkali, atrial, embryonic; myosin, light polypeptide 4, alkali; myosin, light polypeptide 4, alkali, atrial, embryonic
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Mylf-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39166,963,454 - 66,987,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl166,963,454 - 66,984,563 (-)EnsemblGRCm39 Ensembl
GRCm38166,924,295 - 66,947,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl166,924,295 - 66,945,404 (-)EnsemblGRCm38mm10GRCm38
MGSCv37166,970,869 - 66,991,630 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36166,857,506 - 66,878,240 (-)NCBIMGSCv36mm8
Celera167,442,110 - 67,462,688 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mousecongenital myopathy 14  ISOMYL1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 and PMID:30215711
Myl1MouseNeurodevelopmental Disorders  ISOMYL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Myl1Mouseprimary pulmonary hypertension  ISOMYL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary pulmonary hypertensionClinVarPMID:28492532 and PMID:31727138
Myl1Mousetrichorhinophalangeal syndrome type I  ISOMYL1 (Homo sapiens)8554872ClinVar Annotator: match by term: Trichorhinophalangeal dysplasia type IClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1MouseHeart Injuries  ISOMYL1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19854236
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mousecongenital myopathy 14  ISOMYL1 (Homo sapiens)7240710 OMIM 

1 to 20 of 94 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mouse(R)-noradrenaline increases phosphorylationISOMYL1 (Homo sapiens)6480464Norepinephrine results in increased phosphorylation of MYL1 proteinCTDPMID:37963515
Myl1Mouse(R)-noradrenaline multiple interactionsISOMYL1 (Homo sapiens)6480464PRKD1 protein affects the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein]CTDPMID:37963515
Myl1Mouse(R)-noradrenaline multiple interactionsISOMyl1 (Rattus norvegicus)6480464chelerythrine inhibits the reaction [Norepinephrine results in increased phosphorylation of MYL1 protein] more ...CTDPMID:37963515
Myl1Mouse(R)-noradrenaline increases phosphorylationISOMyl1 (Rattus norvegicus)6480464Norepinephrine results in increased phosphorylation of MYL1 proteinCTDPMID:37963515
Myl1Mouse1,2-dimethylhydrazine multiple interactionsEXP 6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of MYL1 mRNA]CTDPMID:22206623
Myl1Mouse1,2-dimethylhydrazine increases expressionEXP 64804641 and 2-Dimethylhydrazine results in increased expression of MYL1 mRNACTDPMID:22206623
Myl1Mouse17alpha-ethynylestradiol affects expressionEXP 6480464Ethinyl Estradiol affects the expression of MYL1 mRNACTDPMID:17555576
Myl1Mouse17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of MYL1 mRNACTDPMID:17942748
Myl1Mouse17alpha-ethynylestradiol multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MYL1 mRNACTDPMID:17942748
Myl1Mouse17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of MYL1 mRNACTDPMID:19484750
Myl1Mouse2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MYL1 mRNACTDPMID:17942748
Myl1Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOMyl1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of MYL1 mRNACTDPMID:32109520
Myl1Mouse3,3',4,4',5-pentachlorobiphenyl increases expressionISOMyl1 (Rattus norvegicus)64804643 more ...CTDPMID:32119087
Myl1Mouse4,4'-sulfonyldiphenol increases expressionEXP 6480464bisphenol S results in increased expression of MYL1 mRNACTDPMID:30951980
Myl1Mouse4,4'-sulfonyldiphenol affects methylationEXP 6480464bisphenol S affects the methylation of MYL1 geneCTDPMID:31683443
Myl1Mouse4,4'-sulfonyldiphenol decreases expressionEXP 6480464bisphenol S results in decreased expression of MYL1 mRNACTDPMID:34850234
Myl1Mouse6-propyl-2-thiouracil increases expressionISOMyl1 (Rattus norvegicus)6480464Propylthiouracil results in increased expression of MYL1 mRNACTDPMID:24780913
Myl1Mouseacrylamide decreases expressionISOMyl1 (Rattus norvegicus)6480464Acrylamide results in decreased expression of MYL1 mRNACTDPMID:22197712 and PMID:28606764
Myl1Mouseaflatoxin B1 decreases methylationISOMYL1 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of MYL1 geneCTDPMID:27153756
Myl1Mousealpha-Zearalanol decreases expressionISOMyl1 (Rattus norvegicus)6480464Zeranol results in decreased expression of MYL1 mRNACTDPMID:35163327

1 to 20 of 94 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mousecardiac muscle contraction  ISOMyl1 (Rattus norvegicus)9068941 RGDPMID:9409484 and REF_RGD_ID:1600167
Myl1Mousecardiac muscle contraction involved_inISOMyl1 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Myl1Mousemuscle contraction involved_inISOUniProtKB:P059762290270 GO_CentralGO_REF:0000119
Myl1Mousemuscle contraction involved_inIEAUniProtKB:P05976 and ensembl:ENSP000003072802290270 EnsemblGO_REF:0000107

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mousecontractile muscle fiber is_active_inIBAPANTHER:PTN002746046 more ...2290270 GO_CentralGO_REF:0000033
Myl1Mousecontractile muscle fiber located_inISOMyl1 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Myl1Mousecontractile muscle fiber  ISOMyl1 (Rattus norvegicus)9068941 RGDPMID:9409484 and REF_RGD_ID:1600167
Myl1Mousemyofibril located_inISOUniProtKB:P059762290270 GO_CentralGO_REF:0000119
Myl1Mousemyofibril located_inIEAUniProtKB:P05976 and ensembl:ENSP000003072802290270 EnsemblGO_REF:0000107
Myl1Mousemyosin complex part_ofIEAUniProtKB-KW:KW-05182290270 UniProtGO_REF:0000043
Myl1Mousemyosin II complex part_ofIBAPANTHER:PTN000549249 more ...2290270 GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mousecalcium ion binding enablesIEAInterPro:IPR0020482290270 InterProGO_REF:0000002
Myl1Mousestructural constituent of muscle enablesISSUniProtKB:P059762290270 UniProtGO_REF:0000024
Myl1Mousestructural constituent of muscle enablesISOUniProtKB:P059762290270 GO_CentralGO_REF:0000119

1 to 20 of 77 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Myl1Mouseabnormal cellular respiration  IAGP 5509061 MGIPMID:28683291
Myl1Mouseabnormal cholesterol homeostasis  IAGP 5509061 MGIPMID:29898916
Myl1Mouseabnormal extraembryonic endoderm formation  IAGP 5509061 MGIPMID:11884037
Myl1Mouseabnormal lipid homeostasis  IAGP 5509061 MGIPMID:30989113
Myl1Mouseabnormal locomotor coordination  IAGP 5509061 MGIPMID:17626887
Myl1Mouseabnormal mitochondrial crista morphology  IAGP 5509061 MGIPMID:29898916
Myl1Mouseabnormal motor coordination/balance  IAGP 5509061 MGIPMID:29898916
Myl1Mouseabnormal muscle fiber mitochondrial morphology  IAGP 5509061 MGIPMID:29898916
Myl1Mouseabnormal muscle fiber morphology  IAGP 5509061 MGIPMID:29898916
Myl1Mouseabnormal muscle physiology  IAGP 5509061 MGIPMID:28475869
Myl1Mouseabnormal muscle spindle morphology  IAGP 5509061 MGIPMID:17626887
Myl1Mouseabnormal oxidative phosphorylation  IAGP 5509061 MGIPMID:29898916
Myl1Mouseabnormal respiratory electron transport chain  IAGP 5509061 MGIPMID:12417746
Myl1Mouseabnormal response to exercise  IAGP 5509061 MGIPMID:28683291
Myl1Mouseabnormal skeletal muscle morphology  IAGP 5509061 MGIPMID:16103131
Myl1Mouseabnormal skeletal muscle morphology  IAGP 5509061 MGIPMID:24713655
Myl1Mouseabnormal visceral yolk sac cavity morphology  IAGP 5509061 MGIPMID:11884037
Myl1Mouseabsent mesoderm  IAGP 5509061 MGIPMID:11884037
Myl1Mouseataxia  IAGP 5509061 MGIPMID:17626887
Myl1Mousebradykinesia  IAGP 5509061 MGIPMID:12417746
1 to 20 of 77 rows

#
Reference Title
Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
1 to 10 of 18 rows
PMID:1581633   PMID:1685142   PMID:1685480   PMID:1901785   PMID:1962752   PMID:1970800   PMID:2025291   PMID:2201580   PMID:2211821   PMID:2534378   PMID:2696048   PMID:2892781  
PMID:2983233   PMID:3022377   PMID:3194193   PMID:3242494   PMID:3865381   PMID:4942892   PMID:6091905   PMID:6283523   PMID:7588068   PMID:7720708   PMID:7721942   PMID:7787235  
PMID:7828830   PMID:8136524   PMID:8207020   PMID:8288247   PMID:8404542   PMID:8587605   PMID:8668209   PMID:8751373   PMID:8754853   PMID:8950513   PMID:9242416   PMID:9489771  
PMID:9689582   PMID:10349636   PMID:10686620   PMID:11042159   PMID:11076861   PMID:11090542   PMID:11884037   PMID:12417746   PMID:12466851   PMID:12477932   PMID:12819125   PMID:15082723  
PMID:15499557   PMID:16103131   PMID:16141072   PMID:16141073   PMID:16494860   PMID:16996481   PMID:17289669   PMID:17380205   PMID:17626887   PMID:18054315   PMID:18062958   PMID:18554416  
PMID:18694957   PMID:18753145   PMID:18945718   PMID:18957633   PMID:18973680   PMID:19506036   PMID:19661286   PMID:19945408   PMID:19962975   PMID:20065166   PMID:20403324   PMID:20625437  
PMID:20814569   PMID:20861693   PMID:21037586   PMID:21109195   PMID:21253590   PMID:21267068   PMID:21873635   PMID:21946846   PMID:22190261   PMID:22267199   PMID:22522309   PMID:22673621  
PMID:23202295   PMID:23369715   PMID:23504871   PMID:23516375   PMID:23630012   PMID:23734214   PMID:23892084   PMID:24076600   PMID:24145720   PMID:24154528   PMID:24227653   PMID:24487027  
PMID:24567902   PMID:24632224   PMID:24662047   PMID:24713655   PMID:24844572   PMID:24876160   PMID:24938781   PMID:25172430   PMID:25176656   PMID:25380823   PMID:25496993   PMID:25794679  
PMID:25858807   PMID:25982555   PMID:26011449   PMID:26056297   PMID:26214036   PMID:26306597   PMID:26331883   PMID:26374844   PMID:26411342   PMID:26446156   PMID:26603188   PMID:26629406  
1 to 10 of 18 rows



Myl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39166,963,454 - 66,987,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl166,963,454 - 66,984,563 (-)EnsemblGRCm39 Ensembl
GRCm38166,924,295 - 66,947,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl166,924,295 - 66,945,404 (-)EnsemblGRCm38mm10GRCm38
MGSCv37166,970,869 - 66,991,630 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36166,857,506 - 66,878,240 (-)NCBIMGSCv36mm8
Celera167,442,110 - 67,462,688 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.71NCBI
MYL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382210,290,150 - 210,315,174 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2210,290,150 - 210,315,174 (-)EnsemblGRCh38hg38GRCh38
GRCh372211,154,874 - 211,179,898 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362210,863,113 - 210,888,140 (-)NCBINCBI36Build 36hg18NCBI36
Build 342210,980,382 - 210,993,845NCBI
Celera2204,922,877 - 204,947,923 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2203,000,114 - 203,025,138 (-)NCBIHuRef
CHM1_12211,160,958 - 211,186,022 (-)NCBICHM1_1
T2T-CHM13v2.02210,770,853 - 210,795,901 (-)NCBIT2T-CHM13v2.0
Myl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2968,437,514 - 68,458,256 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,437,517 - 68,458,261 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx976,926,694 - 76,947,188 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0982,055,627 - 82,076,116 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0980,461,970 - 80,482,459 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0973,937,820 - 73,958,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl973,937,823 - 73,958,480 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0973,349,226 - 73,369,886 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4965,717,097 - 65,737,576 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera965,916,653 - 65,937,125 (-)NCBICelera
Cytogenetic Map9q32NCBI
Myl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554575,146,633 - 5,168,356 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554575,147,443 - 5,167,587 (+)NCBIChiLan1.0ChiLan1.0
MYL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213112,913,613 - 112,938,932 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B112,928,593 - 112,953,912 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B97,548,013 - 97,573,336 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B215,940,808 - 215,974,852 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B215,950,087 - 215,974,852 (-)Ensemblpanpan1.1panPan2
MYL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13718,143,644 - 18,168,208 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3718,143,673 - 18,168,187 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3719,024,436 - 19,048,975 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03718,081,858 - 18,106,400 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3718,050,944 - 18,106,386 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13718,034,367 - 18,058,915 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03717,996,703 - 18,021,269 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03718,011,588 - 18,036,161 (-)NCBIUU_Cfam_GSD_1.0
Myl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303166,612,434 - 166,632,566 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365865,993,098 - 6,013,994 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365865,993,177 - 6,013,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15113,036,228 - 113,063,321 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115113,038,083 - 113,051,315 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215124,861,888 - 124,875,123 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap15q23-q26NCBI
MYL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11096,015,186 - 96,041,862 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1096,015,034 - 96,029,160 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040103,314,602 - 103,340,346 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247655,883,524 - 5,904,179 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247655,883,908 - 5,903,759 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Myl1
1225 total Variants

Predicted Target Of
Summary Value
Count of predictions:565
Count of miRNA genes:391
Interacting mature miRNAs:449
Transcripts:ENSMUST00000027151, ENSMUST00000119429, ENSMUST00000120415, ENSMUST00000150542, ENSMUST00000151328, ENSMUST00000160100
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 51 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
11039528Ccc3_mcolitis susceptibility in the Collaborative Cross 3 (mouse)13680142195051546Mouse
4142015Idd5.3_minsulin dependent diabetes susceptibility 5.3 (mouse)Not determined6652316270077076Mouse
12910788Pwgrq9_mpost-weaning growth rate QTL 9 (mouse)14086800867270256Mouse
18182931Metl1_mmetabolite locus 1, pyridoxate (mouse)14127539975275399Mouse
12910786Pwgrq10_mpost-weaning growth rate QTL 10 (mouse)14086800867270256Mouse
10412185Hcs9_mhepatocarcinogenesis susceptibility 9 (mouse)Not determined163854690189303617Mouse
13824984Twq5_mtestis weight QTL 5 (mouse)13069992184732197Mouse
1357721Sle17_msystematic lupus erythematosus susceptibility 17 (mouse)Not determined139132808126445310Mouse
1357824Estoq4_membryo survival total QTL 4 (mouse)Not determined13476013873976915Mouse
14746998Mancz1_mmandible centroid size 1 (mouse)15794135191941351Mouse

1 to 10 of 51 rows
RH129698  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38166,924,344 - 66,924,533UniSTSGRCm38
MGSCv37166,970,918 - 66,971,107UniSTSGRCm37
Cytogenetic Map1C3UniSTS
cM Map134.1UniSTS
AI325107  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812101,221,907 - 101,221,987UniSTSGRCm38
MGSCv3712102,460,117 - 102,460,197UniSTSGRCm37
Celera12102,450,500 - 102,450,580UniSTS
Cytogenetic Map12EUniSTS
Cytogenetic Map1C3UniSTS
cM Map134.1UniSTS
Whitehead/MRC_RH12934.83UniSTS
D1Mit21.1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38166,946,344 - 66,946,456UniSTSGRCm38
MGSCv37166,992,918 - 66,993,030UniSTSGRCm37
Celera167,463,982 - 67,464,094UniSTS
Cytogenetic Map1C3UniSTS
cM Map132.8UniSTS
cM Map1 UniSTS
Whitehead Genetic134.2306UniSTS
Whitehead_YAC1 UniSTS
Mylf  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1C3UniSTS
cM Map134.1UniSTS
D1Mit21  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38166,946,183 - 66,946,425UniSTSGRCm38
MGSCv37166,992,757 - 66,992,999UniSTSGRCm37
Celera167,463,815 - 67,464,063UniSTS
Cytogenetic Map1C3UniSTS
cM Map132.8UniSTS
Whitehead Genetic132.8UniSTS






1 to 22 of 22 rows
RefSeq Transcripts NM_001113387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001420334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_021285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011238451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC124389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC133187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH002039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK009938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY785713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CU407305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K02242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W48198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W87050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X12973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X13130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 22 of 22 rows

Ensembl Acc Id: ENSMUST00000027151   ⟹   ENSMUSP00000027151
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,963,454 - 66,984,302 (-)Ensembl
GRCm38.p6 Ensembl166,924,295 - 66,945,143 (-)Ensembl
Ensembl Acc Id: ENSMUST00000119429   ⟹   ENSMUSP00000112861
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,963,457 - 66,974,513 (-)Ensembl
GRCm38.p6 Ensembl166,924,298 - 66,935,354 (-)Ensembl
Ensembl Acc Id: ENSMUST00000120415   ⟹   ENSMUSP00000112880
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,965,225 - 66,974,492 (-)Ensembl
GRCm38.p6 Ensembl166,926,066 - 66,935,333 (-)Ensembl
Ensembl Acc Id: ENSMUST00000150542
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,964,182 - 66,974,509 (-)Ensembl
GRCm38.p6 Ensembl166,925,023 - 66,935,350 (-)Ensembl
Ensembl Acc Id: ENSMUST00000151328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,983,622 - 66,984,563 (-)Ensembl
GRCm38.p6 Ensembl166,944,463 - 66,945,404 (-)Ensembl
Ensembl Acc Id: ENSMUST00000160100   ⟹   ENSMUSP00000125748
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,965,781 - 66,984,543 (-)Ensembl
GRCm38.p6 Ensembl166,926,622 - 66,945,384 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186202   ⟹   ENSMUSP00000140834
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,963,454 - 66,974,796 (-)Ensembl
GRCm38.p6 Ensembl166,924,295 - 66,935,637 (-)Ensembl
Ensembl Acc Id: ENSMUST00000186346
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl166,969,351 - 66,973,857 (-)Ensembl
GRCm38.p6 Ensembl166,930,192 - 66,934,698 (-)Ensembl
RefSeq Acc Id: NM_001113387   ⟹   NP_001106858
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,974,507 (-)NCBI
GRCm38166,924,295 - 66,935,366 (-)NCBI
MGSCv37166,970,869 - 66,991,630 (-)RGD
Celera167,442,110 - 67,462,688 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001420333   ⟹   NP_001407262
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,984,637 (-)NCBI
RefSeq Acc Id: NM_001420334   ⟹   NP_001407263
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,974,507 (-)NCBI
RefSeq Acc Id: NM_021285   ⟹   NP_067260
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,984,189 (-)NCBI
GRCm38166,924,295 - 66,945,056 (-)NCBI
MGSCv37166,970,869 - 66,991,630 (-)RGD
Celera167,442,110 - 67,462,688 (-)RGD
cM Map1 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011238451   ⟹   XP_011236753
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,965,225 - 66,974,541 (-)NCBI
GRCm38166,926,066 - 66,935,407 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162616   ⟹   XP_036018509
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,987,091 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162618   ⟹   XP_036018511
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39166,963,454 - 66,987,091 (-)NCBI
Sequence:
1 to 5 of 12 rows
1 to 5 of 12 rows
RefSeq Acc Id: NP_067260   ⟸   NM_021285
- Peptide Label: isoform 1f
- UniProtKB: P05978 (UniProtKB/Swiss-Prot),   P05977 (UniProtKB/Swiss-Prot),   Q545T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106858   ⟸   NM_001113387
- Peptide Label: isoform 3f
- UniProtKB: Q545G5 (UniProtKB/TrEMBL),   Q6PCW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011236753   ⟸   XM_011238451
- Peptide Label: isoform X2
- UniProtKB: E9PWG4 (UniProtKB/TrEMBL),   Q6PCW9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000027151   ⟸   ENSMUST00000027151
Ensembl Acc Id: ENSMUSP00000112861   ⟸   ENSMUST00000119429
EF-hand

Name Modeler Protein Id AA Range Protein Structure
AF-P05977-F1-model_v2 AlphaFold P05977 1-188 view protein structure

RGD ID:6873982
Promoter ID:EPDNEW_M442
Type:multiple initiation site
Name:Myl1_1
Description:Mus musculus myosin, light polypeptide 1 , transcript variant3f, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M443  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38166,935,348 - 66,935,408EPDNEW
RGD ID:6873984
Promoter ID:EPDNEW_M443
Type:initiation region
Name:Myl1_2
Description:Mus musculus myosin, light polypeptide 1 , transcript variant3f, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M442  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38166,945,030 - 66,945,090EPDNEW


1 to 27 of 27 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000061816 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000027151 ENTREZGENE
  ENSMUST00000027151.12 UniProtKB/Swiss-Prot
  ENSMUST00000119429 ENTREZGENE
  ENSMUST00000119429.8 UniProtKB/Swiss-Prot
  ENSMUST00000120415 ENTREZGENE
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot
InterPro Ca-Reg_Muscle_Contr_Cell_Proc UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
KEGG Report mmu:17901 UniProtKB/Swiss-Prot
MGD MGI:97269 ENTREZGENE
NCBI Gene 17901 ENTREZGENE
PANTHER MYOSIN LIGHT CHAIN 1, 3 UniProtKB/Swiss-Prot
  MYOSIN LIGHT CHAIN 1/3, SKELETAL MUSCLE ISOFORM UniProtKB/Swiss-Prot
PhenoGen Myl1 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
UniProt A0A087WRZ7_MOUSE UniProtKB/TrEMBL
  E0CZ30_MOUSE UniProtKB/TrEMBL
  E9PWG4 ENTREZGENE, UniProtKB/TrEMBL
  MYL1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  P05978 ENTREZGENE
  Q545G5 ENTREZGENE, UniProtKB/TrEMBL
  Q545T7 ENTREZGENE, UniProtKB/TrEMBL
  Q6PCW9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P05978 UniProtKB/Swiss-Prot
1 to 27 of 27 rows