Mmp14 (matrix metallopeptidase 14 (membrane-inserted)) - Rat Genome Database

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Gene: Mmp14 (matrix metallopeptidase 14 (membrane-inserted)) Mus musculus
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Symbol: Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
RGD ID: 734119
MGI Page MGI
Description: Enables metalloendopeptidase activity. Involved in several processes, including negative regulation of Notch signaling pathway; positive regulation of cell differentiation; and positive regulation of macrophage migration. Acts upstream of or within several processes, including chondrocyte proliferation; collagen catabolic process; and skeletal system morphogenesis. Predicted to be located in several cellular components, including cytosol; intermediate filament cytoskeleton; and macropinosome. Predicted to be active in extracellular space and plasma membrane. Predicted to colocalize with cytoplasm. Is expressed in several structures, including embryo mesenchyme; exocrine system; genitourinary system; heart; and musculoskeletal system. Used to study rheumatoid arthritis. Human ortholog(s) of this gene implicated in Winchester syndrome; esophagus adenocarcinoma; and myocardial infarction. Orthologous to human MMP14 (matrix metallopeptidase 14).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AI325305; matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase-14; Membrane type 1-MMP; membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-14; MMP-X1; MT-MMP 1; MT-MMP-1; MT1-MM; MT1-MMP; MT1MMP; MTMMP1; sa; sabe; type 1 matrix metalloprotease 14
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,669,055 - 54,679,913 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,669,069 - 54,682,821 (+)EnsemblGRCm39 Ensembl
GRCm381454,431,598 - 54,442,456 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,431,612 - 54,445,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371455,050,441 - 55,060,095 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,385,824 - 53,395,458 (+)NCBIMGSCv36mm8
Celera1452,223,646 - 52,233,174 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
Mmp14Mouseabdominal aortic aneurysm  ISOMmp14 (Rattus norvegicus)1582579 RGD 
Mmp14Mouseabdominal aortic aneurysm  ISOMMP14 (Homo sapiens)1582584 RGD 
Mmp14Mouseanti-basement membrane glomerulonephritis  ISOMmp14 (Rattus norvegicus)2314954mRNA:increased expression:kidney and macrophageRGD 
Mmp14Mousearteriosclerosis  IEP 1582580 RGD 
Mmp14Mousebrain infarction  ISOMmp14 (Rattus norvegicus)329845556mRNA:increased expression:brain (rat)RGD 
Mmp14Mousebrain ischemia  ISOMmp14 (Rattus norvegicus)1582577 RGD 
Mmp14Mousebreast carcinoma disease_progressionISOMMP14 (Homo sapiens)2314951 RGD 
Mmp14Mousecarotid stenosis  IAGP 1582575 RGD 
Mmp14MouseChlamydophila Infections  IEP 1582580 RGD 
Mmp14Mousecongestive heart failure disease_progressionISOMmp14 (Rattus norvegicus)1582587protein:increased expression:left ventricle (rat)RGD 
Mmp14Mousediabetic angiopathy  ISOMMP14 (Homo sapiens)1582581 RGD 
Mmp14Mousedilated cardiomyopathy  IDA 1582576 RGD 
Mmp14MouseEmbolism  ISOMMP14 (Homo sapiens)1582578 RGD 
Mmp14Mouseesophagus adenocarcinoma onsetISOMMP14 (Homo sapiens)126925218DNA:SNP:5'utr: (rs2236302) (human)RGD 
Mmp14Mouseesophagus squamous cell carcinoma  ISOMMP14 (Homo sapiens)152600903protein:increased expression: esophagusRGD 
Mmp14MouseIgA glomerulonephritis  ISOMmp14 (Rattus norvegicus)2314955mRNA:increased expression:glomerulusRGD 
Mmp14Mouseintracranial aneurysm  ISOMMP14 (Homo sapiens)1582590 RGD 
Mmp14Mouseischemia  ISOMmp14 (Rattus norvegicus)1582563 RGD 
Mmp14MouseMarfan syndrome  ISOMMP14 (Homo sapiens)1582351associated with thoracic aortic aneurysm and protein:increased expression:aorta (human)RGD 
Mmp14Mousemyocardial infarction  ISOMMP14 (Homo sapiens)1582569 RGD 
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Mmp14MouseBrain-Lung-Thyroid Syndrome  ISOMMP14 (Homo sapiens)8554872ClinVar Annotator: match by term: Brain-lung-thyroid syndromeClinVarPMID:25741868
Mmp14Mousegenetic disease  ISOMMP14 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
Mmp14Mouselysinuric protein intolerance  ISOMMP14 (Homo sapiens)8554872ClinVar Annotator: match by term: Lysinuric protein intoleranceClinVarPMID:28492532
Mmp14MouseSpecific Granule Deficiency  ISOMMP14 (Homo sapiens)8554872ClinVar Annotator: match by term: Specific granule deficiencyClinVarPMID:28492532
Mmp14MouseWinchester syndrome  ISOMMP14 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17480005 more ...
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Mmp14Mouseabdominal aortic aneurysm  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19010778
Mmp14Mouseadenocarcinoma  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21472143
Mmp14MouseBreast Neoplasms  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24014025
Mmp14Mousechronic obstructive pulmonary disease  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19661247
Mmp14MouseEsophageal Neoplasms  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21472143
Mmp14MouseFamilial Prostate Cancer  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:29892016
Mmp14Mousehepatocellular carcinoma  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:33010264
Mmp14MouseLiver Neoplasms  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:33010264
Mmp14MouseNeoplasm Invasiveness  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:24014025
Mmp14MouseNeoplastic Cell Transformation  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23804419
Mmp14MouseWinchester syndrome  ISOMMP14 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
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Mmp14Mouserheumatoid arthritis  IAGP 13592920OMIM:180300MouseDO 
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Mmp14MouseWinchester syndrome  ISOMMP14 (Homo sapiens)7240710 OMIM 

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Mmp14Mouse1,2-dichloroethane increases expressionEXP 6480464ethylene dichloride results in increased expression of MMP14 mRNACTDPMID:28189721 and PMID:28960355
Mmp14Mouse1,2-dimethylhydrazine increases expressionEXP 64804641 and 2-Dimethylhydrazine results in increased expression of MMP14 mRNACTDPMID:22206623
Mmp14Mouse1,2-dimethylhydrazine multiple interactionsEXP 6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of MMP14 mRNA]CTDPMID:22206623
Mmp14Mouse1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of MMP14 mRNACTDPMID:15913567
Mmp14Mouse1-naphthyl isothiocyanate multiple interactionsEXP 6480464O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1 and 2-diolate inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of MMP14 mRNA]CTDPMID:15913567
Mmp14Mouse17alpha-ethynylestradiol increases expressionISOMmp14 (Rattus norvegicus)6480464Ethinyl Estradiol results in increased expression of MMP14 mRNACTDPMID:15576828
Mmp14Mouse17beta-estradiol multiple interactionsISOMMP14 (Homo sapiens)6480464[Estradiol co-treated with Progesterone] results in increased expression of MMP14 protein more ...CTDPMID:17404688 more ...
Mmp14Mouse17beta-estradiol increases expressionISOMMP14 (Homo sapiens)6480464Estradiol results in increased expression of MMP14 mRNA and Estradiol results in increased expression of MMP14 proteinCTDPMID:18829229
Mmp14Mouse17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of MMP14 mRNACTDPMID:19484750 and PMID:39298647
Mmp14Mouse17beta-estradiol affects expressionISOMMP14 (Homo sapiens)6480464Estradiol affects the expression of MMP14 mRNACTDPMID:22574217
Mmp14Mouse2,3,4,7,8-Pentachlorodibenzofuran decreases expressionISOMmp14 (Rattus norvegicus)64804642 more ...CTDPMID:21724226
Mmp14Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of MMP14 mRNACTDPMID:21570461 and PMID:24058054
Mmp14Mouse2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOMmp14 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of MMP14 mRNACTDPMID:33387578
Mmp14Mouse2,3,7,8-tetrachlorodibenzodioxine affects expressionISOMmp14 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin affects the expression of MMP14 mRNACTDPMID:34747641
Mmp14Mouse2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of MMP14 mRNACTDPMID:16120747
Mmp14Mouse2,4,6-trinitrobenzenesulfonic acid multiple interactionsEXP 6480464Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNA]CTDPMID:18200517
Mmp14Mouse2,4,6-trinitrobenzenesulfonic acid increases expressionEXP 6480464Trinitrobenzenesulfonic Acid results in increased expression of MMP14 mRNACTDPMID:18200517
Mmp14Mouse2,4-dinitrotoluene affects expressionISOMmp14 (Rattus norvegicus)64804642 and 4-dinitrotoluene affects the expression of MMP14 mRNACTDPMID:21346803
Mmp14Mouse2-butoxyethanol increases expressionEXP 6480464n-butoxyethanol results in increased expression of MMP14 mRNACTDPMID:19812364
Mmp14Mouse2-hydroxypropanoic acid increases expressionISOMMP14 (Homo sapiens)6480464Lactic Acid results in increased expression of MMP14 mRNACTDPMID:30851411

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Biological Process
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Mmp14Mouseangiogenesis involved_inIEAUniProtKB:Q10739 and ensembl:ENSRNOP000000654342290270 EnsemblGO_REF:0000107
Mmp14Mouseangiogenesis  ISOMmp14 (Rattus norvegicus)9068941 RGDPMID:14766216 and REF_RGD_ID:1582561
Mmp14Mouseastrocyte cell migration involved_inIEAUniProtKB:Q10739 and ensembl:ENSRNOP000000654342290270 EnsemblGO_REF:0000107
Mmp14Mouseastrocyte cell migration  ISOMmp14 (Rattus norvegicus)9068941 RGDPMID:16265672 and REF_RGD_ID:1582598
Mmp14Mousebone development acts_upstream_of_or_withinIGIMGI:12761072290270 PMID:18022611MGIPMID:18022611
Mmp14Mousebranching morphogenesis of an epithelial tube acts_upstream_of_or_withinIMPMGI:23862462290270 PMID:15572153MGIPMID:15572153
Mmp14Mousecell migration acts_upstream_of_or_withinIMPMGI:23862462290270 PMID:15572153MGIPMID:15572153
Mmp14Mousecellular response to genistein  ISOMmp14 (Rattus norvegicus)9068941 RGDPMID:11125539 and REF_RGD_ID:2314953
Mmp14Mousechondrocyte proliferation acts_upstream_of_or_withinIGIMGI:12761072290270 PMID:18022611MGIPMID:18022611
Mmp14Mousecollagen catabolic process involved_inIBAPANTHER:PTN001303987 more ...2290270 GO_CentralGO_REF:0000033
Mmp14Mousecollagen catabolic process acts_upstream_of_or_withinIGIMGI:12761072290270 PMID:18022611MGIPMID:18022611
Mmp14Mousecraniofacial suture morphogenesis acts_upstream_of_or_withinIGIMGI:12761072290270 PMID:18022611MGIPMID:18022611
Mmp14Mouseembryonic cranial skeleton morphogenesis acts_upstream_of_or_withinIGIMGI:12761072290270 PMID:18022611MGIPMID:18022611
Mmp14Mouseendochondral ossification acts_upstream_of_or_withinIGIMGI:12761072290270 PMID:18022611MGIPMID:18022611
Mmp14Mouseendodermal cell differentiation involved_inIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mouseendothelial cell proliferation involved_inIEAUniProtKB:Q10739 and ensembl:ENSRNOP000000654342290270 EnsemblGO_REF:0000107
Mmp14Mouseendothelial cell proliferation  ISOMmp14 (Rattus norvegicus)9068941 RGDPMID:14766216 and REF_RGD_ID:1582561
Mmp14Mouseextracellular matrix organization involved_inIBAPANTHER:PTN001303987 more ...2290270 GO_CentralGO_REF:0000033
Mmp14Mousehead development acts_upstream_of_or_withinIMPMGI:37633592290270 PMID:26234751MGIPMID:26234751
Mmp14Mouselung development acts_upstream_of_or_withinIMPMGI:23862462290270 PMID:15572153MGIPMID:15572153
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Cellular Component
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Mmp14Mousecytoplasm located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousecytoplasmic vesicle located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousecytosol located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousecytosol located_inIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mouseextracellular matrix located_inIEAInterPro:IPR001818 and InterPro:IPR0211582290270 InterProGO_REF:0000002
Mmp14Mouseextracellular space located_inIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mouseextracellular space is_active_inIBAPANTHER:PTN002565758 more ...2290270 GO_CentralGO_REF:0000033
Mmp14Mouseextracellular space located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14MouseGolgi membrane located_inTAS 2290270 ReactomeReactome:R-MMU-9858820
Mmp14Mouseintermediate filament cytoskeleton located_inIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mouseintermediate filament cytoskeleton located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousemacropinosome located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousemacropinosome located_inIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mousemelanosome located_inIEAUniProtKB-SubCell:SL-01612290270 UniProtGO_REF:0000044
Mmp14Mousenucleus located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousenucleus located_inIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mouseplasma membrane located_inTAS 2290270 ReactomeReactome:R-MMU-9858820
Mmp14Mouseplasma membrane is_active_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mouseplasma membrane is_active_inIBAPANTHER:PTN002565544 and UniProtKB:P502812290270 GO_CentralGO_REF:0000033
Mmp14Mouseplasma membrane located_inISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
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Molecular Function
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Mmp14Mouseendopeptidase activity enablesISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mouseintegrin binding  ISOItgb1 (Rattus norvegicus)9068941 RGDPMID:19027888 and REF_RGD_ID:2307395
Mmp14Mouseintegrin binding enablesIEAUniProtKB:Q10739 and ensembl:ENSRNOP000000654342290270 EnsemblGO_REF:0000107
Mmp14Mouseintegrin binding enablesISOMmp14 (Rattus norvegicus)2290270 GO_CentralGO_REF:0000096
Mmp14Mousemetalloaminopeptidase activity enablesISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousemetalloaminopeptidase activity enablesIEAUniProtKB:P50281 and ensembl:ENSP000003082082290270 EnsemblGO_REF:0000107
Mmp14Mousemetalloendopeptidase activity enablesIMP 2290270 PMID:10737763 and PMID:24990232UniProtPMID:10737763 and PMID:24990232
Mmp14Mousemetalloendopeptidase activity enablesIDA 2290270 PMID:21572390UniProtPMID:21572390
Mmp14Mousemetalloendopeptidase activity enablesISOUniProtKB:P502812290270 GO_CentralGO_REF:0000119
Mmp14Mousemetalloendopeptidase activity enablesIBAPANTHER:PTN001303987 more ...2290270 GO_CentralGO_REF:0000033
Mmp14Mouseprotein binding enablesISOUniProtKB:Q9H7M99068941 PMID:20666777UniProtPMID:20666777
Mmp14Mouseprotein binding enablesISOUniProtKB:P099589068941 PMID:21152186IntActPMID:21152186
Mmp14Mouseprotein binding enablesISOUniProtKB:P27105 more ...9068941 PMID:32296183IntActPMID:32296183
Mmp14Mouseprotein binding enablesISOUniProtKB:P09958 and UniProtKB:Q9R0649068941 PMID:20608975IntActPMID:20608975
Mmp14Mouseprotein binding enablesISOUniProtKB:Q614839068941 PMID:21572390UniProtPMID:21572390
Mmp14Mouseprotein binding enablesISOUniProtKB:Q9BV579068941 PMID:14718544IntActPMID:14718544
Mmp14Mouseprotein binding enablesISOUniProtKB:P518849068941 PMID:25304424IntActPMID:25304424
Mmp14Mouseprotein binding enablesISOUniProtKB:P224559068941 PMID:20798051IntActPMID:20798051
Mmp14Mouseprotein binding enablesISOUniProtKB:P569459068941 PMID:18164686IntActPMID:18164686
Mmp14Mouseprotein binding enablesISOUniProtKB:Q8N6L09068941 PMID:25416956IntActPMID:25416956
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Imported Annotations - KEGG (archival)

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Mmp14Mousegonadotropin-releasing hormone signaling pathway  IEA 6907045 KEGGmmu:04912

Imported Annotations - PID (archival)

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Mmp14Mousehypoxia inducible factor pathway   ISOMMP14 (Homo sapiens)6484113 PIDPID:200036
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Mmp14Mouseabnormal axial skeleton morphology  IAGP 5509061 MGIPMID:10737763
Mmp14Mouseabnormal basement membrane morphology  IAGP 5509061 MGIPMID:20727881
Mmp14Mouseabnormal blood vessel morphology  IAGP 5509061 MGIPMID:15064723
Mmp14Mouseabnormal bone mineralization  IAGP 5509061 MGIPMID:10737763
Mmp14Mouseabnormal bone ossification  IAGP 5509061 MGIPMID:15064723
Mmp14Mouseabnormal bone ossification  IAGP 5509061 MGIPMID:23685250
Mmp14Mouseabnormal bone ossification  IAGP 5509061 MGIPMID:10737763
Mmp14Mouseabnormal bone ossification  IAGP 5509061 MGIPMID:10520996
Mmp14Mouseabnormal bone remodeling  IAGP 5509061 MGIPMID:14610065
Mmp14Mouseabnormal bronchiole morphology  IAGP 5509061 MGIPMID:15572153
Mmp14Mouseabnormal cartilage development  IAGP 5509061 MGIPMID:14610065
Mmp14Mouseabnormal cartilage development  IAGP 5509061 MGIPMID:10737763
Mmp14Mouseabnormal cartilage morphology  IAGP 5509061 MGIPMID:10520996
Mmp14Mouseabnormal cartilage morphology  IAGP 5509061 MGIPMID:23685250
Mmp14Mouseabnormal cartilage morphology  IAGP 5509061 MGIPMID:18022611
Mmp14Mouseabnormal chondrocyte morphology  IAGP 5509061 MGIPMID:14610065
Mmp14Mouseabnormal chondrocyte morphology  IAGP 5509061 MGIPMID:18022611
Mmp14Mouseabnormal chondrocyte morphology  IAGP 5509061 MGIPMID:10520996
Mmp14Mouseabnormal club cell morphology  IAGP 5509061 MGIPMID:15739229
Mmp14Mouseabnormal compact bone morphology  IAGP 5509061 MGIPMID:18022611
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Reference Title
Reference Citation
1. Up-regulation of matrix metalloproteinase-2 and membrane-type 1-matrix metalloproteinase were coupled with that of type I procollagen in granulation tissue response after the onset of aortic dissection. Akiyama M, etal., Virchows Arch. 2006 Jun;448(6):811-21. Epub 2006 Apr 12.
2. Differential regulation of matrix metalloproteinase activities in abdominal aortic aneurysms. Annabi B, etal., J Vasc Surg. 2002 Mar;35(3):539-46.
3. Upregulated expression and activation of membrane‑associated proteases in esophageal squamous cell carcinoma. Augoff K, etal., Oncol Rep. 2014 Jun;31(6):2820-6. doi: 10.3892/or.2014.3162. Epub 2014 Apr 29.
4. Vascular extracellular matrix remodeling in cerebral aneurysms. Bruno G, etal., J Neurosurg. 1998 Sep;89(3):431-40.
5. Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke. Buga AM, etal., PLoS One. 2012;7(12):e50985. doi: 10.1371/journal.pone.0050985. Epub 2012 Dec 12.
6. Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: the potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis. Choi EY, etal., Exp Mol Med. 2002 Dec 31;34(6):391-400.
7. Ischemia-induced cleavage of cadherins in NRK cells requires MT1-MMP (MMP-14). Covington MD, etal., Am J Physiol Renal Physiol. 2006 Jan;290(1):F43-51. Epub 2005 Aug 2.
8. Differential transcriptional activation of matrix metalloproteinase-2 and membrane type-1 matrix metalloproteinase by experimental deep venous thrombosis and thrombin. Dahi S, etal., J Vasc Surg. 2005 Sep;42(3):539-45.
9. MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells. Filippov S, etal., J Exp Med. 2005 Sep 5;202(5):663-71.
10. Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis. Hayashi K, etal., J Am Soc Nephrol. 1998 Dec;9(12):2262-71.
11. Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis. Hayashi K, etal., J Pathol. 2000 Jul;191(3):299-305.
12. Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia. Hosomi N, etal., Neuroscience. 2005;134(1):225-31.
13. Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome. Ikonomidis JS, etal., Circulation. 2006 Jul 4;114(1 Suppl):I365-70.
14. Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice. Kassiri Z, etal., Circ Res. 2005 Aug 19;97(4):380-90. Epub 2005 Jul 21.
15. Expression and tissue localization of membrane-types 1, 2, and 3 matrix metalloproteinases in human urothelial carcinomas. Kitagawa Y, etal., J Urol. 1998 Oct;160(4):1540-5.
16. MGDs mouse GO annotations MGD data from the GO Consortium
17. MGD IEA MGD IEA
18. Decreased vascular matrix metalloproteinase abundance in diabetic patients with symptomatic macroangiopathy. Mondy JS, etal., Ethn Dis. 2002 Fall;12(4):S3-18-22.
19. Elevated expression of extracellular matrix metalloproteinase inducer (CD147) and membrane-type matrix metalloproteinases in venous leg ulcers. Norgauer J, etal., Br J Dermatol. 2002 Dec;147(6):1180-6.
20. Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Okada A, etal., Proc Natl Acad Sci U S A 1995 Mar 28;92(7):2730-4.
1 to 20 of 32 rows
1 to 10 of 20 rows
PMID:8015608   PMID:8743942   PMID:9037199   PMID:9325265   PMID:9648071   PMID:10349636   PMID:10419448   PMID:10433819   PMID:10520996   PMID:10737763   PMID:10949577   PMID:11042159  
PMID:11076861   PMID:11165481   PMID:11217851   PMID:11221894   PMID:11359935   PMID:11675412   PMID:11747814   PMID:11828004   PMID:11865039   PMID:11973313   PMID:12049638   PMID:12477932  
PMID:12507218   PMID:12592384   PMID:12815621   PMID:12842442   PMID:12900459   PMID:12950084   PMID:12952212   PMID:12952213   PMID:14610065   PMID:14688206   PMID:14979875   PMID:15064723  
PMID:15094525   PMID:15304103   PMID:15456762   PMID:15516694   PMID:15522913   PMID:15545316   PMID:15557125   PMID:15563592   PMID:15572153   PMID:15601659   PMID:15695374   PMID:15734845  
PMID:15739229   PMID:15782199   PMID:15800063   PMID:15805464   PMID:15895410   PMID:15944163   PMID:15978592   PMID:16113801   PMID:16141072   PMID:16141073   PMID:16158179   PMID:16234249  
PMID:16236725   PMID:16251193   PMID:16551362   PMID:16678100   PMID:16778201   PMID:16926191   PMID:17018528   PMID:17136358   PMID:17204469   PMID:17229722   PMID:17393098   PMID:17405818  
PMID:17483344   PMID:17548469   PMID:17557804   PMID:17606763   PMID:17620416   PMID:17623673   PMID:17709990   PMID:18022611   PMID:18071307   PMID:18250269   PMID:18445063   PMID:18541723  
PMID:18627313   PMID:18639653   PMID:18663148   PMID:18762577   PMID:18799693   PMID:19010778   PMID:19051246   PMID:19066283   PMID:19085378   PMID:19197139   PMID:19264910   PMID:19371380  
PMID:19419317   PMID:19542530   PMID:19566825   PMID:19571574   PMID:19706774   PMID:19855192   PMID:19898483   PMID:19915148   PMID:20049897   PMID:20056917   PMID:20152179   PMID:20223936  
PMID:20356925   PMID:20418476   PMID:20620173   PMID:20643648   PMID:20660624   PMID:20663879   PMID:20727881   PMID:20858856   PMID:20978081   PMID:21267068   PMID:21372132   PMID:21436261  
1 to 10 of 20 rows



Mmp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,669,055 - 54,679,913 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,669,069 - 54,682,821 (+)EnsemblGRCm39 Ensembl
GRCm381454,431,598 - 54,442,456 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,431,612 - 54,445,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371455,050,441 - 55,060,095 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,385,824 - 53,395,458 (+)NCBIMGSCv36mm8
Celera1452,223,646 - 52,233,174 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.79NCBI
MMP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,836,585 - 22,847,758 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,836,560 - 22,849,041 (+)EnsemblGRCh38hg38GRCh38
GRCh371423,305,794 - 23,316,967 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,375,633 - 22,386,643 (+)NCBINCBI36Build 36hg18NCBI36
Build 341422,375,632 - 22,386,642NCBI
Celera143,168,679 - 3,179,688 (+)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,422,922 - 3,433,986 (+)NCBIHuRef
CHM1_11423,304,418 - 23,315,462 (+)NCBICHM1_1
T2T-CHM13v2.01417,034,651 - 17,045,822 (+)NCBIT2T-CHM13v2.0
Mmp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,857,824 - 31,867,049 (+)NCBIGRCr8
mRatBN7.21527,887,795 - 27,897,020 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,887,727 - 27,899,864 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,727,071 - 29,736,290 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,874,288 - 30,883,507 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,124,651 - 29,133,873 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,074,441 - 33,083,666 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,074,441 - 33,083,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,960,282 - 36,969,507 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,493,852 - 32,503,077 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,509,551 - 32,518,777 (+)NCBI
Celera1527,470,861 - 27,480,086 (+)NCBICelera
Cytogenetic Map15p13NCBI
Mmp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,440,541 - 37,448,437 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,438,924 - 37,448,704 (-)NCBIChiLan1.0ChiLan1.0
MMP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,266,301 - 24,277,533 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,482,405 - 23,494,022 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,654,125 - 3,665,158 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,753,305 - 21,764,061 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,753,305 - 21,764,058 (+)Ensemblpanpan1.1panPan2
MMP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,183,419 - 3,193,079 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,183,606 - 3,194,122 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,132,308 - 3,142,668 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,291,562 - 3,301,919 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,291,310 - 3,301,917 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.182,983,033 - 2,993,386 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,044,810 - 3,055,166 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,306,779 - 3,317,137 (+)NCBIUU_Cfam_GSD_1.0
Mmp14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,931,359 - 34,941,231 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,447,335 - 1,457,611 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,447,189 - 1,457,632 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,172,971 - 76,185,928 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,174,502 - 76,185,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,413,927 - 81,424,899 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,201,425 - 23,212,408 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,201,112 - 23,212,679 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,209,848 - 23,220,925 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,667,262 - 9,677,774 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,667,371 - 9,677,488 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Mmp14
346 total Variants

Predicted Target Of
Summary Value
Count of predictions:246
Count of miRNA genes:193
Interacting mature miRNAs:209
Transcripts:ENSMUST00000089688
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 23 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420887473121269804Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143504579768785736Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144296241676962593Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145376129687761529Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142106245071885801Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144296241676962593Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145228198486282125Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144306584777066045Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143032195787937436Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492624858179769Mouse

1 to 10 of 23 rows
AI325305  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,440,400 - 54,440,507UniSTSGRCm38
MGSCv371455,059,237 - 55,059,344UniSTSGRCm37
Celera1452,232,316 - 52,232,423UniSTS
Cytogenetic Map14C2UniSTS
cM Map1412.5UniSTS
Whitehead/MRC_RH14620.35UniSTS
Mmp14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371455,058,232 - 55,058,815UniSTSGRCm37
MGSCv371455,057,881 - 55,059,490UniSTSGRCm37
MGSCv371455,053,910 - 55,054,140UniSTSGRCm37
Celera1452,227,115 - 52,227,371UniSTS
Celera1452,231,306 - 52,231,889UniSTS
Celera1452,230,955 - 52,232,569UniSTS
Cytogenetic Map14C2UniSTS
cM Map1412.5UniSTS
cM Map1412.5UniSTS
cM Map1412.5UniSTS
MARC_9867-9868:996688667:1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,439,375 - 54,440,406UniSTSGRCm38
MGSCv371455,058,212 - 55,059,243UniSTSGRCm37
Celera1452,231,286 - 52,232,322UniSTS
Cytogenetic Map14C2UniSTS
cM Map1412.5UniSTS
Mmp14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,435,073 - 54,435,303UniSTSGRCm38
MGSCv371455,053,910 - 55,054,140UniSTSGRCm37
Celera1452,227,115 - 52,227,371UniSTS
Cytogenetic Map14C2UniSTS
cM Map1412.5UniSTS
Mmp14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,439,044 - 54,440,653UniSTSGRCm38
MGSCv371455,057,881 - 55,059,490UniSTSGRCm37
Celera1452,230,955 - 52,232,569UniSTS
Cytogenetic Map14C2UniSTS
cM Map1412.5UniSTS
MMP14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381454,439,395 - 54,439,978UniSTSGRCm38
MGSCv371455,058,232 - 55,058,815UniSTSGRCm37
Celera1452,231,306 - 52,231,889UniSTS
Cytogenetic Map14C2UniSTS
Mmp14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14C2UniSTS






1 to 30 of 49 rows
RefSeq Transcripts NM_008608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC164433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC206013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK149988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK182471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 49 rows

Ensembl Acc Id: ENSMUST00000089688   ⟹   ENSMUSP00000087119
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,669,069 - 54,678,722 (+)Ensembl
GRCm38.p6 Ensembl1454,431,612 - 54,441,265 (+)Ensembl
Ensembl Acc Id: ENSMUST00000196155   ⟹   ENSMUSP00000143012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,669,893 - 54,673,329 (+)Ensembl
GRCm38.p6 Ensembl1454,432,436 - 54,435,872 (+)Ensembl
Ensembl Acc Id: ENSMUST00000197874   ⟹   ENSMUSP00000142665
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,669,080 - 54,673,645 (+)Ensembl
GRCm38.p6 Ensembl1454,431,623 - 54,436,188 (+)Ensembl
Ensembl Acc Id: ENSMUST00000197947
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,669,121 - 54,673,617 (+)Ensembl
GRCm38.p6 Ensembl1454,431,664 - 54,436,160 (+)Ensembl
Ensembl Acc Id: ENSMUST00000198679
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,669,175 - 54,670,722 (+)Ensembl
GRCm38.p6 Ensembl1454,431,718 - 54,433,265 (+)Ensembl
Ensembl Acc Id: ENSMUST00000225641   ⟹   ENSMUSP00000153679
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,669,090 - 54,682,821 (+)Ensembl
GRCm38.p6 Ensembl1454,431,633 - 54,445,364 (+)Ensembl
Ensembl Acc Id: ENSMUST00000226710
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1454,676,049 - 54,677,936 (+)Ensembl
GRCm38.p6 Ensembl1454,438,592 - 54,440,479 (+)Ensembl
RefSeq Acc Id: NM_008608   ⟹   NP_032634
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391454,669,055 - 54,679,913 (+)NCBI
GRCm381454,431,598 - 54,442,456 (+)NCBI
MGSCv371455,050,441 - 55,060,095 (+)RGD
Celera1452,223,646 - 52,233,174 (+)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_032634   ⟸   NM_008608
- Peptide Label: preproprotein
- UniProtKB: O35369 (UniProtKB/Swiss-Prot),   O08645 (UniProtKB/Swiss-Prot),   Q8BTX2 (UniProtKB/Swiss-Prot),   P53690 (UniProtKB/Swiss-Prot),   Q3TQH0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000142665   ⟸   ENSMUST00000197874
Ensembl Acc Id: ENSMUSP00000153679   ⟸   ENSMUST00000225641
Ensembl Acc Id: ENSMUSP00000087119   ⟸   ENSMUST00000089688
Ensembl Acc Id: ENSMUSP00000143012   ⟸   ENSMUST00000196155
Peptidase M10A matrix metallopeptidase C-terminal   Peptidase metallopeptidase

Name Modeler Protein Id AA Range Protein Structure
AF-P53690-F1-model_v2 AlphaFold P53690 1-582 view protein structure

RGD ID:8682338
Promoter ID:EPDNEW_M19199
Type:initiation region
Name:Mmp14_1
Description:Mus musculus matrix metallopeptidase 14 (membrane-inserted) ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381454,431,648 - 54,431,708EPDNEW
RGD ID:6825184
Promoter ID:MM_KWN:16869
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000089688
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361455,049,451 - 55,050,652 (+)MPROMDB


1 to 40 of 56 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSMUSG00000000957 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000089688 ENTREZGENE
  ENSMUST00000089688.6 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.101.10 UniProtKB/Swiss-Prot
  2.110.10.10 UniProtKB/Swiss-Prot
  3.40.390.10 UniProtKB/Swiss-Prot
InterPro Hemopexin-like_dom UniProtKB/Swiss-Prot
  Hemopexin-like_dom_sf UniProtKB/Swiss-Prot
  Hemopexin-like_repeat UniProtKB/Swiss-Prot
  Hemopexin_CS UniProtKB/Swiss-Prot
  M10A_MMP UniProtKB/Swiss-Prot
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot
  Pept_M10A UniProtKB/Swiss-Prot
  Pept_M10A_metallopeptidase_C UniProtKB/Swiss-Prot
  Pept_M10A_Zn_BS UniProtKB/Swiss-Prot
  Peptidase_Metallo UniProtKB/Swiss-Prot
  Peptidoglycan-bd-like UniProtKB/Swiss-Prot
  PGBD-like_sf UniProtKB/Swiss-Prot
  PGBDSf UniProtKB/Swiss-Prot
KEGG Report mmu:17387 UniProtKB/Swiss-Prot
MGD MGI:101900 ENTREZGENE
NCBI Gene 17387 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/Swiss-Prot
  MATRIX METALLOPROTEINASE-14 UniProtKB/Swiss-Prot
Pfam DUF3377 UniProtKB/Swiss-Prot
  Hemopexin UniProtKB/Swiss-Prot
  Peptidase_M10 UniProtKB/Swiss-Prot
  PG_binding_1 UniProtKB/Swiss-Prot
PhenoGen Mmp14 PhenoGen
PIRSF Peptidase_M10A_matrix UniProtKB/Swiss-Prot
PRINTS MATRIXIN UniProtKB/Swiss-Prot
PROSITE CYSTEINE_SWITCH UniProtKB/Swiss-Prot
  HEMOPEXIN UniProtKB/Swiss-Prot
  HEMOPEXIN_2 UniProtKB/Swiss-Prot
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART SM00120 UniProtKB/Swiss-Prot
  ZnMc UniProtKB/Swiss-Prot
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot
  SSF47090 UniProtKB/Swiss-Prot
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