Mmp14 (matrix metallopeptidase 14) - Rat Genome Database

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Gene: Mmp14 (matrix metallopeptidase 14) Ictidomys tridecemlineatus
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Symbol: Mmp14
Name: matrix metallopeptidase 14
RGD ID: 12594073
Description: ENCODES a protein that exhibits endopeptidase activity (ortholog); integrin binding (ortholog); metalloaminopeptidase activity (ortholog); INVOLVED IN angiogenesis (ortholog); astrocyte cell migration (ortholog); bone development (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); adenocarcinoma (ortholog); anti-basement membrane glomerulonephritis (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: matrix metalloproteinase-14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,931,359 - 34,941,231 (+)NCBI
SpeTri2.0NW_0049367221,447,189 - 1,457,632 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Mmp14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,931,359 - 34,941,231 (+)NCBI
SpeTri2.0NW_0049367221,447,189 - 1,457,632 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1422,836,560 - 22,849,027 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1422,836,560 - 22,849,041 (+)EnsemblGRCh38hg38GRCh38
GRCh381422,836,585 - 22,847,758 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371423,305,794 - 23,316,967 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,375,633 - 22,386,643 (+)NCBINCBI36hg18NCBI36
Build 341422,375,632 - 22,386,642NCBI
Celera143,168,679 - 3,179,688 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef143,422,922 - 3,433,986 (+)NCBIHuRef
CHM1_11423,304,418 - 23,315,462 (+)NCBICHM1_1
Mmp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,669,055 - 54,679,913 (+)NCBIGRCm39mm39
GRCm39 Ensembl1454,669,069 - 54,682,821 (+)Ensembl
GRCm381454,431,598 - 54,442,456 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,431,612 - 54,445,364 (+)EnsemblGRCm38mm10GRCm38
MGSCv371455,050,441 - 55,060,095 (+)NCBIGRCm37mm9NCBIm37
MGSCv361453,385,824 - 53,395,458 (+)NCBImm8
Celera1452,223,646 - 52,233,174 (+)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.79NCBI
Mmp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21527,887,795 - 27,897,020 (+)NCBI
Rnor_6.0 Ensembl1533,074,441 - 33,083,655 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01533,074,441 - 33,083,666 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01536,960,282 - 36,969,507 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,493,852 - 32,503,077 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11532,509,551 - 32,518,777 (+)NCBI
Celera1527,470,861 - 27,480,086 (+)NCBICelera
Cytogenetic Map15p13NCBI
Mmp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,440,541 - 37,448,437 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,438,924 - 37,448,704 (-)NCBIChiLan1.0ChiLan1.0
MMP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11421,753,305 - 21,764,061 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,753,305 - 21,764,058 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0143,654,125 - 3,665,158 (+)NCBIMhudiblu_PPA_v0panPan3
MMP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,183,419 - 3,193,079 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,183,606 - 3,194,122 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,132,308 - 3,142,668 (+)NCBI
ROS_Cfam_1.083,291,562 - 3,301,919 (+)NCBI
UMICH_Zoey_3.182,983,033 - 2,993,386 (+)NCBI
UNSW_CanFamBas_1.083,044,810 - 3,055,166 (+)NCBI
UU_Cfam_GSD_1.083,306,779 - 3,317,137 (+)NCBI
MMP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,174,500 - 76,185,923 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,174,502 - 76,185,931 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,413,927 - 81,424,899 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP14
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,201,425 - 23,212,408 (+)NCBI
ChlSab1.1 Ensembl2923,201,112 - 23,212,679 (+)Ensembl
Mmp14
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248209,667,371 - 9,677,488 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005338789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005338789   ⟹   XP_005338846
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864034,931,359 - 34,941,231 (+)NCBI
SpeTri2.0NW_0049367221,447,189 - 1,457,632 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005338846 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005338846   ⟸   XM_005338789
- UniProtKB: I3N925 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
ZnMc


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000027121 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000020871 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000027449 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A UniProtKB/TrEMBL
  Pept_M10A_metallopeptidase_C UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/TrEMBL
NCBI Gene Mmp14 ENTREZGENE
Pfam DUF3377 UniProtKB/TrEMBL
  Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/TrEMBL
  HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP SSF47090 UniProtKB/TrEMBL
  SSF50923 UniProtKB/TrEMBL
UniProt I3N925 ENTREZGENE, UniProtKB/TrEMBL