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Gene: MMP15 (matrix metallopeptidase 15) Homo sapiens
Symbol: MMP15
Name: matrix metallopeptidase 15
Description: Predicted to have metalloendopeptidase activity. Involved in endodermal cell differentiation. Predicted to localize to plasma membrane. Biomarker of prostate cancer and transitional cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: matrix metallopeptidase 15 (membrane-inserted); matrix metalloproteinase 15 (membrane-inserted); matrix metalloproteinase-15; membrane-type matrix metalloproteinase 2; membrane-type-2 matrix metalloproteinase; MMP-15; MT-MMP 2; MT2-MMP; MT2MMP; MTMMP2; SMCP-2
Mus musculus (house mouse) : Mmp15 (matrix metallopeptidase 15)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mmp15 (matrix metallopeptidase 15)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp15 (matrix metallopeptidase 15)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP15 (matrix metallopeptidase 15)
Canis lupus familiaris (dog) : MMP15 (matrix metallopeptidase 15)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp15 (matrix metallopeptidase 15)
Sus scrofa (pig) : MMP15 (matrix metallopeptidase 15)
Chlorocebus sabaeus (African green monkey) : MMP15 (matrix metallopeptidase 15)
Heterocephalus glaber (naked mole-rat) : Mmp15 (matrix metallopeptidase 15)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1658,025,754 - 58,046,901 (+)EnsemblGRCh38hg38GRCh38
GRCh381658,025,754 - 58,046,901 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371658,059,282 - 58,080,805 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361656,616,783 - 56,638,306 (+)NCBINCBI36hg18NCBI36
Build 341656,616,782 - 56,638,303NCBI
Celera1642,556,594 - 42,578,117 (+)NCBI
Cytogenetic Map16q21NCBI
HuRef1643,926,416 - 43,947,940 (+)NCBIHuRef
CHM1_11659,466,544 - 59,487,878 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MMP15
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318995
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.