Tyro3 (TYRO3 protein tyrosine kinase 3) - Rat Genome Database

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Gene: Tyro3 (TYRO3 protein tyrosine kinase 3) Mus musculus
Analyze
Symbol: Tyro3
Name: TYRO3 protein tyrosine kinase 3
RGD ID: 11467
MGI Page MGI
Description: Predicted to enable phosphatidylinositol 3-kinase binding activity; transmembrane receptor protein tyrosine kinase activity; and virus receptor activity. Involved in several processes, including negative regulation of defense response; platelet aggregation; and protein kinase B signaling. Acts upstream of or within several processes, including animal organ development; platelet activation; and substrate adhesion-dependent cell spreading. Predicted to be located in cell surface; endoplasmic reticulum membrane; and nuclear envelope. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; limb; and sensory organ. Orthologous to human TYRO3 (TYRO3 protein tyrosine kinase); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323366; Br; Brt; Dtk; Etk-2; etk2/tyro3; R; receptor tyrosine kinase; Rse; Sk; Sky; Ti; Tif; tk19-1; TK19-2; tyrosine kinase growth factor receptor; tyrosine kinase growth factor receptor isoform III; tyrosine-protein kinase DTK; tyrosine-protein kinase receptor TYRO3; tyrosine-protein kinase RSE; tyrosine-protein kinase TIF
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Tyro3-rs1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,628,221 - 119,648,585 (+)NCBIGRCm39mm39
GRCm39 Ensembl2119,628,214 - 119,648,585 (+)Ensembl
GRCm382119,797,740 - 119,818,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,797,733 - 119,818,104 (+)EnsemblGRCm38mm10GRCm38
MGSCv372119,625,250 - 119,643,840 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,490,955 - 119,509,545 (+)NCBImm8
Celera2120,956,991 - 120,973,578 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2,4-trimethylbenzene  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
6-propyl-2-thiouracil  (ISO)
ADP  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chlordecone  (EXP)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (EXP)
fenvalerate  (ISO)
gamma-hexachlorocyclohexane  (ISO)
genistein  (ISO)
hydrogen peroxide  (ISO)
methotrexate  (EXP)
methoxychlor  (ISO)
N-nitrosodiethylamine  (ISO)
naphthalenes  (ISO)
nickel atom  (ISO)
nickel sulfate  (EXP)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
retinyl acetate  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
temozolomide  (ISO)
Tesaglitazar  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
undecane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
warfarin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal B cell activation  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal body weight  (IAGP)
abnormal brain thrombosis  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal forebrain development  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal head movements  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal hypothalamus morphology  (IAGP)
abnormal macrophage physiology  (IAGP)
abnormal neuronal migration  (IAGP)
abnormal platelet activation  (IAGP)
abnormal platelet morphology  (IAGP)
abnormal professional antigen presenting cell physiology  (IAGP)
abnormal prostate gland epithelium morphology  (IAGP)
abnormal seizure response to inducing agent  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal spermatogenesis  (IAGP)
abnormal survival  (IAGP)
abnormal susceptibility to autoimmune disorder  (IAGP)
abnormal T cell activation  (IAGP)
abnormal thrombosis  (IAGP)
abnormal uterus morphology  (IAGP)
azoospermia  (IAGP)
blindness  (IAGP)
cachexia  (IAGP)
decreased Sertoli cell phagocytosis  (IAGP)
delayed estrous cycle  (IAGP)
delayed sexual maturation  (IAGP)
enlarged lymph nodes  (IAGP)
enlarged spleen  (IAGP)
enlarged uterus  (IAGP)
increased anti-double stranded DNA antibody level  (IAGP)
increased apoptosis  (IAGP)
increased autoantibody level  (IAGP)
increased B cell proliferation  (IAGP)
increased brain apoptosis  (IAGP)
increased circulating tumor necrosis factor level  (IAGP)
increased granulosa cell apoptosis  (IAGP)
increased lymphocyte cell number  (IAGP)
increased neuron apoptosis  (IAGP)
increased splenocyte apoptosis  (IAGP)
increased T cell proliferation  (IAGP)
internal hemorrhage  (IAGP)
joint inflammation  (IAGP)
liver degeneration  (IAGP)
male infertility  (IAGP)
oligozoospermia  (IAGP)
premature death  (IAGP)
prolonged estrous cycle  (IAGP)
prolonged proestrus  (IAGP)
reduced female fertility  (IAGP)
retinal cone cell degeneration  (IAGP)
retinal rod cell degeneration  (IAGP)
short diestrus  (IAGP)
skin lesions  (IAGP)
small endometrial glands  (IAGP)
small testis  (IAGP)
tremors  (IAGP)
vagina atresia  (IAGP)
References

Additional References at PubMed
PMID:479391   PMID:2025425   PMID:2466296   PMID:3291115   PMID:6595305   PMID:7511603   PMID:7542761   PMID:7723626   PMID:7784069   PMID:7857657   PMID:7867073   PMID:7893599  
PMID:7896835   PMID:7984037   PMID:8058320   PMID:8108111   PMID:8108112   PMID:8262388   PMID:8346215   PMID:8661736   PMID:8808274   PMID:8889809   PMID:8954722   PMID:9070938  
PMID:9223619   PMID:9331176   PMID:9362459   PMID:9593828   PMID:9593916   PMID:9670959   PMID:9844012   PMID:9846490   PMID:10227296   PMID:10349636   PMID:10395190   PMID:10436066  
PMID:10922068   PMID:11042159   PMID:11076861   PMID:11113536   PMID:11114734   PMID:11217851   PMID:11290399   PMID:11522958   PMID:11529277   PMID:12477932   PMID:12802202   PMID:12904583  
PMID:14610273   PMID:14695357   PMID:15650770   PMID:15782199   PMID:16006007   PMID:16141072   PMID:16141073   PMID:16365397   PMID:16602821   PMID:16723520   PMID:16751775   PMID:16901715  
PMID:17442946   PMID:17488688   PMID:17560618   PMID:18083102   PMID:18159085   PMID:18188450   PMID:18393392   PMID:18787040   PMID:18799693   PMID:18812457   PMID:19602523   PMID:19625016  
PMID:19729839   PMID:19805117   PMID:20348395   PMID:20363878   PMID:20483720   PMID:20546121   PMID:20692344   PMID:20967882   PMID:21084607   PMID:21192804   PMID:21267068   PMID:21438125  
PMID:21467176   PMID:21539887   PMID:21805534   PMID:21873635   PMID:22025706   PMID:22043818   PMID:22701746   PMID:23071254   PMID:23259948   PMID:23632195   PMID:23799121   PMID:23840307  
PMID:24244024   PMID:24509082   PMID:24952961   PMID:24978606   PMID:25194421   PMID:25265470   PMID:25514676   PMID:25826454   PMID:26523970   PMID:26656104   PMID:27034374   PMID:27571008  
PMID:28093506   PMID:28145605   PMID:28423319   PMID:28668391   PMID:29382817   PMID:30208252   PMID:30212841   PMID:30335822   PMID:30429374   PMID:30541554   PMID:30735494   PMID:31230815  
PMID:31346082  


Genomics

Comparative Map Data
Tyro3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,628,221 - 119,648,585 (+)NCBIGRCm39mm39
GRCm39 Ensembl2119,628,214 - 119,648,585 (+)Ensembl
GRCm382119,797,740 - 119,818,104 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2119,797,733 - 119,818,104 (+)EnsemblGRCm38mm10GRCm38
MGSCv372119,625,250 - 119,643,840 (+)NCBIGRCm37mm9NCBIm37
MGSCv362119,490,955 - 119,509,545 (+)NCBImm8
Celera2120,956,991 - 120,973,578 (+)NCBICelera
Cytogenetic Map2E5NCBI
cM Map259.97NCBI
TYRO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1541,557,675 - 41,583,589 (+)EnsemblGRCh38hg38GRCh38
GRCh381541,559,212 - 41,583,589 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371541,851,410 - 41,875,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361539,638,524 - 39,658,818 (+)NCBINCBI36hg18NCBI36
Build 341539,638,523 - 39,658,818NCBI
Celera1518,619,191 - 18,639,503 (+)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1518,699,536 - 18,719,735 (+)NCBIHuRef
CHM1_11541,969,757 - 41,990,068 (+)NCBICHM1_1
Tyro3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23106,777,686 - 106,797,154 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl3106,777,635 - 106,797,142 (+)Ensembl
Rnor_6.03111,597,102 - 111,616,142 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,597,102 - 111,616,142 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,145,366 - 118,165,796 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,309,671 - 106,328,607 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13106,206,098 - 106,225,035 (+)NCBI
Celera3105,690,533 - 105,707,759 (+)NCBICelera
Cytogenetic Map3q35NCBI
Tyro3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554168,359,207 - 8,377,692 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554168,361,722 - 8,377,629 (+)NCBIChiLan1.0ChiLan1.0
TYRO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11538,739,509 - 38,760,288 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1538,739,509 - 38,760,288 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01520,499,789 - 20,520,152 (+)NCBIMhudiblu_PPA_v0panPan3
TYRO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1308,571,230 - 8,602,655 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl308,571,475 - 8,598,721 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha308,630,043 - 8,657,391 (+)NCBI
ROS_Cfam_1.0308,705,504 - 8,732,865 (+)NCBI
UMICH_Zoey_3.1308,626,748 - 8,654,350 (+)NCBI
UNSW_CanFamBas_1.0308,745,727 - 8,761,952 (+)NCBI
UU_Cfam_GSD_1.0308,865,937 - 8,893,363 (+)NCBI
Tyro3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,044,633 - 87,062,702 (+)NCBI
SpeTri2.0NW_0049364714,893,185 - 4,910,779 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TYRO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1129,811,539 - 129,828,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11129,811,540 - 129,829,395 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,883,363 - 144,900,853 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TYRO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12641,429,667 - 41,449,130 (-)NCBI
ChlSab1.1 Ensembl2641,429,556 - 41,449,175 (-)Ensembl
Vero_WHO_p1.0NW_02366604899,532,509 - 99,554,583 (+)NCBI
Tyro3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248048,711,487 - 8,729,025 (+)NCBI

Position Markers
AI323366  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,817,816 - 119,817,960UniSTSGRCm38
MGSCv372119,643,552 - 119,643,696UniSTSGRCm37
Celera2120,973,290 - 120,973,434UniSTS
Cytogenetic Map2FUniSTS
cM Map267.1UniSTS
Whitehead/MRC_RH21517.42UniSTS
Tyro3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,798,238 - 119,798,563UniSTSGRCm38
MGSCv372119,623,974 - 119,624,299UniSTSGRCm37
Celera2120,953,740 - 120,954,065UniSTS
Cytogenetic Map2FUniSTS
cM Map267.1UniSTS
D15S1348  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,817,143 - 119,817,379UniSTSGRCm38
MGSCv372119,642,879 - 119,643,115UniSTSGRCm37
Celera2120,972,617 - 120,972,853UniSTS
Cytogenetic Map2FUniSTS
cM Map267.1UniSTS
Tyro3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,817,333 - 119,817,488UniSTSGRCm38
MGSCv372119,643,069 - 119,643,224UniSTSGRCm37
Celera2120,972,807 - 120,972,962UniSTS
Cytogenetic Map2FUniSTS
cM Map267.1UniSTS
Tyro3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,817,256 - 119,817,474UniSTSGRCm38
MGSCv372119,642,992 - 119,643,210UniSTSGRCm37
Celera2120,972,730 - 120,972,948UniSTS
Cytogenetic Map2FUniSTS
cM Map267.1UniSTS
Tyro3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382119,817,243 - 119,817,449UniSTSGRCm38
MGSCv372119,642,979 - 119,643,185UniSTSGRCm37
Celera2120,972,717 - 120,972,923UniSTS
Cytogenetic Map2FUniSTS
cM Map267.1UniSTS
Tyro3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2FUniSTS
Tyro3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2FUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111331784145331901Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106391660140391809Mouse
1301834Bits1_mbitterness sensitivity 1 (mouse)Not determined287610298121610433Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112194642128331901Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2118112449174483070Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224334620148858457Mouse
1558825Aabpr_maberrant activation of B cell proliferation (mouse)Not determined2116202748122377053Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111781466145781606Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2101112449135112609Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2101112449135112609Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111331784145331901Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112194642128331901Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111331784145331901Mouse
1301909Smdq2_msegregation of mitochondrial DNA QTL 2 (mouse)Not determined292948120126948262Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111331784145331901Mouse
1300852Lmr14_mleishmaniasis resistance 14 (mouse)Not determined286265371120265478Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114457594132872237Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116464410150464554Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2101112449135112609Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245457623145470727Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111709108145709243Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110647738144647887Mouse
1301098Cd8mts3_mCD8 memory T cell subset 3 (mouse)Not determined291259629125259759Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284182854148680255Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116235703150235821Mouse
4142223Femwf4_mfemur work to failure 4 (mouse)Not determined88313078122313225Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285893925181254801Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265439402162677006Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107413756141413756Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284182854148825550Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2111085773154512747Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100993579134993788Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229417935148533014Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118758772160769245Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115370937149371074Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112370826146371085Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103265371129371085Mouse
11038697Ltpr2d_mLeishmania tropica response 2d (mouse)286265371120265478Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102800000160100000Mouse
11038698Ltpr2c_mLeishmania tropica response 2c (mouse)286265371120265478Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297292889131293051Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115370937149371074Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118758772160769245Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297292889131293051Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274693773129371085Mouse
12904007Cfq7_mconditioned fear QTL 7 (mouse)2118526291125206952Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294400000154400000Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118758772160769245Mouse
11532731Sluc31a_msusceptibility to lung cancer 31a (mouse)288184658122184825Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118758772160769245Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297379883131379883Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)262000000137000000Mouse
11049565Lmr28g_mleishmaniasis resistance 28g (mouse)286265371120265478Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297379883131379883Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112370826146371085Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103265371167370436Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112370826146371085Mouse
13506762Tbvq2_mtrabecular bone volume QTL 2 (mouse)2115600000124900000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1675
Count of miRNA genes:634
Interacting mature miRNAs:780
Transcripts:ENSMUST00000028763, ENSMUST00000110783, ENSMUST00000130456, ENSMUST00000135726, ENSMUST00000137135, ENSMUST00000147636, ENSMUST00000147761, ENSMUST00000148343
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001290800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_019392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB000826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB000827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB000828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH006738 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL844896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC066058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D17393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L10914 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U05683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U27128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X78103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000028763   ⟹   ENSMUSP00000028763
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,629,995 - 119,648,585 (+)Ensembl
GRCm38.p6 Ensembl2119,799,514 - 119,818,104 (+)Ensembl
RefSeq Acc Id: ENSMUST00000110783   ⟹   ENSMUSP00000106410
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,628,214 - 119,648,585 (+)Ensembl
GRCm38.p6 Ensembl2119,797,733 - 119,818,104 (+)Ensembl
RefSeq Acc Id: ENSMUST00000130456
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,633,568 - 119,638,471 (+)Ensembl
GRCm38.p6 Ensembl2119,803,087 - 119,807,990 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135726
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,631,597 - 119,633,774 (+)Ensembl
GRCm38.p6 Ensembl2119,801,116 - 119,803,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000137135
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,641,327 - 119,642,872 (+)Ensembl
GRCm38.p6 Ensembl2119,810,846 - 119,812,391 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147636
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,629,720 - 119,636,131 (+)Ensembl
GRCm38.p6 Ensembl2119,799,239 - 119,805,650 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147761
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,639,689 - 119,648,572 (+)Ensembl
GRCm38.p6 Ensembl2119,809,208 - 119,818,091 (+)Ensembl
RefSeq Acc Id: ENSMUST00000148343
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2119,629,808 - 119,633,816 (+)Ensembl
GRCm38.p6 Ensembl2119,799,327 - 119,803,335 (+)Ensembl
RefSeq Acc Id: NM_001290800   ⟹   NP_001277729
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392119,628,221 - 119,648,585 (+)NCBI
GRCm382119,797,740 - 119,818,104 (+)NCBI
Celera2120,953,242 - 120,973,578 (+)NCBI
Sequence:
RefSeq Acc Id: NM_019392   ⟹   NP_062265
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392119,629,995 - 119,648,585 (+)NCBI
GRCm382119,799,514 - 119,818,104 (+)NCBI
MGSCv372119,625,250 - 119,643,840 (+)RGD
Celera2120,953,242 - 120,973,578 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006499160   ⟹   XP_006499223
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392119,631,602 - 119,648,585 (+)NCBI
GRCm382119,801,121 - 119,818,104 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017317147   ⟹   XP_017172636
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392119,629,813 - 119,648,585 (+)NCBI
GRCm382119,799,332 - 119,818,104 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_062265   ⟸   NM_019392
- Peptide Label: isoform A precursor
- UniProtKB: P55144 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006499223   ⟸   XM_006499160
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001277729   ⟸   NM_001290800
- Peptide Label: isoform B
- UniProtKB: P55144 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017172636   ⟸   XM_017317147
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000106410   ⟸   ENSMUST00000110783
RefSeq Acc Id: ENSMUSP00000028763   ⟸   ENSMUST00000028763
Promoters
RGD ID:6833012
Promoter ID:MM_KWN:31266
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000039947
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362119,626,566 - 119,627,066 (+)MPROMDB
RGD ID:6833014
Promoter ID:MM_KWN:31267
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000039948
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362119,628,466 - 119,628,966 (+)MPROMDB
RGD ID:6833013
Promoter ID:MM_KWN:31268
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000039944
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362119,634,866 - 119,635,366 (+)MPROMDB
RGD ID:6833015
Promoter ID:MM_KWN:31269
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000039949
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362119,636,316 - 119,636,816 (+)MPROMDB
RGD ID:6878380
Promoter ID:EPDNEW_M2641
Type:initiation region
Name:Tyro3_1
Description:Mus musculus TYRO3 protein tyrosine kinase 3 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2642  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382119,799,550 - 119,799,610EPDNEW
RGD ID:6878382
Promoter ID:EPDNEW_M2642
Type:initiation region
Name:Tyro3_2
Description:Mus musculus TYRO3 protein tyrosine kinase 3 , transcript variant1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M2641  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382119,799,770 - 119,799,830EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104294 AgrOrtholog
Ensembl Genes ENSMUSG00000027298 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000028763 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000106410 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028763 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000110783 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22174 UniProtKB/Swiss-Prot
MGD MGI:104294 ENTREZGENE
NCBI Gene 22174 ENTREZGENE
Pfam fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_Tyr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tyro3 PhenoGen
PRINTS TYRKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TyrKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P55144 ENTREZGENE
  Q62121_MOUSE UniProtKB/TrEMBL
  TYRO3_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O09070 UniProtKB/Swiss-Prot
  O09080 UniProtKB/Swiss-Prot
  P70285 UniProtKB/Swiss-Prot
  Q60752 UniProtKB/Swiss-Prot
  Q62482 UniProtKB/Swiss-Prot
  Q62483 UniProtKB/Swiss-Prot
  Q62484 UniProtKB/Swiss-Prot
  Q6NZM6 UniProtKB/Swiss-Prot
  Q78E85 UniProtKB/Swiss-Prot
  Q78E87 UniProtKB/Swiss-Prot