Kcnv1 (potassium channel, subfamily V, member 1) - Rat Genome Database

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Gene: Kcnv1 (potassium channel, subfamily V, member 1) Mus musculus
Analyze
Symbol: Kcnv1
Name: potassium channel, subfamily V, member 1
RGD ID: 731336
MGI Page MGI
Description: Predicted to enable voltage-gated potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to act upstream of or within ion transport and regulation of ion transmembrane transport. Predicted to be located in intercellular bridge and plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be integral component of membrane. Orthologous to human KCNV1 (potassium voltage-gated channel modifier subfamily V member 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2700023A03Rik; neuronal potassium channel alpha subunit; potassium channel Kv8.1 homolog; potassium voltage-gated channel subfamily V member 1; vibe; voltage-gated potassium channel subunit Kv8.1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391544,959,482 - 44,979,375 (-)NCBIGRCm39mm39
GRCm39 Ensembl1544,969,680 - 44,978,316 (-)Ensembl
GRCm381545,096,086 - 45,115,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1545,106,284 - 45,114,920 (-)EnsemblGRCm38mm10GRCm38
MGSCv371544,937,830 - 44,946,480 (-)NCBIGRCm37mm9NCBIm37
MGSCv361544,936,358 - 44,944,901 (-)NCBImm8
Celera1545,557,088 - 45,565,718 (-)NCBICelera
Cytogenetic Map15B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16985003   PMID:21267068   PMID:21677750   PMID:21873635   PMID:32325033  


Genomics

Comparative Map Data
Kcnv1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391544,959,482 - 44,979,375 (-)NCBIGRCm39mm39
GRCm39 Ensembl1544,969,680 - 44,978,316 (-)Ensembl
GRCm381545,096,086 - 45,115,912 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1545,106,284 - 45,114,920 (-)EnsemblGRCm38mm10GRCm38
MGSCv371544,937,830 - 44,946,480 (-)NCBIGRCm37mm9NCBIm37
MGSCv361544,936,358 - 44,944,901 (-)NCBImm8
Celera1545,557,088 - 45,565,718 (-)NCBICelera
Cytogenetic Map15B3.3NCBI
KCNV1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388109,963,636 - 109,975,771 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl8109,963,636 - 109,975,771 (-)EnsemblGRCh38hg38GRCh38
GRCh378110,975,865 - 110,988,000 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368111,048,409 - 111,056,135 (-)NCBINCBI36hg18NCBI36
Build 348111,048,410 - 111,056,135NCBI
Celera8107,166,854 - 107,174,580 (-)NCBI
Cytogenetic Map8q23.2NCBI
HuRef8106,301,223 - 106,308,930 (-)NCBIHuRef
CHM1_18111,019,498 - 111,027,224 (-)NCBICHM1_1
T2T-CHM13v2.08111,092,275 - 111,104,410 (-)NCBI
Kcnv1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2776,260,695 - 76,269,170 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl776,260,695 - 76,269,170 (-)Ensembl
Rnor_6.0784,016,864 - 84,023,205 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl784,015,207 - 84,023,316 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0784,031,382 - 84,037,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4781,012,246 - 81,018,587 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1781,032,975 - 81,039,317 (-)NCBI
Celera773,232,467 - 73,238,820 (-)NCBICelera
Cytogenetic Map7q31NCBI
Kcnv1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541717,292,459 - 17,299,241 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541717,292,459 - 17,298,773 (-)NCBIChiLan1.0ChiLan1.0
KCNV1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.18108,758,296 - 108,770,506 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8108,761,656 - 108,770,506 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v08106,616,952 - 106,627,423 (-)NCBIMhudiblu_PPA_v0panPan3
KCNV1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11310,440,159 - 10,449,369 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1310,443,595 - 10,450,005 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1310,430,455 - 10,439,600 (-)NCBI
ROS_Cfam_1.01310,721,039 - 10,730,178 (-)NCBI
ROS_Cfam_1.0 Ensembl1310,721,400 - 10,730,886 (-)Ensembl
UMICH_Zoey_3.11310,468,908 - 10,478,047 (-)NCBI
UNSW_CanFamBas_1.01310,580,313 - 10,589,461 (-)NCBI
UU_Cfam_GSD_1.01310,669,843 - 10,678,992 (-)NCBI
Kcnv1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530327,686,632 - 27,696,316 (+)NCBI
SpeTri2.0NW_00493647035,113,508 - 35,119,855 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNV1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl427,641,238 - 27,650,054 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1427,640,867 - 27,648,591 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2429,810,564 - 29,817,706 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNV1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18104,656,486 - 104,665,417 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl8104,654,853 - 104,664,699 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603935,896,728 - 35,908,903 (+)NCBIVero_WHO_p1.0
Kcnv1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247639,010,899 - 9,019,857 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247639,013,219 - 9,020,870 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
UniSTS:237292  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381545,108,732 - 45,108,931UniSTSGRCm38
MGSCv371544,940,278 - 44,940,477UniSTSGRCm37
Celera1545,559,536 - 45,559,735UniSTS
Cytogenetic Map15D1UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10401902Sicd2_mseizure-induced cell death 2 (mouse)Not determined15347438971197538Mouse
4141952W3q7_mweight 3 weeks QTL 7 (mouse)Not determined348969478601286Mouse
4142252Tailaq4_mtail length adjusted QTL 4 (mouse)Not determined348969478601286Mouse
4142448Tailq6_mtail length QTL 6 (mouse)Not determined348969478601286Mouse
1357559Scfq2_msubcutaneous fat pad weight QTL 2 (mouse)Not determined15348969478601286Mouse
1357659Epfpq4_mepididymal fat percentage QTL 4 (mouse)Not determined15348969478601286Mouse
26884384Skwq12_mskull length QTL 12, 16 week (mouse)15612948150763396Mouse
26884387Skwq8_mskull length QTL 8, 10 week (mouse)15612948168271849Mouse
26884412Bzwq10_mbi-zygomatic width QTL 10, 10 week (mouse)15612948171471849Mouse
26884417Bzwq4_mbi-zygomatic width QTL 4, 5 week (mouse)15612948172471849Mouse
27226786Feml11_mfemur length 11, 5 week (mouse)15612948175871849Mouse
27095932Ulnl11_mulna length 11, 16 week (mouse)15612948176384200Mouse
27226717Tibw4_mtibia width 4, proximal, 10 week (mouse)15612948178684200Mouse
27226734Tibmd5_mtibia midshaft diameter 5, 10 week (mouse)15612948186684201Mouse
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
26884429Zlq6_mzygomatic length QTL 6, 10 week (mouse)15682948144963396Mouse
27226721Tibw8_mtibia width 8, proximal, 16 week (mouse)15692948175871849Mouse
27226773Tibl16_mtibia length 16, 10 week (mouse)15692948175871849Mouse
27226777Tibl8_mtibia length 8, 5 week (mouse)15692948184584201Mouse
27095940Ulnl8_mulna length 8, 10 week (mouse)15722948155263396Mouse
27226759Feml17_mfemur length 17, 10 week (mouse)15762948155263396Mouse
27226755Feml22_mfemur length 22, 16 week (mouse)15762948159271849Mouse
26884439Sklq11_mskull length QTL 11, 10 week (mouse)15812948447663396Mouse
4141192Ssrq2_mstress response QTL 2 (mouse)Not determined927302256186850Mouse
1301433Rapop5_mradiation-induced apoptosis 5 (mouse)Not determined15927302279474762Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
1301020Pheo_mpheomelanin (mouse)Not determined151384700647847148Mouse
1302165Yv_myellow value (mouse)Not determined151384700647847148Mouse
4141423Nstr2_mnerve sheath tumor resistance QTL 2 (mouse)Not determined1492758748927756Mouse
1301951Eila3_methanol induced locomotor activity 3 (mouse)Not determined151492758748927756Mouse
1302007Bbaa14_mB.burgdorferi-associated arthritis 14 (mouse)Not determined151492758748927756Mouse
1301499Bdln2_mbody length 2 (mouse)Not determined151564534349645470Mouse
12859288Criq1_mCitrobacter rodentium infection QTL 1 (mouse)151603395450033954Mouse
26884423Zlq10_mzygomatic length QTL 10, 16 week (mouse)152060008650763396Mouse
14928313Manh78_mmandible shape 78 (mouse)152148464155484641Mouse
12859289Criq3_mCitrobacter rodentium infection QTL 3 (mouse)152259376556593765Mouse
4142160Femwf10_mfemur work to failure 10 (mouse)Not determined2289301456893160Mouse
1301557Bbaa22_mB.burgdorferi-associated arthritis 22 (mouse)Not determined152446257258462805Mouse
1300967Bdt6_mbone density traits 6 (mouse)Not determined152529580659295928Mouse
4141409Radsvq1_mradiation sensitivity QTL 1 (mouse)Not determined2548497859484978Mouse
1300772Bglq16_mbody growth late QTL 16 (mouse)Not determined152631178060311880Mouse
1301345Bgeq14_mbody growth early QTL 14 (mouse)Not determined152631178060311880Mouse
1357514Mbis3_mMycobacterium bovis-induced systemic lupus erythematosus 3 (mouse)Not determined162631178060311880Mouse
1301406Egrd2_mearly growth rate (mouse)Not determined152631178060311880Mouse
27226800Scvln20_msacral vertebrae length 2, 16 week (mouse)152660008666371849Mouse
1301450Bpq6_mblood pressure QTL 6 (mouse)Not determined152828264662282739Mouse
1357512Bsbob5_mBSB obesity 5 (mouse)Not determined152828264662282739Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
26884392Humsd8_mhumerus midshaft diameter 8, 16 week (mouse)152930014676084200Mouse
26884452Sklq17_mskull length QTL 17, 16 week (mouse)153020014657963396Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
1300578Cd8ts3_mCD8 T cell subset 3 (mouse)Not determined153400469468004804Mouse
1301324Cdif_mcolor difference (mouse)Not determined153597590669976019Mouse
27226729Tibmd2_mtibia midshaft diameter 2, 5 week (mouse)153800024486684201Mouse
12792977Tbmd1_mtibial bone mineral density 1, males only (mouse)153807048952031841Mouse
1301580Hrq2_mheart rate quantitative locus 2 (mouse)Not determined153910039573100593Mouse
1300949Lore5_mloss of righting induced by ethanol 5 (mouse)Not determined154001944158022297Mouse
4142459Lfnq3_mlung function QTL 3 (mouse)Not determined4017702272372580Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
1357703Vtbt17_mvertebral trabecular bone trait 17 (mouse)Not determined154455331378553437Mouse
1301568Tria2_mT-cell receptor induced activation 2 (mouse)Not determined154485914178859281Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:931
Count of miRNA genes:473
Interacting mature miRNAs:578
Transcripts:ENSMUST00000022967
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000022967   ⟹   ENSMUSP00000022967
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1544,969,680 - 44,978,223 (-)Ensembl
GRCm38.p6 Ensembl1545,106,284 - 45,114,827 (-)Ensembl
RefSeq Acc Id: ENSMUST00000228536
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1544,976,181 - 44,978,316 (-)Ensembl
GRCm38.p6 Ensembl1545,112,785 - 45,114,920 (-)Ensembl
RefSeq Acc Id: NM_026200   ⟹   NP_080476
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391544,969,680 - 44,978,330 (-)NCBI
GRCm381545,106,284 - 45,114,934 (-)NCBI
MGSCv371544,937,830 - 44,946,480 (-)RGD
Celera1545,557,088 - 45,565,718 (-)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006521297   ⟹   XP_006521360
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391544,959,482 - 44,979,375 (-)NCBI
GRCm381545,096,086 - 45,115,912 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_080476   ⟸   NM_026200
- UniProtKB: Q8BZN2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006521360   ⟸   XM_006521297
- Peptide Label: isoform X1
- UniProtKB: Q8BZN2 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000022967   ⟸   ENSMUST00000022967

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BZN2-F1-model_v2 AlphaFold Q8BZN2 1-503 view protein structure

Promoters
RGD ID:6826120
Promoter ID:MM_KWN:18391
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:NM_026200,   UC007VQM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361544,945,761 - 44,946,261 (-)MPROMDB
RGD ID:8683708
Promoter ID:EPDNEW_M19884
Type:initiation region
Name:Kcnv1_1
Description:Mus musculus potassium channel, subfamily V, member 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381545,114,902 - 45,114,962EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1914748 AgrOrtholog
Ensembl Genes ENSMUSG00000022342 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000022967 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022967 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.120.350 UniProtKB/Swiss-Prot
  3.30.710.10 UniProtKB/Swiss-Prot
InterPro BTB/POZ_dom UniProtKB/Swiss-Prot
  Ion_trans_dom UniProtKB/Swiss-Prot
  K_chnl_volt-dep_Kv UniProtKB/Swiss-Prot
  K_chnl_volt-dep_Kv8.1 UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
  T1-type_BTB UniProtKB/Swiss-Prot
  VG_K_chnl UniProtKB/Swiss-Prot
  Volt_channel_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:67498 UniProtKB/Swiss-Prot
MGD MGI:1914748 ENTREZGENE
NCBI Gene 67498 ENTREZGENE
PANTHER PTHR11537 UniProtKB/Swiss-Prot
  PTHR11537:SF38 UniProtKB/Swiss-Prot
Pfam BTB_2 UniProtKB/Swiss-Prot
  Ion_trans UniProtKB/Swiss-Prot
PhenoGen Kcnv1 PhenoGen
PRINTS KV8CHANNEL UniProtKB/Swiss-Prot
  KVCHANNEL UniProtKB/Swiss-Prot
SMART BTB UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54695 UniProtKB/Swiss-Prot
UniProt KCNV1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8BK61 UniProtKB/Swiss-Prot
  Q8BYS7 UniProtKB/Swiss-Prot
  Q9CZR1 UniProtKB/Swiss-Prot