Mdm2 Mouse (+)-catechin decreases expression ISO MDM2 (Homo sapiens) 6480464 Catechin results in decreased expression of MDM2 mRNA CTD PMID:23706674 Mdm2 Mouse (+)-schisandrin B multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MDM2 mRNA] CTD PMID:31150632 Mdm2 Mouse (-)-demecolcine increases expression ISO MDM2 (Homo sapiens) 6480464 Demecolcine results in increased expression of MDM2 mRNA CTD PMID:23649840 Mdm2 Mouse (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in more ... CTD PMID:23717041 Mdm2 Mouse (S)-naringenin multiple interactions ISO MDM2 (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of MDM2 mRNA; [naringenin metabolite co-treated more ... CTD PMID:36235125 Mdm2 Mouse (S)-naringenin increases expression ISO MDM2 (Homo sapiens) 6480464 naringenin metabolite results in increased expression of MDM2 mRNA CTD PMID:36235125 Mdm2 Mouse (S)-nicotine multiple interactions ISO MDM2 (Homo sapiens) 6480464 [[Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 more ... CTD PMID:30272249 Mdm2 Mouse 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression EXP 6480464 o,p'-DDT affects the expression of MDM2 mRNA CTD PMID:18925944 Mdm2 Mouse 1,10-phenanthroline increases expression ISO MDM2 (Homo sapiens) 6480464 1,10-phenanthroline results in increased expression of MDM2 mRNA CTD PMID:19502547 Mdm2 Mouse 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,4,5,2',5'-pentachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709|PMID:20840854 Mdm2 Mouse 1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactions ISO MDM2 (Homo sapiens) 6480464 2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; MDM2 mutant form more ... CTD PMID:20840854 Mdm2 Mouse 1,2-dimethylhydrazine multiple interactions EXP 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of MDM2 mRNA CTD PMID:22206623 Mdm2 Mouse 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Citalopram results in increased expression of MDM2 mRNA CTD PMID:28467792 Mdm2 Mouse 1-nitropyrene increases expression ISO MDM2 (Homo sapiens) 6480464 1-nitropyrene results in increased expression of MDM2 mRNA; 1-nitropyrene results in increased expression of MDM2 more ... CTD PMID:10837373|PMID:22044530 Mdm2 Mouse 1-nitropyrene multiple interactions ISO MDM2 (Homo sapiens) 6480464 nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein more ... CTD PMID:10837373|PMID:22044530 Mdm2 Mouse 10-Hydroxycamptothecin affects response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 protein affects the susceptibility to 10-hydroxycamptothecin CTD PMID:13130078 Mdm2 Mouse 17alpha-ethynylestradiol increases expression ISO MDM2 (Homo sapiens) 6480464 Ethinyl Estradiol results in increased expression of MDM2 mRNA alternative form; Ethinyl Estradiol results in more ... CTD PMID:12168835 Mdm2 Mouse 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of MDM2 mRNA CTD PMID:17942748 Mdm2 Mouse 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNA CTD PMID:17942748 Mdm2 Mouse 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of MDM2 mRNA CTD PMID:17555576 Mdm2 Mouse 17beta-estradiol increases expression ISO MDM2 (Homo sapiens) 6480464 Estradiol results in increased expression of MDM2 mRNA alternative form; Estradiol results in increased expression more ... CTD PMID:12168835 Mdm2 Mouse 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of MDM2 mRNA; Estradiol results in increased expression of MDM2 more ... CTD PMID:23684557 Mdm2 Mouse 17beta-estradiol multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Estradiol co-treated with Parathion] results in increased expression of MDM2 mRNA; [Estradiol co-treated with TGFB1 more ... CTD PMID:17622325|PMID:30165855 Mdm2 Mouse 17beta-estradiol decreases phosphorylation EXP 6480464 Estradiol results in decreased phosphorylation of MDM2 protein CTD PMID:22314386 Mdm2 Mouse 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one increases expression ISO MDM2 (Homo sapiens) 6480464 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one results in increased expression of MDM2 protein CTD PMID:16288207 Mdm2 Mouse 2,2',3,3',6,6'-hexachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,3,6,2',3',6'-hexachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO MDM2 (Homo sapiens) 6480464 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein] CTD PMID:20840854 Mdm2 Mouse 2,2',4,4',5,5'-hexachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,4,5,2',4',5'-hexachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709|PMID:20840854 Mdm2 Mouse 2,2',4,4'-tetrachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,4,2',4'-tetrachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse 2,2',4,5-tetrachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,4,4',5-tetrachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse 2,2',5,5'-tetrachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,5,2',5'-tetrachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one increases expression ISO MDM2 (Homo sapiens) 6480464 2,2-bis(hydroxymethyl)-1-azabicyclo(2,2,2,)octan-3-one results in increased expression of MDM2 CTD PMID:21647879 Mdm2 Mouse 2,3,3',4,4',5,5'-Heptachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,2',3,3',4,4',5-heptachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO MDM2 (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of more ... CTD PMID:19578757|PMID:22044530 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA CTD PMID:33387578 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA CTD PMID:12167310|PMID:21041162|PMID:26290441 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of MDM2 mRNA CTD PMID:21570461 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 protein CTD PMID:15459018 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein]; Tetrachlorodibenzodioxin results in more ... CTD PMID:15459018 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases degradation ISO Mdm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased degradation of MDM2 protein CTD PMID:15459018 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNA CTD PMID:17942748 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO MDM2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA CTD PMID:19578757 Mdm2 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO MDM2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of MDM2 mRNA CTD PMID:16039398 Mdm2 Mouse 2,4,4'-trichlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,4,4'-trichlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709|PMID:20840854 Mdm2 Mouse 2,4,4'-trichlorobiphenyl multiple interactions ISO MDM2 (Homo sapiens) 6480464 2,4,4'-trichlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein] CTD PMID:20840854 Mdm2 Mouse 2,4-dinitrotoluene affects expression ISO Mdm2 (Rattus norvegicus) 6480464 2,4-dinitrotoluene affects the expression of MDM2 mRNA CTD PMID:21346803 Mdm2 Mouse 2,6-dinitrotoluene affects expression ISO Mdm2 (Rattus norvegicus) 6480464 2,6-dinitrotoluene affects the expression of MDM2 mRNA CTD PMID:21346803 Mdm2 Mouse 2-acetamidofluorene multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein CTD PMID:11003613 Mdm2 Mouse 2-acetamidofluorene increases expression ISO Mdm2 (Rattus norvegicus) 6480464 2-Acetylaminofluorene results in increased expression of MDM2 mRNA; 2-Acetylaminofluorene results in increased expression of MDM2 more ... CTD PMID:19167416|PMID:22213190|PMID:22584684 Mdm2 Mouse 2-acetamidofluorene increases expression EXP 6480464 2-Acetylaminofluorene results in increased expression of MDM2 mRNA CTD PMID:21607683 Mdm2 Mouse 2-nitrofluorene increases expression ISO Mdm2 (Rattus norvegicus) 6480464 2-nitrofluorene results in increased expression of MDM2 mRNA CTD PMID:14600272|PMID:15890375|PMID:22484513|PMID:23052194 Mdm2 Mouse 3,3',4,4',5-pentachlorobiphenyl increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709|PMID:20840854 Mdm2 Mouse 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO MDM2 (Homo sapiens) 6480464 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; MDM2 mutant form more ... CTD PMID:20840854 Mdm2 Mouse 3,3'-diindolylmethane decreases expression EXP 6480464 3,3'-diindolylmethane analog results in decreased expression of MDM2 mRNA CTD PMID:26593444 Mdm2 Mouse 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine increases expression ISO MDM2 (Homo sapiens) 6480464 3,4,8-trimethylimidazo(4,5-f)quinoxalin-2-amine results in increased expression of MDM2 mRNA CTD PMID:23810796 Mdm2 Mouse 3-phenylprop-2-enal increases expression ISO MDM2 (Homo sapiens) 6480464 cinnamaldehyde results in increased expression of MDM2 mRNA CTD PMID:19000754 Mdm2 Mouse 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4,4'-diaminodiphenylmethane results in increased expression of MDM2 mRNA CTD PMID:18648102 Mdm2 Mouse 4,4'-sulfonyldiphenol increases methylation EXP 6480464 bisphenol S results in increased methylation of MDM2 promoter CTD PMID:33297965 Mdm2 Mouse 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of MDM2 mRNA CTD PMID:39298647 Mdm2 Mouse 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO Mdm2 (Rattus norvegicus) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA CTD PMID:14600272|PMID:15890375|PMID:22484513|PMID:23052194 Mdm2 Mouse 4-hydroperoxycyclophosphamide increases expression ISO MDM2 (Homo sapiens) 6480464 perfosfamide results in increased expression of MDM2 CTD PMID:18034189 Mdm2 Mouse 4-hydroxyphenyl retinamide decreases expression ISO MDM2 (Homo sapiens) 6480464 Fenretinide results in decreased expression of MDM2 mRNA CTD PMID:16570282 Mdm2 Mouse 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of MDM2 mRNA CTD PMID:28973697 Mdm2 Mouse 5-aza-2'-deoxycytidine affects expression ISO MDM2 (Homo sapiens) 6480464 Decitabine affects the expression of MDM2 mRNA CTD PMID:17145863 Mdm2 Mouse 5-azacytidine increases expression ISO MDM2 (Homo sapiens) 6480464 Azacitidine results in increased expression of MDM2 mRNA CTD PMID:20823114 Mdm2 Mouse 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of MDM2 mRNA CTD PMID:16949053 Mdm2 Mouse 5-fluorouracil increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Fluorouracil results in increased phosphorylation of MDM2 protein CTD PMID:25744307 Mdm2 Mouse 5-fluorouracil increases expression ISO MDM2 (Homo sapiens) 6480464 Fluorouracil results in increased expression of MDM2 mRNA; Fluorouracil results in increased expression of MDM2 more ... CTD PMID:14665630|PMID:15546879|PMID:16557594|PMID:17982676|PMID:18096571|PMID:19098008|PMID:22525470|PMID:28785074|PMID:30177839 Mdm2 Mouse 5-fluorouracil multiple interactions ISO MDM2 (Homo sapiens) 6480464 Cadmium Chloride affects the reaction [Fluorouracil results in increased phosphorylation of MDM2 protein]; Fluorouracil promotes more ... CTD PMID:15546879|PMID:17982676|PMID:25744307 Mdm2 Mouse 7,12-dimethyltetraphene increases expression EXP 6480464 9,10-Dimethyl-1,2-benzanthracene metabolite results in increased expression of MDM2 mRNA; 9,10-Dimethyl-1,2-benzanthracene results in increased expression of more ... CTD PMID:23717041|PMID:32553695 Mdm2 Mouse 7,12-dimethyltetraphene multiple interactions EXP 6480464 [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in more ... CTD PMID:23717041 Mdm2 Mouse acetamide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 acetamide results in increased expression of MDM2 mRNA CTD PMID:31881176 Mdm2 Mouse acetylsalicylic acid decreases expression ISO MDM2 (Homo sapiens) 6480464 Aspirin results in decreased expression of MDM2 mRNA CTD PMID:20457246 Mdm2 Mouse actinomycin D multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of MDM2 mRNA; [Dactinomycin co-treated with more ... CTD PMID:38460933 Mdm2 Mouse actinomycin D increases expression ISO MDM2 (Homo sapiens) 6480464 Dactinomycin results in increased expression of MDM2 mRNA CTD PMID:38460933 Mdm2 Mouse adefovir pivoxil increases expression ISO MDM2 (Homo sapiens) 6480464 adefovir dipivoxil results in increased expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse aflatoxin B1 affects expression ISO MDM2 (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of MDM2 protein CTD PMID:20106945 Mdm2 Mouse aflatoxin B1 increases expression ISO MDM2 (Homo sapiens) 6480464 Aflatoxin B1 results in increased expression of MDM2 mRNA CTD PMID:21632981|PMID:21641981|PMID:27153756|PMID:29445054|PMID:31555880|PMID:32234424 Mdm2 Mouse aflatoxin B1 decreases methylation ISO MDM2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of MDM2 gene CTD PMID:27153756 Mdm2 Mouse aflatoxin B1 increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of MDM2 mRNA CTD PMID:14600272|PMID:15890375|PMID:22484513|PMID:23052194|PMID:23630614|PMID:25378103|PMID:33354967 Mdm2 Mouse aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of MDM2 mRNA CTD PMID:19770486 Mdm2 Mouse aflatoxin M1 decreases expression ISO MDM2 (Homo sapiens) 6480464 Aflatoxin M1 results in decreased expression of MDM2 mRNA CTD PMID:30928695 Mdm2 Mouse alpha-naphthoflavone multiple interactions ISO MDM2 (Homo sapiens) 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of more ... CTD PMID:19578757 Mdm2 Mouse alvocidib decreases expression ISO MDM2 (Homo sapiens) 6480464 alvocidib results in decreased expression of MDM2 mRNA; alvocidib results in decreased expression of MDM2 more ... CTD PMID:12589031 Mdm2 Mouse amifostine decreases expression ISO MDM2 (Homo sapiens) 6480464 Amifostine results in decreased expression of MDM2 mRNA CTD PMID:14555708 Mdm2 Mouse amitrole decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Amitrole results in decreased expression of MDM2 mRNA CTD PMID:38685447 Mdm2 Mouse ammonium chloride increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Ammonium Chloride results in increased expression of MDM2 mRNA; Ammonium Chloride results in increased expression more ... CTD PMID:12420312|PMID:16483693 Mdm2 Mouse amphetamine increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Amphetamine results in increased expression of MDM2 mRNA CTD PMID:30779732 Mdm2 Mouse amphibole asbestos decreases expression ISO MDM2 (Homo sapiens) 6480464 Asbestos, Amphibole results in decreased expression of MDM2 protein CTD PMID:20855422 Mdm2 Mouse amsacrine decreases response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 promoter SNP results in decreased susceptibility to Amsacrine CTD PMID:17575151 Mdm2 Mouse androstane multiple interactions EXP 6480464 Androstanols inhibits the reaction [DDT results in increased expression of MDM2 mRNA] CTD PMID:23684557 Mdm2 Mouse antimycin A increases expression ISO MDM2 (Homo sapiens) 6480464 Antimycin A results in increased expression of MDM2 mRNA CTD PMID:33512557 Mdm2 Mouse arsane affects response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 SNP affects the susceptibility to Arsenic CTD PMID:21982800 Mdm2 Mouse arsane multiple interactions ISO MDM2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MDM2 more ... CTD PMID:35821281|PMID:39836092 Mdm2 Mouse arsane increases expression ISO MDM2 (Homo sapiens) 6480464 Arsenic results in increased expression of MDM2 protein CTD PMID:35821281 Mdm2 Mouse arsane affects methylation ISO MDM2 (Homo sapiens) 6480464 Arsenic affects the methylation of MDM2 gene CTD PMID:25304211 Mdm2 Mouse arsenic atom affects response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 SNP affects the susceptibility to Arsenic CTD PMID:21982800 Mdm2 Mouse arsenic atom multiple interactions ISO MDM2 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MDM2 more ... CTD PMID:35821281|PMID:39836092 Mdm2 Mouse arsenic atom increases expression ISO MDM2 (Homo sapiens) 6480464 Arsenic results in increased expression of MDM2 protein CTD PMID:35821281 Mdm2 Mouse arsenic atom affects methylation ISO MDM2 (Homo sapiens) 6480464 Arsenic affects the methylation of MDM2 gene CTD PMID:25304211 Mdm2 Mouse arsenite(3-) multiple interactions ISO MDM2 (Homo sapiens) 6480464 [[[arsenite results in increased activity of PRKDC protein] which results in increased phosphorylation of and more ... CTD PMID:22366412|PMID:30177839|PMID:32406909 Mdm2 Mouse arsenite(3-) increases expression ISO MDM2 (Homo sapiens) 6480464 arsenite results in increased expression of MDM2 mRNA; arsenite results in increased expression of MDM2 more ... CTD PMID:30177839|PMID:34425169 Mdm2 Mouse arsenous acid decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Arsenic Trioxide results in decreased expression of MDM2 mRNA CTD PMID:21145380 Mdm2 Mouse arsenous acid increases expression ISO MDM2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of MDM2 mRNA CTD PMID:20862710|PMID:25574600|PMID:26705709 Mdm2 Mouse arsenous acid multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA] CTD PMID:17487067 Mdm2 Mouse arsenous acid decreases expression ISO MDM2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of MDM2 mRNA CTD PMID:20458559 Mdm2 Mouse arsenous acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of MDM2 mRNA CTD PMID:17487067 Mdm2 Mouse aspartame multiple interactions EXP 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MDM2 mRNA CTD PMID:23783067 Mdm2 Mouse atorvastatin calcium increases expression ISO MDM2 (Homo sapiens) 6480464 Atorvastatin results in increased expression of MDM2 protein CTD PMID:29630879 Mdm2 Mouse atrazine affects methylation ISO Mdm2 (Rattus norvegicus) 6480464 Atrazine affects the methylation of MDM2 gene CTD PMID:28931070|PMID:35440735 Mdm2 Mouse avobenzone increases expression ISO MDM2 (Homo sapiens) 6480464 avobenzone results in increased expression of MDM2 mRNA CTD PMID:31016361 Mdm2 Mouse azoxystrobin increases expression ISO MDM2 (Homo sapiens) 6480464 azoxystrobin results in increased expression of MDM2 protein CTD PMID:32339800 Mdm2 Mouse benzene multiple interactions EXP 6480464 TRP53 protein affects the reaction [Benzene results in increased expression of MDM2 mRNA] CTD PMID:11896287 Mdm2 Mouse benzene increases expression EXP 6480464 Benzene results in increased expression of MDM2 mRNA CTD PMID:11896287|PMID:15342939|PMID:15935812 Mdm2 Mouse benzene multiple interactions ISO MDM2 (Homo sapiens) 6480464 MDM2 gene polymorphism affects the reaction [CDKN2A gene polymorphism affects the susceptibility to Benzene] CTD PMID:19596022 Mdm2 Mouse benzene multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA CTD PMID:17905399 Mdm2 Mouse benzo[a]pyrene increases expression ISO MDM2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of MDM2 mRNA; Benzo(a)pyrene results in increased expression of MDM2 more ... CTD PMID:10837373|PMID:18418871|PMID:20106945|PMID:21632981|PMID:21871943|PMID:22044530|PMID:22316170|PMID:22889811|PMID:25690898|PMID:26238291|PMID:27694624|PMID:28461126|PMID:30562542|PMID:31555880|PMID:32234424 Mdm2 Mouse benzo[a]pyrene decreases expression ISO MDM2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of MDM2 mRNA CTD PMID:30562542 Mdm2 Mouse benzo[a]pyrene increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased phosphorylation of MDM2 protein CTD PMID:20840854|PMID:25744307 Mdm2 Mouse benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene metabolite results in increased expression of MDM2 mRNA; Benzo(a)pyrene results in increased expression of more ... CTD PMID:18656336|PMID:19146932|PMID:19770486|PMID:21569818|PMID:22228805|PMID:22610609|PMID:23735875|PMID:32553695|PMID:9006915 Mdm2 Mouse benzo[a]pyrene decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in decreased expression of MDM2 protein CTD PMID:21467743 Mdm2 Mouse benzo[a]pyrene multiple interactions ISO MDM2 (Homo sapiens) 6480464 2,4,4'-trichlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MDM2 protein]; 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the more ... CTD PMID:10837373|PMID:15625077|PMID:17690111|PMID:18096571|PMID:20840854|PMID:25744307 Mdm2 Mouse benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Mdm2 Mouse benzo[a]pyrene diol epoxide I increases expression ISO MDM2 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MDM2 mRNA CTD PMID:20382639|PMID:26238291|PMID:28593498 Mdm2 Mouse benzo[a]pyrene diol epoxide I increases expression EXP 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of MDM2 mRNA CTD PMID:39826883 Mdm2 Mouse benzo[b]fluoranthene increases expression EXP 6480464 benzo(b)fluoranthene results in increased expression of MDM2 mRNA CTD PMID:26377693 Mdm2 Mouse benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Mdm2 Mouse beta-naphthoflavone increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 beta-Naphthoflavone results in increased phosphorylation of MDM2 protein CTD PMID:26558467 Mdm2 Mouse biphenyl-4-amine multiple interactions ISO MDM2 (Homo sapiens) 6480464 TP53 protein inhibits the reaction [4-biphenylamine results in increased expression of MDM2 mRNA] CTD PMID:32905825 Mdm2 Mouse biphenyl-4-amine increases expression ISO MDM2 (Homo sapiens) 6480464 4-biphenylamine results in increased expression of MDM2 mRNA CTD PMID:32905825 Mdm2 Mouse bis(2-chloroethyl) sulfide affects expression ISO Mdm2 (Rattus norvegicus) 6480464 Mustard Gas affects the expression of MDM2 mRNA CTD PMID:15651846 Mdm2 Mouse bis(2-chloroethyl) sulfide increases expression ISO MDM2 (Homo sapiens) 6480464 Mustard Gas results in increased expression of MDM2 mRNA CTD PMID:33491125 Mdm2 Mouse bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of MDM2 mRNA CTD PMID:15674843|PMID:18955075 Mdm2 Mouse bis(2-ethylhexyl) phthalate decreases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in decreased phosphorylation of MDM2 protein CTD PMID:31163220 Mdm2 Mouse bis(2-ethylhexyl) phthalate increases expression ISO MDM2 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of MDM2 mRNA CTD PMID:31163220 Mdm2 Mouse bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of MDM2 mRNA CTD PMID:26063408 Mdm2 Mouse bisphenol A increases expression ISO Mdm2 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of MDM2 mRNA CTD PMID:30816183|PMID:32528016|PMID:34947998 Mdm2 Mouse bisphenol A affects expression ISO MDM2 (Homo sapiens) 6480464 bisphenol A affects the expression of MDM2 mRNA CTD PMID:30903817 Mdm2 Mouse bisphenol A increases expression ISO MDM2 (Homo sapiens) 6480464 bisphenol A analog results in increased expression of MDM2 mRNA; bisphenol A results in increased more ... CTD PMID:29275510|PMID:32387340 Mdm2 Mouse bisphenol A multiple interactions ISO MDM2 (Homo sapiens) 6480464 [naringenin co-treated with bisphenol A] results in increased expression of MDM2 mRNA; [naringenin metabolite co-treated more ... CTD PMID:24831732|PMID:36235125 Mdm2 Mouse bisphenol A increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 bisphenol A results in increased phosphorylation of MDM2 protein CTD PMID:24831732 Mdm2 Mouse bisphenol A affects expression ISO Mdm2 (Rattus norvegicus) 6480464 bisphenol A affects the expression of MDM2 mRNA CTD PMID:25181051 Mdm2 Mouse bisphenol A decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of MDM2 mRNA CTD PMID:26982218 Mdm2 Mouse bisphenol AF multiple interactions ISO MDM2 (Homo sapiens) 6480464 [bisphenol AF co-treated with cylindrospermopsin] results in increased expression of MDM2 mRNA CTD PMID:32244372 Mdm2 Mouse bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of MDM2 mRNA CTD PMID:35387338 Mdm2 Mouse bortezomib multiple interactions ISO MDM2 (Homo sapiens) 6480464 [CASP8 protein results in increased activity of CASP3 protein] affects the reaction [Bortezomib results in more ... CTD PMID:12393500 Mdm2 Mouse bortezomib increases cleavage ISO MDM2 (Homo sapiens) 6480464 Bortezomib results in increased cleavage of MDM2 protein CTD PMID:12393500 Mdm2 Mouse bortezomib affects expression ISO MDM2 (Homo sapiens) 6480464 Bortezomib affects the expression of MDM2 protein CTD PMID:12393500 Mdm2 Mouse brassinolide decreases expression ISO MDM2 (Homo sapiens) 6480464 brassinolide results in decreased expression of MDM2 protein CTD PMID:20833159 Mdm2 Mouse cadmium acetate increases expression ISO MDM2 (Homo sapiens) 6480464 cadmium acetate results in increased expression of MDM2 protein CTD PMID:15450950 Mdm2 Mouse cadmium atom decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Cadmium results in decreased expression of MDM2 mRNA CTD PMID:21467746 Mdm2 Mouse cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of MDM2 mRNA CTD PMID:22666406 Mdm2 Mouse cadmium dichloride affects expression ISO Mdm2 (Rattus norvegicus) 6480464 Cadmium Chloride affects the expression of MDM2 mRNA CTD PMID:22110744 Mdm2 Mouse cadmium dichloride decreases expression ISO MDM2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of MDM2 mRNA CTD PMID:38568856 Mdm2 Mouse cadmium dichloride multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of MDM2 mRNA CTD PMID:31077537 Mdm2 Mouse cadmium dichloride decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of MDM2 mRNA CTD PMID:31077537 Mdm2 Mouse cadmium dichloride increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of MDM2 mRNA CTD PMID:23405080 Mdm2 Mouse cadmium dichloride increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Cadmium Chloride results in increased phosphorylation of MDM2 protein CTD PMID:25744307 Mdm2 Mouse cadmium dichloride multiple interactions ISO MDM2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MDM2 protein]; Cadmium Chloride more ... CTD PMID:25744307 Mdm2 Mouse cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of MDM2 mRNA CTD PMID:11958953|PMID:20061341|PMID:22314386 Mdm2 Mouse cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of MDM2 protein CTD PMID:20525538|PMID:22314386 Mdm2 Mouse cadmium dichloride multiple interactions EXP 6480464 Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein]; MT1 affects more ... CTD PMID:11958953|PMID:12135628 Mdm2 Mouse caffeine decreases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of MDM2 protein CTD PMID:35688186 Mdm2 Mouse camptothecin increases expression ISO MDM2 (Homo sapiens) 6480464 Camptothecin results in increased expression of MDM2 protein CTD PMID:17555331 Mdm2 Mouse cannabidiol increases expression EXP 6480464 Cannabidiol results in increased expression of MDM2 mRNA CTD PMID:30742662 Mdm2 Mouse cannabidiol increases expression ISO MDM2 (Homo sapiens) 6480464 Cannabidiol results in increased expression of MDM2 mRNA CTD PMID:27932991|PMID:30713602 Mdm2 Mouse cannabidiol multiple interactions EXP 6480464 [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MDM2 mRNA CTD PMID:30742662 Mdm2 Mouse cantharidin decreases expression ISO MDM2 (Homo sapiens) 6480464 Cantharidin results in decreased expression of MDM2 mRNA CTD PMID:31945315 Mdm2 Mouse capsaicin multiple interactions ISO MDM2 (Homo sapiens) 6480464 Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein]; resveratrol promotes the more ... CTD PMID:19846903 Mdm2 Mouse capsaicin increases expression ISO MDM2 (Homo sapiens) 6480464 Capsaicin results in increased expression of MDM2 mRNA CTD PMID:19502594 Mdm2 Mouse capsaicin decreases expression ISO MDM2 (Homo sapiens) 6480464 Capsaicin results in decreased expression of MDM2 protein CTD PMID:19846903 Mdm2 Mouse Carbadox increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Carbadox results in increased expression of MDM2 mRNA CTD PMID:26558467 Mdm2 Mouse carbamazepine affects expression ISO MDM2 (Homo sapiens) 6480464 Carbamazepine affects the expression of MDM2 mRNA CTD PMID:25979313 Mdm2 Mouse carbonyl cyanide p-trifluoromethoxyphenylhydrazone decreases expression ISO MDM2 (Homo sapiens) 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA CTD PMID:16039398 Mdm2 Mouse chlorambucil increases expression ISO MDM2 (Homo sapiens) 6480464 Chlorambucil results in increased expression of MDM2 mRNA CTD PMID:17476690 Mdm2 Mouse chloroacetaldehyde increases expression ISO MDM2 (Homo sapiens) 6480464 chloroacetaldehyde results in increased expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse chloroethene affects response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 polymorphism affects the susceptibility to Vinyl Chloride CTD PMID:24464562 Mdm2 Mouse chloroprene increases expression EXP 6480464 Chloroprene results in increased expression of MDM2 mRNA CTD PMID:23125180 Mdm2 Mouse chlorpromazine increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Chlorpromazine results in increased expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse chlorpyrifos increases expression ISO MDM2 (Homo sapiens) 6480464 Chlorpyrifos results in increased expression of MDM2 mRNA CTD PMID:30981936 Mdm2 Mouse chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of MDM2 mRNA CTD PMID:37019170 Mdm2 Mouse choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... CTD PMID:20938992 Mdm2 Mouse chrysene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Mdm2 Mouse cidofovir anhydrous affects expression ISO MDM2 (Homo sapiens) 6480464 Cidofovir affects the expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse cisplatin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of MDM2 mRNA CTD PMID:24880025 Mdm2 Mouse cisplatin multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Cisplatin promotes the reaction [NFE2L2 protein results in increased expression of MDM2 mRNA]; NFE2L2 protein more ... CTD PMID:35842499 Mdm2 Mouse cisplatin decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of MDM2 mRNA; Cisplatin results in decreased expression of MDM2 more ... CTD PMID:35842499 Mdm2 Mouse cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of MDM2 mRNA; Cisplatin results in increased expression of MDM2 more ... CTD PMID:21151649|PMID:24280081|PMID:25270620|PMID:32856486|PMID:35842499 Mdm2 Mouse cisplatin multiple interactions EXP 6480464 Cisplatin promotes the reaction [TRP53 protein results in increased expression of MDM2]; NFE2L2 protein affects more ... CTD PMID:21552291|PMID:32856486|PMID:35842499 Mdm2 Mouse cisplatin increases expression ISO MDM2 (Homo sapiens) 6480464 Cisplatin results in increased expression of MDM2 mRNA; Cisplatin results in increased expression of MDM2 more ... CTD PMID:16797627|PMID:24280081|PMID:25450742|PMID:25596134|PMID:32856486|PMID:33545341|PMID:38498338 Mdm2 Mouse cisplatin multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Cisplatin co-treated with eprenetapopt co-treated with Oxygen deficiency] results in increased expression of MDM2 mRNA; more ... CTD PMID:21509038|PMID:21552291|PMID:21624110|PMID:29690507|PMID:32856486 Mdm2 Mouse citalopram increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Citalopram results in increased expression of MDM2 mRNA CTD PMID:28467792 Mdm2 Mouse clofibrate multiple interactions EXP 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA; PPARA affects the reaction [[Clofibrate more ... CTD PMID:17585979 Mdm2 Mouse cobalt atom increases expression ISO MDM2 (Homo sapiens) 6480464 Cobalt results in increased expression of MDM2 mRNA CTD PMID:24068677 Mdm2 Mouse cobalt atom multiple interactions ISO MDM2 (Homo sapiens) 6480464 TP53 protein affects the reaction [Cobalt results in increased expression of MDM2 mRNA] CTD PMID:24068677 Mdm2 Mouse cobalt dichloride increases expression ISO MDM2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of MDM2 protein CTD PMID:19714248 Mdm2 Mouse cobalt dichloride increases expression ISO Mdm2 (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of MDM2 mRNA CTD PMID:24386269 Mdm2 Mouse cobalt dichloride multiple interactions ISO MDM2 (Homo sapiens) 6480464 MDM2 protein promotes the reaction [cobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction more ... CTD PMID:19714248 Mdm2 Mouse copper atom increases expression EXP 6480464 Copper results in increased expression of MDM2 mRNA CTD PMID:16629173 Mdm2 Mouse copper atom multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of MDM2 mRNA CTD PMID:30911355 Mdm2 Mouse copper(0) increases expression EXP 6480464 Copper results in increased expression of MDM2 mRNA CTD PMID:16629173 Mdm2 Mouse copper(0) multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of MDM2 mRNA CTD PMID:30911355 Mdm2 Mouse corn oil decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Corn Oil results in decreased expression of MDM2 mRNA CTD PMID:22760963 Mdm2 Mouse coumarin decreases expression ISO MDM2 (Homo sapiens) 6480464 coumarin analog results in decreased expression of MDM2 mRNA CTD PMID:32578917 Mdm2 Mouse crocidolite asbestos decreases expression EXP 6480464 Asbestos, Crocidolite results in decreased expression of MDM2 mRNA CTD PMID:29279043 Mdm2 Mouse cryptolepine increases expression ISO MDM2 (Homo sapiens) 6480464 cryptolepine results in increased expression of MDM2 mRNA; cryptolepine results in increased expression of MDM2 more ... CTD PMID:16120219 Mdm2 Mouse curcumin decreases expression ISO MDM2 (Homo sapiens) 6480464 [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A more ... CTD PMID:17332326 Mdm2 Mouse curcumin increases expression ISO MDM2 (Homo sapiens) 6480464 Curcumin analog results in increased expression of MDM2 mRNA CTD PMID:26409325 Mdm2 Mouse curcumin multiple interactions ISO MDM2 (Homo sapiens) 6480464 Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of MDM2 protein] CTD PMID:24831732 Mdm2 Mouse cyclosporin A increases expression ISO MDM2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of MDM2 mRNA CTD PMID:20106945|PMID:25562108|PMID:25596134 Mdm2 Mouse cylindrospermopsin increases expression ISO MDM2 (Homo sapiens) 6480464 cylindrospermopsin results in increased expression of MDM2 mRNA CTD PMID:21607682 Mdm2 Mouse cylindrospermopsin multiple interactions ISO MDM2 (Homo sapiens) 6480464 [bisphenol AF co-treated with cylindrospermopsin] results in increased expression of MDM2 mRNA CTD PMID:32244372 Mdm2 Mouse cyproconazole multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of MDM2 mRNA; [cyproconazole more ... CTD PMID:29038839 Mdm2 Mouse DAPT multiple interactions ISO MDM2 (Homo sapiens) 6480464 Hydrogen Peroxide inhibits the reaction [N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in increased expression of MDM2 protein] CTD PMID:25005833 Mdm2 Mouse DAPT increases expression ISO MDM2 (Homo sapiens) 6480464 N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in increased expression of MDM2 protein CTD PMID:25005833 Mdm2 Mouse DDT multiple interactions EXP 6480464 Androstanols inhibits the reaction [DDT results in increased expression of MDM2 mRNA] CTD PMID:23684557 Mdm2 Mouse DDT increases expression EXP 6480464 DDT results in increased expression of MDM2 mRNA; DDT results in increased expression of MDM2 more ... CTD PMID:23684557 Mdm2 Mouse deguelin increases expression ISO MDM2 (Homo sapiens) 6480464 deguelin results in increased expression of MDM2 mRNA CTD PMID:33512557 Mdm2 Mouse DENSPM multiple interactions ISO MDM2 (Homo sapiens) 6480464 Fluorouracil promotes the reaction [N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein]; TP53 protein promotes more ... CTD PMID:15546879 Mdm2 Mouse DENSPM increases expression ISO MDM2 (Homo sapiens) 6480464 N(1),N(11)-diethylnorspermine results in increased expression of MDM2 protein CTD PMID:15546879 Mdm2 Mouse deoxynivalenol increases expression ISO MDM2 (Homo sapiens) 6480464 deoxynivalenol results in increased expression of MDM2 mRNA CTD PMID:31863870 Mdm2 Mouse desferrioxamine B increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Deferoxamine results in increased expression of MDM2 protein CTD PMID:19950214 Mdm2 Mouse diallyl disulfide multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of MDM2 mRNA CTD PMID:31077537 Mdm2 Mouse diallyl trisulfide decreases expression ISO MDM2 (Homo sapiens) 6480464 diallyl trisulfide results in decreased expression of MDM2 protein CTD PMID:24415872 Mdm2 Mouse diallyl trisulfide increases degradation ISO MDM2 (Homo sapiens) 6480464 diallyl trisulfide results in increased degradation of MDM2 protein CTD PMID:23754639 Mdm2 Mouse diarsenic trioxide decreases expression ISO MDM2 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased expression of MDM2 mRNA CTD PMID:20458559 Mdm2 Mouse diarsenic trioxide increases expression ISO MDM2 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of MDM2 mRNA CTD PMID:20862710|PMID:25574600|PMID:26705709 Mdm2 Mouse diarsenic trioxide multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA] CTD PMID:17487067 Mdm2 Mouse diarsenic trioxide decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Arsenic Trioxide results in decreased expression of MDM2 mRNA CTD PMID:21145380 Mdm2 Mouse diarsenic trioxide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of MDM2 mRNA CTD PMID:17487067 Mdm2 Mouse diazinon affects expression ISO Mdm2 (Rattus norvegicus) 6480464 Diazinon affects the expression of MDM2 mRNA CTD PMID:22546817 Mdm2 Mouse dibenz[a,h]anthracene increases expression EXP 6480464 1,2,5,6-dibenzanthracene results in increased expression of MDM2 mRNA CTD PMID:26377693 Mdm2 Mouse diclofenac decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Diclofenac results in decreased expression of MDM2 mRNA CTD PMID:17202759 Mdm2 Mouse dieldrin affects expression ISO Mdm2 (Rattus norvegicus) 6480464 Dieldrin affects the expression of MDM2 mRNA CTD PMID:22546817 Mdm2 Mouse dieldrin affects methylation EXP 6480464 Dieldrin affects the methylation of MDM2 gene CTD PMID:38995845 Mdm2 Mouse diepoxybutane multiple interactions ISO MDM2 (Homo sapiens) 6480464 diepoxybutane inhibits the reaction [TP53 protein binds to MDM2 protein] CTD PMID:20024960 Mdm2 Mouse diethylstilbestrol affects mutagenesis EXP 6480464 Diethylstilbestrol affects the mutagenesis of MDM2 gene CTD PMID:7916985 Mdm2 Mouse diethylstilbestrol decreases expression EXP 6480464 Diethylstilbestrol results in decreased expression of MDM2 mRNA CTD PMID:21041162 Mdm2 Mouse diethylstilbestrol increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of MDM2 mRNA CTD PMID:15890375 Mdm2 Mouse diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of MDM2 mRNA CTD PMID:15545218 Mdm2 Mouse dimethylarsinic acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Cacodylic Acid results in increased expression of MDM2 mRNA CTD PMID:17481689 Mdm2 Mouse dimethylarsinic acid multiple interactions ISO MDM2 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MDM2 more ... CTD PMID:23192986 Mdm2 Mouse dioxygen multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Cisplatin co-treated with eprenetapopt co-treated with Oxygen deficiency] results in increased expression of MDM2 mRNA; more ... CTD PMID:19578757|PMID:29690507 Mdm2 Mouse dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MDM2 mRNA CTD PMID:30529165 Mdm2 Mouse dioxygen increases expression ISO MDM2 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of MDM2 mRNA; Oxygen deficiency results in increased expression more ... CTD PMID:19502547|PMID:19578757|PMID:19714248|PMID:25596134 Mdm2 Mouse disodium selenite increases expression ISO MDM2 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of MDM2 mRNA CTD PMID:24383545 Mdm2 Mouse dorsomorphin multiple interactions ISO MDM2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdm2 Mouse doxorubicin multiple interactions ISO MDM2 (Homo sapiens) 6480464 Doxorubicin inhibits the reaction [TP53 protein binds to MDM2 protein]; Doxorubicin results in increased activity more ... CTD PMID:17935137|PMID:17959036|PMID:19351845|PMID:19714248|PMID:21624110|PMID:26317544 Mdm2 Mouse doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of MDM2 mRNA CTD PMID:29653124 Mdm2 Mouse doxorubicin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of MDM2 mRNA CTD PMID:12187937|PMID:27255381|PMID:34713381 Mdm2 Mouse doxorubicin decreases response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 protein results in decreased susceptibility to Doxorubicin CTD PMID:26317544 Mdm2 Mouse doxorubicin increases expression ISO MDM2 (Homo sapiens) 6480464 Doxorubicin results in increased expression of MDM2 mRNA; Doxorubicin results in increased expression of MDM2 more ... CTD PMID:14665630|PMID:17653088|PMID:17959036|PMID:19074854|PMID:19560264|PMID:26317544 Mdm2 Mouse doxorubicin affects expression ISO MDM2 (Homo sapiens) 6480464 Doxorubicin affects the expression of MDM2 mRNA CTD PMID:25529476|PMID:29803840 Mdm2 Mouse doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of MDM2 mRNA CTD PMID:14766674|PMID:16949053|PMID:34713381 Mdm2 Mouse doxorubicin multiple interactions EXP 6480464 pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA] CTD PMID:14766674 Mdm2 Mouse doxorubicin increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Doxorubicin results in increased phosphorylation of MDM2 protein CTD PMID:17935137 Mdm2 Mouse eflornithine decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Eflornithine results in decreased expression of MDM2 mRNA CTD PMID:11502571 Mdm2 Mouse ellipticine decreases response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 promoter SNP results in decreased susceptibility to ellipticine CTD PMID:17575151 Mdm2 Mouse endosulfan increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of MDM2 mRNA CTD PMID:29391264 Mdm2 Mouse epoxiconazole multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of MDM2 mRNA; [cyproconazole more ... CTD PMID:29038839 Mdm2 Mouse epoxiconazole increases expression ISO Mdm2 (Rattus norvegicus) 6480464 epoxiconazole results in increased expression of MDM2 mRNA CTD PMID:29038839 Mdm2 Mouse escitalopram increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Escitalopram results in increased expression of MDM2 mRNA CTD PMID:28467792 Mdm2 Mouse ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of MDM2 mRNA CTD PMID:22535522 Mdm2 Mouse ethyl methanesulfonate increases expression ISO MDM2 (Homo sapiens) 6480464 Ethyl Methanesulfonate results in increased expression of MDM2 mRNA CTD PMID:23649840 Mdm2 Mouse etoposide increases expression ISO MDM2 (Homo sapiens) 6480464 Etoposide results in increased expression of MDM2 mRNA; Etoposide results in increased expression of MDM2 more ... CTD PMID:16120219|PMID:18096571|PMID:25078064|PMID:30177839|PMID:31542801 Mdm2 Mouse etoposide decreases expression ISO MDM2 (Homo sapiens) 6480464 Etoposide results in decreased expression of MDM2 protein CTD PMID:26259609 Mdm2 Mouse etoposide increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Etoposide results in increased phosphorylation of MDM2 protein CTD PMID:17935137|PMID:25744307 Mdm2 Mouse etoposide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Etoposide results in increased expression of MDM2 protein CTD PMID:15459018 Mdm2 Mouse etoposide multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein] CTD PMID:15459018 Mdm2 Mouse etoposide decreases response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 promoter SNP results in decreased susceptibility to Etoposide CTD PMID:17575151 Mdm2 Mouse etoposide multiple interactions ISO MDM2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]]; more ... CTD PMID:17575151|PMID:17935137|PMID:25744307|PMID:30177839 Mdm2 Mouse EUK-134 multiple interactions ISO MDM2 (Homo sapiens) 6480464 EUK-134 inhibits the reaction [Hydrogen Peroxide results in decreased expression of MDM2 protein]; EUK-134 inhibits more ... CTD PMID:25005833 Mdm2 Mouse fenbendazole increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Fenbendazole results in increased expression of MDM2 mRNA CTD PMID:23411599 Mdm2 Mouse fenofibrate decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Fenofibrate results in decreased expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse fipronil increases expression ISO Mdm2 (Rattus norvegicus) 6480464 fipronil results in increased expression of MDM2 mRNA CTD PMID:23962444 Mdm2 Mouse flavanones increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Flavanones results in increased phosphorylation of MDM2 protein CTD PMID:21616090 Mdm2 Mouse flucytosine increases expression ISO MDM2 (Homo sapiens) 6480464 Flucytosine results in increased expression of MDM2 protein CTD PMID:15592511 Mdm2 Mouse fluoranthene multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of MDM2 mRNA CTD PMID:17690111 Mdm2 Mouse flutamide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Flutamide results in increased expression of MDM2 mRNA CTD PMID:24136188 Mdm2 Mouse folic acid affects expression ISO MDM2 (Homo sapiens) 6480464 Folic Acid affects the expression of MDM2 mRNA CTD PMID:16361273 Mdm2 Mouse folic acid multiple interactions EXP 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of MDM2 mRNA; [Methionine deficiency co-treated more ... CTD PMID:20938992|PMID:22206623 Mdm2 Mouse formaldehyde increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Formaldehyde results in increased expression of MDM2 mRNA; Formaldehyde results in increased expression of MDM2 more ... CTD PMID:18045764 Mdm2 Mouse formaldehyde increases expression ISO MDM2 (Homo sapiens) 6480464 Formaldehyde results in increased expression of MDM2 mRNA; Formaldehyde results in increased expression of MDM2 more ... CTD PMID:18045764|PMID:23649840 Mdm2 Mouse formononetin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 formononetin results in increased expression of MDM2 protein CTD PMID:28414026 Mdm2 Mouse FR900359 decreases phosphorylation ISO MDM2 (Homo sapiens) 6480464 FR900359 results in decreased phosphorylation of MDM2 protein CTD PMID:37730182 Mdm2 Mouse fumonisin B1 multiple interactions ISO MDM2 (Homo sapiens) 6480464 fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; fumonisin more ... CTD PMID:18206046 Mdm2 Mouse furan increases expression ISO Mdm2 (Rattus norvegicus) 6480464 furan results in increased expression of MDM2 mRNA CTD PMID:22079235 Mdm2 Mouse furosemide affects expression ISO Mdm2 (Rattus norvegicus) 6480464 Furosemide affects the expression of MDM2 mRNA CTD PMID:17497460 Mdm2 Mouse ganciclovir increases expression ISO MDM2 (Homo sapiens) 6480464 Ganciclovir results in increased expression of MDM2 protein CTD PMID:15592511 Mdm2 Mouse geldanamycin increases expression ISO MDM2 (Homo sapiens) 6480464 geldanamycin results in increased expression of MDM2 mRNA CTD PMID:26705709 Mdm2 Mouse gemcitabine decreases expression ISO MDM2 (Homo sapiens) 6480464 Gemcitabine results in decreased expression of MDM2 mRNA CTD PMID:20103597 Mdm2 Mouse gemcitabine increases expression ISO MDM2 (Homo sapiens) 6480464 Gemcitabine results in increased expression of MDM2 mRNA CTD PMID:17039268 Mdm2 Mouse genistein decreases expression EXP 6480464 Genistein results in decreased expression of MDM2 mRNA CTD PMID:21048042 Mdm2 Mouse gentamycin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of MDM2 mRNA CTD PMID:22061828|PMID:33387578 Mdm2 Mouse glyphosate decreases expression ISO MDM2 (Homo sapiens) 6480464 Glyphosate results in decreased expression of MDM2 mRNA CTD PMID:31295307 Mdm2 Mouse gold atom decreases expression ISO MDM2 (Homo sapiens) 6480464 Gold analog results in decreased expression of MDM2 mRNA CTD PMID:36057382 Mdm2 Mouse gold(0) decreases expression ISO MDM2 (Homo sapiens) 6480464 Gold analog results in decreased expression of MDM2 mRNA CTD PMID:36057382 Mdm2 Mouse GSK-J4 increases expression ISO MDM2 (Homo sapiens) 6480464 GSK-J4 results in increased expression of MDM2 mRNA CTD PMID:29301935 Mdm2 Mouse GW 501516 multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 MDM2 protein inhibits the reaction [GW 501516 results in increased activity of PPARB protein] CTD PMID:19103650 Mdm2 Mouse hydrogen peroxide multiple interactions ISO MDM2 (Homo sapiens) 6480464 EUK-134 inhibits the reaction [Hydrogen Peroxide results in decreased expression of MDM2 protein]; Hydrogen Peroxide more ... CTD PMID:21552291|PMID:25005833 Mdm2 Mouse hydrogen peroxide increases expression ISO MDM2 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of MDM2 mRNA CTD PMID:21751221 Mdm2 Mouse hydrogen peroxide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of MDM2 mRNA CTD PMID:14689451|PMID:27525270 Mdm2 Mouse hydrogen peroxide multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Quercetin co-treated with Hydrogen Peroxide] results in increased expression of MDM2 mRNA; Hydrogen Peroxide results more ... CTD PMID:14689451|PMID:27525270 Mdm2 Mouse hydrogen peroxide decreases expression ISO MDM2 (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of MDM2 protein CTD PMID:25005833 Mdm2 Mouse hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide promotes the reaction [TRP53 protein results in increased expression of MDM2] CTD PMID:21552291 Mdm2 Mouse hydroquinone increases expression ISO MDM2 (Homo sapiens) 6480464 hydroquinone results in increased expression of MDM2 mRNA CTD PMID:29221148 Mdm2 Mouse hydroxyurea increases expression ISO MDM2 (Homo sapiens) 6480464 Hydroxyurea results in increased expression of MDM2 mRNA CTD PMID:18647660 Mdm2 Mouse hydroxyurea increases expression EXP 6480464 Hydroxyurea results in increased expression of MDM2 mRNA CTD PMID:16356682 Mdm2 Mouse hydroxyurea affects expression EXP 6480464 Hydroxyurea affects the expression of MDM2 protein CTD PMID:16356682 Mdm2 Mouse Icaritin decreases expression ISO MDM2 (Homo sapiens) 6480464 icaritin results in decreased expression of MDM2 protein CTD PMID:38431053 Mdm2 Mouse ifosfamide increases expression ISO MDM2 (Homo sapiens) 6480464 Ifosfamide results in increased expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse Indeno[1,2,3-cd]pyrene increases expression ISO MDM2 (Homo sapiens) 6480464 indeno(1,2,3-cd)pyrene results in increased expression of MDM2 mRNA CTD PMID:32251684 Mdm2 Mouse irinotecan increases expression ISO MDM2 (Homo sapiens) 6480464 Irinotecan metabolite results in increased expression of MDM2 mRNA; Irinotecan results in increased expression of more ... CTD PMID:15956246 Mdm2 Mouse isoflurane decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Isoflurane results in decreased expression of MDM2 mRNA CTD PMID:16978161 Mdm2 Mouse kojic acid multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA CTD PMID:18544905 Mdm2 Mouse L-ascorbic acid multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] CTD PMID:21262251 Mdm2 Mouse L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... CTD PMID:20938992 Mdm2 Mouse leflunomide increases expression ISO MDM2 (Homo sapiens) 6480464 leflunomide results in increased expression of MDM2 mRNA CTD PMID:28988120 Mdm2 Mouse leptomycin B increases expression ISO MDM2 (Homo sapiens) 6480464 leptomycin B results in increased expression of MDM2 mRNA CTD PMID:20803015 Mdm2 Mouse Leucomalachite green increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 leucomalachite green results in increased phosphorylation of MDM2 protein CTD PMID:26558467 Mdm2 Mouse linalool increases expression ISO MDM2 (Homo sapiens) 6480464 linalool results in increased expression of MDM2 mRNA CTD PMID:19922762 Mdm2 Mouse lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of MDM2 mRNA CTD PMID:10975854|PMID:23107598 Mdm2 Mouse lipopolysaccharide increases expression ISO MDM2 (Homo sapiens) 6480464 Lipopolysaccharides results in increased expression of MDM2 mRNA CTD PMID:35953652 Mdm2 Mouse lipopolysaccharide multiple interactions EXP 6480464 Indirubin E804 inhibits the reaction [Lipopolysaccharides results in increased expression of MDM2 mRNA] CTD PMID:23107598 Mdm2 Mouse lupeol multiple interactions ISO MDM2 (Homo sapiens) 6480464 lupeol inhibits the reaction [mancozeb results in increased expression of MDM2 mRNA] CTD PMID:27235710 Mdm2 Mouse luteolin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Luteolin results in increased expression of MDM2 mRNA CTD PMID:31201582 Mdm2 Mouse luteolin multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Luteolin promotes the reaction [Hydrogen Peroxide results in increased expression of MDM2 mRNA] CTD PMID:27525270 Mdm2 Mouse LY294002 increases expression ISO MDM2 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of MDM2 protein CTD PMID:16412023 Mdm2 Mouse mancozeb multiple interactions ISO MDM2 (Homo sapiens) 6480464 lupeol inhibits the reaction [mancozeb results in increased expression of MDM2 mRNA] CTD PMID:27235710 Mdm2 Mouse mancozeb increases expression ISO MDM2 (Homo sapiens) 6480464 mancozeb results in increased expression of MDM2 mRNA CTD PMID:27235710 Mdm2 Mouse manganese atom multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein; PPM1D protein inhibits more ... CTD PMID:25791630 Mdm2 Mouse manganese atom decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Manganese results in decreased expression of MDM2 protein CTD PMID:25791630 Mdm2 Mouse manganese(0) multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein; PPM1D protein inhibits more ... CTD PMID:25791630 Mdm2 Mouse manganese(0) decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Manganese results in decreased expression of MDM2 protein CTD PMID:25791630 Mdm2 Mouse manganese(II) chloride increases expression ISO Mdm2 (Rattus norvegicus) 6480464 manganese chloride results in increased expression of MDM2 mRNA CTD PMID:28801915 Mdm2 Mouse menadione decreases expression ISO MDM2 (Homo sapiens) 6480464 Vitamin K 3 results in decreased expression of MDM2 protein CTD PMID:25005833 Mdm2 Mouse menadione multiple interactions ISO MDM2 (Homo sapiens) 6480464 EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of MDM2 protein] CTD PMID:25005833 Mdm2 Mouse mercury dibromide increases expression ISO MDM2 (Homo sapiens) 6480464 mercuric bromide results in increased expression of MDM2 mRNA CTD PMID:26272509 Mdm2 Mouse mercury dibromide multiple interactions ISO MDM2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdm2 Mouse mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of MDM2 mRNA CTD PMID:23202902 Mdm2 Mouse metformin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Metformin results in increased expression of MDM2 mRNA CTD PMID:25596134 Mdm2 Mouse methapyrilene decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Methapyrilene results in decreased expression of MDM2 mRNA CTD PMID:22584684 Mdm2 Mouse methapyrilene increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of MDM2 mRNA CTD PMID:15890375|PMID:18619722|PMID:25242409|PMID:26558467|PMID:30467583 Mdm2 Mouse methapyrilene increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 Methapyrilene results in increased phosphorylation of MDM2 protein CTD PMID:26558467 Mdm2 Mouse methotrexate multiple interactions ISO MDM2 (Homo sapiens) 6480464 Methotrexate results in increased activity of and results in increased expression of MDM2 protein; nutlin more ... CTD PMID:21624110 Mdm2 Mouse methotrexate affects expression EXP 6480464 Methotrexate affects the expression of MDM2 mRNA CTD PMID:18502557 Mdm2 Mouse methotrexate increases expression ISO MDM2 (Homo sapiens) 6480464 Methotrexate results in increased expression of MDM2 mRNA; Methotrexate results in increased expression of MDM2 more ... CTD PMID:17637740|PMID:21678067|PMID:24449571 Mdm2 Mouse methyl caffeate affects binding ISO MDM2 (Homo sapiens) 6480464 methyl caffeate binds to MDM2 protein CTD PMID:26415618 Mdm2 Mouse methyl methanesulfonate increases expression ISO MDM2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of MDM2 mRNA; Methyl Methanesulfonate results in increased expression more ... CTD PMID:23649840|PMID:25078064 Mdm2 Mouse methylarsonic acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 monomethylarsonic acid results in increased expression of MDM2 mRNA CTD PMID:17481689 Mdm2 Mouse methylarsonic acid multiple interactions ISO MDM2 (Homo sapiens) 6480464 [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MDM2 more ... CTD PMID:23192986 Mdm2 Mouse methylmercury chloride decreases expression EXP 6480464 methylmercuric chloride results in decreased expression of MDM2 mRNA CTD PMID:23202902 Mdm2 Mouse methylmercury chloride increases expression ISO MDM2 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of MDM2 mRNA CTD PMID:28001369 Mdm2 Mouse methylmercury(1+) multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA CTD PMID:17905399 Mdm2 Mouse microcystin-LR decreases expression EXP 6480464 cyanoginosin LR results in decreased expression of MDM2 mRNA; cyanoginosin LR results in decreased expression more ... CTD PMID:28414124 Mdm2 Mouse microcystin-LR decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 cyanoginosin LR results in decreased expression of MDM2 protein CTD PMID:31157505 Mdm2 Mouse mifepristone increases expression EXP 6480464 Mifepristone results in increased expression of MDM2 mRNA CTD PMID:12605714 Mdm2 Mouse mitomycin C multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Mitomycin results in increased stability of TP53 protein] which results in increased expression of MDM2 more ... CTD PMID:20536192 Mdm2 Mouse mitomycin C increases expression ISO MDM2 (Homo sapiens) 6480464 Mitomycin results in increased expression of MDM2 protein CTD PMID:18096571 Mdm2 Mouse mitomycin C increases expression EXP 6480464 Mitomycin results in increased expression of MDM2 mRNA CTD PMID:25270620 Mdm2 Mouse mitoxantrone decreases response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 promoter SNP results in decreased susceptibility to Mitoxantrone CTD PMID:17575151 Mdm2 Mouse mono(2-ethylhexyl) phthalate decreases expression ISO MDM2 (Homo sapiens) 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of MDM2 protein CTD PMID:24706461 Mdm2 Mouse mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of MDM2 mRNA CTD PMID:33162236 Mdm2 Mouse monocrotaline multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of more ... CTD PMID:21224054 Mdm2 Mouse monosodium L-glutamate multiple interactions EXP 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MDM2 mRNA CTD PMID:23783067 Mdm2 Mouse motexafin gadolinium multiple interactions ISO MDM2 (Homo sapiens) 6480464 motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] CTD PMID:16357179 Mdm2 Mouse motexafin gadolinium increases expression ISO MDM2 (Homo sapiens) 6480464 motexafin gadolinium results in increased expression of MDM2 mRNA CTD PMID:16357179 Mdm2 Mouse N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine increases expression ISO MDM2 (Homo sapiens) 6480464 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of MDM2 mRNA CTD PMID:33645215 Mdm2 Mouse N-acetylsphingosine decreases expression ISO MDM2 (Homo sapiens) 6480464 N-acetylsphingosine results in decreased expression of MDM2 mRNA; N-acetylsphingosine results in decreased expression of MDM2 more ... CTD PMID:18206046 Mdm2 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MDM2 mRNA CTD PMID:20061341 Mdm2 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO MDM2 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] CTD PMID:17575151 Mdm2 Mouse N-ethyl-N-nitrosourea increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Ethylnitrosourea results in increased expression of MDM2 mRNA CTD PMID:15954086 Mdm2 Mouse N-ethyl-N-nitrosourea increases expression EXP 6480464 Ethylnitrosourea results in increased expression of MDM2 mRNA CTD PMID:19100860 Mdm2 Mouse N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO MDM2 (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA CTD PMID:12634122 Mdm2 Mouse N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions EXP 6480464 Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] CTD PMID:12135628 Mdm2 Mouse N-methyl-N'-nitro-N-nitrosoguanidine increases expression EXP 6480464 Methylnitronitrosoguanidine results in increased expression of MDM2 protein CTD PMID:12135628 Mdm2 Mouse N-methyl-N-nitrosourea increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Methylnitrosourea results in increased expression of MDM2 mRNA CTD PMID:28688903 Mdm2 Mouse N-nitrosodiethylamine multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein; more ... CTD PMID:11003613|PMID:18544905 Mdm2 Mouse N-nitrosodiethylamine increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of MDM2 mRNA; Diethylnitrosamine results in increased expression of MDM2 more ... CTD PMID:14555611|PMID:15459018|PMID:25242409 Mdm2 Mouse N-nitrosodiethylamine multiple interactions EXP 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MDM2 mRNA] CTD PMID:17854601 Mdm2 Mouse N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of MDM2 mRNA; Diethylnitrosamine results in increased expression of MDM2 more ... CTD PMID:17854601|PMID:18506893|PMID:19100860|PMID:21607683 Mdm2 Mouse N-nitrosodimethylamine increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased expression of MDM2 mRNA CTD PMID:14600272|PMID:15890375 Mdm2 Mouse N-nitrosomorpholine increases expression ISO Mdm2 (Rattus norvegicus) 6480464 N-nitrosomorpholine results in increased expression of MDM2 mRNA; N-nitrosomorpholine results in increased expression of MDM2 more ... CTD PMID:14587038|PMID:19716841 Mdm2 Mouse N-Vinyl-2-pyrrolidone multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [N-vinyl-2-pyrrolidinone binds to N-vinyl-2-pyrrolidinone] which affects the expression of MDM2 mRNA CTD PMID:22037397 Mdm2 Mouse nefazodone increases expression ISO Mdm2 (Rattus norvegicus) 6480464 nefazodone results in increased expression of MDM2 mRNA CTD PMID:24136188 Mdm2 Mouse nickel atom increases expression ISO MDM2 (Homo sapiens) 6480464 Nickel results in increased expression of MDM2 mRNA CTD PMID:24068677 Mdm2 Mouse nickel atom multiple interactions ISO MDM2 (Homo sapiens) 6480464 TP53 protein affects the reaction [Nickel results in increased expression of MDM2 mRNA] CTD PMID:24068677 Mdm2 Mouse nickel dichloride increases expression ISO MDM2 (Homo sapiens) 6480464 nickel chloride results in increased expression of MDM2 mRNA CTD PMID:23566959|PMID:28552779 Mdm2 Mouse nickel dichloride affects expression ISO Mdm2 (Rattus norvegicus) 6480464 nickel chloride affects the expression of MDM2 mRNA CTD PMID:22546817 Mdm2 Mouse nickel dichloride multiple interactions ISO MDM2 (Homo sapiens) 6480464 TP53 protein affects the reaction [nickel chloride results in increased expression of MDM2 mRNA] CTD PMID:23566959 Mdm2 Mouse nicotinamide increases expression ISO MDM2 (Homo sapiens) 6480464 Niacinamide results in increased expression of MDM2 mRNA CTD PMID:16998810 Mdm2 Mouse nicotine multiple interactions ISO MDM2 (Homo sapiens) 6480464 [[Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 more ... CTD PMID:30272249 Mdm2 Mouse nimesulide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 nimesulide results in increased expression of MDM2 mRNA CTD PMID:24136188 Mdm2 Mouse nitenpyram increases expression ISO MDM2 (Homo sapiens) 6480464 nitenpyram results in increased expression of MDM2 mRNA CTD PMID:35568224 Mdm2 Mouse Nodularin increases expression ISO MDM2 (Homo sapiens) 6480464 nodularin results in increased expression of MDM2 mRNA CTD PMID:30562542 Mdm2 Mouse Nutlin-3 multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Dactinomycin co-treated with nutlin 3] results in increased expression of MDM2 mRNA; [Dactinomycin co-treated with more ... CTD PMID:16439685|PMID:20422343|PMID:21109480|PMID:21509038|PMID:21624110|PMID:22044530|PMID:22260869|PMID:35213076|PMID:38460933 Mdm2 Mouse Nutlin-3 decreases expression ISO MDM2 (Homo sapiens) 6480464 nutlin 3 results in decreased expression of MDM2 protein CTD PMID:35213076 Mdm2 Mouse Nutlin-3 multiple interactions EXP 6480464 nutlin 3 inhibits the reaction [Cisplatin results in increased expression of MDM2 protein] CTD PMID:32856486 Mdm2 Mouse Nutlin-3 increases expression EXP 6480464 nutlin 3 results in increased expression of MDM2 mRNA CTD PMID:16949053 Mdm2 Mouse Nutlin-3 increases expression ISO MDM2 (Homo sapiens) 6480464 nutlin 3 results in increased expression of MDM2 mRNA; nutlin 3 results in increased expression more ... CTD PMID:16014563|PMID:16439685|PMID:19098008|PMID:21109480|PMID:22044530|PMID:38460933 Mdm2 Mouse O-methyleugenol increases expression ISO Mdm2 (Rattus norvegicus) 6480464 methyleugenol results in increased expression of MDM2 mRNA CTD PMID:26011634 Mdm2 Mouse ochratoxin A increases expression ISO Mdm2 (Rattus norvegicus) 6480464 ochratoxin A results in increased expression of MDM2 mRNA CTD PMID:23358140 Mdm2 Mouse ochratoxin A decreases expression ISO MDM2 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of MDM2 mRNA CTD PMID:30763683 Mdm2 Mouse Octicizer increases expression ISO MDM2 (Homo sapiens) 6480464 2-ethylhexyldiphenylphosphate results in increased expression of MDM2 mRNA CTD PMID:30981936 Mdm2 Mouse okadaic acid decreases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Okadaic Acid results in decreased phosphorylation of MDM2 protein CTD PMID:38832940 Mdm2 Mouse ortho-Aminoazotoluene increases expression EXP 6480464 o-Aminoazotoluene results in increased expression of MDM2 mRNA CTD PMID:15346788 Mdm2 Mouse ouabain multiple interactions ISO MDM2 (Homo sapiens) 6480464 Ouabain results in decreased expression of and results in decreased phosphorylation of MDM2 protein CTD PMID:31436044 Mdm2 Mouse oxaliplatin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 oxaliplatin results in increased expression of MDM2 mRNA CTD PMID:25729387 Mdm2 Mouse oxaliplatin multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of MDM2 mRNA CTD PMID:25729387 Mdm2 Mouse oxfendazole increases expression ISO Mdm2 (Rattus norvegicus) 6480464 oxfendazole results in increased expression of MDM2 mRNA CTD PMID:26558467 Mdm2 Mouse oxfendazole decreases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 oxfendazole results in decreased phosphorylation of MDM2 protein CTD PMID:26558467 Mdm2 Mouse p-chloromercuribenzoic acid increases expression ISO MDM2 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of MDM2 mRNA CTD PMID:26272509 Mdm2 Mouse p-chloromercuribenzoic acid multiple interactions ISO MDM2 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdm2 Mouse paclitaxel decreases response to substance ISO MDM2 (Homo sapiens) 6480464 MDM2 protein results in decreased susceptibility to Paclitaxel CTD PMID:13130078 Mdm2 Mouse palmatine affects binding ISO MDM2 (Homo sapiens) 6480464 palmatine binds to MDM2 protein CTD PMID:35997646 Mdm2 Mouse paracetamol multiple interactions EXP 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA; PPARA affects the reaction [[Clofibrate more ... CTD PMID:17585979 Mdm2 Mouse paracetamol increases expression ISO MDM2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of MDM2 mRNA CTD PMID:22230336 Mdm2 Mouse paracetamol decreases expression ISO MDM2 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of MDM2 mRNA CTD PMID:21420995 Mdm2 Mouse paracetamol decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of MDM2 mRNA CTD PMID:21807079 Mdm2 Mouse paracetamol increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 Acetaminophen results in increased phosphorylation of MDM2 protein CTD PMID:16330492 Mdm2 Mouse paracetamol increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of MDM2 mRNA CTD PMID:17202762|PMID:33387578 Mdm2 Mouse paracetamol multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Acetaminophen promotes the reaction [MDM2 protein binds to TP53 protein] CTD PMID:16330492 Mdm2 Mouse paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of MDM2 mRNA CTD PMID:17562736 Mdm2 Mouse paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of MDM2 mRNA CTD PMID:26056430 Mdm2 Mouse Paraoxon-methyl increases expression ISO MDM2 (Homo sapiens) 6480464 methylparaoxon results in increased expression of MDM2 mRNA CTD PMID:18418871 Mdm2 Mouse paraquat multiple interactions EXP 6480464 GPX1 protein affects the reaction [Paraquat affects the expression of MDM2 mRNA] CTD PMID:12654481 Mdm2 Mouse paraquat increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Paraquat results in increased expression of MDM2 mRNA CTD PMID:32680482 Mdm2 Mouse paraquat increases expression ISO MDM2 (Homo sapiens) 6480464 Paraquat results in increased expression of MDM2 mRNA CTD PMID:20883675|PMID:34097952 Mdm2 Mouse parathion multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Estradiol co-treated with Parathion] results in increased expression of MDM2 mRNA CTD PMID:17622325 Mdm2 Mouse parathion-methyl increases expression ISO MDM2 (Homo sapiens) 6480464 Methyl Parathion results in increased expression of MDM2 mRNA CTD PMID:18418871 Mdm2 Mouse PCB138 increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 2,2',3',4,4',5-hexachlorobiphenyl results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse PD123319 multiple interactions ISO MDM2 (Homo sapiens) 6480464 PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA]; PD more ... CTD PMID:18206046 Mdm2 Mouse pentachlorophenol increases expression EXP 6480464 Pentachlorophenol results in increased expression of MDM2 mRNA CTD PMID:23892564 Mdm2 Mouse perfluorooctanoic acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of MDM2 mRNA CTD PMID:19162173 Mdm2 Mouse phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of MDM2 mRNA CTD PMID:19482888|PMID:20816995|PMID:25145657 Mdm2 Mouse phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MDM2 mRNA]; NR1I3 protein more ... CTD PMID:19482888 Mdm2 Mouse phenobarbital increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Phenobarbital results in increased phosphorylation of MDM2 protein CTD PMID:19751709 Mdm2 Mouse phenobarbital increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Phenobarbital results in increased expression of MDM2 mRNA CTD PMID:25145657 Mdm2 Mouse phenylmercury acetate increases expression ISO MDM2 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of MDM2 mRNA CTD PMID:26272509 Mdm2 Mouse phenylmercury acetate multiple interactions ISO MDM2 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdm2 Mouse phenytoin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of more ... CTD PMID:21224054 Mdm2 Mouse PhIP increases expression ISO MDM2 (Homo sapiens) 6480464 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of MDM2 protein CTD PMID:15635149 Mdm2 Mouse phlorizin decreases expression EXP 6480464 Phlorhizin results in decreased expression of MDM2 mRNA CTD PMID:22538082 Mdm2 Mouse phosphoramide mustard increases expression ISO Mdm2 (Rattus norvegicus) 6480464 phosphoramide mustard results in increased expression of MDM2 mRNA CTD PMID:26708502 Mdm2 Mouse picoxystrobin increases expression ISO MDM2 (Homo sapiens) 6480464 picoxystrobin results in increased expression of MDM2 mRNA CTD PMID:33512557 Mdm2 Mouse pifithrin-alpha hydrobromide multiple interactions EXP 6480464 pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA]; pifithrin inhibits the more ... CTD PMID:14766674|PMID:18940243 Mdm2 Mouse pifithrin-alpha hydrobromide multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA] CTD PMID:17487067 Mdm2 Mouse piperonyl butoxide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Piperonyl Butoxide results in increased expression of MDM2 mRNA CTD PMID:15890375|PMID:22484513 Mdm2 Mouse pirinixic acid multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 MDM2 protein affects the reaction [pirinixic acid results in increased activity of PPARA protein]; MDM2 more ... CTD PMID:19103650 Mdm2 Mouse pirinixic acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of MDM2 mRNA CTD PMID:15890375|PMID:19162173 Mdm2 Mouse platycodin D decreases expression ISO MDM2 (Homo sapiens) 6480464 platycodin D results in decreased expression of MDM2 protein CTD PMID:25431082|PMID:27432230 Mdm2 Mouse platycodin D multiple interactions ISO MDM2 (Homo sapiens) 6480464 MDM2 protein inhibits the reaction [platycodin D results in increased expression of FOXO3 protein] CTD PMID:25431082 Mdm2 Mouse poly(vinylpyrrolidone) multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results more ... CTD PMID:27387714 Mdm2 Mouse potassium bromate increases expression ISO MDM2 (Homo sapiens) 6480464 potassium bromate results in increased expression of MDM2 mRNA CTD PMID:30559759 Mdm2 Mouse potassium dichromate multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] CTD PMID:21262251 Mdm2 Mouse potassium dichromate decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 Potassium Dichromate results in decreased expression of MDM2 protein CTD PMID:21262251 Mdm2 Mouse pravastatin increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Pravastatin results in increased phosphorylation of MDM2 protein CTD PMID:15625077 Mdm2 Mouse pravastatin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Pravastatin results in increased expression of MDM2 protein CTD PMID:15625077 Mdm2 Mouse pravastatin multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 more ... CTD PMID:15625077 Mdm2 Mouse pregnenolone 16alpha-carbonitrile increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of MDM2 mRNA CTD PMID:19162173 Mdm2 Mouse prochloraz multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of MDM2 mRNA CTD PMID:29038839 Mdm2 Mouse procymidone decreases expression ISO Mdm2 (Rattus norvegicus) 6480464 procymidone results in decreased expression of MDM2 mRNA CTD PMID:15686871 Mdm2 Mouse promethazine increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 Promethazine results in increased phosphorylation of MDM2 protein CTD PMID:26558467 Mdm2 Mouse propanal increases expression ISO MDM2 (Homo sapiens) 6480464 propionaldehyde results in increased expression of MDM2 mRNA CTD PMID:26079696 Mdm2 Mouse PX-866 decreases phosphorylation ISO MDM2 (Homo sapiens) 6480464 PX-866 results in decreased phosphorylation of MDM2 protein CTD PMID:27017931 Mdm2 Mouse PX-866 multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein CTD PMID:27017931 Mdm2 Mouse quercetin multiple interactions ISO MDM2 (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of and results in decreased expression of MDM2 protein CTD PMID:17973296 Mdm2 Mouse quercetin increases expression ISO MDM2 (Homo sapiens) 6480464 Quercetin results in increased expression of MDM2 mRNA CTD PMID:21632981|PMID:23727915|PMID:24849437 Mdm2 Mouse quercetin multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Quercetin co-treated with Hydrogen Peroxide] results in increased expression of MDM2 mRNA CTD PMID:27525270 Mdm2 Mouse quercetin decreases expression ISO MDM2 (Homo sapiens) 6480464 Quercetin results in decreased expression of MDM2 protein CTD PMID:21933852 Mdm2 Mouse quercetin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Quercetin results in increased expression of MDM2 mRNA CTD PMID:31201582 Mdm2 Mouse raloxifene multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein CTD PMID:27017931 Mdm2 Mouse reactive oxygen species multiple interactions ISO MDM2 (Homo sapiens) 6480464 [[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which more ... CTD PMID:27634759 Mdm2 Mouse resveratrol multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Plant Extracts co-treated with Resveratrol] results in increased expression of MDM2 mRNA; Capsaicin promotes the more ... CTD PMID:15542774|PMID:19846903|PMID:23557933 Mdm2 Mouse resveratrol increases expression ISO MDM2 (Homo sapiens) 6480464 resveratrol results in increased expression of MDM2 mRNA CTD PMID:15280659|PMID:15767336|PMID:25888808 Mdm2 Mouse resveratrol multiple interactions EXP 6480464 [resveratrol results in increased phosphorylation of TRP53 protein] inhibits the reaction [TRP53 protein binds to more ... CTD PMID:11245472 Mdm2 Mouse resveratrol decreases expression ISO MDM2 (Homo sapiens) 6480464 resveratrol results in decreased expression of MDM2 mRNA; resveratrol results in decreased expression of MDM2 more ... CTD PMID:16998810|PMID:19846903|PMID:20878097|PMID:25667456 Mdm2 Mouse resveratrol increases expression EXP 6480464 resveratrol results in increased expression of MDM2 mRNA; resveratrol results in increased expression of MDM2 more ... CTD PMID:11245472|PMID:16081268|PMID:16369916 Mdm2 Mouse resveratrol affects expression EXP 6480464 resveratrol affects the expression of MDM2 protein CTD PMID:16369916 Mdm2 Mouse rifampicin multiple interactions EXP 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of more ... CTD PMID:21224054 Mdm2 Mouse rotenone increases expression ISO MDM2 (Homo sapiens) 6480464 Rotenone results in increased expression of MDM2 mRNA CTD PMID:33512557 Mdm2 Mouse ruthenium atom decreases expression ISO MDM2 (Homo sapiens) 6480464 Ruthenium results in decreased expression of MDM2 protein CTD PMID:17210701 Mdm2 Mouse S-(1,2-dichlorovinyl)-L-cysteine increases expression ISO MDM2 (Homo sapiens) 6480464 S-(1,2-dichlorovinyl)cysteine results in increased expression of MDM2 mRNA CTD PMID:36576512 Mdm2 Mouse SB 431542 multiple interactions ISO MDM2 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... CTD PMID:27188386 Mdm2 Mouse selinexor increases expression ISO MDM2 (Homo sapiens) 6480464 selinexor results in increased expression of MDM2 protein CTD PMID:37899423 Mdm2 Mouse selinexor multiple interactions ISO MDM2 (Homo sapiens) 6480464 [INCB057643 co-treated with selinexor] results in increased expression of MDM2 protein CTD PMID:37899423 Mdm2 Mouse silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of MDM2 mRNA CTD PMID:19073995 Mdm2 Mouse silver atom multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results more ... CTD PMID:27387714 Mdm2 Mouse silver atom decreases expression ISO MDM2 (Homo sapiens) 6480464 Silver results in decreased expression of MDM2 mRNA CTD PMID:26014281 Mdm2 Mouse silver(0) multiple interactions ISO MDM2 (Homo sapiens) 6480464 [Silver co-treated with Povidone] affects the expression of MDM2 protein; [Silver co-treated with Povidone] results more ... CTD PMID:27387714 Mdm2 Mouse silver(0) decreases expression ISO MDM2 (Homo sapiens) 6480464 Silver results in decreased expression of MDM2 mRNA CTD PMID:26014281 Mdm2 Mouse simvastatin increases phosphorylation ISO MDM2 (Homo sapiens) 6480464 Simvastatin results in increased phosphorylation of MDM2 protein CTD PMID:15625077 Mdm2 Mouse simvastatin multiple interactions ISO MDM2 (Homo sapiens) 6480464 Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]] CTD PMID:15625077 Mdm2 Mouse sirolimus multiple interactions ISO MDM2 (Homo sapiens) 6480464 EIF4E protein inhibits the reaction [Sirolimus results in decreased expression of MDM2 protein]; Sirolimus inhibits more ... CTD PMID:15625077|PMID:19560264|PMID:21245298 Mdm2 Mouse sirolimus decreases expression ISO MDM2 (Homo sapiens) 6480464 Sirolimus results in decreased expression of MDM2 protein CTD PMID:19560264 Mdm2 Mouse sodium arsenate increases expression EXP 6480464 sodium arsenate results in increased expression of MDM2 mRNA CTD PMID:11353140 Mdm2 Mouse sodium arsenite multiple interactions ISO MDM2 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased expression of MDM2 protein]; [sodium arsenite more ... CTD PMID:20375080|PMID:23192986|PMID:28785074|PMID:39836092 Mdm2 Mouse sodium arsenite affects expression ISO MDM2 (Homo sapiens) 6480464 sodium arsenite affects the expression of MDM2 mRNA CTD PMID:29319823 Mdm2 Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of MDM2 mRNA CTD PMID:11353140|PMID:20477944 Mdm2 Mouse sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of MDM2 protein CTD PMID:16166651 Mdm2 Mouse sodium arsenite increases expression ISO MDM2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of MDM2 mRNA; sodium arsenite results in increased expression more ... CTD PMID:11813266|PMID:12016162|PMID:19010883|PMID:20375080|PMID:28785074|PMID:29301061|PMID:29319823|PMID:32844245 Mdm2 Mouse sodium dichromate affects expression ISO Mdm2 (Rattus norvegicus) 6480464 sodium bichromate affects the expression of MDM2 mRNA CTD PMID:11960910|PMID:22110744 Mdm2 Mouse sodium dichromate increases expression ISO Mdm2 (Rattus norvegicus) 6480464 sodium bichromate results in increased expression of MDM2 mRNA CTD PMID:25993096 Mdm2 Mouse sorafenib increases expression ISO MDM2 (Homo sapiens) 6480464 sorafenib results in increased expression of MDM2 mRNA CTD PMID:26409325 Mdm2 Mouse staurosporine multiple interactions ISO MDM2 (Homo sapiens) 6480464 Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein more ... CTD PMID:15542774 Mdm2 Mouse succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of MDM2 mRNA CTD PMID:26378955 Mdm2 Mouse sunitinib increases expression ISO MDM2 (Homo sapiens) 6480464 Sunitinib results in increased expression of MDM2 mRNA CTD PMID:31533062 Mdm2 Mouse T-2 toxin increases expression ISO Mdm2 (Rattus norvegicus) 6480464 T-2 Toxin results in increased expression of MDM2 mRNA CTD PMID:26141394 Mdm2 Mouse T-2 toxin increases expression ISO MDM2 (Homo sapiens) 6480464 T-2 Toxin results in increased expression of MDM2 mRNA CTD PMID:31863870 Mdm2 Mouse tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of MDM2 mRNA CTD PMID:17555576 Mdm2 Mouse tamoxifen decreases expression ISO MDM2 (Homo sapiens) 6480464 Tamoxifen results in decreased expression of MDM2 mRNA CTD PMID:34821461 Mdm2 Mouse tanespimycin increases degradation ISO MDM2 (Homo sapiens) 6480464 tanespimycin results in increased degradation of MDM2 protein CTD PMID:17157164 Mdm2 Mouse tauroursodeoxycholic acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 ursodoxicoltaurine results in increased expression of MDM2 mRNA CTD PMID:15885361 Mdm2 Mouse tebufenpyrad increases expression ISO MDM2 (Homo sapiens) 6480464 4-chloro-N-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of MDM2 mRNA CTD PMID:33512557 Mdm2 Mouse tert-butyl hydroperoxide increases expression ISO MDM2 (Homo sapiens) 6480464 tert-Butylhydroperoxide results in increased expression of MDM2 mRNA CTD PMID:27509014 Mdm2 Mouse testosterone decreases expression EXP 6480464 Testosterone results in decreased expression of MDM2 mRNA CTD PMID:20403060 Mdm2 Mouse tetrachloromethane multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MDM2 mRNA] CTD PMID:31150632 Mdm2 Mouse tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of MDM2 mRNA CTD PMID:31919559 Mdm2 Mouse tetrachloromethane increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of MDM2 mRNA CTD PMID:31150632 Mdm2 Mouse tetraphene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of more ... CTD PMID:27858113 Mdm2 Mouse theaflavin multiple interactions EXP 6480464 [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased more ... CTD PMID:23717041 Mdm2 Mouse thioacetamide increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of MDM2 mRNA CTD PMID:18619722|PMID:22659510|PMID:23411599|PMID:25242409|PMID:26011634|PMID:34492290 Mdm2 Mouse thioacetamide increases phosphorylation ISO Mdm2 (Rattus norvegicus) 6480464 Thioacetamide results in increased phosphorylation of MDM2 protein CTD PMID:26558467 Mdm2 Mouse thymoquinone decreases expression ISO MDM2 (Homo sapiens) 6480464 thymoquinone results in decreased expression of MDM2 protein CTD PMID:31433961|PMID:34627931 Mdm2 Mouse titanium dioxide increases expression ISO MDM2 (Homo sapiens) 6480464 titanium dioxide results in increased expression of MDM2 mRNA CTD PMID:21067279 Mdm2 Mouse titanium dioxide decreases methylation EXP 6480464 titanium dioxide results in decreased methylation of MDM2 gene CTD PMID:35295148 Mdm2 Mouse topotecan increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Topotecan results in increased expression of MDM2 mRNA CTD PMID:25729387 Mdm2 Mouse topotecan multiple interactions ISO MDM2 (Homo sapiens) 6480464 [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with Topotecan] results in decreased expression of MDM2 protein CTD PMID:23376119 Mdm2 Mouse topotecan multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of MDM2 mRNA CTD PMID:25729387 Mdm2 Mouse trichloroethene affects expression EXP 6480464 Trichloroethylene affects the expression of MDM2 mRNA CTD PMID:21135412 Mdm2 Mouse trichloroethene increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of MDM2 mRNA CTD PMID:33387578 Mdm2 Mouse trichloroethene multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA CTD PMID:17905399 Mdm2 Mouse trichostatin A affects expression ISO MDM2 (Homo sapiens) 6480464 trichostatin A affects the expression of MDM2 mRNA CTD PMID:28542535 Mdm2 Mouse triphenyl phosphate increases expression ISO Mdm2 (Rattus norvegicus) 6480464 triphenyl phosphate results in increased expression of MDM2 mRNA CTD PMID:30589522 Mdm2 Mouse triphenyl phosphate affects expression ISO MDM2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of MDM2 mRNA CTD PMID:37042841 Mdm2 Mouse Triptolide increases expression EXP 6480464 triptolide results in increased expression of MDM2 mRNA CTD PMID:32835833 Mdm2 Mouse Triptolide decreases expression ISO MDM2 (Homo sapiens) 6480464 triptolide results in decreased expression of MDM2 protein CTD PMID:36990132 Mdm2 Mouse triptonide affects expression EXP 6480464 triptonide affects the expression of MDM2 mRNA CTD PMID:33045310 Mdm2 Mouse trovafloxacin multiple interactions EXP 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MDM2 mRNA CTD PMID:18930950 Mdm2 Mouse trovafloxacin increases expression EXP 6480464 trovafloxacin results in increased expression of MDM2 mRNA CTD PMID:35537566 Mdm2 Mouse urethane multiple interactions EXP 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of MDM2 mRNA CTD PMID:12400877 Mdm2 Mouse ursodeoxycholic acid multiple interactions ISO Mdm2 (Rattus norvegicus) 6480464 [Ursodeoxycholic Acid promotes the reaction [TP53 protein binds to MDM2 protein]] which results in increased more ... CTD PMID:14514686|PMID:15222754|PMID:17881359 Mdm2 Mouse ursodeoxycholic acid increases expression ISO Mdm2 (Rattus norvegicus) 6480464 Ursodeoxycholic Acid results in increased expression of MDM2 mRNA CTD PMID:15885361 Mdm2 Mouse ursodeoxycholic acid multiple interactions ISO MDM2 (Homo sapiens) 6480464 MDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased ubiquitination of TP53 protein] CTD PMID:20807506 Mdm2 Mouse valdecoxib increases expression ISO Mdm2 (Rattus norvegicus) 6480464 valdecoxib results in increased expression of MDM2 mRNA CTD PMID:24136188 Mdm2 Mouse valproic acid increases expression ISO MDM2 (Homo sapiens) 6480464 Valproic Acid results in increased expression of MDM2 mRNA CTD PMID:23179753 Mdm2 Mouse valproic acid decreases expression ISO MDM2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of MDM2 mRNA CTD PMID:28001369 Mdm2 Mouse valproic acid affects expression ISO MDM2 (Homo sapiens) 6480464 Valproic Acid affects the expression of MDM2 mRNA CTD PMID:25979313 Mdm2 Mouse vincristine increases expression ISO MDM2 (Homo sapiens) 6480464 Vincristine results in increased expression of MDM2 mRNA CTD PMID:23649840 Mdm2 Mouse vincristine decreases expression ISO MDM2 (Homo sapiens) 6480464 Vincristine results in decreased expression of MDM2 mRNA CTD PMID:16001973 Mdm2 Mouse vorinostat decreases expression ISO MDM2 (Homo sapiens) 6480464 vorinostat results in decreased expression of MDM2 mRNA CTD PMID:27188386 Mdm2 Mouse wortmannin multiple interactions ISO MDM2 (Homo sapiens) 6480464 wortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein]; wortmannin promotes the more ... CTD PMID:17935137 Mdm2 Mouse zidovudine increases expression ISO MDM2 (Homo sapiens) 6480464 Zidovudine results in increased expression of MDM2 protein CTD PMID:16797627 Mdm2 Mouse zinc acetate multiple interactions ISO MDM2 (Homo sapiens) 6480464 motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] CTD PMID:16357179 Mdm2 Mouse zinc acetate increases expression ISO MDM2 (Homo sapiens) 6480464 Zinc Acetate results in increased expression of MDM2 mRNA CTD PMID:16357179 Mdm2 Mouse zinc atom multiple interactions ISO MDM2 (Homo sapiens) 6480464 Zinc binds to and results in increased folding of MDM2 protein; Zinc promotes the reaction more ... CTD PMID:16965791 Mdm2 Mouse zinc atom increases ubiquitination ISO MDM2 (Homo sapiens) 6480464 Zinc results in increased ubiquitination of MDM2 protein CTD PMID:16965791 Mdm2 Mouse zinc atom affects expression ISO MDM2 (Homo sapiens) 6480464 Zinc affects the expression of MDM2 protein CTD PMID:16636310 Mdm2 Mouse zinc pyrithione increases expression ISO MDM2 (Homo sapiens) 6480464 pyrithione zinc results in increased expression of MDM2 mRNA CTD PMID:21424779 Mdm2 Mouse zinc(0) multiple interactions ISO MDM2 (Homo sapiens) 6480464 Zinc binds to and results in increased folding of MDM2 protein; Zinc promotes the reaction more ... CTD PMID:16965791 Mdm2 Mouse zinc(0) affects expression ISO MDM2 (Homo sapiens) 6480464 Zinc affects the expression of MDM2 protein CTD PMID:16636310 Mdm2 Mouse zinc(0) increases ubiquitination ISO MDM2 (Homo sapiens) 6480464 Zinc results in increased ubiquitination of MDM2 protein CTD PMID:16965791