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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313300
Species: Mus musculus
RGD Object: Gene
Symbol: Mdm2
Name: transformed mouse 3T3 cell double minute 2
Acc ID: CHEBI:41922
Term: diethylstilbestrol
Definition: An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Chemical ID: MESH:D004054
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm2affects mutagenesisEXP 6480464CTDDiethylstilbestrol affects the mutagenesis of MDM2 genePMID:7916985
Mdm2decreases expressionEXP 6480464CTDDiethylstilbestrol results in decreased expression of MDM2 mRNAPMID:21041162
Mdm2increases expressionEXP 6480464CTDDiethylstilbestrol results in increased expression of MDM2 mRNAPMID:15545218
Mdm2increases expressionISOMdm2 (Rattus norvegicus)6480464CTDDiethylstilbestrol results in increased expression of MDM2 mRNAPMID:15890375
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