RGD Reference Report - Identifying a hyperkeratosis signature in autosomal recessive congenital ichthyosis: Mdm2 inhibition prevents hyperkeratosis in a rat ARCI model. - Rat Genome Database

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Identifying a hyperkeratosis signature in autosomal recessive congenital ichthyosis: Mdm2 inhibition prevents hyperkeratosis in a rat ARCI model.

Authors: Youssef, G  Ono, M  Brown, SJ  Kinsler, VA  Sebire, NJ  Harper, JI  O'Shaughnessy, RF 
Citation: Youssef G, etal., J Invest Dermatol. 2014 Mar;134(3):858-61. doi: 10.1038/jid.2013.374. Epub 2013 Sep 4.
RGD ID: 10412066
Pubmed: PMID:24005053   (View Abstract at PubMed)
DOI: DOI:10.1038/jid.2013.374   (Journal Full-text)

Abstract for this paper unavailable



RGD Manual Disease Annotations    Click to see Annotation Detail View

  
Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
MDM2Humanichthyosis treatmentISOMdm2 (Rattus norvegicus) RGD 
MDM2Humanichthyosis  IEP  RGD 
Mdm2Ratichthyosis treatmentIMP  RGD 
Mdm2Ratichthyosis  ISOMDM2 (Homo sapiens) RGD 
Mdm2Mouseichthyosis treatmentISOMdm2 (Rattus norvegicus) RGD 
Mdm2Mouseichthyosis  ISOMDM2 (Homo sapiens) RGD 

Objects Annotated

Genes (Rattus norvegicus)
Mdm2  (MDM2 proto-oncogene)

Genes (Mus musculus)
Mdm2  (transformed mouse 3T3 cell double minute 2)

Genes (Homo sapiens)
MDM2  (MDM2 proto-oncogene)


Additional Information