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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313300
Species: Mus musculus
RGD Object: Gene
Symbol: Mdm2
Name: transformed mouse 3T3 cell double minute 2
Acc ID: CHEBI:31175
Term: adefovir pivoxil
Definition: An organic phosphonate that is the dipivoxil ester of adefovir. A prodrug for adefovir, an HIV-1 reverse transcriptase inhibitor, adefovir pivoxil is used to treat chronic hepatitis B viral infection.
Chemical ID: MESH:C106812
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mdm2increases expressionISOMDM2 (Homo sapiens)6480464CTDadefovir dipivoxil results in increased expression of MDM2 mRNAPMID:25596134
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