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Gene: Fen1 (flap structure specific endonuclease 1) Mus musculus
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Symbol: Fen1
Name: flap structure specific endonuclease 1
Description: Exhibits DNA binding activity; metal ion binding activity; and nuclease activity. Involved in DNA repair and DNA replication. Predicted to colocalize with the nuclear chromosome, telomeric region. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human FEN1 (flap structure-specific endonuclease 1); PARTICIPATES IN base excision repair pathway; DNA replication pathway; non-homologous end joining pathway of double-strand break repair; INTERACTS WITH (+)-dexrazoxane; 1,1-dichloroethene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW538437; FEN-1; flap endonuclease 1; flap structure-specific endonuclease 1
Orthologs:
Homo sapiens (human) : FEN1 (flap structure-specific endonuclease 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Fen1 (flap structure-specific endonuclease 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fen1 (flap structure-specific endonuclease 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FEN1 (flap structure-specific endonuclease 1)
Canis lupus familiaris (dog) : FEN1 (flap structure-specific endonuclease 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fen1 (flap structure-specific endonuclease 1)
Sus scrofa (pig) : FEN1 (flap structure-specific endonuclease 1)
Chlorocebus sabaeus (green monkey) : FEN1 (flap structure-specific endonuclease 1)
Heterocephalus glaber (naked mole-rat) : Fen1 (flap structure-specific endonuclease 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1910,199,132 - 10,204,169 (-)Ensembl
GRCm381910,199,132 - 10,204,393 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371910,273,629 - 10,278,433 (-)NCBIGRCm37mm9NCBIm37
MGSCv361910,266,184 - 10,270,988 (-)NCBImm8
Celera1910,895,049 - 10,899,860 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Fen1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732680
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.