Cyp2c52-ps (cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene) - Rat Genome Database

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Gene: Cyp2c52-ps (cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene) Mus musculus
Analyze
Symbol: Cyp2c52-ps
Name: cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene
RGD ID: 2295251
MGI Page MGI
Description: ENCODES a protein that exhibits arachidonic acid 11,12-epoxygenase activity (ortholog); arachidonic acid 14,15-epoxygenase activity (ortholog); monooxygenase activity (ortholog); INVOLVED IN epoxygenase P450 pathway (ortholog); icosanoid biosynthetic process (ortholog); retinoic acid metabolic process (ortholog); PARTICIPATES IN forkhead class A signaling pathway; warfarin pharmacokinetics pathway; ASSOCIATED WITH Cardiomegaly (ortholog); Chemical and Drug Induced Liver Injury (ortholog); depressive disorder (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog); intracellular membrane-bounded organelle (ortholog); plasma membrane (ortholog); INTERACTS WITH (1->4)-beta-D-glucan; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine
Type: pseudo (Ensembl: unprocessed_pseudogene)
RefSeq Status: INFERRED
Previously known as: EG209753; Gm4762
RGD Orthologs
Human
Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,965,106 - 38,992,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1938,965,091 - 38,991,733 (+)EnsemblGRCm39 Ensembl
GRCm381938,976,662 - 39,003,627 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1938,976,647 - 39,003,289 (+)EnsemblGRCm38mm10GRCm38
MGSCv371939,051,152 - 39,078,117 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361939,041,818 - 39,068,332 (+)NCBIMGSCv36mm8
Celera1939,778,406 - 39,806,439 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1933.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
1,1,1-Trichloro-2-(4-hydroxyphenyl)-2-(4-methoxyphenyl)ethane  (ISO)
1,2-dichloroethene  (ISO)
1,4-naphthoquinone  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (ISO)
2-nitrophenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-methylcholanthrene  (ISO)
3-oxo-5beta-cholanic acid  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5,7-dihydroxy-4'-methoxyflavone  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-hydroxydiclofenac  (ISO)
5-Hydroxythalidomide  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
6-propyl-2-thiouracil  (ISO)
acenocoumarol  (ISO)
acetamide  (ISO)
acetonitrile  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (ISO)
alpha-hexachlorocyclohexane  (ISO)
alpha-naphthoflavone  (EXP)
amiodarone  (ISO)
ammonium chloride  (ISO)
amodiaquine  (ISO)
ampicillin  (ISO)
andrographolide  (ISO)
anthocyanin  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atazanavir sulfate  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
Benzo[a]pyrene-7,8-oxide  (ISO)
benzophenone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (ISO)
Bufuralol  (ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
C.I. Natural Red 20  (ISO)
cafestol  (ISO)
carvedilol  (ISO)
cefaloridine  (ISO)
chenodeoxycholic acid  (ISO)
chlorpromazine  (ISO)
chlorzoxazone  (ISO)
cholic acid  (ISO)
choline  (ISO)
cimetidine  (ISO)
ciprofloxacin  (ISO)
cisplatin  (ISO)
clofibric acid  (ISO)
clotrimazole  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dehydroepiandrosterone sulfate  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
diethyl phthalate  (ISO)
dimethyl sulfoxide  (ISO)
dipropyl phthalate  (ISO)
disulfiram  (ISO)
doxorubicin  (ISO)
dronedarone  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethylbenzene  (ISO)
ethylparaben  (ISO)
farnesol  (ISO)
fenofibrate  (ISO)
flavonoids  (ISO)
fluconazole  (ISO)
fluoxetine  (ISO)
fulvestrant  (ISO)
Furafylline  (ISO)
furan  (ISO)
gadolinium trichloride  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gemfibrozil  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
inulin  (EXP)
isoprenaline  (ISO)
kahweol  (ISO)
ketoconazole  (ISO)
kojic acid  (ISO)
L-methionine  (ISO)
lamotrigine  (ISO)
lansoprazole  (ISO)
lead nitrate  (ISO)
lithocholic acid  (ISO)
Luteolin 7-methyl ether  (ISO)
m-xylene  (ISO)
MeIQx  (ISO)
methapyrilene  (ISO)
methoxsalen  (ISO)
methoxychlor  (ISO)
methylarsonic acid  (ISO)
metronidazole  (ISO)
mitomycin C  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (ISO)
neomycin  (ISO)
nevirapine  (ISO)
nifedipine  (ISO)
Nonylphenol  (ISO)
ochratoxin A  (ISO)
oltipraz  (ISO)
oxycodone  (ISO)
ozone  (ISO)
paracetamol  (ISO)
Paraoxon-methyl  (ISO)
parathion-methyl  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenacetin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
poly(I:C)  (ISO)
polymyxin B2  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
profenofos  (ISO)
progesterone  (ISO)
propanal  (ISO)
propiconazole  (ISO)
propylbenzene  (ISO)
propylparaben  (ISO)
pyrene  (ISO)
pyrimidin-2-amine  (ISO)
quinine  (ISO)
resveratrol  (ISO)
riddelliine  (ISO)
rifampicin  (ISO)
rotenone  (ISO)
senecionine  (ISO)
sevoflurane  (ISO)
Shikonin  (ISO)
silicon dioxide  (ISO)
simazine  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sporidesmin A  (ISO)
streptozocin  (ISO)
styrene  (ISO)
styrene oxide  (ISO)
Sudan I  (ISO)
Sudan III  (ISO)
sulfaphenazole  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
taurocholic acid  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
tolbutamide  (ISO)
toluene  (ISO)
torasemide  (ISO)
trans-1,2-dichloroethene  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (ISO)
triclosan  (ISO)
triflumuron  (ISO)
trimethylarsine oxide  (ISO)
Triptolide  (ISO)
uranium atom  (ISO)
ursodeoxycholic acid  (ISO)
vancomycin  (ISO)
verapamil  (ISO)
warfarin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Differential regulation of endobiotic-oxidizing cytochromes P450 in vitamin A-deficient male rat liver. Murray M, etal., Br J Pharmacol. 2001 Dec;134(7):1487-97. doi: 10.1038/sj.bjp.0704380.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Cyp2c52-ps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391938,965,106 - 38,992,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1938,965,091 - 38,991,733 (+)EnsemblGRCm39 Ensembl
GRCm381938,976,662 - 39,003,627 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1938,976,647 - 39,003,289 (+)EnsemblGRCm38mm10GRCm38
MGSCv371939,051,152 - 39,078,117 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361939,041,818 - 39,068,332 (+)NCBIMGSCv36mm8
Celera1939,778,406 - 39,806,439 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1933.61NCBI
CYP2C18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381094,683,729 - 94,736,190 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1094,683,729 - 94,736,190 (+)EnsemblGRCh38hg38GRCh38
GRCh371096,443,486 - 96,495,947 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361096,433,368 - 96,485,514 (+)NCBINCBI36Build 36hg18NCBI36
Build 341096,433,367 - 96,485,514NCBI
Celera1090,183,344 - 90,236,039 (+)NCBICelera
Cytogenetic Map10q23.33NCBI
HuRef1090,070,045 - 90,122,767 (+)NCBIHuRef
CHM1_11096,725,017 - 96,777,714 (+)NCBICHM1_1
T2T-CHM13v2.01095,562,854 - 95,615,317 (+)NCBIT2T-CHM13v2.0
Cyp2c11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81246,175,216 - 246,211,445 (+)NCBIGRCr8
mRatBN7.21236,762,719 - 236,799,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1236,762,842 - 236,799,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1245,186,738 - 245,223,026 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01252,079,990 - 252,116,217 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01244,918,248 - 244,954,476 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01257,676,172 - 258,004,428 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1257,970,345 - 258,004,434 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01265,418,158 - 265,454,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,281,320 - 243,320,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1233,852,614 - 233,888,873 (+)NCBICelera
RH 3.4 Map11592.1RGD
Cytogenetic Map1q53NCBI

Variants

.
Variants in Cyp2c52-ps
946 total Variants

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
1301228Iba4_minduction of brown adipocytes 4 (mouse)Not determined19930571543305821Mouse
1302019Pgia23_mproteoglycan induced arthritis 23 (mouse)Not determined19978745343787602Mouse
14928311Manh85_mmandible shape 85 (mouse)191191478945914789Mouse
10413881Moe2_mmodifier of epilepsy 2 (mouse)191492301648923138Mouse
1301336Alcp23_malcohol preference locus 23 (mouse)Not determined191591260749912719Mouse
1301633Alcp24_malcohol preference locus 24 (mouse)Not determined191591260749912719Mouse
1302063Eae19_mexperimental allergic encephalomyelitis 19 (mouse)Not determined191829516252295381Mouse
1302004Lfp2_mlong free running period 2 (mouse)Not determined191829516252295381Mouse
4142343Moen2_mmodifier of engrailed QTL 2 (mouse)Not determined192023431454234461Mouse
10412251Mnp_mmodifier of Niemann Pick type C1 (mouse)Not determined192023431454234461Mouse
4141659Pbwg20_mpostnatal body weight growth 20 (mouse)Not determined192137870555378928Mouse
1558876W3q14_mweight 3 weeks QTL 14 (mouse)Not determined192231332653911504Mouse
12790634Ebm1_mEpidermolysis Bullosa modifier 1 (mouse)192498843958988439Mouse
1302123Tlsr8_mthymic lymphoma suppressor region 8 (mouse)Not determined192513600242388916Mouse
1301451Ath16_matherosclerosis 16 (mouse)Not determined192542691759427005Mouse
13506250Renmq1_mrenal mercury accumulation QTL 1 (mouse)192738559461385705Mouse
4141138Femwf11_mfemur work to failure 11 (mouse)Not determined2814034861420004Mouse
1300683Fembm7_mfemoral bone morphometry 7 (mouse)Not determined193014122461420004Mouse
1301942Pas13_mpulmonary adenoma susceptibility 13 (mouse)Not determined193014123161420004Mouse
1301410Cd8mts6_mCD8 memory T cell subset 6 (mouse)Not determined193014123161420004Mouse
1300856Nobq2_mNew Zealand obese QTL 2 (mouse)Not determined193089788061420004Mouse
1301741Lith2_mlithogenic gene 2 (mouse)Not determined193299215861420004Mouse
1301639Stnn_mstriatal neuron number (mouse)Not determined193395195261420004Mouse
4141019Tgq29_mtriglyceride QTL 29 (mouse)Not determined3459678661420004Mouse
1301479Sluc1_msusceptibility to lung cancer 1 (mouse)Not determined193601694446761521Mouse
1302170Tanidd1_mtally ho associated non-insulin dependednt diabetes mellitus 1 (mouse)Not determined193675259761420004Mouse
13504736Ifvrq6_minfluenza virus resistance QTL 6 (mouse)193690291044913949Mouse
4141650Chldq9_mcholesterol and HDL QTL 9 (mouse)Not determined193788298261420004Mouse
1301466T2dm2_mtype 2 diabetes mellitus 2 (mouse)Not determined193837605061420004Mouse


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NG_006923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC100729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000225458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1938,965,091 - 38,991,733 (+)Ensembl
GRCm38.p6 Ensembl1938,976,647 - 39,003,289 (+)Ensembl

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSMUSG00000114610 Ensembl, ENTREZGENE
MGD MGI:3716994 ENTREZGENE
NCBI Gene 209753 ENTREZGENE
PhenoGen Cyp2c52-ps PhenoGen


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-09-17 Cyp2c52-ps  cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene  Gm4762  predicted gene 4762  Symbol and/or name change 5135510 APPROVED