Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sod3 (superoxide dismutase 3, extracellular) Mus musculus
Symbol: Sod3
Name: superoxide dismutase 3, extracellular
Description: Exhibits superoxide dismutase activity. Involved in response to hypoxia. Localizes to extracellular space. Colocalizes with collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and neural ectoderm. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3); PARTICIPATES IN cardiovascular system disease pathway; diabetes mellitus pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI314465; EC-SOD; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC13799
Homo sapiens (human) : SOD3 (superoxide dismutase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sod3 (superoxide dismutase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod3 (superoxide dismutase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD3 (superoxide dismutase 3)
Canis lupus familiaris (dog) : SOD3 (superoxide dismutase 3)
Sus scrofa (pig) : SOD3 (superoxide dismutase 3)
Chlorocebus sabaeus (African green monkey) : SOD3 (superoxide dismutase 3)
Heterocephalus glaber (naked mole-rat) : Sod3 (superoxide dismutase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl552,363,791 - 52,371,418 (+)EnsemblGRCm38mm10GRCm38
GRCm38552,363,804 - 52,369,738 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37552,755,043 - 52,760,977 (+)NCBIGRCm37mm9NCBIm37
MGSCv36552,652,052 - 52,657,986 (+)NCBImm8
Celera549,732,370 - 49,738,292 (+)NCBICelera
Cytogenetic Map5C1NCBI
cM Map527.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Sod3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11331
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.