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Gene: Sod3 (superoxide dismutase 3, extracellular) Mus musculus
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Symbol: Sod3
Name: superoxide dismutase 3, extracellular
Description: Exhibits superoxide dismutase activity. Involved in response to hypoxia. Localizes to extracellular space. Colocalizes with collagen-containing extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; extraembryonic component; genitourinary system; and neural ectoderm. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3); PARTICIPATES IN cardiovascular system disease pathway; diabetes mellitus pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI314465; EC-SOD; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC13799
Orthologs:
Homo sapiens (human) : SOD3 (superoxide dismutase 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sod3 (superoxide dismutase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod3 (superoxide dismutase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD3 (superoxide dismutase 3)
Canis lupus familiaris (dog) : SOD3 (superoxide dismutase 3)
Sus scrofa (pig) : SOD3 (superoxide dismutase 3)
Chlorocebus sabaeus (African green monkey) : SOD3 (superoxide dismutase 3)
Heterocephalus glaber (naked mole-rat) : Sod3 (superoxide dismutase 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl552,363,791 - 52,371,418 (+)EnsemblGRCm38mm10GRCm38
GRCm38552,363,804 - 52,369,738 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37552,755,043 - 52,760,977 (+)NCBIGRCm37mm9NCBIm37
MGSCv36552,652,052 - 52,657,986 (+)NCBImm8
Celera549,732,370 - 49,738,292 (+)NCBICelera
Cytogenetic Map5C1NCBI
cM Map527.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sod3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11331
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.