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Gene: Phyh (phytanoyl-CoA hydroxylase) Mus musculus
Symbol: Phyh
Name: phytanoyl-CoA hydroxylase
Description: Exhibits catalytic activity. Involved in fatty acid alpha-oxidation. Localizes to the mitochondrion. Used to study Refsum disease. Human ortholog(s) of this gene implicated in Refsum disease; Zellweger syndrome; orofacial cleft; and peroxisomal disease. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; liver; and respiratory system. Orthologous to human PHYH (phytanoyl-CoA 2-hydroxylase); PARTICIPATES IN phytanic acid degradation pathway; Refsum disease pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI256161; AI265699; Lnap1; lupus nephritis-associated peptide 1; PAHX; phytanic acid oxidase; phytanoyl-CoA alpha-hydroxylase; phytanoyl-CoA dioxygenase, peroxisomal
Homo sapiens (human) : PHYH (phytanoyl-CoA 2-hydroxylase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Phyh (phytanoyl-CoA 2-hydroxylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phyh (phytanoyl-CoA 2-hydroxylase)
Pan paniscus (bonobo/pygmy chimpanzee) : PHYH (phytanoyl-CoA 2-hydroxylase)
Canis lupus familiaris (dog) : LOC478000 (phytanoyl-CoA hydroxylase-like)
Sus scrofa (pig) : PHYH (phytanoyl-CoA 2-hydroxylase)
more info ...
Related Pseudogenes: Gm3621  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3824,918,996 - 4,938,743 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3724,840,042 - 4,859,789 (+)NCBIGRCm37mm9NCBIm37
MGSCv3624,836,303 - 4,855,996 (+)NCBImm8
Celera24,874,084 - 4,893,837 (+)NCBICelera
Cytogenetic Map2 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Phyh
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731797
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.