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Gene: Fos (FBJ osteosarcoma oncogene) Mus musculus
Symbol: Fos
Name: FBJ osteosarcoma oncogene
RGD ID: 10596
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including positive regulation of osteoclast differentiation; response to muscle stretch; and skeletal muscle cell differentiation. Localizes to endoplasmic reticulum; nucleus; and transcription regulator complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and integumental system. Orthologous to human FOS (Fos proto-oncogene, AP-1 transcription factor subunit); PARTICIPATES IN endothelin signaling pathway; fibroblast growth factor signaling pathway; forkhead class A signaling pathway; INTERACTS WITH (20R)-protopanaxadiol; (R)-noradrenaline; (S)-amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: c-f; c-fos; cellular oncogene fos; cF; cFos; D12Rfj; D12Rfj1; proto-oncogene c-Fos; proto-oncogene protein c-fos
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391285,520,664 - 85,524,048 (+)NCBI
GRCm381285,473,890 - 85,477,274 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1285,473,890 - 85,477,273 (+)EnsemblGRCm38mm10GRCm38
MGSCv371286,814,851 - 86,818,219 (+)NCBIGRCm37mm9NCBIm37
MGSCv361286,363,004 - 86,366,372 (+)NCBImm8
Celera1286,933,225 - 86,936,593 (+)NCBICelera
Cytogenetic Map12D2NCBI
cM Map1239.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations