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Gene: Defb1 (defensin beta 1) Mus musculus
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Symbol: Defb1
Name: defensin beta 1
Description: Involved in innate immune response and response to bacterium. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and lung disease. Is expressed in epidermis and skin. Orthologous to human DEFB1 (defensin beta 1); INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW260221; BD-1; beta-defensin 1; defensin, beta 1; mBD-1
Orthologs:
Homo sapiens (human) : DEFB1 (defensin beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Defb1 (defensin beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102004444 (beta-defensin 1-like)
Pan paniscus (bonobo/pygmy chimpanzee) : DEFB1 (defensin beta 1)
Canis lupus familiaris (dog) : DEFB1 (defensin beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Defb1 (defensin beta 1)
Sus scrofa (pig) : DEFB1 (defensin beta 1)
Chlorocebus sabaeus (green monkey) : DEFB1 (defensin beta 1)
Heterocephalus glaber (naked mole-rat) : Defb1 (defensin beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl821,776,599 - 21,795,185 (+)Ensembl
GRCm38821,776,555 - 21,795,185 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37822,887,027 - 22,905,657 (+)NCBIGRCm37mm9NCBIm37
MGSCv36823,242,144 - 23,260,730 (+)NCBImm8
Celera823,268,826 - 23,284,384 (+)NCBICelera
Cytogenetic Map8 A2NCBI
cM Map810.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Defb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732690
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.