Runx1 (runt related transcription factor 1) - Rat Genome Database

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Gene: Runx1 (runt related transcription factor 1) Mus musculus
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Symbol: Runx1
Name: runt related transcription factor 1
RGD ID: 736527
MGI Page MGI
Description: Exhibits DNA-binding transcription factor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and repressing transcription factor binding activity. Involved in several processes, including animal organ development; regulation of alpha-beta T cell differentiation; and regulation of gene expression. Localizes to basement membrane and nucleus. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human RUNX1 (RUNX family transcription factor 1); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; acute myeloid leukemia pathway; chronic myeloid leukemia pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: acute myeloid leukemia 1 protein; AI462102; AM; AML1; CBF-alpha-2; Cbfa; Cbfa2; core binding factor alpha 2; core-binding factor subunit alpha-2; oncogene AML-1; PEA2-alpha B; Pebp; PEBP2-alpha B; Pebp2a2; Pebpa2b; polyomavirus enhancer-binding protein 2 alpha B subunit; runt domain, alpha subunit 2; runt-related transcription factor 1; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor alpha B subunit
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391692,398,354 - 92,622,962 (-)NCBIGRCm39mm39
GRCm39 Ensembl1692,398,354 - 92,623,037 (-)Ensembl
GRCm381692,601,466 - 92,826,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1692,601,466 - 92,826,149 (-)EnsemblGRCm38mm10GRCm38
MGSCv371692,601,711 - 92,826,311 (-)NCBIGRCm37mm9NCBIm37
MGSCv361692,492,963 - 92,586,187 (-)NCBImm8
Celera1693,683,427 - 93,779,296 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1653.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute lymphoblastic leukemia  (ISO)
acute megakaryocytic leukemia  (IMP)
acute myeloid leukemia  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (IEP)
anaplastic ependymoma  (ISO)
asthma  (ISO)
autoimmune disease  (IMP)
B-lymphoblastic leukemia/lymphoma  (ISO)
blood platelet disease  (ISO)
Bone Fractures  (ISO)
cardiomyopathy  (ISO)
colon signet ring adenocarcinoma  (ISO)
colorectal adenocarcinoma  (ISO)
colorectal cancer  (ISO)
endometrial cancer  (ISO)
endometriosis  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Leukemia  (IMP)
Familial Platelet Disorder with Associated Myeloid Malignancy  (ISO)
glioblastoma  (ISO)
hemorrhagic disease  (ISO)
hepatocellular carcinoma  (ISO)
Intestinal Neoplasms  (IMP)
intrahepatic cholangiocarcinoma  (ISO)
juvenile myelomonocytic leukemia  (ISO)
long QT syndrome 6  (ISO)
lung adenocarcinoma  (ISO)
lung non-small cell carcinoma  (ISO)
Lymphatic Metastasis  (ISO)
lymphoid leukemia  (ISO)
Mammary Neoplasms, Experimental  (ISO)
middle cerebral artery infarction  (ISO)
multicentric Castleman disease  (ISO)
multiple myeloma  (ISO)
myelodysplastic syndrome  (ISO)
myeloid neoplasm  (IMP)
pancytopenia  (ISO)
Parkinson's disease 20  (ISO)
pilocytic astrocytoma  (ISO)
platelet storage pool deficiency  (ISO)
Prostatic Neoplasms  (ISO)
rheumatoid arthritis  (ISO)
sciatic neuropathy  (IEP)
Spina Bifida Cystica  (ISO)
stomach cancer  (ISO)
T-cell acute lymphoblastic leukemia  (IMP,ISO)
T-Cell Lymphoma  (IMP)
Therapy-related Acute Myeloid Leukemia  (ISO)
thrombocytopenia  (IMP,ISO)
thyroid gland papillary carcinoma  (ISO)
transient myeloproliferative syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-cotinine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
asbestos  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
beryllium sulfate  (ISO)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
butanal  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chloroacetaldehyde  (ISO)
chlorpromazine  (ISO)
choline  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
colforsin daropate hydrochloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
cyclosporin A  (ISO)
DDE  (ISO)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
etoposide  (ISO)
folic acid  (EXP)
hydroxyurea  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP)
lead nitrate  (EXP)
leflunomide  (ISO)
malathion  (ISO)
medroxyprogesterone acetate  (ISO)
metformin  (ISO)
methapyrilene  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP,ISO)
permethrin  (ISO)
quercetin  (ISO)
serpentine asbestos  (EXP,ISO)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
Soman  (ISO)
tamibarotene  (ISO)
tamoxifen  (EXP,ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
topotecan  (ISO)
trichloroethene  (EXP)
triptonide  (EXP)
troglitazone  (ISO)
tungsten  (EXP)
Tungsten carbide  (ISO)
undecane  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
behavioral response to pain  (IMP)
cellular response to transforming growth factor beta stimulus  (IDA)
central nervous system development  (IMP)
chondrocyte differentiation  (IBA)
definitive hemopoiesis  (IMP)
embryonic hemopoiesis  (IMP)
hair follicle morphogenesis  (IMP)
hemopoiesis  (IBA,ISO,TAS)
in utero embryonic development  (IMP)
liver development  (IMP)
myeloid cell differentiation  (ISO)
myeloid leukocyte differentiation  (ISO)
myeloid progenitor cell differentiation  (IMP)
negative regulation of CD4-positive, alpha-beta T cell differentiation  (IDA)
negative regulation of cell population proliferation  (IMP)
negative regulation of granulocyte differentiation  (ISO)
negative regulation of transcription by RNA polymerase II  (IDA)
negative regulation of transcription, DNA-templated  (IDA)
neuron development  (IMP)
neuron differentiation  (IBA,IMP)
neuron fate commitment  (IMP)
ossification  (IBA)
ovulation  (ISO)
positive regulation of angiogenesis  (IMP)
positive regulation of CD8-positive, alpha-beta T cell differentiation  (IDA)
positive regulation of cell maturation  (IMP)
positive regulation of granulocyte differentiation  (ISO)
positive regulation of interferon-gamma production  (IDA)
positive regulation of interleukin-2 production  (IMP,ISO)
positive regulation of progesterone secretion  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,ISO)
positive regulation of transcription, DNA-templated  (IDA,ISO)
regulation of cell differentiation  (IBA)
regulation of hair follicle cell proliferation  (IMP)
regulation of signal transduction  (IMP)
regulation of T cell anergy  (IMP)
regulation of transcription by RNA polymerase II  (IBA)
regulation of transcription, DNA-templated  (IDA,IMP)
response to denervation involved in regulation of muscle adaptation  (ISO)
response to retinoic acid  (IDA)
skeletal system development  (IMP)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal angiogenesis  (IAGP)
abnormal axillary lymph node morphology  (IAGP)
abnormal axon morphology  (IAGP)
abnormal B cell differentiation  (IAGP)
abnormal blood cell morphology  (IAGP)
abnormal bone marrow cell morphology/development  (IAGP)
abnormal bone marrow cell physiology  (IAGP)
abnormal bone mineralization  (IAGP)
abnormal CD4-positive T cell differentiation  (IAGP)
abnormal CD8-positive, alpha-beta T cell differentiation  (IAGP)
abnormal cell physiology  (IAGP)
abnormal chondrocyte differentiation  (IAGP)
abnormal coat appearance  (IAGP)
abnormal common myeloid progenitor cell morphology  (IAGP)
abnormal definitive hematopoiesis  (IAGP)
abnormal dorsal aorta morphology  (IAGP)
abnormal double-positive T cell morphology  (IAGP)
abnormal embryonic hematopoiesis  (IAGP)
abnormal erythrocyte morphology  (IAGP)
abnormal erythroid lineage cell morphology  (IAGP)
abnormal erythroid progenitor cell morphology  (IAGP)
abnormal erythropoiesis  (IAGP)
abnormal granulocyte differentiation  (IAGP)
abnormal hematopoietic cell number  (IAGP)
abnormal hematopoietic stem cell morphology  (IAGP)
abnormal hematopoietic system morphology/development  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal inguinal lymph node morphology  (IAGP)
abnormal interferon secretion  (IAGP)
abnormal leukocyte morphology  (IAGP)
abnormal leukopoiesis  (IAGP)
abnormal liver morphology  (IAGP)
abnormal liver parenchyma morphology  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lymph node size  (IAGP)
abnormal lymph organ development  (IAGP)
abnormal mechanoreceptor morphology  (IAGP)
abnormal megakaryocyte differentiation  (IAGP)
abnormal megakaryocyte morphology  (IAGP)
abnormal megakaryocyte progenitor cell morphology  (IAGP)
abnormal myeloblast morphology/development  (IAGP)
abnormal myeloid cell morphology  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal pericyte morphology  (IAGP)
abnormal Peyer's patch morphology  (IAGP)
abnormal platelet morphology  (IAGP)
abnormal sensory neuron innervation pattern  (IAGP)
abnormal skeleton development  (IAGP)
abnormal skeleton morphology  (IAGP)
abnormal spleen B cell follicle morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal spleen white pulp morphology  (IAGP)
abnormal sternum morphology  (IAGP)
abnormal sympathetic neuron physiology  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell subpopulation ratio  (IAGP)
abnormal thymus corticomedullary boundary morphology  (IAGP)
abnormal thymus lobule morphology  (IAGP)
abnormal thymus medulla morphology  (IAGP)
abnormal tumor morphology  (IAGP)
abnormal vascular branching morphogenesis  (IAGP)
abnormal vitelline vascular remodeling  (IAGP)
abnormal xiphoid process morphology  (IAGP)
abnormal zigzag hair morphology  (IAGP)
absent sternum  (IAGP)
anemia  (IAGP)
aneurysm  (IAGP)
arrested T cell differentiation  (IAGP)
decreased B cell number  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone marrow cell number  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased common myeloid progenitor cell number  (IAGP)
decreased curvature of zigzag hairs  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased erythrocyte cell number  (IAGP)
decreased erythroid progenitor cell number  (IAGP)
decreased hematocrit  (IAGP)
decreased hematopoietic cell number  (IAGP)
decreased hematopoietic stem cell number  (IAGP)
decreased immature B cell number  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased mean corpuscular volume  (IAGP)
decreased megakaryocyte cell number  (IAGP)
decreased Peyer's patch number  (IAGP)
decreased pre-pro B cell number  (IAGP)
decreased sensory neuron number  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased spleen white pulp amount  (IAGP)
decreased T cell number  (IAGP)
decreased thymocyte number  (IAGP)
decreased thymus weight  (IAGP)
dilated vasculature  (IAGP)
embryo tissue necrosis  (IAGP)
embryonic lethality  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged liver  (IAGP)
enlarged spleen  (IAGP)
extramedullary hematopoiesis  (IAGP)
hemopericardium  (IAGP)
hemoperitoneum  (IAGP)
hemorrhage  (IAGP)
hypoalgesia  (IAGP)
impaired hematopoiesis  (IAGP)
impaired myelopoiesis  (IAGP)
increased acute promyelocytic leukemia incidence  (IAGP)
increased CD4-positive, alpha beta T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased chronic myelocytic leukemia incidence  (IAGP)
increased curvature of auchene hairs  (IAGP)
increased double-negative T cell number  (IAGP)
increased double-positive T cell number  (IAGP)
increased erythrocyte cell number  (IAGP)
increased granulocyte number  (IAGP)
increased hematopoietic stem cell number  (IAGP)
increased hemoglobin content  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased leukocyte cell number  (IAGP)
increased liver weight  (IAGP)
increased lymphoma incidence  (IAGP)
increased macrophage cell number  (IAGP)
increased mast cell number  (IAGP)
increased mature B cell number  (IAGP)
increased mean platelet volume  (IAGP)
increased metastatic potential  (IAGP)
increased monocyte cell number  (IAGP)
increased myeloid cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased nucleated erythrocyte cell number  (IAGP)
increased number of Howell-Jolly bodies  (IAGP)
increased pro-B cell number  (IAGP)
increased red blood cell distribution width  (IAGP)
increased sarcoma incidence  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased spleen red pulp amount  (IAGP)
increased spleen weight  (IAGP)
increased T cell derived lymphoma incidence  (IAGP)
increased thymocyte apoptosis  (IAGP)
increased tumor incidence  (IAGP)
internal hemorrhage  (IAGP)
intracranial hemorrhage  (IAGP)
intraventricular hemorrhage  (IAGP)
lethality throughout fetal growth and development, complete penetrance  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
lung inflammation  (IAGP)
myeloid hyperplasia  (IAGP)
neonatal lethality  (IAGP)
no abnormal phenotype detected  (IAGP)
pale liver  (IAGP)
pallor  (IAGP)
postnatal growth retardation  (IAGP)
postnatal lethality  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
skin edema  (IAGP)
slow postnatal weight gain  (IAGP)
small Peyer's patches  (IAGP)
small spleen  (IAGP)
small thymus  (IAGP)
spinal hemorrhage  (IAGP)
spleen hyperplasia  (IAGP)
thrombocytopenia  (IAGP)
thrombocytosis  (IAGP)
thymus cysts  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
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Additional References at PubMed
PMID:1720541   PMID:2249771   PMID:7607689   PMID:7609063   PMID:7647375   PMID:7774816   PMID:7835892   PMID:7862157   PMID:8035830   PMID:8164679   PMID:8384306   PMID:8395054  
PMID:8437866   PMID:8497254   PMID:8537354   PMID:8565077   PMID:8575770   PMID:8622955   PMID:8929538   PMID:9054947   PMID:9159135   PMID:9199349   PMID:9233771   PMID:9234595  
PMID:9558367   PMID:9794229   PMID:9811459   PMID:10075931   PMID:10207087   PMID:10207104   PMID:10219254   PMID:10226014   PMID:10228168   PMID:10340392   PMID:10349636   PMID:10610183  
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PMID:11217851   PMID:11243869   PMID:11257229   PMID:11265752   PMID:11375505   PMID:11483356   PMID:11673502   PMID:11731260   PMID:12049718   PMID:12086889   PMID:12091336   PMID:12093746  
PMID:12217689   PMID:12218099   PMID:12376107   PMID:12417632   PMID:12464175   PMID:12466851   PMID:12466854   PMID:12466855   PMID:12477932   PMID:12495904   PMID:12509458   PMID:12551949  
PMID:12617847   PMID:12665593   PMID:12732184   PMID:12794114   PMID:12796513   PMID:12807882   PMID:12807883   PMID:12811823   PMID:12835475   PMID:12917624   PMID:12946863   PMID:14504086  
PMID:14507780   PMID:14516670   PMID:14525762   PMID:14630789   PMID:14681479   PMID:14747476   PMID:14752096   PMID:14966519   PMID:15030765   PMID:15034051   PMID:15070703   PMID:15123671  
PMID:15136142   PMID:15155459   PMID:15156179   PMID:15240886   PMID:15253936   PMID:15271791   PMID:15297309   PMID:15355562   PMID:15361869   PMID:15389629   PMID:15514019   PMID:15592512  
PMID:15618518   PMID:15713794   PMID:15728845   PMID:15737933   PMID:15749889   PMID:15778374   PMID:15780989   PMID:15828028   PMID:15870195   PMID:15882575   PMID:15914564   PMID:15928041  
PMID:15963785   PMID:16007221   PMID:16024660   PMID:16026391   PMID:16046550   PMID:16059634   PMID:16081688   PMID:16105979   PMID:16141072   PMID:16141073   PMID:16174759   PMID:16214126  
PMID:16247465   PMID:16281942   PMID:16314494   PMID:16338472   PMID:16429136   PMID:16446141   PMID:16446142   PMID:16496309   PMID:16602821   PMID:16675540   PMID:16702405   PMID:16761014  
PMID:16783647   PMID:16890157   PMID:17011173   PMID:17038514   PMID:17108004   PMID:17142326   PMID:17159898   PMID:17199045   PMID:17208218   PMID:17213321   PMID:17290219   PMID:17360569  
PMID:17377529   PMID:17377532   PMID:17431131   PMID:17431401   PMID:17476283   PMID:17503961   PMID:17533052   PMID:17553423   PMID:17626615   PMID:17646405   PMID:17646406   PMID:17823240  
PMID:17823307   PMID:17901249   PMID:17908929   PMID:17964124   PMID:17972914   PMID:17994017   PMID:18037485   PMID:18039856   PMID:18171930   PMID:18184866   PMID:18227350   PMID:18250229  
PMID:18256199   PMID:18258917   PMID:18261462   PMID:18275068   PMID:18287559   PMID:18354160   PMID:18371450   PMID:18385258   PMID:18427115   PMID:18439490   PMID:18528438   PMID:18594778  
PMID:18671852   PMID:18684862   PMID:18687690   PMID:18759297   PMID:18768464   PMID:18776905   PMID:18799693   PMID:18849990   PMID:18984863   PMID:19000669   PMID:19036704   PMID:19041779  
PMID:19090621   PMID:19124003   PMID:19129762   PMID:19151769   PMID:19182774   PMID:19218012   PMID:19269865   PMID:19321859   PMID:19328795   PMID:19339695   PMID:19384951   PMID:19419310  
PMID:19450519   PMID:19464215   PMID:19470763   PMID:19544462   PMID:19570513   PMID:19592096   PMID:19647224   PMID:19703295   PMID:19767756   PMID:19800266   PMID:19801444   PMID:19858498  
PMID:19865483   PMID:19917773   PMID:20007544   PMID:20008790   PMID:20035012   PMID:20059953   PMID:20096094   PMID:20102410   PMID:20139099   PMID:20152828   PMID:20181744   PMID:20187849  
PMID:20194037   PMID:20195544   PMID:20206228   PMID:20308320   PMID:20385820   PMID:20430957   PMID:20478528   PMID:20484411   PMID:20534675   PMID:20554972   PMID:20628604   PMID:20637190  
PMID:20647008   PMID:20660741   PMID:20673362   PMID:20699440   PMID:20711984   PMID:20711992   PMID:20844136   PMID:20876651   PMID:20887958   PMID:20966214   PMID:21059642   PMID:21085653  
PMID:21122804   PMID:21151104   PMID:21170035   PMID:21178013   PMID:21267068   PMID:21292764   PMID:21356387   PMID:21435585   PMID:21464233   PMID:21469119   PMID:21474713   PMID:21498670  
PMID:21505195   PMID:21518930   PMID:21576367   PMID:21677750   PMID:21734270   PMID:21757616   PMID:21786422   PMID:21795542   PMID:21807129   PMID:21813676   PMID:21865554   PMID:21873191  
PMID:21873635   PMID:21873977   PMID:21906677   PMID:21911838   PMID:21937700   PMID:22016185   PMID:22021368   PMID:22040971   PMID:22128334   PMID:22145044   PMID:22169307   PMID:22253804  
PMID:22315423   PMID:22318233   PMID:22325351   PMID:22326227   PMID:22366949   PMID:22370763   PMID:22392989   PMID:22395608   PMID:22411870   PMID:22412390   PMID:22431360   PMID:22431569  
PMID:22451420   PMID:22531928   PMID:22554697   PMID:22558218   PMID:22560297   PMID:22565823   PMID:22611151   PMID:22665574   PMID:22693452   PMID:22759635   PMID:22787056   PMID:22801375  
PMID:22863011   PMID:22895712   PMID:22912405   PMID:22919028   PMID:22922362   PMID:22984619   PMID:23064151   PMID:23122290   PMID:23135987   PMID:23213481   PMID:23228968   PMID:23254331  
PMID:23325226   PMID:23335233   PMID:23378040   PMID:23438573   PMID:23481257   PMID:23487742   PMID:23532528   PMID:23537631   PMID:23555309   PMID:23555640   PMID:23604320   PMID:23623899  
PMID:23639725   PMID:23645839   PMID:23679839   PMID:23704093   PMID:23717578   PMID:23823022   PMID:23830984   PMID:23840778   PMID:23861879   PMID:23922928   PMID:23924635   PMID:23979164  
PMID:24030384   PMID:24037986   PMID:24058535   PMID:24095735   PMID:24098673   PMID:24146773   PMID:24198358   PMID:24240679   PMID:24310293   PMID:24316076   PMID:24326267   PMID:24462289  
PMID:24505141   PMID:24509477   PMID:24516396   PMID:24553180   PMID:24582971   PMID:24583642   PMID:24606124   PMID:24632399   PMID:24677539   PMID:24736457   PMID:24771859   PMID:24798493  
PMID:24855208   PMID:24903482   PMID:24952961   PMID:25061103   PMID:25066130   PMID:25082880   PMID:25139355   PMID:25139854   PMID:25150295   PMID:25185713   PMID:25262822   PMID:25290738  
PMID:25369838   PMID:25410786   PMID:25415051   PMID:25468972   PMID:25516969   PMID:25605286   PMID:25645944   PMID:25689854   PMID:25742748   PMID:25762373   PMID:25802202   PMID:25831528  
PMID:25834056   PMID:25847244   PMID:25896884   PMID:25902481   PMID:25995324   PMID:26001080   PMID:26010396   PMID:26053522   PMID:26073082   PMID:26091038   PMID:26091714   PMID:26165925  
PMID:26204127   PMID:26205084   PMID:26206133   PMID:26269126   PMID:26275053   PMID:26350416   PMID:26418744   PMID:26418893   PMID:26460546   PMID:26473321   PMID:26494788   PMID:26545946  
PMID:26598521   PMID:26707936   PMID:26745853   PMID:26808730   PMID:26890219   PMID:26892431   PMID:26916619   PMID:26919255   PMID:26923596   PMID:26952982   PMID:26992132   PMID:27020276  
PMID:27056890   PMID:27076172   PMID:27076431   PMID:27105579   PMID:27124577   PMID:27133822   PMID:27143755   PMID:27145737   PMID:27210758   PMID:27239041   PMID:27267711   PMID:27329940  
PMID:27376470   PMID:27389484   PMID:27457419   PMID:27480124   PMID:27543859   PMID:27570068   PMID:27573239   PMID:27634876   PMID:27713544   PMID:27719760   PMID:27802172   PMID:27819671  
PMID:27869314   PMID:27879203   PMID:27880904   PMID:27913297   PMID:28031476   PMID:28065741   PMID:28213513   PMID:28314106   PMID:28322735   PMID:28400392   PMID:28476948   PMID:28490570  
PMID:28630052   PMID:28637900   PMID:28644396   PMID:28650479   PMID:28743859   PMID:28744012   PMID:28765611   PMID:28790107   PMID:28807942   PMID:28827394   PMID:28869683   PMID:28877240  
PMID:28945245   PMID:28951542   PMID:29030345   PMID:29031500   PMID:29038474   PMID:29045838   PMID:29047338   PMID:29093060   PMID:29107070   PMID:29222089   PMID:29300724   PMID:29324888  
PMID:29330113   PMID:29361566   PMID:29438697   PMID:29523786   PMID:29530939   PMID:29555646   PMID:29674496   PMID:29733873   PMID:29759484   PMID:29768404   PMID:29773646   PMID:29866654  
PMID:29924977   PMID:29938858   PMID:29973370   PMID:29991720   PMID:30026553   PMID:30046048   PMID:30185787   PMID:30208304   PMID:30212841   PMID:30300583   PMID:30322915   PMID:30332630  
PMID:30391350   PMID:30409784   PMID:30683858   PMID:30850344   PMID:30877169   PMID:30917309   PMID:31032403   PMID:31113964   PMID:31171577   PMID:31289995   PMID:31343406   PMID:31409672  
PMID:31624376   PMID:31712577   PMID:31769548   PMID:31773180   PMID:31801063   PMID:31818882   PMID:32098917   PMID:32221845   PMID:32259484   PMID:32319515   PMID:32341038   PMID:32499402  
PMID:32571873   PMID:32572036   PMID:32817592   PMID:32826903   PMID:32878886   PMID:32883883   PMID:32929473   PMID:33025905   PMID:33476325  


Genomics

Comparative Map Data
Runx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391692,398,354 - 92,622,962 (-)NCBIGRCm39mm39
GRCm39 Ensembl1692,398,354 - 92,623,037 (-)Ensembl
GRCm381692,601,466 - 92,826,074 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1692,601,466 - 92,826,149 (-)EnsemblGRCm38mm10GRCm38
MGSCv371692,601,711 - 92,826,311 (-)NCBIGRCm37mm9NCBIm37
MGSCv361692,492,963 - 92,586,187 (-)NCBImm8
Celera1693,683,427 - 93,779,296 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1653.7NCBI
RUNX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2134,787,801 - 36,004,667 (-)EnsemblGRCh38hg38GRCh38
GRCh382134,787,801 - 35,049,334 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372136,160,098 - 36,421,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map21q22.12NCBI
HuRef2121,639,088 - 21,900,490 (-)NCBIHuRef
CHM1_12135,722,384 - 35,983,819 (-)NCBICHM1_1
Runx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21131,839,880 - 32,074,427 (-)NCBI
Rnor_6.0 Ensembl1132,769,165 - 33,003,021 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01132,765,147 - 33,003,061 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01136,367,315 - 36,601,674 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41132,623,461 - 32,725,404 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11132,679,703 - 32,781,647 (-)NCBI
Celera1131,494,069 - 31,582,728 (-)NCBICelera
RH 3.4 Map11214.7RGD
Cytogenetic Map11q11NCBI
RUNX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13130,170,859 - 30,420,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3130,170,605 - 30,420,839 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3129,270,454 - 29,519,721 (-)NCBI
ROS_Cfam_1.03129,472,070 - 29,721,306 (-)NCBI
UMICH_Zoey_3.13129,337,954 - 29,586,748 (-)NCBI
UNSW_CanFamBas_1.03129,353,308 - 29,602,472 (-)NCBI
UU_Cfam_GSD_1.03129,843,623 - 30,092,833 (-)NCBI
RUNX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13198,371,835 - 198,638,189 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113198,371,835 - 198,635,648 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213208,205,560 - 208,304,379 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
03.MMHAP38FRA9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,648,404 - 92,648,577UniSTSGRCm38
MGSCv371692,648,649 - 92,648,822UniSTSGRCm37
Celera1693,730,320 - 93,730,493UniSTS
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Whitehead_YAC16 UniSTS
11.MMHAP83FRD8.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,784,438 - 92,784,637UniSTSGRCm38
MGSCv371692,784,683 - 92,784,882UniSTSGRCm37
Celera1693,867,650 - 93,867,849UniSTS
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Whitehead_YAC16 UniSTS
D26532  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,605,369 - 92,605,564UniSTSGRCm38
MGSCv371692,605,614 - 92,605,809UniSTSGRCm37
Celera1693,687,367 - 93,687,562UniSTS
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Whitehead_YAC16 UniSTS
D16Mit128  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,646,457 - 92,646,578UniSTSGRCm38
MGSCv371692,646,702 - 92,646,823UniSTSGRCm37
Celera1693,728,364 - 93,728,487UniSTS
Cytogenetic Map16C4UniSTS
cM Map1666.3UniSTS
Whitehead Genetic1650.3UniSTS
Whitehead/MRC_RH16984.18UniSTS
Whitehead_YAC16 UniSTS
D16Mit51  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,775,966 - 92,776,120UniSTSGRCm38
MGSCv371692,776,211 - 92,776,365UniSTSGRCm37
Celera1693,859,104 - 93,859,260UniSTS
Cytogenetic Map16C4UniSTS
cM Map1666.75UniSTS
Whitehead/MRC_RH16984.18UniSTS
D16Mit52  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,676,374 - 92,676,489UniSTSGRCm38
MGSCv371692,676,619 - 92,676,734UniSTSGRCm37
Celera1693,758,249 - 93,758,364UniSTS
Cytogenetic Map16C4UniSTS
cM Map1666.8UniSTS
Whitehead Genetic1651.4UniSTS
Whitehead_YAC16 UniSTS
AI462102  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,696,673 - 92,696,768UniSTSGRCm38
MGSCv371692,696,918 - 92,697,013UniSTSGRCm37
Celera1693,778,641 - 93,778,736UniSTS
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Whitehead/MRC_RH16978.73UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371692,604,956 - 92,605,631UniSTSGRCm37
Celera1693,686,702 - 93,687,384UniSTS
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
cM Map1662.2UniSTS
cM Map1662.2UniSTS
cM Map1662.2UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,695,671 - 92,695,962UniSTSGRCm38
MGSCv371692,695,916 - 92,696,207UniSTSGRCm37
Celera1693,777,639 - 93,777,930UniSTS
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C4UniSTS
cM Map1662.2UniSTS
Runx1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381692,604,711 - 92,605,386UniSTSGRCm38
MGSCv371692,604,956 - 92,605,631UniSTSGRCm37
Celera1693,686,702 - 93,687,384UniSTS
Cytogenetic Map16C4UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163562627392776120Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166181175695811876Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6318975897189758Mouse
1300928Etia_methanol induced activation (mouse)Not determined166351701997517128Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166353044897530584Mouse
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166880383498207768Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166927924498207768Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166933072398207768Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166933072398207768Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166933072398207768Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166945759498207768Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167058336498207768Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir199a-1mmu-miR-199a-3pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19114653
Mir30c-1mmu-miR-30c-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19114653
Mir27ammu-miR-27a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19114653
Mir27ammu-miR-27a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI19298589
Mir27ammu-miR-27a-3pTarbaseexternal_infoReporter GenePOSITIVE
Mir27ammu-miR-27a-3pTarbaseexternal_infoWesternblitPOSITIVE
Mir18mmu-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19114653
Mir9-3mmu-miR-9-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19114653
Mir126ammu-miR-126a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI21163928
Mir27bmmu-miR-27b-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blot//Functional MTI19298589
Mir27bmmu-miR-27b-3pTarbaseexternal_infoReporter GenePOSITIVE
Mir27bmmu-miR-27b-3pTarbaseexternal_infoWesternblitPOSITIVE
Mir30c-2mmu-miR-30c-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blotFunctional MTI19114653

Predicted Target Of
Summary Value
Count of predictions:4607
Count of miRNA genes:732
Interacting mature miRNAs:984
Transcripts:ENSMUST00000023673, ENSMUST00000113956, ENSMUST00000168195
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001111022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001111023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF193030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF345649 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI462102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK165307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL672278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC069929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF135151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ033862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB056658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT025774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D13802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D26531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D26532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  W29200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X97306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000023673   ⟹   ENSMUSP00000023673
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,601,466 - 92,826,149 (-)Ensembl
RefSeq Acc Id: ENSMUST00000113956   ⟹   ENSMUSP00000109589
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,603,656 - 92,697,328 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168195   ⟹   ENSMUSP00000131079
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,605,398 - 92,696,125 (-)Ensembl
RefSeq Acc Id: ENSMUST00000186296   ⟹   ENSMUSP00000140419
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,695,592 - 92,825,778 (-)Ensembl
RefSeq Acc Id: ENSMUST00000187242   ⟹   ENSMUSP00000139819
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,686,758 - 92,695,495 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189126
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,686,989 - 92,697,325 (-)Ensembl
RefSeq Acc Id: ENSMUST00000189679
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1692,815,428 - 92,826,074 (-)Ensembl
RefSeq Acc Id: NM_001111021   ⟹   NP_001104491
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391692,398,354 - 92,622,962 (-)NCBI
GRCm381692,601,466 - 92,826,074 (-)NCBI
MGSCv371692,601,711 - 92,826,311 (-)RGD
Celera1693,683,427 - 93,779,297 (-)NCBI
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001111022   ⟹   NP_001104492
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391692,398,354 - 92,622,962 (-)NCBI
GRCm381692,601,466 - 92,826,074 (-)NCBI
MGSCv371692,601,711 - 92,826,311 (-)RGD
Celera1693,683,427 - 93,779,297 (-)NCBI
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001111023   ⟹   NP_001104493
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391692,398,354 - 92,494,217 (-)NCBI
GRCm381692,601,466 - 92,697,329 (-)NCBI
MGSCv371692,601,711 - 92,826,311 (-)RGD
Celera1693,683,427 - 93,779,297 (-)NCBI
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_009821   ⟹   NP_033951
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391692,398,354 - 92,494,217 (-)NCBI
GRCm381692,601,466 - 92,697,329 (-)NCBI
MGSCv371692,601,711 - 92,826,311 (-)RGD
Celera1693,683,427 - 93,779,297 (-)NCBI
cM Map16 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033951   ⟸   NM_009821
- Peptide Label: isoform 4
- UniProtKB: G3X9W7 (UniProtKB/TrEMBL),   Q8BQ09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104493   ⟸   NM_001111023
- Peptide Label: isoform 3
- UniProtKB: G3UWD2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104491   ⟸   NM_001111021
- Peptide Label: isoform 1
- UniProtKB: Q3UM65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001104492   ⟸   NM_001111022
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: ENSMUSP00000109589   ⟸   ENSMUST00000113956
RefSeq Acc Id: ENSMUSP00000140419   ⟸   ENSMUST00000186296
RefSeq Acc Id: ENSMUSP00000131079   ⟸   ENSMUST00000168195
RefSeq Acc Id: ENSMUSP00000139819   ⟸   ENSMUST00000187242
RefSeq Acc Id: ENSMUSP00000023673   ⟸   ENSMUST00000023673
Protein Domains
Runt

Promoters
RGD ID:6847322
Promoter ID:MM_ACW:21281
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   ES_Cell
Transcripts:RUNX1.FSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361692,606,071 - 92,606,667 (-)MPROMDB
RGD ID:6827482
Promoter ID:MM_KWN:21762
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001111023,   NM_009821,   UC007ZZH.1,   UC007ZZL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361692,695,771 - 92,698,437 (-)MPROMDB
RGD ID:13674484
Promoter ID:EPDNEW_M21391
Type:multiple initiation site
Name:Runx1_1
Description:Mus musculus runt related transcription factor 1 , transcriptvariant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21392  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381692,697,325 - 92,697,385EPDNEW
RGD ID:13674486
Promoter ID:EPDNEW_M21392
Type:initiation region
Name:Runx1_2
Description:Mus musculus runt related transcription factor 1 , transcriptvariant 4, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M21391  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381692,826,043 - 92,826,103EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99852 AgrOrtholog
Ensembl Genes ENSMUSG00000022952 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000023673 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000109589 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000131079 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000139819 UniProtKB/TrEMBL
  ENSMUSP00000140419 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000023673 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000113956 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000168195 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000186296 UniProtKB/TrEMBL
  ENSMUST00000187242 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.770.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AML1_Runt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53-like_TF_DNA-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  p53/RUNT-type_TF_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Runt_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Runx_central_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RunxI_C_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TF_Runt-rel_RUNX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12394 UniProtKB/TrEMBL
MGD MGI:99852 ENTREZGENE
NCBI Gene 12394 ENTREZGENE
PANTHER PTHR11950 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Runt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RunxI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB RUNX1 RGD
PhenoGen Runx1 PhenoGen
PIRSF TF_Runt-rel_RUNX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ONCOGENEAML1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE RUNT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49417 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WPL0_MOUSE UniProtKB/TrEMBL
  A0A087WR05_MOUSE UniProtKB/TrEMBL
  G3UWD2 ENTREZGENE, UniProtKB/TrEMBL
  G3X9W7 ENTREZGENE, UniProtKB/TrEMBL
  Q03347 ENTREZGENE
  Q3UM65 ENTREZGENE, UniProtKB/TrEMBL
  Q6NSS1_MOUSE UniProtKB/TrEMBL
  Q8BQ09 ENTREZGENE, UniProtKB/TrEMBL
  RUNX1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary O08598 UniProtKB/Swiss-Prot
  Q62049 UniProtKB/Swiss-Prot
  Q9ESB9 UniProtKB/Swiss-Prot
  Q9ET65 UniProtKB/Swiss-Prot