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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Vrk3 | Mouse | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of VRK3 mRNA | CTD | PMID:22206623 | Vrk3 | Mouse | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of VRK3 mRNA | CTD | PMID:22206623 | Vrk3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | VRK3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of VRK3 mRNA | CTD | PMID:22298810 | Vrk3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of VRK3 mRNA | CTD | PMID:20106945 and PMID:21632981 | Vrk3 | Mouse | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of VRK3 mRNA | CTD | PMID:21570461 | Vrk3 | Mouse | 2,4-dinitrotoluene | affects expression | ISO | Vrk3 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of VRK3 mRNA | CTD | PMID:21346803 | Vrk3 | Mouse | 3,3',4,4',5-pentachlorobiphenyl | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | 3 more ... | CTD | PMID:19692669 | Vrk3 | Mouse | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of VRK3 mRNA | CTD | PMID:28628672 | Vrk3 | Mouse | afimoxifene | decreases response to substance | ISO | VRK3 (Homo sapiens) | 6480464 | VRK3 results in decreased susceptibility to afimoxifene | CTD | PMID:21233418 | Vrk3 | Mouse | aflatoxin B1 | increases methylation | ISO | VRK3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of VRK3 gene and Aflatoxin B1 results in increased methylation of VRK3 intron | CTD | PMID:27153756 and PMID:30157460 | Vrk3 | Mouse | Aflatoxin B2 alpha | decreases methylation | ISO | VRK3 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of VRK3 intron | CTD | PMID:30157460 | Vrk3 | Mouse | amosite asbestos | decreases methylation | ISO | VRK3 (Homo sapiens) | 6480464 | Asbestos and Amosite results in decreased methylation of VRK3 promoter | CTD | PMID:29626692 | Vrk3 | Mouse | benzo[a]pyrene | increases methylation | ISO | VRK3 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of VRK3 promoter | CTD | PMID:27901495 | Vrk3 | Mouse | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of VRK3 mRNA | CTD | PMID:23798566 | Vrk3 | Mouse | bisphenol A | affects expression | ISO | Vrk3 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of VRK3 mRNA | CTD | PMID:25181051 | Vrk3 | Mouse | bisphenol F | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of VRK3 mRNA | CTD | PMID:28628672 | Vrk3 | Mouse | caffeine | decreases phosphorylation | ISO | VRK3 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of VRK3 protein | CTD | PMID:35688186 | Vrk3 | Mouse | CGP 52608 | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to VRK3 gene] | CTD | PMID:28238834 | Vrk3 | Mouse | cisplatin | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of VRK3 mRNA | CTD | PMID:27392435 | Vrk3 | Mouse | clofibric acid | multiple interactions | ISO | Vrk3 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of VRK3 mRNA | CTD | PMID:17602206 | Vrk3 | Mouse | cobalt dichloride | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of VRK3 mRNA | CTD | PMID:19320972 | Vrk3 | Mouse | crocidolite asbestos | decreases methylation | ISO | VRK3 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased methylation of VRK3 promoter | CTD | PMID:29626692 | Vrk3 | Mouse | cyclosporin A | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of VRK3 mRNA | CTD | PMID:27989131 | Vrk3 | Mouse | dexamethasone | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of VRK3 mRNA | CTD | PMID:28628672 | Vrk3 | Mouse | doxorubicin | decreases expression | ISO | VRK3 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of VRK3 mRNA | CTD | PMID:29803840 | Vrk3 | Mouse | fenthion | decreases expression | EXP | | 6480464 | Fenthion results in decreased expression of VRK3 mRNA | CTD | PMID:34813904 | Vrk3 | Mouse | folic acid | multiple interactions | EXP | | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of VRK3 mRNA | CTD | PMID:22206623 | Vrk3 | Mouse | FR900359 | affects phosphorylation | ISO | VRK3 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of VRK3 protein | CTD | PMID:37730182 | Vrk3 | Mouse | gentamycin | decreases expression | ISO | Vrk3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of VRK3 mRNA | CTD | PMID:33387578 | Vrk3 | Mouse | indometacin | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of VRK3 mRNA | CTD | PMID:28628672 | Vrk3 | Mouse | methidathion | decreases expression | EXP | | 6480464 | methidathion results in decreased expression of VRK3 mRNA | CTD | PMID:34813904 | Vrk3 | Mouse | methoxychlor | affects methylation | ISO | Vrk3 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of VRK3 gene | CTD | PMID:35440735 | Vrk3 | Mouse | N,N-diethyl-m-toluamide | multiple interactions | ISO | Vrk3 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of VRK3 gene | CTD | PMID:33148267 | Vrk3 | Mouse | N-nitrosodiethylamine | multiple interactions | ISO | Vrk3 (Rattus norvegicus) | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of VRK3 mRNA | CTD | PMID:17602206 | Vrk3 | Mouse | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of VRK3 mRNA | CTD | PMID:17562736 | Vrk3 | Mouse | paracetamol | increases expression | ISO | Vrk3 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of VRK3 mRNA | CTD | PMID:33387578 | Vrk3 | Mouse | paracetamol | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of VRK3 mRNA | CTD | PMID:22230336 | Vrk3 | Mouse | permethrin | multiple interactions | ISO | Vrk3 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of VRK3 gene | CTD | PMID:33148267 | Vrk3 | Mouse | resveratrol | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of VRK3 mRNA | CTD | PMID:23557933 | Vrk3 | Mouse | serpentine asbestos | decreases methylation | ISO | VRK3 (Homo sapiens) | 6480464 | Asbestos and Serpentine results in decreased methylation of VRK3 promoter | CTD | PMID:29626692 | Vrk3 | Mouse | sodium arsenite | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of VRK3 mRNA | CTD | PMID:38568856 | Vrk3 | Mouse | thioacetamide | decreases expression | ISO | Vrk3 (Rattus norvegicus) | 6480464 | Thioacetamide results in decreased expression of VRK3 mRNA | CTD | PMID:34492290 | Vrk3 | Mouse | triphenyl phosphate | affects expression | ISO | VRK3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of VRK3 mRNA | CTD | PMID:37042841 | Vrk3 | Mouse | triptonide | decreases expression | EXP | | 6480464 | triptonide results in decreased expression of VRK3 mRNA | CTD | PMID:33045310 | Vrk3 | Mouse | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of VRK3 mRNA | CTD | PMID:17292431 | Vrk3 | Mouse | valproic acid | affects expression | ISO | VRK3 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of VRK3 mRNA | CTD | PMID:25979313 | Vrk3 | Mouse | valproic acid | increases expression | ISO | VRK3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of VRK3 mRNA | CTD | PMID:23179753 | Vrk3 | Mouse | zinc atom | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of VRK3 mRNA | CTD | PMID:18593933 | Vrk3 | Mouse | zinc(0) | multiple interactions | ISO | VRK3 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of VRK3 mRNA | CTD | PMID:18593933 | |