Itpr3 (inositol 1,4,5-triphosphate receptor 3) - Rat Genome Database

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Gene: Itpr3 (inositol 1,4,5-triphosphate receptor 3) Mus musculus
Analyze
Symbol: Itpr3
Name: inositol 1,4,5-triphosphate receptor 3
RGD ID: 10822
MGI Page MGI
Description: Exhibits inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity and phosphatidylinositol binding activity. Involved in several processes, including calcium ion transport into cytosol; long-term synaptic potentiation; and sensory perception of taste. Localizes to endoplasmic reticulum membrane; nucleolus; and nucleoplasm. Is expressed in several structures, including jaw; liver; sensory organ; skeleton; and spleen. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ITPR3 (inositol 1,4,5-trisphosphate receptor type 3); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's disease pathway; INTERACTS WITH 1,1-dichloroethene; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: inositol 1,4,5-trisphosphate receptor type 3; insP3R3; Ip; IP3 receptor; IP3R 3; Ip3r3; Itp; Itpr-3; tf; type 3 inositol 1,4,5-trisphosphate receptor; type 3 InsP3 receptor
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391727,275,976 - 27,341,197 (+)NCBIGRCm39mm39
GRCm39 Ensembl1727,276,278 - 27,341,197 (+)Ensembl
GRCm381727,057,002 - 27,122,223 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,057,304 - 27,122,223 (+)EnsemblGRCm38mm10GRCm38
MGSCv371727,194,249 - 27,259,168 (+)NCBIGRCm37mm9NCBIm37
MGSCv361726,785,125 - 26,849,812 (+)NCBImm8
Celera1727,593,736 - 27,658,505 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-butoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (ISO)
Adenophostin A  (ISO)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
C60 fullerene  (ISO)
cadmium dichloride  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
choline  (EXP)
cisplatin  (EXP,ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (EXP)
dichlorine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (EXP)
fenvalerate  (EXP,ISO)
fipronil  (ISO)
flavonoids  (ISO)
folic acid  (EXP)
genistein  (ISO)
glyphosate  (ISO)
Heptachlor epoxide  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (EXP)
leflunomide  (ISO)
linsidomine  (ISO)
menadione  (ISO)
methotrexate  (ISO)
methoxychlor  (ISO)
monosodium L-glutamate  (EXP)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP)
pirinixic acid  (EXP)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
streptozocin  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
titanium dioxide  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tungsten  (EXP)
undecane  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (ISO)
XL147  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal allogrooming behavior  (IAGP)
abnormal brain commissure morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal coat/ hair morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal feces composition  (IAGP)
abnormal food intake  (IAGP)
abnormal gustatory system physiology  (IAGP)
abnormal hair cycle  (IEA)
abnormal hair growth  (IAGP)
abnormal intramembranous bone ossification  (IAGP)
abnormal liquid preference  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal neocortex morphology  (IAGP)
abnormal pancreas secretion  (IAGP)
abnormal pancreatic acinar cell morphology  (IAGP)
abnormal salivary gland physiology  (IAGP)
abnormal social investigation  (IAGP)
abnormal vocalization  (IAGP)
absent corpus callosum  (IAGP)
decreased anterior commissure size  (IAGP)
decreased anxiety-related response  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased bone mineral content  (IAGP)
decreased circulating glucose level  (IAGP)
decreased hippocampal commissure size  (IAGP)
decreased salivation  (IAGP)
dystonia  (IAGP)
excessive vocalization  (IAGP)
impaired hearing  (IAGP)
impaired social transmission of food preference  (IAGP)
increased body weight  (IAGP)
increased defecation amount  (IAGP)
increased fluid intake  (IAGP)
increased grooming behavior  (IAGP)
increased growth rate  (IAGP)
kinked tail  (IAGP)
low sweet preference  (IAGP)
neurodegeneration  (IAGP)
no abnormal phenotype detected  (IAGP)
pancreatic acinar cell zymogen granule accumulation  (IAGP)
paralysis  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
small ears  (IAGP)
sparse hair  (IEA)
steatorrhea  (IAGP)
transmission ratio distortion  (IEA)
weight loss  (IAGP)
References

Additional References at PubMed
PMID:458159   PMID:924142   PMID:1225760   PMID:1350556   PMID:1374893   PMID:1643311   PMID:1665374   PMID:1676981   PMID:1794044   PMID:2911572   PMID:2981632   PMID:3036643  
PMID:3197958   PMID:3455895   PMID:3909941   PMID:3996911   PMID:5309548   PMID:5647630   PMID:5906493   PMID:6096010   PMID:6321339   PMID:6509553   PMID:6510705   PMID:6684996  
PMID:6816725   PMID:6857276   PMID:7074682   PMID:7276510   PMID:7390155   PMID:7589801   PMID:7749235   PMID:7829069   PMID:7894168   PMID:8063813   PMID:8081710   PMID:8663526  
PMID:8690273   PMID:9013981   PMID:9065779   PMID:9309177   PMID:9585437   PMID:9808793   PMID:9858485   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11132407   PMID:11149946  
PMID:11217851   PMID:11703504   PMID:11860456   PMID:11934702   PMID:12421829   PMID:12466851   PMID:12477932   PMID:12606813   PMID:12904583   PMID:12953786   PMID:14167577   PMID:14610273  
PMID:15489334   PMID:15632133   PMID:15713744   PMID:15747579   PMID:15890645   PMID:16014380   PMID:16141072   PMID:16141073   PMID:16195467   PMID:16352659   PMID:16840702   PMID:16844763  
PMID:16899052   PMID:17327232   PMID:17374359   PMID:17379641   PMID:17416589   PMID:17559418   PMID:17581770   PMID:17890015   PMID:17925404   PMID:18194433   PMID:18241669   PMID:18417102  
PMID:18547250   PMID:18728777   PMID:18799693   PMID:19033399   PMID:19050248   PMID:19068129   PMID:19343206   PMID:19419429   PMID:19528657   PMID:19692655   PMID:20071408   PMID:20075939  
PMID:20345893   PMID:20519450   PMID:20618443   PMID:20668922   PMID:20813840   PMID:20843799   PMID:20888890   PMID:20958798   PMID:21030605   PMID:21040460   PMID:21055421   PMID:21150295  
PMID:21267068   PMID:21382375   PMID:21420385   PMID:21424589   PMID:21435446   PMID:21436055   PMID:21568942   PMID:21600960   PMID:21655085   PMID:21799730   PMID:21873635   PMID:22056750  
PMID:22100909   PMID:22101175   PMID:22495310   PMID:22539775   PMID:22561129   PMID:22562042   PMID:22572820   PMID:22677272   PMID:22992961   PMID:23100490   PMID:23341217   PMID:23382219  
PMID:23392696   PMID:23463619   PMID:23516531   PMID:23859941   PMID:23884412   PMID:24062633   PMID:24428937   PMID:24656250   PMID:24872539   PMID:24901844   PMID:24912134   PMID:25088363  
PMID:25215520   PMID:25300468   PMID:25737585   PMID:25803479   PMID:25852455   PMID:25879444   PMID:26037800   PMID:26193638   PMID:26234751   PMID:26300749   PMID:26562433   PMID:27349290  
PMID:27378338   PMID:27460706   PMID:27514653   PMID:27515175   PMID:27568557   PMID:27777977   PMID:27910949   PMID:28190767   PMID:28419336   PMID:28578927   PMID:28615414   PMID:28860523  
PMID:29276054   PMID:29315582   PMID:29330412   PMID:29395920   PMID:30196744   PMID:30590033   PMID:30786075   PMID:31522074   PMID:32123907   PMID:32294408   PMID:32325033   PMID:32385093  


Genomics

Comparative Map Data
Itpr3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391727,275,976 - 27,341,197 (+)NCBIGRCm39mm39
GRCm39 Ensembl1727,276,278 - 27,341,197 (+)Ensembl
GRCm381727,057,002 - 27,122,223 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1727,057,304 - 27,122,223 (+)EnsemblGRCm38mm10GRCm38
MGSCv371727,194,249 - 27,259,168 (+)NCBIGRCm37mm9NCBIm37
MGSCv361726,785,125 - 26,849,812 (+)NCBImm8
Celera1727,593,736 - 27,658,505 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.68NCBI
ITPR3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl633,620,365 - 33,696,574 (+)EnsemblGRCh38hg38GRCh38
GRCh38633,621,322 - 33,696,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37633,589,099 - 33,664,339 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,697,139 - 33,772,329 (+)NCBINCBI36hg18NCBI36
Build 34633,697,321 - 33,772,317NCBI
Celera635,143,559 - 35,218,741 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef633,330,927 - 33,406,007 (+)NCBIHuRef
CHM1_1633,591,516 - 33,666,641 (+)NCBICHM1_1
Itpr3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2205,136,968 - 5,202,339 (+)NCBI
Rnor_6.0 Ensembl205,646,097 - 5,711,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0205,645,894 - 5,711,702 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,711,508 - 7,775,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4205,292,430 - 5,357,502 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1205,292,656 - 5,357,727 (+)NCBI
Celera206,717,488 - 6,781,775 (+)NCBICelera
Cytogenetic Map20p12NCBI
Itpr3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554372,055,805 - 2,106,076 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554372,055,782 - 2,106,709 (+)NCBIChiLan1.0ChiLan1.0
ITPR3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1634,303,454 - 34,378,220 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl634,303,454 - 34,378,215 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0633,194,531 - 33,269,788 (+)NCBIMhudiblu_PPA_v0panPan3
ITPR3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,970,613 - 3,050,254 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,805,187 - 3,048,938 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,997,254 - 3,066,455 (+)NCBI
ROS_Cfam_1.0123,313,122 - 3,382,514 (+)NCBI
UMICH_Zoey_3.1122,980,128 - 3,049,212 (+)NCBI
UNSW_CanFamBas_1.0123,061,183 - 3,130,533 (+)NCBI
UU_Cfam_GSD_1.0123,159,323 - 3,228,541 (+)NCBI
Itpr3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,641,843 - 38,705,335 (+)NCBI
SpeTri2.0NW_00493647625,254,937 - 25,318,316 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITPR3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl729,835,898 - 29,902,160 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1729,835,922 - 29,901,305 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2734,443,858 - 34,509,094 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ITPR3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11738,381,862 - 38,456,505 (-)NCBI
ChlSab1.1 Ensembl1738,381,743 - 38,456,499 (-)Ensembl
Itpr3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475423,228,690 - 23,281,552 (-)NCBI

Position Markers
PMC275467P4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381727,120,975 - 27,121,517UniSTSGRCm38
MGSCv371727,257,920 - 27,258,462UniSTSGRCm37
Celera1727,657,263 - 27,657,805UniSTS
Cytogenetic Map17A3.3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17128979566Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17128979566Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17128979566Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17130809908Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17480447727496965Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17765701129268449Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse
11081168Tir7_mtrypanosome infection response 7 (mouse)171390439847904522Mouse
1300914Pcir4_mperiosteal circumference 4 (mouse)Not determined171484267848842786Mouse
1558886Lgth9_mbody length 9 (mouse)Not determined171484267848842786Mouse
1302070Tbbmd7_mtotal body bone mineral density 7 (mouse)Not determined171484267848842786Mouse
1300995Fembrs4_mfemur breaking strength 4 (mouse)Not determined171484267848842786Mouse
1302140Wta4_mweight adult 4 (mouse)Not determined171660074750600869Mouse
1302152Skull25_mskull morphology 25 (mouse)Not determined171660074750600869Mouse
1301505Tir1_mtrypanosome infection response 1 (mouse)Not determined171660074750600869Mouse
1302038Radpf1_mradiation pulmonary fibrosis 1 (mouse)Not determined171661519333600869Mouse
10412083Sm2_msusceptibility to Schistosoma mansoni infection 2 (mouse)Not determined171681096950811104Mouse
1302042Acsns3_mAngiostrongylus costaricensis nematode susceptibility 3 (mouse)Not determined171724323451243371Mouse
1300535Char3_mP. chabaudi malaria resistance QTL 3 (mouse)Not determined171724323451243371Mouse
10412214Sxbq3_mSGC/Knj cross B6 QTL 3 (mouse)Not determined171724323451243371Mouse
13452396Leusq3_mleucocytosis susceptibility QTL 3 (mouse)171724323451243371Mouse
13452399Leusq6_mleucocytosis susceptibility QTL 6 (mouse)171724323451243371Mouse
1301840Ssial4_msusceptibility to sialadenitiss 4 (mouse)Not determined171795643651959238Mouse
1301331Lbw1_mlupus NZB x NZW 1 (mouse)Not determined171819938152202007Mouse
1301056Pas2_mpulmonary adenoma susceptibility 2 (mouse)Not determined171820316552205351Mouse
15039354Nmrs36_mNAFLD-associated magnetic resonance shift 36 (mouse)171883413352834133Mouse
1301454Eae5_msusceptibility to experimental allergic encephalomyelitis 5 (mouse)Not determined172430185958301973Mouse
10412198Sst5_msusceptibility to tuberculosis 5 (mouse)Not determined172485760955405969Mouse
10412196Bbaa28_mB.burgdorferi-associated arthritis 28 (mouse)Not determined172536594043665344Mouse
12903990Opfaq5_mopen field activity QTL 5 (mouse)172573195128773124Mouse
10412204Bbaa29_mB.burgdorferi-associated arthritis 29 (mouse)Not determined172574029459740461Mouse
1558758Kcal2_mkilocalorie 2 (mouse)Not determined172618203852604676Mouse
1300602Eye2_meye weight 2 (mouse)Not determined172628636340794146Mouse
1302005Loco2_mlocomotor activity 2 (mouse)Not determined172657408160574223Mouse
12904013Cfq12_mconditioned fear QTL 12 (mouse)172660980730445981Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:334
Count of miRNA genes:261
Interacting mature miRNAs:283
Transcripts:ENSMUST00000049308
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000049308   ⟹   ENSMUSP00000038150
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1727,057,304 - 27,122,223 (+)Ensembl
RefSeq Acc Id: ENSMUST00000235521
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1727,106,177 - 27,107,349 (+)Ensembl
RefSeq Acc Id: NM_080553   ⟹   NP_542120
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391727,276,278 - 27,341,197 (+)NCBI
GRCm381727,057,304 - 27,122,223 (+)NCBI
MGSCv371727,194,249 - 27,259,168 (+)RGD
Celera1727,593,736 - 27,658,505 (+)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523712   ⟹   XP_006523775
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391727,275,976 - 27,341,197 (+)NCBI
GRCm381727,057,002 - 27,122,223 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036160338   ⟹   XP_036016231
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391727,318,067 - 27,341,197 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_542120   ⟸   NM_080553
- UniProtKB: P70227 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006523775   ⟸   XM_006523712
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000038150   ⟸   ENSMUST00000049308
RefSeq Acc Id: XP_036016231   ⟸   XM_036160338
- Peptide Label: isoform X2
Protein Domains
Ion_trans   MIR   RIH_assoc

Promoters
RGD ID:13675280
Promoter ID:EPDNEW_M21789
Type:multiple initiation site
Name:Itpr3_1
Description:Mus musculus inositol 1,4,5-triphosphate receptor 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381727,057,300 - 27,057,360EPDNEW
RGD ID:6828256
Promoter ID:MM_KWN:22717
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_080553,   OTTMUST00000077694
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361727,193,251 - 27,194,422 (+)MPROMDB
RGD ID:6847406
Promoter ID:MM_ACW:22183
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:ITPR3.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361727,247,736 - 27,248,236 (+)MPROMDB
RGD ID:6847407
Promoter ID:MM_ACW:22184
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:ITPR3.CSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361727,253,019 - 27,253,519 (+)MPROMDB
RGD ID:6847408
Promoter ID:MM_ACW:22185
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:ITPR3.DSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361727,255,616 - 27,256,116 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96624 AgrOrtholog
Ensembl Genes ENSMUSG00000042644 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000038150 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000049308 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Ins145_P3_rcpt UniProtKB/Swiss-Prot
  InsP3_rcpt UniProtKB/Swiss-Prot
  Ion_trans_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot
  MIR_motif UniProtKB/Swiss-Prot
  RIH_assoc-dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIH_dom UniProtKB/Swiss-Prot
  RyR/IP3R_RIH_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:16440 UniProtKB/Swiss-Prot
MGD MGI:96624 ENTREZGENE
NCBI Gene 16440 ENTREZGENE
Pfam Ins145_P3_rec UniProtKB/Swiss-Prot
  Ion_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR UniProtKB/Swiss-Prot
  RIH_assoc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RYDR_ITPR UniProtKB/Swiss-Prot
PhenoGen Itpr3 PhenoGen
PRINTS INSP3RECEPTR UniProtKB/Swiss-Prot
PROSITE MIR UniProtKB/Swiss-Prot
SMART MIR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF100909 UniProtKB/Swiss-Prot
  SSF82109 UniProtKB/Swiss-Prot
UniProt ITPR3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q0IJ80_MOUSE UniProtKB/TrEMBL
  Q922U9_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q5DWM4 UniProtKB/Swiss-Prot
  Q8CED5 UniProtKB/Swiss-Prot
  Q91Z08 UniProtKB/Swiss-Prot