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Gene: Flot1 (flotillin 1) Mus musculus
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Symbol: Flot1
Name: flotillin 1
Description: Predicted to have ionotropic glutamate receptor binding activity; protease binding activity; and protein heterodimerization activity. Involved in several processes, including positive regulation of cell-cell adhesion mediated by cadherin; positive regulation of cellular component organization; and protein kinase C signaling. Localizes to the external side of plasma membrane; flotillin complex; and sarcolemma. Predicted to colocalize with the COP9 signalosome and cortical actin cytoskeleton. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human FLOT1 (flotillin 1); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 1,1-dichloroethene; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: flotillin-1; reggie-2
Orthologs:
Homo sapiens (human) : FLOT1 (flotillin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Flot1 (flotillin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flot1 (flotillin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FLOT1 (flotillin 1)
Canis lupus familiaris (dog) : FLOT1 (flotillin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flot1 (flotillin 1)
Sus scrofa (pig) : FLOT1 (flotillin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381735,823,320 - 35,832,789 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371735,960,302 - 35,969,732 (+)NCBIGRCm37mm9NCBIm37
MGSCv361735,431,410 - 35,440,840 (+)NCBImm8
Celera1739,333,424 - 39,342,847 (+)NCBICelera
Cytogenetic Map17 B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Flot1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733800
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.