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Gene: Gstm1 (glutathione S-transferase, mu 1) Mus musculus
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Symbol: Gstm1
Name: glutathione S-transferase, mu 1
Description: Exhibits protein homodimerization activity. Involved in cellular response to drug. Localizes to the myelin sheath. Used to study autism spectrum disorder. Human ortholog(s) of this gene implicated in several diseases, including eye disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung disease (multiple); and reproductive organ cancer (multiple). Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and sensory organ. Orthologous to human GSTM1 (glutathione S-transferase mu 1) and GSTM5 (glutathione S-transferase mu 5); PARTICIPATES IN cyclophosphamide pharmacodynamics pathway; cyclophosphamide pharmacokinetics pathway; glutathione metabolic pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-lipoic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glutathione S-transferase GT8.7; glutathione S-transferase Mu 1; glutathione-S-transferase, mu 1; GST 1-1; GST class-mu 1; Gstb-1; Gstb1; pmGT10
Orthologs:
Homo sapiens (human) : GSTM1 (glutathione S-transferase mu 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gstm1 (glutathione S-transferase mu 1)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GSTM1 (glutathione S-transferase mu 1)
more info ...
Related Pseudogenes: Gstm2-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm383108,012,250 - 108,017,979 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373107,815,168 - 107,820,891 (-)NCBIGRCm37mm9NCBIm37
MGSCv363108,140,314 - 108,146,029 (-)NCBImm8
Celera3110,345,820 - 110,351,544 (-)NCBICelera
Cytogenetic Map3 F2.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gstm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10697
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.