Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Gls2 (glutaminase 2 (liver, mitochondrial)) Mus musculus
Analyze
Symbol: Gls2
Name: glutaminase 2 (liver, mitochondrial)
RGD ID: 735898
Description: Predicted to have glutaminase activity. Predicted to be involved in glutamine family amino acid metabolic process; reactive oxygen species metabolic process; and regulation of apoptotic process. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; limb; nervous system; skeleton; and urinary system. Orthologous to human GLS2 (glutaminase 2); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; argininosuccinic aciduria pathway; carbamoyl phosphate synthetase I deficiency pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: A330074B06Rik; AI195532; GA; GLS; glutaminase liver isoform, mitochondrial; KIAA4146; L; L-glutaminase; L-glutamine amidohydrolase; Lga; liver mitochondrial glutaminase
Orthologs:
Homo sapiens (human) : GLS2 (glutaminase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gls2 (glutaminase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gls2 (glutaminase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GLS2 (glutaminase 2)
Canis lupus familiaris (dog) : GLS2 (glutaminase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gls2 (glutaminase 2)
Sus scrofa (pig) : GLS2 (glutaminase 2)
Chlorocebus sabaeus (African green monkey) : GLS2 (glutaminase 2)
Heterocephalus glaber (naked mole-rat) : Gls2 (glutaminase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl10128,194,457 - 128,210,004 (+)EnsemblGRCm38mm10GRCm38
GRCm3810128,194,635 - 128,210,004 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710127,631,691 - 127,647,060 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,597,639 - 127,612,883 (+)NCBImm8
Celera10130,589,515 - 130,604,841 (+)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gls2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735898
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.