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Gene: Cd14 (CD14 antigen) Mus musculus
Symbol: Cd14
Name: CD14 antigen
Description: Predicted to have lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of cytokine production; and toll-like receptor 4 signaling pathway. Localizes to the external side of plasma membrane and membrane raft. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and perinatal necrotizing enterocolitis. Is expressed in several structures, including femur; gallbladder; intestine; reproductive system; and telencephalon. Orthologous to human CD14 (CD14 molecule).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
Homo sapiens (human) : CD14 (CD14 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd14 (CD14 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd14 (CD14 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD14 (CD14 molecule)
Canis lupus familiaris (dog) : CD14 (CD14 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd14 (CD14 molecule)
Sus scrofa (pig) : CD14 (CD14 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381836,725,064 - 36,726,815 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371836,884,721 - 36,886,308 (-)NCBIGRCm37mm9NCBIm37
MGSCv361836,851,041 - 36,852,628 (-)NCBImm8
Celera1837,177,141 - 37,178,892 (-)NCBICelera
Cytogenetic Map18 B2NCBI
cM Map1819.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cd14
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733890
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.