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Gene: Cd14 (CD14 antigen) Mus musculus
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Symbol: Cd14
Name: CD14 antigen
Description: Predicted to have lipopeptide binding activity; lipopolysaccharide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including lipopolysaccharide-mediated signaling pathway; positive regulation of cytokine production; and toll-like receptor 4 signaling pathway. Localizes to the external side of plasma membrane and membrane raft. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; artery disease (multiple); celiac disease; cystic fibrosis; and perinatal necrotizing enterocolitis. Is expressed in several structures, including femur; gallbladder; intestine; reproductive system; and telencephalon. Orthologous to human CD14 (CD14 molecule).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein
Orthologs:
Homo sapiens (human) : CD14 (CD14 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd14 (CD14 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd14 (CD14 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD14 (CD14 molecule)
Canis lupus familiaris (dog) : CD14 (CD14 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd14 (CD14 molecule)
Sus scrofa (pig) : CD14 (CD14 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381836,725,064 - 36,726,815 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371836,884,721 - 36,886,308 (-)NCBIGRCm37mm9NCBIm37
MGSCv361836,851,041 - 36,852,628 (-)NCBImm8
Celera1837,177,141 - 37,178,892 (-)NCBICelera
Cytogenetic Map18 B2NCBI
cM Map1819.46NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd14
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733890
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.