Krt18 (keratin 18) - Rat Genome Database
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Gene: Krt18 (keratin 18) Mus musculus
Analyze
Symbol: Krt18
Name: keratin 18
RGD ID: 1557581
MGI Page MGI
Description: Predicted to have scaffold protein binding activity. Involved in extrinsic apoptotic signaling pathway; hepatocyte apoptotic process; and tumor necrosis factor-mediated signaling pathway. Localizes to cell periphery and keratin filament. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT18 (keratin 18); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CK-18; CK18; cytokeratin endo B; cytokeratin-18; Endo B; K18; keratin complex 1, acidic, gene 18; keratin D; keratin, type I cytoskeletal 18; keratin-18; Krt1-1; Krt1-18
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm17847   Gm17870   Gm5200   Gm7943  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,936,651 - 101,940,461 (+)NCBIGRCm39mm39
GRCm3815102,028,216 - 102,032,026 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,028,180 - 102,032,027 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715101,858,647 - 101,862,457 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615101,856,259 - 101,860,055 (+)NCBImm8
Celera15104,183,109 - 104,186,912 (+)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(S)-colchicine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3'-diindolylmethane  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (EXP)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acrolein  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-4-oxoretinol  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
arachidonic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-carotene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
bufalin  (ISO)
buspirone  (ISO)
buta-1,3-diene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP,ISO)
chloroform  (ISO)
chromium trinitrate  (EXP)
ciguatoxin CTX1B  (EXP)
clofibrate  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
cumene  (EXP)
cylindrospermopsin  (ISO)
DDE  (ISO)
DDT  (ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP)
diethylstilbestrol  (EXP)
diiodine  (ISO)
dimercaprol  (EXP)
dimethylarsinic acid  (EXP,ISO)
dioscin  (EXP,ISO)
dioxygen  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
erythromycin estolate  (ISO)
estramustine  (ISO)
ethanol  (EXP,ISO)
fenofibrate  (EXP)
finasteride  (ISO)
fipronil  (ISO)
flavone  (ISO)
flutamide  (ISO)
folic acid  (EXP)
fructose  (ISO)
fulvestrant  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
genistein  (EXP,ISO)
glafenine  (ISO)
glutathione  (ISO)
glycidol  (ISO)
griseofulvin  (EXP,ISO)
heparin  (ISO)
hydrazine  (ISO)
indometacin  (ISO)
irinotecan  (ISO)
iron(III) nitrilotriacetate  (ISO)
isoprenaline  (EXP)
levofloxacin  (ISO)
lovastatin  (EXP)
mercury dibromide  (ISO)
methapyrilene  (ISO)
methotrexate  (EXP,ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP,ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-nitrosomorpholine  (ISO)
nefazodone  (ISO)
nevirapine  (ISO)
nickel atom  (ISO)
nystatin  (EXP)
octreotide  (ISO)
oxybenzone  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phosgene  (EXP)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
potassium chromate  (EXP)
procymidone  (ISO)
progesterone  (EXP,ISO)
pyrogallol  (EXP)
quartz  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
SB 203580  (ISO)
SB 431542  (EXP,ISO)
selenium atom  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
sodium perchlorate  (ISO)
SU6656  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thioacetamide  (EXP,ISO)
titanium dioxide  (EXP,ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
trimethylarsine oxide  (ISO)
triphenyl phosphate  (ISO)
trovafloxacin  (ISO)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
vinorelbine  (ISO)
vorinostat  (ISO)
warfarin  (EXP)

References

References - curated
1. Abdel Haleem H, etal., Arab J Gastroenterol. 2013 Jun;14(2):68-72. doi: 10.1016/j.ajg.2013.03.004. Epub 2013 Apr 28.
2. Balkan A, etal., Arab J Gastroenterol. 2017 Jun;18(2):98-103. doi: 10.1016/j.ajg.2017.05.008. Epub 2017 Jun 1.
3. Bettermann K, etal., Oncotarget. 2016 Nov 8;7(45):73309-73322. doi: 10.18632/oncotarget.12325.
4. Bratoeva K, etal., Metab Syndr Relat Disord. 2018 Sep;16(7):350-357. doi: 10.1089/met.2017.0162. Epub 2018 Jul 10.
5. Chang YH, etal., Ann Clin Biochem. 2019 Jan;56(1):141-147. doi: 10.1177/0004563218796259. Epub 2018 Aug 27.
6. Darweesh SK, etal., Eur J Gastroenterol Hepatol. 2019 May;31(5):633-641. doi: 10.1097/MEG.0000000000001385.
7. Diab DL, etal., Clin Gastroenterol Hepatol. 2008 Nov;6(11):1249-54. doi: 10.1016/j.cgh.2008.07.016. Epub 2008 Jul 26.
8. El Bassat H, etal., Arab J Gastroenterol. 2014 Mar;15(1):6-11. doi: 10.1016/j.ajg.2014.01.009. Epub 2014 Feb 7.
9. Feldstein AE, etal., Hepatology. 2009 Oct;50(4):1072-8. doi: 10.1002/hep.23050.
10. Gonsebatt ME, etal., Arch Toxicol. 2007 Sep;81(9):619-26. doi: 10.1007/s00204-007-0192-7. Epub 2007 Mar 6.
11. Hetz H, etal., J Clin Lab Anal. 2007;21(5):277-81. doi: 10.1002/jcla.20180.
12. Jazwinski AB, etal., J Viral Hepat. 2012 Apr;19(4):278-82. doi: 10.1111/j.1365-2893.2011.01546.x. Epub 2011 Nov 24.
13. Jia XF, etal., Zhonghua Gan Zang Bing Za Zhi. 2010 Nov;18(11):826-30. doi: 10.3760/cma.j.issn.1007-3418.2010.11.009.
14. Joka D, etal., Hepatology. 2012 Feb;55(2):455-64. doi: 10.1002/hep.24734. Epub 2011 Nov 29.
15. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78.
16. Ku NO, etal., J Clin Invest. 1997 Jan 1;99(1):19-23.
17. Macdonald S, etal., Hepatology. 2018 Mar;67(3):989-1002. doi: 10.1002/hep.29581. Epub 2018 Jan 24.
18. Manivannan B, etal., Infect Immun. 2011 May;79(5):2051-8. doi: 10.1128/IAI.01214-10. Epub 2011 Feb 28.
19. Masuoka HC, etal., Dig Dis Sci. 2015 Dec;60(12):3642-6. doi: 10.1007/s10620-015-3805-7. Epub 2015 Jul 21.
20. MGD data from the GO Consortium
21. MGD IEA
22. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
23. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
24. OMIM Disease Annotation Pipeline
25. Poirier C, etal., Genetics 2002 Oct;162(2):831-40.
26. RGD automated import pipeline
27. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
28. RGD automated import pipeline for gene-chemical interactions
29. Sekiguchi T, etal., PLoS One. 2015 Jun 25;10(6):e0131658. doi: 10.1371/journal.pone.0131658. eCollection 2015.
30. Shi Y, etal., Virol J. 2010 Mar 24;7:70. doi: 10.1186/1743-422X-7-70.
31. Steinert PM, etal., Nature 1983 Apr 28;302(5911):794-800.
32. Weerasinghe SV, etal., J Cell Sci. 2014 Apr 1;127(Pt 7):1464-75. doi: 10.1242/jcs.138479. Epub 2014 Jan 24.
33. Xue L, etal., Pathol Res Pract. 2018 Nov;214(11):1778-1786. doi: 10.1016/j.prp.2018.08.016. Epub 2018 Aug 20.
34. Yagmur E, etal., Clin Biochem. 2007 Jun;40(9-10):651-5. doi: 10.1016/j.clinbiochem.2006.12.010. Epub 2007 Jan 17.
35. Yetti H, etal., Life Sci. 2013 Nov 4;93(18-19):673-80. doi: 10.1016/j.lfs.2013.09.013. Epub 2013 Sep 23.
36. Yilmaz Y, etal., Med Sci Monit. 2009 Apr;15(4):CR189-93.
Additional References at PubMed
PMID:2416755   PMID:2454868   PMID:2467843   PMID:2471065   PMID:2693040   PMID:7527618   PMID:8170478   PMID:8522591   PMID:8565852   PMID:9415422   PMID:9508776   PMID:9786956  
PMID:9810706   PMID:9864371   PMID:9932492   PMID:10349636   PMID:10352021   PMID:10571739   PMID:10625605   PMID:10662643   PMID:10683172   PMID:10694432   PMID:10747083   PMID:10922068  
PMID:10925280   PMID:11013209   PMID:11042159   PMID:11062258   PMID:11076861   PMID:11197537   PMID:11204270   PMID:11217851   PMID:11296228   PMID:11321598   PMID:11732007   PMID:11917136  
PMID:12176733   PMID:12466851   PMID:12477932   PMID:12533792   PMID:12717381   PMID:12835312   PMID:14576356   PMID:15282307   PMID:15485910   PMID:15615879   PMID:15687259   PMID:15819413  
PMID:15992795   PMID:16141072   PMID:16141073   PMID:16180309   PMID:16513945   PMID:16602821   PMID:16818723   PMID:16831889   PMID:16914490   PMID:16973199   PMID:16998848   PMID:17021047  
PMID:17079275   PMID:17187062   PMID:17187412   PMID:17330888   PMID:17409114   PMID:17617404   PMID:17699753   PMID:18038450   PMID:18079413   PMID:18349119   PMID:18358466   PMID:18395095  
PMID:18425773   PMID:18478268   PMID:18554416   PMID:18824566   PMID:18941637   PMID:19002587   PMID:19073166   PMID:19397691   PMID:19407366   PMID:19494835   PMID:19562671   PMID:19737349  
PMID:19737616   PMID:19820184   PMID:19825937   PMID:19841136   PMID:19876067   PMID:19918884   PMID:20035116   PMID:20161774   PMID:20382704   PMID:20572855   PMID:20729838   PMID:20818615  
PMID:21059267   PMID:21093383   PMID:21127502   PMID:21233130   PMID:21266412   PMID:21267068   PMID:21302255   PMID:21347296   PMID:21356385   PMID:21429986   PMID:21435445   PMID:21636786  
PMID:21677159   PMID:21852401   PMID:21930775   PMID:22185794   PMID:22334478   PMID:22449798   PMID:22588720   PMID:23045527   PMID:23103586   PMID:23284756   PMID:23862017   PMID:23924630  
PMID:23993789   PMID:24131634   PMID:24367558   PMID:24449888   PMID:24457600   PMID:24586114   PMID:24672777   PMID:25179606   PMID:25468937   PMID:25601450   PMID:25617501   PMID:25882495  
PMID:26076167   PMID:26123167   PMID:26280121   PMID:26399787   PMID:26489514   PMID:26644517   PMID:26655896   PMID:26711500   PMID:26994968   PMID:27120339   PMID:27143755   PMID:27371534  
PMID:27414999   PMID:27422101   PMID:27527664   PMID:27611684   PMID:27693698   PMID:27807348   PMID:28219950   PMID:28226240   PMID:28606991   PMID:28708243   PMID:28729362   PMID:28819138  
PMID:29181608   PMID:29350066   PMID:29449449   PMID:30085028   PMID:31068622   PMID:31721615   PMID:31917811   PMID:32201259   PMID:32325033   PMID:32848249  


Genomics

Comparative Map Data
Krt18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3915101,936,651 - 101,940,461 (+)NCBIGRCm39mm39
GRCm3815102,028,216 - 102,032,026 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl15102,028,180 - 102,032,027 (+)EnsemblGRCm38mm10GRCm38
MGSCv3715101,858,647 - 101,862,457 (+)NCBIGRCm37mm9NCBIm37
MGSCv3615101,856,259 - 101,860,055 (+)NCBImm8
Celera15104,183,109 - 104,186,912 (+)NCBICelera
Cytogenetic Map15F2NCBI
cM Map1557.22NCBI
KRT18
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1252,948,871 - 52,952,906 (+)EnsemblGRCh38hg38GRCh38
GRCh381252,948,855 - 52,952,906 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371253,342,655 - 53,346,690 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361251,628,922 - 51,632,952 (+)NCBINCBI36hg18NCBI36
Build 341251,628,921 - 51,632,951NCBI
Celera1252,989,626 - 52,993,657 (+)NCBI
Cytogenetic Map12q13.13NCBI
HuRef1250,386,471 - 50,390,501 (+)NCBIHuRef
CHM1_11253,309,411 - 53,313,442 (+)NCBICHM1_1
Krt18
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07143,629,455 - 143,633,131 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7143,629,455 - 143,633,131 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07141,425,684 - 141,429,360 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.1279,988,565 - 79,989,008 (+)NCBI
Celera7129,594,039 - 129,597,715 (+)NCBICelera
Cytogenetic Map7q36NCBI
Krt18
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955458226,805 - 232,728 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955458227,017 - 230,752 (+)NCBIChiLan1.0ChiLan1.0
KRT18
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11236,587,149 - 36,591,196 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1236,587,149 - 36,591,196 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01235,807,660 - 35,811,691 (-)NCBIMhudiblu_PPA_v0panPan3
KRT18
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl272,189,269 - 2,193,368 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1272,189,269 - 2,193,368 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Krt18
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493651210,290,706 - 10,294,647 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT18
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl518,217,691 - 18,222,833 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1518,217,686 - 18,221,432 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2518,726,205 - 18,729,755 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KRT18
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11149,073,733 - 49,081,706 (+)NCBI
Krt18
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249041,011,675 - 1,015,319 (+)NCBI

Position Markers
Krt18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3813117,458,068 - 117,458,805UniSTSGRCm38
MGSCv3713118,246,875 - 118,247,612UniSTSGRCm37
Celera13121,863,389 - 121,864,126UniSTS
Cytogenetic Map15F3UniSTS
Cytogenetic Map13D2.3UniSTS
cM Map1558.86UniSTS
cM Map1558.86UniSTS
D15Mit40  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815102,029,302 - 102,029,441UniSTSGRCm38
MGSCv3715101,859,733 - 101,859,872UniSTSGRCm37
Celera15104,184,188 - 104,184,327UniSTS
Cytogenetic Map15F3UniSTS
cM Map1565.0UniSTS
Whitehead Genetic1565.6UniSTS
Whitehead/MRC_RH15923.07UniSTS
Krt2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815102,027,754 - 102,027,828UniSTSGRCm38
MGSCv3715101,858,185 - 101,858,259UniSTSGRCm37
Celera15104,182,647 - 104,182,721UniSTS
Cytogenetic Map15F3UniSTS
cM Map1558.7UniSTS
Krt2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3815102,029,336 - 102,029,447UniSTSGRCm38
MGSCv3715101,859,767 - 101,859,878UniSTSGRCm37
Celera15104,184,222 - 104,184,333UniSTS
Cytogenetic Map15F3UniSTS
cM Map1558.7UniSTS
Krt18  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3813117,457,941 - 117,458,104UniSTSGRCm38
MGSCv3713118,246,748 - 118,246,911UniSTSGRCm37
Celera13121,863,262 - 121,863,425UniSTS
Cytogenetic Map13D2.3UniSTS
Cytogenetic Map15F3UniSTS
cM Map1558.86UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402117102988123Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800000102100000Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578270103517472Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556323312103517472Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564434485103517472Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570461452104043685Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570465070104043685Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570465070104043685Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572498466104043685Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573545941104043685Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577629711104043685Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78716903102993272Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578716903102993272Mouse
14928306Manh79_mmandible shape 79 (mouse)1578949676104043685Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1579000000104043685Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579265530104043685Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined80011059104043685Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580415753104043685Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580987052104043685Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580987052104043685Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82717593104043685Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585988005104043685Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585988005104043685Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585988005104043685Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585993114104043685Mouse
1301764Chab4_mcholesterol absorption 4 (mouse)Not determined1586751919104043685Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92890759103517472Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597800000103100000Mouse
11528547Sluc34_msusceptibility to lung cancer 34 (mouse)1597987052102988123Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:161
Count of miRNA genes:154
Interacting mature miRNAs:161
Transcripts:ENSMUST00000023803
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC139844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW539037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV561123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M22832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M36376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000023803   ⟹   ENSMUSP00000023803
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl15102,028,180 - 102,032,027 (+)Ensembl
RefSeq Acc Id: NM_010664   ⟹   NP_034794
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3915101,936,651 - 101,940,461 (+)NCBI
GRCm3815102,028,216 - 102,032,026 (+)NCBI
MGSCv3715101,858,647 - 101,862,457 (+)RGD
Celera15104,183,109 - 104,186,912 (+)RGD
cM Map15 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034794   ⟸   NM_010664
- UniProtKB: P05784 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000023803   ⟸   ENSMUST00000023803
Protein Domains
IF rod

Promoters
RGD ID:6826131
Promoter ID:MM_KWN:19816
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell,   Liver,   Lung
Transcripts:NM_010664
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3615101,858,436 - 101,858,936 (+)MPROMDB
RGD ID:8685162
Promoter ID:EPDNEW_M20612
Type:initiation region
Name:Krt18_1
Description:Mus musculus keratin 18 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3815102,028,228 - 102,028,288EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96692 AgrOrtholog
Ensembl Genes ENSMUSG00000023043 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000023803 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000023803 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.1160 UniProtKB/Swiss-Prot
InterPro IF_conserved UniProtKB/Swiss-Prot
  IF_rod_dom UniProtKB/Swiss-Prot
  IF_rod_dom_coil1B UniProtKB/Swiss-Prot
  Keratin-18 UniProtKB/Swiss-Prot
  Keratin_I UniProtKB/Swiss-Prot
KEGG Report mmu:16668 UniProtKB/Swiss-Prot
MGD MGI:96692 ENTREZGENE
NCBI Gene 16668 ENTREZGENE
PANTHER PTHR23239 UniProtKB/Swiss-Prot
  PTHR23239:SF349 UniProtKB/Swiss-Prot
Pfam Filament UniProtKB/Swiss-Prot
PhenoGen Krt18 PhenoGen
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot
  IF_ROD_2 UniProtKB/Swiss-Prot
SMART Filament UniProtKB/Swiss-Prot
UniGene Mm.22479 ENTREZGENE
UniProt K1C18_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3TIX1 UniProtKB/Swiss-Prot
  Q3TJH6 UniProtKB/Swiss-Prot
  Q3TJW7 UniProtKB/Swiss-Prot
  Q61766 UniProtKB/Swiss-Prot