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Gene: Pappa2 (pappalysin 2) Mus musculus
Symbol: Pappa2
Name: pappalysin 2
Description: Predicted to have metalloendopeptidase activity. Involved in bone morphogenesis. Predicted to localize to apical plasma membrane and cytosol. Is expressed in several structures, including alimentary system; bone; genitourinary system; nervous system; and retina layer. Orthologous to human PAPPA2 (pappalysin 2); INTERACTS WITH 4,4'-sulfonyldiphenol; Benzo[k]fluoranthene; bisphenol F.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: PAPP-A2; pappalysin-2; Pappe; PLAC3; placenta-specific 3; pregnancy-associated plasma preproprotein-A2; pregnancy-associated plasma protein-E
Homo sapiens (human) : PAPPA2 (pappalysin 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pappa2 (pappalysin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pappa2 (pappalysin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PAPPA2 (pappalysin 2)
Canis lupus familiaris (dog) : PAPPA2 (pappalysin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pappa2 (pappalysin 2)
Sus scrofa (pig) : PAPPA2 (pappalysin 2)
Chlorocebus sabaeus (African green monkey) : PAPPA2 (pappalysin 2)
Heterocephalus glaber (naked mole-rat) : Pappa2 (pappalysin 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1158,711,727 - 158,980,490 (-)EnsemblGRCm38mm10GRCm38
GRCm381158,711,727 - 158,960,451 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371160,641,862 - 160,887,569 (-)NCBIGRCm37mm9NCBIm37
MGSCv361160,548,404 - 160,794,115 (-)NCBImm8
Celera1161,107,178 - 161,348,433 (-)NCBICelera
Cytogenetic Map1H1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pappa2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1620878
Created: 2007-05-01
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.