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Gene: Rnpep (arginyl aminopeptidase (aminopeptidase B)) Mus musculus
Symbol: Rnpep
Name: arginyl aminopeptidase (aminopeptidase B)
Description: Predicted to have metalloaminopeptidase activity; peptide binding activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of blood pressure and proteolysis. Predicted to localize to several cellular components, including the Golgi apparatus; external side of plasma membrane; and secretory granule. Is expressed in central nervous system and sensory organ. Orthologous to human RNPEP (arginyl aminopeptidase); PARTICIPATES IN angiotensin IV signaling pathway; renin-angiotensin cascade pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aminopeptidase B; AP-B; arginine aminopeptidase; cytosol aminopeptidase IV; MGC29229
Homo sapiens (human) : RNPEP (arginyl aminopeptidase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rnpep (arginyl aminopeptidase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnpep (arginyl aminopeptidase)
Pan paniscus (bonobo/pygmy chimpanzee) : RNPEP (arginyl aminopeptidase)
Canis lupus familiaris (dog) : RNPEP (arginyl aminopeptidase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnpep (arginyl aminopeptidase)
Sus scrofa (pig) : RNPEP (arginyl aminopeptidase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381135,262,699 - 135,284,423 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371137,159,276 - 137,180,661 (-)NCBIGRCm37mm9NCBIm37
MGSCv361137,079,123 - 137,100,445 (-)NCBImm8
Celera1137,887,970 - 137,909,160 (-)NCBICelera
Cytogenetic Map1 E4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rnpep
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735492
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.