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Gene: Grk5 (G protein-coupled receptor kinase 5) Mus musculus
Symbol: Grk5
Name: G protein-coupled receptor kinase 5
RGD ID: 62277
Description: Predicted to have beta-adrenergic receptor kinase activity and protein serine/threonine kinase activity. Involved in fat cell differentiation. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human GRK5 (G protein-coupled receptor kinase 5); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; dopamine signaling pathway via D1 family of receptors; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: g protein-coupled receptor kinase GRK5; Gpr; Gprk5
Homo sapiens (human) : GRK5 (G protein-coupled receptor kinase 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grk5 (G protein-coupled receptor kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grk5 (G protein-coupled receptor kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GRK5 (G protein-coupled receptor kinase 5)
Canis lupus familiaris (dog) : GRK5 (G protein-coupled receptor kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grk5 (G protein-coupled receptor kinase 5)
Sus scrofa (pig) : GRK5 (G protein-coupled receptor kinase 5)
Chlorocebus sabaeus (African green monkey) : GRK5 (G protein-coupled receptor kinase 5)
Heterocephalus glaber (naked mole-rat) : Grk5 (G protein-coupled receptor kinase 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1960,889,749 - 61,095,968 (+)EnsemblGRCm38mm10GRCm38
GRCm381960,889,560 - 61,095,968 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371960,965,652 - 61,168,459 (+)NCBIGRCm37mm9NCBIm37
MGSCv361960,945,139 - 61,147,005 (+)NCBImm8
Celera1963,189,741 - 63,294,504 (+)NCBICelera
Cytogenetic Map19D3NCBI
cM Map1956.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Grk5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62277
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.