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Gene: Grk5 (G protein-coupled receptor kinase 5) Mus musculus
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Symbol: Grk5
Name: G protein-coupled receptor kinase 5
RGD ID: 62277
Description: Predicted to have beta-adrenergic receptor kinase activity and protein serine/threonine kinase activity. Involved in fat cell differentiation. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human GRK5 (G protein-coupled receptor kinase 5); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptor; angiotensin II signaling pathway via AT1 receptor; dopamine signaling pathway via D1 family of receptors; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: g protein-coupled receptor kinase GRK5; Gpr; Gprk5
Orthologs:
Homo sapiens (human) : GRK5 (G protein-coupled receptor kinase 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Grk5 (G protein-coupled receptor kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Grk5 (G protein-coupled receptor kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : GRK5 (G protein-coupled receptor kinase 5)
Canis lupus familiaris (dog) : GRK5 (G protein-coupled receptor kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Grk5 (G protein-coupled receptor kinase 5)
Sus scrofa (pig) : GRK5 (G protein-coupled receptor kinase 5)
Chlorocebus sabaeus (African green monkey) : GRK5 (G protein-coupled receptor kinase 5)
Heterocephalus glaber (naked mole-rat) : Grk5 (G protein-coupled receptor kinase 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1960,889,749 - 61,095,968 (+)EnsemblGRCm38mm10GRCm38
GRCm381960,889,560 - 61,095,968 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371960,965,652 - 61,168,459 (+)NCBIGRCm37mm9NCBIm37
MGSCv361960,945,139 - 61,147,005 (+)NCBImm8
Celera1963,189,741 - 63,294,504 (+)NCBICelera
Cytogenetic Map19D3NCBI
cM Map1956.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Grk5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62277
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.