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Gene: Rela (v-rel reticuloendotheliosis viral oncogene homolog A (avian)) Mus musculus
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Symbol: Rela
Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Description: Exhibits several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and ankyrin repeat binding activity. Involved in several processes, including animal organ development; negative regulation of protein metabolic process; and regulation of macromolecule biosynthetic process. Localizes to the cytosol; glutamatergic synapse; and nuclear chromatin. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Is expressed in several structures, including alimentary system; genitourinary system; musculature; respiratory system; and skin. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit); PARTICIPATES IN ceramide signaling pathway; interleukin-1 signaling pathway; interleukin-12 signaling pathway; INTERACTS WITH (+)-catechin; (-)-hinokiresinol; (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: avian reticuloendotheliosis viral (v-rel) oncogene homolog A; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; p65 NF kappaB; p65 NF-kappa B; p65 NFkB; transcription factor p65
Orthologs:
Homo sapiens (human) : RELA (RELA proto-oncogene, NF-kB subunit)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rela (RELA proto-oncogene, NF-kB subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rela (RELA proto-oncogene, NF-kB subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : RELA (RELA proto-oncogene, NF-kB subunit)
Canis lupus familiaris (dog) : RELA (RELA proto-oncogene, NF-kB subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rela (RELA proto-oncogene, NF-kB subunit)
Sus scrofa (pig) : RELA (RELA proto-oncogene, NF-kB subunit)
Chlorocebus sabaeus (African green monkey) : RELA (RELA proto-oncogene, NF-kB subunit)
Heterocephalus glaber (naked mole-rat) : Rela (RELA proto-oncogene, NF-kB subunit)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl195,637,483 - 5,648,130 (+)Ensembl
GRCm38195,637,442 - 5,648,134 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37195,637,490 - 5,648,130 (+)NCBIGRCm37mm9NCBIm37
MGSCv36195,637,490 - 5,648,130 (+)NCBImm8
Celera195,507,082 - 5,517,707 (+)NCBICelera
Cytogenetic Map19 ANCBI
cM Map194.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model