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Gene: Apoa4 (apolipoprotein A-IV) Mus musculus
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Symbol: Apoa4
Name: apolipoprotein A-IV
Description: Predicted to have several functions, including cation binding activity; cholesterol binding activity; and cholesterol transfer activity. Involved in innate immune response in mucosa; regulation of intestinal cholesterol absorption; and response to stilbenoid. Localizes to the extracellular space. Predicted to colocalize with the cell surface. Human ortholog(s) of this gene implicated in Alzheimer's disease; colitis; myocardial infarction; and ulcerative colitis. Is expressed in embryo and liver. Orthologous to human APOA4 (apolipoprotein A4); PARTICIPATES IN altered lipoprotein metabolic pathway; lipoprotein metabolic pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,2-dichloroethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apo-AIV; Apoa-4; apoA-IV; apolipoprotein A4
Orthologs:
Homo sapiens (human) : APOA4 (apolipoprotein A4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apoa4 (apolipoprotein A4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apoa4 (apolipoprotein A4)
Pan paniscus (bonobo/pygmy chimpanzee) : APOA4 (apolipoprotein A4)
Canis lupus familiaris (dog) : APOA4 (apolipoprotein A4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apoa4 (apolipoprotein A4)
Sus scrofa (pig) : APOA4 (apolipoprotein A4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38946,240,844 - 46,243,458 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37946,048,927 - 46,051,541 (+)NCBIGRCm37mm9NCBIm37
MGSCv36945,992,149 - 45,994,285 (+)NCBImm8
Celera943,529,774 - 43,532,388 (+)NCBICelera
Cytogenetic Map9 A5.2NCBI
cM Map925.36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Apoa4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734420
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.