Ccl4 (chemokine (C-C motif) ligand 4) - Rat Genome Database

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Gene: Ccl4 (chemokine (C-C motif) ligand 4) Mus musculus
Analyze
Symbol: Ccl4
Name: chemokine (C-C motif) ligand 4
RGD ID: 1550761
MGI Page MGI
Description: Predicted to enable chemokine receptor binding activity and identical protein binding activity. Acts upstream of or within cellular response to drug. Located in extracellular space. Is expressed in central nervous system; genitourinary system; and retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and human immunodeficiency virus infectious disease. Orthologous to several human genes including CCL4L2 (C-C motif chemokine ligand 4 like 2); PARTICIPATES IN interleukin-12 signaling pathway; Toll-like receptor signaling pathway; INTERACTS WITH (+)-catechin; (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid; 1-chloro-2,4-dinitrobenzene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Act-; Act-2; ACT2; AT744.; AT744.1; C-C motif chemokine 4; immune activation protein 2; macrophage inflammatory protein 1-beta; Mip; MIP-; MIP-1 beta; MIP-1-beta; MIP-1B; Mip1b; Scy; Scya4; SIS-gamma; small inducible cytokine A4; small-inducible cytokine A4
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,553,410 - 83,555,509 (+)NCBIGRCm39mm39
GRCm39 Ensembl1183,553,410 - 83,555,509 (+)Ensembl
GRCm381183,648,624 - 83,664,683 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,662,584 - 83,664,683 (+)EnsemblGRCm38mm10GRCm38
MGSCv371183,476,086 - 83,478,185 (+)NCBIGRCm37mm9NCBIm37
MGSCv361183,478,782 - 83,480,875 (+)NCBImm8
Celera1193,266,966 - 93,269,065 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (ISO)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (EXP)
(R)-mevalonic acid  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,4-benzoquinone  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP,ISO)
1-fluoro-2,4-dinitrobenzene  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
15-acetyldeoxynivalenol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-D  (EXP)
2,6-dichloroindophenol  (ISO)
2-hydroxypropanoic acid  (ISO)
26-hydroxycholesterol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-phenylprop-2-enal  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nitroquinoline N-oxide  (EXP)
7-ketocholesterol  (ISO)
7alpha-hydroxycholesterol  (ISO)
acetamide  (ISO)
acrylamide  (EXP)
alclometasone dipropionate  (ISO)
alexidine  (ISO)
all-trans-retinoic acid  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
aluminium hydroxide  (ISO)
ammonium chloride  (ISO)
amphibole asbestos  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aripiprazole  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
asperentin  (EXP)
Bandrowski's base  (ISO)
Bardoxolone methyl  (EXP)
barium sulfate  (ISO)
beclomethasone  (ISO)
benzalkonium chloride  (EXP,ISO)
benzene  (EXP)
benzene-1,2,4-triol  (ISO)
benzethonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzocaine  (ISO)
beryllium sulfate  (ISO)
betamethasone  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (ISO)
bleomycin A2  (EXP)
budesonide  (ISO)
C.I. Natural Red 20  (EXP)
Calcimycin  (EXP)
camptothecin  (ISO)
carbon nanotube  (EXP,ISO)
catechol  (ISO)
cefaloridine  (ISO)
cephaeline  (ISO)
ceric oxide  (ISO)
chloromethylisothiazolinone  (ISO)
chlorothalonil  (ISO)
chlorpyrifos  (EXP)
cholesterol  (ISO)
choline  (EXP)
chrysene  (EXP)
cis-caffeic acid  (EXP)
cisplatin  (ISO)
clopidogrel  (ISO)
cobalt atom  (ISO)
cobalt(2+) sulfate  (ISO)
cortisol  (ISO)
crocidolite asbestos  (EXP)
Cuprizon  (ISO)
cyclosporin A  (ISO)
D-penicillamine  (ISO)
daunorubicin  (ISO)
Decursin  (EXP)
deoxynivalenol  (EXP,ISO)
dequalinium  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dichromium trioxide  (ISO)
digitoxigenin  (ISO)
digoxigenin  (ISO)
digoxin  (ISO)
dihydroxyacetone  (ISO)
dimethyl-(phenylmethyl)-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]ammonium  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (ISO)
emetine  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
farnesol  (ISO)
ferric oxide  (EXP,ISO)
fludrocortisone  (ISO)
flumequine  (EXP)
folic acid  (EXP)
fumonisin B1  (ISO)
furan  (EXP,ISO)
gadodiamide hydrate  (ISO)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glutaraldehyde  (ISO)
graphene oxide  (EXP)
graphite  (ISO)
hydralazine  (ISO)
hydrogen chloride  (ISO)
hydroquinone  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
L-methionine  (EXP)
lanatoside C  (ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
linuron  (EXP)
lipopolysaccharide  (EXP,ISO)
meclocycline  (ISO)
MeIQx  (EXP)
metam  (EXP)
methamphetamine  (ISO)
methionine sulfoximine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (EXP)
minocycline  (ISO)
mycophenolic acid  (EXP)
mycotoxin  (EXP)
N-methyl-N-nitrosourea  (ISO)
neocuproine  (EXP)
neoechinulin A  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (ISO)
oxytetracycline  (ISO)
ozone  (EXP,ISO)
palmatine  (ISO)
paracetamol  (EXP)
perfluorooctanoic acid  (EXP)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phthalic anhydride  (EXP)
poly(I:C)  (EXP,ISO)
potassium dichromate  (EXP,ISO)
prednisolone  (ISO)
propidium  (ISO)
Proscillaridin  (ISO)
prostaglandin E2  (EXP,ISO)
puromycin  (ISO)
pyrrolidine dithiocarbamate  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
ritonavir  (ISO)
roflumilast  (ISO)
SB 203580  (ISO)
serpentine asbestos  (EXP,ISO)
Shikonin  (EXP)
silicon dioxide  (EXP,ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (ISO)
Soman  (ISO)
succimer  (EXP,ISO)
sunitinib  (EXP)
tamibarotene  (ISO)
taurocholic acid  (EXP)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thiostrepton  (ISO)
tigecycline  (ISO)
titanium dioxide  (EXP,ISO)
toluene 2,4-diisocyanate  (EXP)
topotecan  (ISO)
trans-caffeic acid  (EXP)
tremolite asbestos  (EXP)
Tributyltin oxide  (EXP)
trimellitic anhydride  (EXP)
trimethyltin  (EXP)
triptonide  (EXP)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
usnic acid  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
Y-27632  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Arankalle VA, etal., PLoS One. 2010 Oct 1;5(10). pii: e13099.
2. Barczyk A, etal., Pneumonol Alergol Pol. 2001;69(1-2):40-9.
3. Bellastella G, etal., J Endocrinol Invest. 2010 Dec 15.
4. Bless NM, etal., J Immunol 2000 Mar 1;164(5):2650-9.
5. Brennan S, etal., Eur Respir J. 2009 Sep;34(3):655-61. Epub 2009 Apr 22.
6. Codullo V, etal., Ann Rheum Dis. 2011 Jun;70(6):1115-21. Epub 2011 Feb 1.
7. Farquhar C, etal., Curr HIV Res. 2005 Oct;3(4):361-9.
8. Fraser DD, etal., Crit Care Explor. 2020 Jun 22;2(6):e0144. doi: 10.1097/CCE.0000000000000144. eCollection 2020 Jun.
9. Garcia GE, etal., FASEB J. 2008 Feb;22(2):445-54. Epub 2007 Sep 26.
10. Goleva E, etal., J Allergy Clin Immunol. 2008 Sep;122(3):550-9.e3.
11. Guzik-Kornacka A, etal., Acta Neurobiol Exp (Wars). 2011;71(2):193-207.
12. Hekiert AM, etal., Otolaryngol Head Neck Surg. 2009 Oct;141(4):448-53.
13. Huang C, etal., Lancet. 2020 Feb 15;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24.
14. Kishi J, etal., Eur Respir J. 2011 Aug;38(2):415-24. Epub 2011 Jan 27.
15. Lee JS, etal., Respir Res. 2007 Sep 14;8:64.
16. Leifeld L, etal., J Pathol. 2003 Mar;199(3):335-44. doi: 10.1002/path.1298.
17. Lin FC, etal., Mayo Clin Proc. 2008 Dec;83(12):1344-9.
18. Liu J, etal., J Immunoassay Immunochem. 2010 Oct;31(4):279-89.
19. Maijo M, etal., Br J Nutr. 2011 Sep 12:1-9.
20. Mera S, etal., APMIS. 2011 Feb;119(2):155-63. doi: 10.1111/j.1600-0463.2010.02705.x. Epub 2010 Dec 10.
21. Meuronen A, etal., Respiration. 2008;75(4):450-8. Epub 2008 Jan 30.
22. MGD data from the GO Consortium
23. Mittal N and Sanyal SN, J Immunotoxicol. 2011 Oct-Dec;8(4):274-83. Epub 2011 Jul 18.
24. Modi WS, etal., Am J Hum Genet. 2006 Jul;79(1):120-8. Epub 2006 May 30.
25. Mrugacz M J Interferon Cytokine Res. 2010 Jul;30(7):509-12.
26. Ochiel DO, etal., Infect Immun. 2005 Jul;73(7):4190-7.
27. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
28. Pattarini R, etal., Neuroscience. 2007 Mar 16;145(2):654-68. Epub 2007 Jan 29.
29. Pipeline to import KEGG annotations from KEGG into RGD
30. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
31. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
32. RGD automated import pipeline for gene-chemical interactions
33. Rodriguez N, etal., J Leukoc Biol. 2010 Sep;88(3):579-87. Epub 2010 May 18.
34. Schutz C, etal., PLoS Med. 2019 Jul 5;16(7):e1002840. doi: 10.1371/journal.pmed.1002840. eCollection 2019 Jul.
35. Shankar K, etal., Endocrinology. 2011 Nov;152(11):4158-70. Epub 2011 Aug 23.
36. Shin JJ, etal., Arthritis Rheum. 2007 Apr;56(4):1325-35.
37. Sisay Z, etal., Ethiop Med J. 2011 Jul;49(3):179-86.
38. Sun X, etal., Infect Immun. 2006 Oct;74(10):5943-54.
39. Szodoray P, etal., Rheumatology (Oxford). 2007 Mar;46(3):417-25. Epub 2006 Aug 27.
40. Tripathy AS, etal., J Viral Hepat. 2011 Oct;18(10):e415-22. doi: 10.1111/j.1365-2893.2011.01457.x. Epub 2011 May 18.
41. Vila LM, etal., Clin Rheumatol. 2007 May;26(5):718-22. Epub 2006 Aug 19.
42. Yang Y, etal., J Allergy Clin Immunol. 2020 Apr 29. pii: S0091-6749(20)30576-5. doi: 10.1016/j.jaci.2020.04.027.
43. Yuan TM, etal., J Perinat Med. 2005;33(5):415-22.
Additional References at PubMed
PMID:1969921   PMID:1972563   PMID:2521353   PMID:3058856   PMID:7594543   PMID:7594550   PMID:7601457   PMID:7789623   PMID:7835696   PMID:8496601   PMID:8530103   PMID:9139699  
PMID:9177770   PMID:9311871   PMID:9510207   PMID:10235110   PMID:10349636   PMID:10438970   PMID:10594742   PMID:10995569   PMID:11042159   PMID:11069716   PMID:11076861   PMID:11217851  
PMID:11756344   PMID:11972057   PMID:12050188   PMID:12080938   PMID:12126650   PMID:12377948   PMID:12393512   PMID:12393595   PMID:12401480   PMID:12477932   PMID:12960284   PMID:14761932  
PMID:15381731   PMID:15498767   PMID:15611273   PMID:15630139   PMID:15897346   PMID:15967376   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16637021   PMID:16982098   PMID:17327452  
PMID:17525185   PMID:18287559   PMID:18566004   PMID:19853894   PMID:20046229   PMID:20691261   PMID:21267068   PMID:21677750   PMID:21873635   PMID:21912378   PMID:22528550   PMID:22538808  
PMID:22960654   PMID:23007134   PMID:23112334   PMID:23431040   PMID:23648818   PMID:23878190   PMID:24244314   PMID:24339898   PMID:24370436   PMID:24486487   PMID:25595646   PMID:25847238  
PMID:25895671   PMID:26786659   PMID:27022143   PMID:27177471   PMID:27318131   PMID:27879269   PMID:28092793   PMID:28096401   PMID:29739756   PMID:29987448   PMID:30471926   PMID:30854716  
PMID:33046212   PMID:33887203   PMID:33968046  


Genomics

Comparative Map Data
Ccl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391183,553,410 - 83,555,509 (+)NCBIGRCm39mm39
GRCm39 Ensembl1183,553,410 - 83,555,509 (+)Ensembl
GRCm381183,648,624 - 83,664,683 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1183,662,584 - 83,664,683 (+)EnsemblGRCm38mm10GRCm38
MGSCv371183,476,086 - 83,478,185 (+)NCBIGRCm37mm9NCBIm37
MGSCv361183,478,782 - 83,480,875 (+)NCBImm8
Celera1193,266,966 - 93,269,065 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1151.09NCBI
CCL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1736,103,827 - 36,105,621 (+)EnsemblGRCh38hg38GRCh38
GRCh381736,103,827 - 36,105,614 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371734,431,220 - 34,433,007 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361731,455,333 - 31,457,127 (+)NCBINCBI36hg18NCBI36
Build 341731,455,332 - 31,457,127NCBI
Celera1731,340,772 - 31,342,566 (+)NCBI
Cytogenetic Map17q12NCBI
HuRef1730,615,959 - 30,617,753 (+)NCBIHuRef
CHM1_11734,495,398 - 34,497,192 (+)NCBICHM1_1
Ccl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21068,466,469 - 68,467,941 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1068,452,052 - 68,468,231 (+)Ensembl
Rnor_6.01070,870,926 - 70,886,357 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,884,531 - 70,886,355 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01070,502,606 - 70,518,350 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,759,643 - 71,761,115 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,774,012 - 71,775,485 (+)NCBI
Celera1067,405,932 - 67,407,404 (+)NCBICelera
Cytogenetic Map10q26NCBI
CCL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1937,681,342 - 37,682,691 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl937,676,966 - 37,710,209 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha936,905,070 - 36,906,419 (-)NCBI
ROS_Cfam_1.0938,491,608 - 38,492,957 (-)NCBI
UMICH_Zoey_3.1937,273,230 - 37,274,579 (-)NCBI
UNSW_CanFamBas_1.0937,560,499 - 37,561,848 (-)NCBI
UU_Cfam_GSD_1.0937,647,662 - 37,649,011 (-)NCBI
CCL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1239,478,885 - 39,557,358 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11239,479,190 - 39,480,511 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,048,660 - 41,049,981 (-)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
M23503  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,664,403 - 83,664,498UniSTSGRCm38
MGSCv371183,477,905 - 83,478,000UniSTSGRCm37
Celera1193,268,785 - 93,268,880UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.6UniSTS
Whitehead/MRC_RH111065.91UniSTS
PMC98533P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381183,664,312 - 83,664,453UniSTSGRCm38
MGSCv371183,477,814 - 83,477,955UniSTSGRCm37
Celera1193,268,694 - 93,268,835UniSTS
Cytogenetic Map11CUniSTS
cM Map1147.6UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179265183107725646Mouse
14746970Manh71_mmandible shape 71 (mouse)1179525431113525431Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179922933104611872Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1181000000102000000Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181683655115683810Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181683655115683810Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181919441115919441Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182486872116486994Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:150
Interacting mature miRNAs:152
Transcripts:ENSMUST00000019074
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_013652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF128218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF128219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK172472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596122 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC119257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC119259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY157376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY163868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M23503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S61348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X62502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000019074   ⟹   ENSMUSP00000019074
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1183,553,410 - 83,555,509 (+)Ensembl
GRCm38.p6 Ensembl1183,662,584 - 83,664,683 (+)Ensembl
RefSeq Acc Id: NM_013652   ⟹   NP_038680
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391183,553,410 - 83,555,509 (+)NCBI
GRCm381183,662,584 - 83,664,683 (+)NCBI
MGSCv371183,476,086 - 83,478,185 (+)RGD
Celera1193,266,966 - 93,269,065 (+)RGD
cM Map11 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_038680   ⟸   NM_013652
- Peptide Label: precursor
- UniProtKB: P14097 (UniProtKB/Swiss-Prot),   Q5QNV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000019074   ⟸   ENSMUST00000019074
Protein Domains
SCY

Promoters
RGD ID:6820570
Promoter ID:MM_KWN:8908
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:NM_013652
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361183,475,959 - 83,476,459 (+)MPROMDB
RGD ID:8675920
Promoter ID:EPDNEW_M15991
Type:multiple initiation site
Name:Ccl4_1
Description:Mus musculus chemokine (C-C motif) ligand 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381183,662,587 - 83,662,647EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98261 AgrOrtholog
Ensembl Genes ENSMUSG00000018930 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000019074 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000019074 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Chemokine_b/g/d UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_CC_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Chemokine_IL8-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Interleukin_8-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20303 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98261 ENTREZGENE
NCBI Gene 20303 ENTREZGENE
PANTHER PTHR12015 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam IL8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccl4 PhenoGen
PROSITE SMALL_CYTOKINES_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SCY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CCL4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q5QNV9 ENTREZGENE, UniProtKB/TrEMBL