Bhlhe41 (basic helix-loop-helix family, member e41) - Rat Genome Database

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Gene: Bhlhe41 (basic helix-loop-helix family, member e41) Mus musculus
Analyze
Symbol: Bhlhe41
Name: basic helix-loop-helix family, member e41
RGD ID: 731062
MGI Page MGI
Description: Enables several functions, including DNA-binding transcription factor binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and protein dimerization activity. Involved in circadian regulation of gene expression; negative regulation of DNA-templated transcription; and negative regulation of myotube differentiation. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; heart; sensory organ; and testis. Orthologous to human BHLHE41 (basic helix-loop-helix family member e41).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 6430520M22Rik; basic helix-loop-helix domain containing, class B, 2-like; basic helix-loop-helix domain containing, class B3; bHLH transcriptional factor Dec2; Bhlhb; Bhlhb2l; Bhlhb3; class B basic helix-loop-helix protein 3; class E basic helix-loop-helix protein 41; DEC2; differentially expressed in chondrocytes protein 2; mDEC2; RIKEN cDNA 6430520M22 gene; Sh; Sharp1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,803,969 - 145,811,146 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,803,969 - 145,811,284 (-)EnsemblGRCm39 Ensembl
GRCm386145,858,243 - 145,865,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,858,243 - 145,865,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv376145,811,257 - 145,813,860 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366145,819,896 - 145,822,499 (-)NCBIMGSCv36mm8
Celera6148,934,952 - 148,937,555 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,3-dinitrobenzene  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxynon-2-enal  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiolic acid  (ISO)
cantharidin  (EXP)
carbon nanotube  (EXP)
cefaloridine  (ISO)
chloroprene  (ISO)
choline  (EXP)
cisplatin  (ISO)
clofibric acid  (ISO)
crocidolite asbestos  (ISO)
dexamethasone  (ISO)
dichloroacetic acid  (EXP)
diethyl maleate  (ISO)
dimethylarsinic acid  (EXP)
dimethylarsinous acid  (ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (ISO)
fenamidone  (EXP)
folic acid  (EXP,ISO)
FR900359  (ISO)
genistein  (EXP)
gentamycin  (ISO)
ketamine  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (EXP,ISO)
methylarsonic acid  (EXP)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium dichromate  (EXP)
progesterone  (ISO)
propanal  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
sunitinib  (ISO)
Tesaglitazar  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
topotecan  (ISO)
tributylstannane  (EXP)
trichloroethene  (EXP,ISO)
troglitazone  (ISO)
undecane  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. BHLHB3: a candidate tumor suppressor in lung cancer. Falvella FS, etal., Oncogene. 2008 Jun 12;27(26):3761-4. doi: 10.1038/sj.onc.1211038. Epub 2008 Jan 28.
2. Dec1 and Dec2 are regulators of the mammalian molecular clock. Honma S, etal., Nature 2002 Oct 24;419(6909):841-4.
3. MicroRNA-873 acts as a tumor suppressor in esophageal cancer by inhibiting differentiated embryonic chondrocyte expressed gene 2. Liang Y, etal., Biomed Pharmacother. 2018 Sep;105:582-589. doi: 10.1016/j.biopha.2018.05.152. Epub 2018 Jun 8.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. The clock gene PER1 plays an important role in regulating the clock gene network in human oral squamous cell carcinoma cells. Zhao Q, etal., Oncotarget. 2016 Oct 25;7(43):70290-70302. doi: 10.18632/oncotarget.11844.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10610183   PMID:11042159   PMID:11076861   PMID:11162494   PMID:11217851   PMID:12175508   PMID:12466851   PMID:12477932   PMID:12657651   PMID:14672706  
PMID:15038852   PMID:15147242   PMID:15448136   PMID:15560782   PMID:15618518   PMID:15970569   PMID:16141072   PMID:16141073   PMID:16267380   PMID:16602821   PMID:16685415   PMID:16873396  
PMID:17453843   PMID:17487425   PMID:18233956   PMID:18287559   PMID:18342625   PMID:18411297   PMID:18648504   PMID:19029947   PMID:19679812   PMID:19786558   PMID:19880450   PMID:19881507  
PMID:20006609   PMID:21267068   PMID:21873635   PMID:21893041   PMID:22080784   PMID:22215611   PMID:22244086   PMID:22801492   PMID:23087213   PMID:23223373   PMID:24357723   PMID:24736997  
PMID:24942744   PMID:24952961   PMID:25340473   PMID:25446074   PMID:26100875   PMID:27284410   PMID:28250425   PMID:29472596   PMID:29692408   PMID:29926321   PMID:30555544   PMID:30988352  
PMID:31414712   PMID:32527940   PMID:32795896   PMID:33437170   PMID:34584158   PMID:34919144   PMID:35172136   PMID:35187871   PMID:35989621   PMID:36189231   PMID:37511489  


Genomics

Comparative Map Data
Bhlhe41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,803,969 - 145,811,146 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6145,803,969 - 145,811,284 (-)EnsemblGRCm39 Ensembl
GRCm386145,858,243 - 145,865,420 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,858,243 - 145,865,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv376145,811,257 - 145,813,860 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366145,819,896 - 145,822,499 (-)NCBIMGSCv36mm8
Celera6148,934,952 - 148,937,555 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.7NCBI
BHLHE41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381226,120,030 - 26,125,037 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1226,120,030 - 26,125,037 (-)EnsemblGRCh38hg38GRCh38
GRCh371226,272,963 - 26,277,970 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,164,226 - 26,169,113 (-)NCBINCBI36Build 36hg18NCBI36
Build 341226,164,227 - 26,169,113NCBI
Celera1231,419,506 - 31,424,550 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1226,043,295 - 26,047,960 (-)NCBIHuRef
CHM1_11226,237,976 - 26,243,020 (-)NCBICHM1_1
T2T-CHM13v2.01225,992,585 - 25,998,690 (-)NCBIT2T-CHM13v2.0
Bhlhe41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84180,565,003 - 180,569,415 (-)NCBIGRCr8
mRatBN7.24178,834,264 - 178,838,618 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4178,834,271 - 178,838,468 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4185,117,084 - 185,121,450 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04180,901,598 - 180,905,964 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04179,522,031 - 179,526,399 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04180,230,742 - 180,235,138 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4180,232,382 - 180,234,804 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04244,394,139 - 244,398,535 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4167,334,944 - 167,338,512 (-)NCBICelera
Cytogenetic Map4q44NCBI
Bhlhe41
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541321,100,021 - 21,103,358 (-)NCBIChiLan1.0ChiLan1.0
BHLHE41
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21070,697,481 - 70,702,552 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11270,693,542 - 70,698,949 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01260,194,758 - 60,199,344 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11262,806,113 - 62,810,773 (+)NCBIpanpan1.1PanPan1.1panPan2
BHLHE41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12721,464,302 - 21,469,119 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2724,913,768 - 24,918,529 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02721,659,233 - 21,663,998 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2721,659,186 - 21,663,998 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12721,469,068 - 21,473,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02721,491,838 - 21,496,575 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02725,081,155 - 25,085,938 (-)NCBIUU_Cfam_GSD_1.0
Bhlhe41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494583,384,039 - 83,391,789 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365481,306,939 - 1,314,678 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BHLHE41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl547,686,404 - 47,692,762 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1547,687,662 - 47,692,761 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2551,429,074 - 51,433,848 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BHLHE41
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11125,872,139 - 25,879,985 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1125,874,108 - 25,876,826 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660699,196,174 - 9,200,076 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bhlhe41
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475213,000,525 - 13,003,079 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475213,000,238 - 13,004,777 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Bhlhe41
319 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1549
Count of miRNA genes:773
Interacting mature miRNAs:975
Transcripts:ENSMUST00000032386, ENSMUST00000111703
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301027Hdlq12_mHDL QTL 12 (mouse)Not determined6128601582149588044Mouse
1301084Bpq5_mblood pressure QTL 5 (mouse)Not determined6129330484149588044Mouse
1301152Athsq2_matherosclerosis susceptibility QTL 2 (mouse)Not determined6117059949149588044Mouse
1301620Insq8_minsulin QTL 8 (mouse)Not determined6129534979149588044Mouse
1301658Radpf3_mradiation pulmonary fibrosis 3 (mouse)Not determined6115219814146330736Mouse
1301686Trmq1_mT cell ratio modifier QTL 1 (mouse)Not determined6129330484149588044Mouse
1301820Mop1_mmorphine preference 1 (mouse)Not determined6132578005146330736Mouse
1301518Bbaa5_mB.burgdorferi-associated arthritis 5 (mouse)Not determined698483798145881170Mouse
1302089Wta2_mweight adult 2 (mouse)Not determined6125269523149588044Mouse
1301804Bulb2_mbulb size 2 (mouse)Not determined6120416806149588044Mouse
1301927Etohcta6_methanol conditioned taste aversion 6 (mouse)Not determined6115578005149578150Mouse
1357555Tesq2_mtestis weight QTL 2 (mouse)Not determined696632912146535124Mouse
1558959Eamcd2_mexperimental autoimmune myocarditis 2 (mouse)Not determined6129953954149588044Mouse
4141194Cyx_mcycloheximide tasting (mouse)Not determined115546805149549364Mouse
4141536Idd6.2_minsulin dependent diabetes susceptibility 6.2 (mouse)Not determined6143556651146215056Mouse
4141295Rua_mraffinose acetate tasting (mouse)Not determined115546805149549364Mouse
4141889Qui_mquinine sensitivity, taste (mouse)Not determined115546805149549364Mouse
4141940W6q5_mweight 6 weeks QTL 5 (mouse)Not determined96632912146535124Mouse
4141974Skmw14_mskeletal muscle weight 14 (mouse)Not determined6129330484149588044Mouse
4142079Skmw15_mskeletal muscle weight 15 (mouse)Not determined6116829851149588044Mouse
4142416Egq11_mearly growth QTL 11 (mouse)Not determined96632912146535124Mouse
11252138Clas1_mcarcinogen-induced lung adenoma susceptibility 1 (mouse)6112246918146954059Mouse
11353842Bmiq4_mbody mass index QTL 4 (mouse)692584287146330736Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683690851146954059Mouse
10053680Lith25_mlithogenic gene 25 (mouse)Not determined6128601582149588044Mouse
10449437Pas15_mpulmonary adenoma susceptibility 15 (mouse)6128180868149588044Mouse
10766452Sle23_msystematic lupus erythematosus susceptibility 23 (mouse)6128601582149588044Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
14746990Manh61_mmandible shape 61 (mouse)6130156355149588044Mouse
14746999Mancz6_mmandible centroid size 6 (mouse)6130156355149588044Mouse
15092045Wngrme2_mweek nine growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092047Wsigrme2_mweek six growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092052Wsegrme2_mweek seven growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092053Wegrme2_mweek eight growth rate, maternal effect 2 (mouse)6140445726147201498Mouse
15092056Mgrme1_mmid growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
15092058Lgrme2_mlate growth rate, maternal effect 2 (mouse)6140497205147252976Mouse
15092060Wfogrme1_mweek four growth rate, maternal effect 1 (mouse)6140497205147252976Mouse
15092061Wfigrme1_mweek five growth rate, maternal effect 1 (mouse)6140445726147201498Mouse

Markers in Region
AI170756  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386145,861,442 - 145,861,646UniSTSGRCm38
MGSCv376145,809,962 - 145,810,166UniSTSGRCm37
Celera6148,933,661 - 148,933,865UniSTS
Cytogenetic Map6G2-G3UniSTS
Bhlhe41  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6G2-G3UniSTS
cM Map677.7UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_024469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA013582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB044090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB126167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC144936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK040945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV341352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC023231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE980915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE985179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000032386   ⟹   ENSMUSP00000032386
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,803,969 - 145,811,284 (-)Ensembl
GRCm38.p6 Ensembl6145,858,243 - 145,865,558 (-)Ensembl
RefSeq Acc Id: ENSMUST00000111703   ⟹   ENSMUSP00000107332
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,809,231 - 145,811,028 (-)Ensembl
GRCm38.p6 Ensembl6145,863,505 - 145,865,302 (-)Ensembl
RefSeq Acc Id: ENSMUST00000203949
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl6145,810,389 - 145,811,078 (-)Ensembl
GRCm38.p6 Ensembl6145,864,663 - 145,865,352 (-)Ensembl
RefSeq Acc Id: NM_001271768   ⟹   NP_001258697
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,803,969 - 145,811,146 (-)NCBI
GRCm386145,858,243 - 145,865,420 (-)NCBI
Celera6148,930,462 - 148,937,635 (-)NCBI
Sequence:
RefSeq Acc Id: NM_024469   ⟹   NP_077789
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm396145,803,969 - 145,811,146 (-)NCBI
GRCm386145,858,243 - 145,865,420 (-)NCBI
MGSCv376145,811,257 - 145,813,860 (-)RGD
Celera6148,930,462 - 148,937,635 (-)NCBI
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_077789   ⟸   NM_024469
- Peptide Label: isoform 1
- UniProtKB: Q99PV5 (UniProtKB/Swiss-Prot),   Q6L8F5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258697   ⟸   NM_001271768
- Peptide Label: isoform 2
- UniProtKB: D3Z2G6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000107332   ⟸   ENSMUST00000111703
RefSeq Acc Id: ENSMUSP00000032386   ⟸   ENSMUST00000032386
Protein Domains
bHLH   Orange

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99PV5-F1-model_v2 AlphaFold Q99PV5 1-410 view protein structure

Promoters
RGD ID:6838767
Promoter ID:MM_KWN:48223
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Lung
Transcripts:AK032333_6430520M22RIK
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366145,807,046 - 145,810,847 (-)MPROMDB
RGD ID:6838989
Promoter ID:MM_KWN:48224
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000111703,   OTTMUST00000062685
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv366145,813,796 - 145,815,072 (-)MPROMDB
RGD ID:6891514
Promoter ID:EPDNEW_M9206
Type:initiation region
Name:Bhlhe41_1
Description:Mus musculus basic helix-loop-helix family, member e41 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm386145,865,402 - 145,865,462EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1930704 AgrOrtholog
Ensembl Genes ENSMUSG00000030256 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000032386 ENTREZGENE
  ENSMUST00000032386.11 UniProtKB/Swiss-Prot
  ENSMUST00000111703 ENTREZGENE
  ENSMUST00000111703.2 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.250.980 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Orange_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:79362 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1930704 ENTREZGENE
NCBI Gene 79362 ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 41 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Hairy_orange UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bhlhe41 PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ORANGE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ORANGE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Orange domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt BHE41_MOUSE UniProtKB/Swiss-Prot
  D3Z2G6 ENTREZGENE, UniProtKB/TrEMBL
  Q6L8F5 ENTREZGENE, UniProtKB/TrEMBL
  Q8CGH4_MOUSE UniProtKB/TrEMBL
  Q99PV5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 Bhlhe41  basic helix-loop-helix family, member e41  6430520M22Rik  RIKEN cDNA 6430520M22 gene  Data merged from RGD:1607157 737654 PROVISIONAL