Igf2r (insulin-like growth factor 2 receptor) - Rat Genome Database
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Gene: Igf2r (insulin-like growth factor 2 receptor) Mus musculus
Analyze
Symbol: Igf2r
Name: insulin-like growth factor 2 receptor
RGD ID: 732661
MGI Page MGI
Description: Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; early conceptus; and genitourinary system. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hepatocellular carcinoma; in situ carcinoma (multiple); and nephroblastoma. Orthologous to human IGF2R (insulin like growth factor 2 receptor); PARTICIPATES IN renin-angiotensin cascade pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 300 kDa mannose 6-phosphate receptor; AI661837; cation-independent mannose 6-phosphate receptor; cation-independent mannose-6-phosphate receptor; cation-independent MPR; CD222; CI Man-6-P receptor; CI-; CI-MPR; IGF-II receptor; IGF-II/CI-MPR; insulin-like growth factor II receptor; M6P/IG; M6P/IGF2 receptor; M6P/IGF2R; M6PR; mannose-6-phosphate receptor, cation independent; MPR 300; Mpr3; Mpr300
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,901,293 - 12,988,593 (-)NCBIGRCm39mm39
GRCm39 Ensembl1712,901,293 - 12,988,551 (-)Ensembl
GRCm381712,682,406 - 12,769,706 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,682,406 - 12,769,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,875,272 - 12,962,572 (-)NCBIGRCm37mm9NCBIm37
MGSCv361712,525,771 - 12,613,022 (-)NCBImm8
Celera1712,714,412 - 12,801,753 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.64NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
acetylsalicylic acid  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
carboplatin  (ISO)
chloroacetaldehyde  (ISO)
chlorpyrifos  (ISO)
cidofovir anhydrous  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
cyclosporin A  (ISO)
DDE  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
disulfiram  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
elemental selenium  (ISO)
enzacamene  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
erythromycin estolate  (ISO)
ethanol  (EXP)
fenofibrate  (ISO)
finasteride  (ISO)
fipronil  (ISO)
folic acid  (EXP,ISO)
fulvestrant  (EXP,ISO)
genistein  (ISO)
ifosfamide  (ISO)
kojic acid  (ISO)
linuron  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
metformin  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nitrofen  (ISO)
p-menthan-3-ol  (ISO)
p-toluidine  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
prochloraz  (ISO)
procymidone  (ISO)
resveratrol  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
Tributyltin oxide  (EXP,ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP,ISO)
tungsten  (EXP)
tunicamycin  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal body water content  (IAGP)
abnormal bone ossification  (IAGP)
abnormal circulating hormone level  (IAGP)
abnormal craniofacial morphology  (IAGP)
abnormal embryonic growth/weight/body size  (IAGP)
abnormal external female genitalia morphology  (IAGP)
abnormal gait  (IAGP)
abnormal interventricular septum morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal lung morphology  (IAGP)
abnormal lysosome physiology  (IAGP)
abnormal maternal nurturing  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal myocardium layer morphology  (IAGP)
abnormal tail morphology  (IAGP)
abnormal tricuspid valve morphology  (IAGP)
abnormal uterine horn morphology  (IAGP)
abnormal uterus morphology  (IAGP)
absent endometrial glands  (IAGP)
absent suckling reflex  (IAGP)
congestive heart failure  (IAGP)
cyanosis  (IAGP)
decreased birth weight  (IAGP)
decreased body size  (IAGP)
decreased fetal weight  (IAGP)
decreased litter size  (IAGP)
decreased survivor rate  (IAGP)
dilated heart  (IAGP)
dilated heart left ventricle  (IAGP)
dilated heart right ventricle  (IAGP)
dilated uterine horn  (IAGP)
disorganized myocardium  (IAGP)
edema  (IAGP)
enlarged heart  (IAGP)
enlarged kidney  (IAGP)
enlarged liver  (IAGP)
enlarged lung  (IAGP)
enlarged placenta  (IAGP)
enlarged uterine horn  (IAGP)
enlarged uterus  (IAGP)
female infertility  (IAGP)
genetic imprinting  (IAGP)
heart hemorrhage  (IAGP)
heart hyperplasia  (IAGP)
impaired branching involved in preterminal bronchiole morphogenesis  (IAGP)
increased birth body size  (IAGP)
increased birth weight  (IAGP)
increased body size  (IAGP)
increased body weight  (IAGP)
increased brain size  (IAGP)
increased embryo size  (IAGP)
increased fetal size  (IAGP)
increased fetal weight  (IAGP)
increased heart right ventricle size  (IAGP)
increased heart ventricle size  (IAGP)
increased heart weight  (IAGP)
increased nucleated erythrocyte cell number  (IAGP)
increased placenta weight  (IAGP)
kinked tail  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
liver hyperplasia  (IAGP)
maternal imprinting  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
polydactyly  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature bone ossification  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, incomplete penetrance  (IAGP)
pulmonary hyperplasia  (IAGP)
reduced female fertility  (IAGP)
reduced male fertility  (IAGP)
respiratory distress  (IAGP)
respiratory failure  (IAGP)
short sternum  (IAGP)
short tail  (IAGP)
slow postnatal weight gain  (IAGP)
small placenta  (IAGP)
split sternum  (IAGP)
thick interventricular septum  (IAGP)
thick ventricular wall  (IAGP)
thin endometrium  (IAGP)
vagina atresia  (IAGP)
References

References - curated
1. Dagvajantsan B, etal., Tohoku J Exp Med. 2008 Apr;214(4):303-10.
2. De Souza AT, etal., Nat Genet. 1995 Dec;11(4):447-9.
3. Forejt J and Gregorova S, Cell 1992 Aug 7;70(3):443-50.
4. Hankins GR, etal., Oncogene. 1996 May 2;12(9):2003-9.
5. Jang HS, etal., World J Gastroenterol. 2008 Mar 7;14(9):1394-8. doi: 10.3748/wjg.14.1394.
6. Lau MM, etal., Genes Dev 1994 Dec 15;8(24):2953-63.
7. Lautem A, etal., Oncol Rep. 2019 Apr;41(4):2299-2310. doi: 10.3892/or.2019.6995. Epub 2019 Feb 1.
8. McCann JA, etal., J Clin Endocrinol Metab. 2004 Nov;89(11):5700-6.
9. MGD data from the GO Consortium
10. Mills JJ, etal., Oncogene. 1998 May 28;16(21):2797-802.
11. Nguyen G, Kidney Int. 2006 May;69(9):1503-6.
12. Oka Y, etal., Hepatology. 2002 May;35(5):1153-63. doi: 10.1053/jhep.2002.32669.
13. OMIM Disease Annotation Pipeline
14. Price WA, etal., Pediatr Res. 1992 Sep;32(3):291-5. doi: 10.1203/00006450-199209000-00009.
15. RGD automated import pipeline
16. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. RGD automated import pipeline for gene-chemical interactions
18. Sheng J, etal., BMC Cell Biol. 2004 Aug 27;5:32.
19. Tsujiuchi T, etal., Mol Carcinog 2003 Jan;36(1):32-7.
20. Tsujiuchi T, etal., Mol Carcinog. 2004 Apr;39(4):199-205.
21. Vicikova K, etal., Neoplasma. 2018 Sep 19;65(5):762-768. doi: 10.4149/neo_2018_171203N792. Epub 2018 Jun 18.
22. Villuendas G, etal., Eur J Endocrinol. 2006 Aug;155(2):331-6.
23. Wada I, etal., Hepatology. 1999 Jun;29(6):1718-21. doi: 10.1002/hep.510290635.
24. Xu YQ, etal., Oncogene. 1997 Mar 6;14(9):1041-6.
25. Yang EB, etal., Int J Mol Med. 2003 Jun;11(6):773-8.
26. Zakaria R, etal., Acta Histochem. 2009;111(1):52-60. Epub 2008 Aug 3.
Additional References at PubMed
PMID:1317321   PMID:1319896   PMID:1701096   PMID:1845916   PMID:1848553   PMID:1964408   PMID:2852162   PMID:2963825   PMID:2964085   PMID:7589806   PMID:7642711   PMID:7649473  
PMID:7691099   PMID:7720562   PMID:7750499   PMID:7871587   PMID:7894489   PMID:7956043   PMID:7984240   PMID:8012378   PMID:8050357   PMID:8050371   PMID:8068549   PMID:8076514  
PMID:8088706   PMID:8115355   PMID:8188212   PMID:8194771   PMID:8220428   PMID:8226743   PMID:8247120   PMID:8247133   PMID:8314083   PMID:8332218   PMID:8398121   PMID:8462104  
PMID:8543154   PMID:8565329   PMID:8565838   PMID:8584025   PMID:8706013   PMID:8707842   PMID:8806828   PMID:8854860   PMID:8875072   PMID:8889548   PMID:8947024   PMID:9076684  
PMID:9115713   PMID:9268631   PMID:9281335   PMID:9294199   PMID:9338788   PMID:9389646   PMID:9438420   PMID:9461565   PMID:9480908   PMID:9584126   PMID:9724044   PMID:9853964  
PMID:9858505   PMID:9988214   PMID:10101117   PMID:10212152   PMID:10226808   PMID:10341453   PMID:10349636   PMID:10521784   PMID:10601243   PMID:10641796   PMID:10779549   PMID:10802648  
PMID:10882106   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11105922   PMID:11115847   PMID:11217851   PMID:11290321   PMID:11311167   PMID:11532981   PMID:11544199   PMID:11562346  
PMID:11641723   PMID:11792812   PMID:11805093   PMID:11884597   PMID:11934864   PMID:12049782   PMID:12189157   PMID:12421715   PMID:12466851   PMID:12477932   PMID:12482959   PMID:12507915  
PMID:12520002   PMID:12627233   PMID:12729502   PMID:12853484   PMID:12906851   PMID:14566968   PMID:14585283   PMID:14985351   PMID:15078902   PMID:15163367   PMID:15210844   PMID:15215868  
PMID:15232000   PMID:15371683   PMID:15448183   PMID:15475262   PMID:15518240   PMID:15543235   PMID:15647320   PMID:15721138   PMID:15747579   PMID:15859358   PMID:16037066   PMID:16141072  
PMID:16141073   PMID:16179614   PMID:16204191   PMID:16214895   PMID:16575173   PMID:16575177   PMID:16602821   PMID:16631346   PMID:16987518   PMID:17039549   PMID:17077188   PMID:17182038  
PMID:17561313   PMID:17634284   PMID:17653731   PMID:17848585   PMID:18001291   PMID:18073203   PMID:18276788   PMID:18361416   PMID:18413996   PMID:18428025   PMID:18988810   PMID:19007310  
PMID:19136628   PMID:19141673   PMID:19195023   PMID:19228596   PMID:19727073   PMID:19762426   PMID:19794138   PMID:19884348   PMID:20132320   PMID:20168089   PMID:20200945   PMID:20541250  
PMID:20615935   PMID:20889566   PMID:21047779   PMID:21062905   PMID:21267068   PMID:21273553   PMID:21354127   PMID:21397538   PMID:21427161   PMID:21486933   PMID:21565611   PMID:21873635  
PMID:22154081   PMID:22159122   PMID:22521359   PMID:23031221   PMID:23085235   PMID:23239737   PMID:23444351   PMID:23468951   PMID:23563309   PMID:23584732   PMID:23806407   PMID:24090483  
PMID:24291790   PMID:24352558   PMID:24387305   PMID:24391734   PMID:24448824   PMID:24846272   PMID:25232016   PMID:25918552   PMID:25990242   PMID:26098312   PMID:26267271   PMID:26369386  
PMID:26370502   PMID:27167200   PMID:27861515   PMID:28378742   PMID:28671696   PMID:28708136   PMID:28806168   PMID:29475039   PMID:29483092   PMID:30216384   PMID:30704515   PMID:31329595  
PMID:31388182   PMID:32325033   PMID:32369018   PMID:33057429  


Genomics

Comparative Map Data
Igf2r
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,901,293 - 12,988,593 (-)NCBIGRCm39mm39
GRCm39 Ensembl1712,901,293 - 12,988,551 (-)Ensembl
GRCm381712,682,406 - 12,769,706 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,682,406 - 12,769,664 (-)EnsemblGRCm38mm10GRCm38
MGSCv371712,875,272 - 12,962,572 (-)NCBIGRCm37mm9NCBIm37
MGSCv361712,525,771 - 12,613,022 (-)NCBImm8
Celera1712,714,412 - 12,801,753 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.64NCBI
IGF2R
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6159,969,099 - 160,113,507 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl6159,969,082 - 160,113,507 (+)EnsemblGRCh38hg38GRCh38
GRCh386159,969,082 - 160,111,504 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376160,390,114 - 160,532,536 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,310,121 - 160,447,573 (+)NCBINCBI36hg18NCBI36
Build 346160,360,541 - 160,497,992NCBI
Celera6161,035,974 - 161,173,355 (+)NCBI
Cytogenetic Map6q25.3NCBI
HuRef6157,860,740 - 157,998,270 (+)NCBIHuRef
CHM1_16160,652,348 - 160,794,781 (+)NCBICHM1_1
Igf2r
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2147,979,109 - 48,067,501 (+)NCBI
Rnor_6.0 Ensembl148,176,106 - 48,264,477 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0148,176,095 - 48,264,482 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0151,488,767 - 51,577,141 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,253,273 - 42,341,646 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,256,217 - 42,344,589 (+)NCBI
Celera143,778,518 - 43,867,238 (+)NCBICelera
Cytogenetic Map1q11NCBI
Igf2r
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,752,855 - 20,851,281 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,754,915 - 20,874,759 (-)NCBIChiLan1.0ChiLan1.0
IGF2R
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16162,884,786 - 162,983,968 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,878,661 - 162,997,762 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06157,852,565 - 157,990,049 (+)NCBIMhudiblu_PPA_v0panPan3
IGF2R
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl149,161,444 - 49,262,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1149,161,551 - 49,262,260 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Igf2r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493648911,447,043 - 11,523,695 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGF2R
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,368,103 - 7,472,548 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,369,485 - 7,472,480 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,168,321 - 9,271,328 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGF2R
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,587,717 - 87,723,795 (+)NCBI
ChlSab1.1 Ensembl1387,587,907 - 87,724,116 (+)Ensembl
Igf2r
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248552,752,676 - 2,887,327 (-)NCBI

Position Markers
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv371712,875,756 - 12,875,895UniSTSGRCm37
MGSCv371712,875,399 - 12,875,518UniSTSGRCm37
Celera1712,714,896 - 12,715,035UniSTS
Celera1712,714,539 - 12,714,658UniSTS
Cytogenetic Map17A-CUniSTS
cM Map177.35UniSTS
cM Map177.35UniSTS
cM Map177.35UniSTS
AI661837  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,769,757 - 12,769,871UniSTSGRCm38
MGSCv371712,962,623 - 12,962,737UniSTSGRCm37
Celera1712,801,804 - 12,801,918UniSTS
Cytogenetic Map17A-CUniSTS
Cytogenetic Map17A1UniSTS
cM Map178.66UniSTS
Whitehead/MRC_RH17215.09UniSTS
25.mHAa3f1.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,723,607 - 12,723,778UniSTSGRCm38
MGSCv371712,916,473 - 12,916,644UniSTSGRCm37
Celera1712,755,616 - 12,755,787UniSTS
Cytogenetic Map17A-CUniSTS
Whitehead_YAC17 UniSTS
UniSTS:237576  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,746,022 - 12,746,324UniSTSGRCm38
MGSCv371712,938,888 - 12,939,190UniSTSGRCm37
Celera1712,778,071 - 12,778,373UniSTS
Cytogenetic Map17A-CUniSTS
Cytogenetic Map17A1UniSTS
cM Map178.66UniSTS
PMC136958P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,741,564 - 12,741,734UniSTSGRCm38
MGSCv371712,934,430 - 12,934,600UniSTSGRCm37
Celera1712,773,530 - 12,773,700UniSTS
Cytogenetic Map17A-CUniSTS
Cytogenetic Map17A1UniSTS
cM Map178.66UniSTS
PMC136958P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,683,902 - 12,684,126UniSTSGRCm38
MGSCv371712,876,768 - 12,876,992UniSTSGRCm37
Celera1712,715,908 - 12,716,132UniSTS
Cytogenetic Map17A-CUniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS
cM Map177.35UniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS
cM Map177.35UniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,682,533 - 12,682,652UniSTSGRCm38
MGSCv371712,875,399 - 12,875,518UniSTSGRCm37
Celera1712,714,539 - 12,714,658UniSTS
Cytogenetic Map17A-CUniSTS
cM Map177.35UniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,682,890 - 12,683,029UniSTSGRCm38
MGSCv371712,875,756 - 12,875,895UniSTSGRCm37
Celera1712,714,896 - 12,715,035UniSTS
Cytogenetic Map17A-CUniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS
Airn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,742,869 - 12,743,095UniSTSGRCm38
Celera1712,774,918 - 12,775,144UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map17A-CUniSTS
Airn  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,744,478 - 12,745,047UniSTSGRCm38
Celera1712,776,527 - 12,777,096UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map17A-CUniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS
Igf2r  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map17A-CUniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120924747Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120924747Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125443244Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17125970523Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17125975624Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17126862710Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17126862710Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17128979566Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17128979566Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17128979566Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17130809908Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17312791337128037Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17392461526182159Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17392461548559063Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17480447727496965Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined480447745359340Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17480447746158776Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17480447747574740Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined480447765330362Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17667496240674962Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17765701129268449Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17836594042366175Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17836594042366175Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined17986241186688972Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171065914544659245Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1098759739053168Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1166699745667145Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171177921045779210Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1197944224857795Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171206732483054339Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171223281346232813Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171241779526182159Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171242798746427987Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:910
Count of miRNA genes:509
Interacting mature miRNAs:617
Transcripts:ENSMUST00000024599, ENSMUST00000159127, ENSMUST00000161738, ENSMUST00000162982
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC116804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC167817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF151173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF481054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH001977 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ249895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY644391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB865604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC043457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC115601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC171973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP757292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ900123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA324933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD545656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF167933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK639250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN461279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN530622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ425888 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ425889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M58586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M97300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U04710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U26348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000024599   ⟹   ENSMUSP00000024599
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1712,682,406 - 12,769,664 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159127
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1712,748,653 - 12,750,800 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161738
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1712,698,527 - 12,701,279 (-)Ensembl
RefSeq Acc Id: NM_010515   ⟹   NP_034645
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391712,901,293 - 12,988,593 (-)NCBI
GRCm381712,682,406 - 12,769,706 (-)ENTREZGENE
MGSCv371712,875,272 - 12,962,572 (-)RGD
Celera1712,714,412 - 12,801,753 (-)RGD
cM Map17 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034645   ⟸   NM_010515
- Peptide Label: precursor
- UniProtKB: Q07113 (UniProtKB/Swiss-Prot),   Q8C6V9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000024599   ⟸   ENSMUST00000024599
Protein Domains
Fibronectin type-II   MRH

Promoters
RGD ID:13674756
Promoter ID:EPDNEW_M21527
Type:initiation region
Name:Igf2r_1
Description:Mus musculus insulin-like growth factor 2 receptor , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381712,769,654 - 12,769,714EPDNEW
RGD ID:6828254
Promoter ID:MM_KWN:22120
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_010515
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361712,962,249 - 12,962,749 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96435 AgrOrtholog
Ensembl Genes ENSMUSG00000023830 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000024599 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000024599 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.130.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CIMR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN_type2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN_type2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Man6P_isomerase_rcpt-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96435 ENTREZGENE
NCBI Gene 16004 ENTREZGENE
Pfam CIMR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  fn2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Igf2r PhenoGen
PROSITE FN2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRH UniProtKB/Swiss-Prot
SMART FN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B7ZWC4_MOUSE UniProtKB/TrEMBL
  B9EKB8_MOUSE UniProtKB/TrEMBL
  MPRI_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q7TMR1_MOUSE UniProtKB/TrEMBL
  Q80VF2_MOUSE UniProtKB/TrEMBL
  Q8C2F9_MOUSE UniProtKB/TrEMBL
  Q8C6V9 ENTREZGENE, UniProtKB/TrEMBL
  Q8K0J1_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q61822 UniProtKB/Swiss-Prot
  Q6LED1 UniProtKB/Swiss-Prot