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Gene: Sod2 (superoxide dismutase 2, mitochondrial) Mus musculus
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Symbol: Sod2
Name: superoxide dismutase 2, mitochondrial
Description: Exhibits superoxide dismutase activity. Involved in several processes, including animal organ development; apoptotic signaling pathway; and regulation of cellular biosynthetic process. Localizes to the mitochondrion. Used to study Canavan disease; Leigh disease; amyotrophic lateral sclerosis type 1; congestive heart failure; and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); diabetes mellitus (multiple); endocrine gland cancer (multiple); lipid storage disease (multiple); and optic nerve disease (multiple). Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Orthologous to human SOD2 (superoxide dismutase 2); PARTICIPATES IN hypertension pathway; Huntington's disease pathway; INTERACTS WITH (+)-catechin; (-)-epigallocatechin 3-gallate; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: manganese SOD; manganese superoxide dismutase; MGC6144; MnSOD; Sod-2; superoxide dismutase [Mn], mitochondrial
Orthologs:
Homo sapiens (human) : SOD2 (superoxide dismutase 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sod2 (superoxide dismutase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod2 (superoxide dismutase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD2 (superoxide dismutase 2)
Canis lupus familiaris (dog) : SOD2 (superoxide dismutase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sod2 (superoxide dismutase 2)
Sus scrofa (pig) : SOD2 (superoxide dismutase 2)
Chlorocebus sabaeus (green monkey) : SOD2 (superoxide dismutase 2)
Heterocephalus glaber (naked mole-rat) : Sod2 (superoxide dismutase 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1713,006,846 - 13,040,063 (+)Ensembl
GRCm381713,007,839 - 13,018,119 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371713,200,705 - 13,210,985 (+)NCBIGRCm37mm9NCBIm37
MGSCv361712,850,771 - 12,861,051 (+)NCBImm8
Celera1713,040,822 - 13,051,101 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model