Sod2 (superoxide dismutase 2, mitochondrial) - Rat Genome Database
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Gene: Sod2 (superoxide dismutase 2, mitochondrial) Mus musculus
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Symbol: Sod2
Name: superoxide dismutase 2, mitochondrial
RGD ID: 11330
MGI Page MGI
Description: Exhibits superoxide dismutase activity. Involved in several processes, including animal organ development; apoptotic signaling pathway; and regulation of cellular biosynthetic process. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and sensory organ. Used to study Canavan disease; Leigh disease; amyotrophic lateral sclerosis type 1; congestive heart failure; and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); lipid storage disease (multiple); liver disease (multiple); and optic nerve disease (multiple). Orthologous to human SOD2 (superoxide dismutase 2); PARTICIPATES IN hypertension pathway; Huntington's disease pathway; INTERACTS WITH (+)-catechin; (-)-epigallocatechin 3-gallate; (R)-lipoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: manganese SOD; manganese superoxide dismutase; MGC6144; Mn; MnSOD; Sod; Sod-2; superoxide dismutase [Mn], mitochondrial
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
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Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,226,726 - 13,237,006 (+)NCBIGRCm39mm39
GRCm381713,007,839 - 13,018,119 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1713,006,846 - 13,040,063 (+)EnsemblGRCm38mm10GRCm38
MGSCv371713,200,705 - 13,210,985 (+)NCBIGRCm37mm9NCBIm37
MGSCv361712,850,771 - 12,861,051 (+)NCBImm8
Celera1713,040,822 - 13,051,101 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model