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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11330
Species: Mus musculus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2, mitochondrial
Acc ID: CHEBI:15756
Term: hexadecanoic acid
Definition: A straight-chain, sixteen-carbon, saturated long-chain fatty acid.
Chemical ID: MESH:D019308
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2decreases expressionISOSod2 (Rattus norvegicus)6480464CTDPalmitic Acid results in decreased expression of SOD2 mRNA; Palmitic Acid results in decreased expression of SOD2 proteinPMID:28027979
Sod2increases expressionISOSod2 (Rattus norvegicus)6480464CTDPalmitic Acid results in increased expression of SOD2 mRNAPMID:24349266
Sod2multiple interactionsISOSod2 (Rattus norvegicus)6480464CTD[osteum co-treated with Palmitic Acid] results in decreased expression of SOD2 proteinPMID:35798905
Sod2multiple interactionsISOSOD2 (Homo sapiens)6480464CTD[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNAPMID:30547786
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