Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11330
Species: Mus musculus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2, mitochondrial
Acc ID: CHEBI:8666
Term: Pyridostigmine bromide
Definition: null
Chemical ID: MESH:D011729
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2decreases expressionISOSOD2 (Homo sapiens)6480464CTDPyridostigmine Bromide results in decreased expression of SOD2 mRNAPMID:31175926
Sod2multiple interactionsISOSod2 (Rattus norvegicus)6480464CTD[Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of SOD2 mRNAPMID:28659758
Sod2multiple interactionsISOSOD2 (Homo sapiens)6480464CTDSOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of CASP8 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide affects the expression of SOD1 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of BAX mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of CASP3 mRNA]; SOD2 protein SNP affects the reaction [Pyridostigmine Bromide results in decreased expression of CASP3 protein]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of BCL2 mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of CAT mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of DNMT1 mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of GPX1 mRNA]; SOD2 protein SNP inhibits the reaction [Pyridostigmine Bromide results in decreased expression of SOD2 mRNA]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of ACHE protein]; SOD2 protein SNP promotes the reaction [Pyridostigmine Bromide results in decreased expression of BAX protein]PMID:31175926
Go Back to source page   Continue to Ontology report