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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11330
Species: Mus musculus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2, mitochondrial
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2decreases activityEXP 6480464CTDmethylmercuric chloride results in decreased activity of SOD2 proteinPMID:21781743
Sod2decreases expressionEXP 6480464CTDmethylmercuric chloride results in decreased expression of SOD2 mRNA; methylmercuric chloride results in decreased expression of SOD2 proteinPMID:33301842
Sod2increases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of SOD2 proteinPMID:33338554
Sod2multiple interactionsEXP 6480464CTD[GHRL protein co-treated with methylmercuric chloride] results in decreased expression of SOD2 proteinPMID:33301842
Sod2decreases expressionISOSod2 (Rattus norvegicus)6480464CTDmethylmercuric chloride results in decreased expression of SOD2 proteinPMID:29258870
Sod2decreases expressionISOSOD2 (Homo sapiens)6480464CTDmethylmercuric chloride results in decreased expression of SOD2 mRNAPMID:29581082
Sod2increases expressionISOSOD2 (Homo sapiens)6480464CTDmethylmercuric chloride results in increased expression of SOD2 mRNAPMID:28001369
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