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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11330
Species: Mus musculus
RGD Object: Gene
Symbol: Sod2
Name: superoxide dismutase 2, mitochondrial
Acc ID: CHEBI:8198
Term: trans-piceid
Definition: A stilbenoid that is trans-resveratrol substituted at position 3 by a beta-D-glucosyl residue.
Chemical ID: MESH:C058229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sod2increases expressionEXP 6480464CTDpolydatin results in increased expression of SOD2 proteinPMID:24361291
Sod2multiple interactionsEXP 6480464CTDESR2 gene mutant form inhibits the reaction [polydatin results in increased expression of SOD2 protein]; fulvestrant inhibits the reaction [polydatin results in increased expression of SOD2 protein]PMID:24361291
Sod2multiple interactionsISOSOD2 (Homo sapiens)6480464CTDpolydatin results in increased expression of and results in increased activity of SOD2 proteinPMID:24361291
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