Fas (Fas (TNF receptor superfamily member 6)) - Rat Genome Database

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Gene: Fas (Fas (TNF receptor superfamily member 6)) Mus musculus
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Symbol: Fas
Name: Fas (TNF receptor superfamily member 6)
RGD ID: 1552455
MGI Page MGI
Description: Enables identical protein binding activity. Involved in extrinsic apoptotic signaling pathway via death domain receptors and positive regulation of protein-containing complex assembly. Acts upstream of or within several processes, including activation-induced cell death of T cells; hematopoietic or lymphoid organ development; and regulation of hemopoiesis. Located in external side of plasma membrane and extracellular region. Part of CD95 death-inducing signaling complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study Sjogren's syndrome; autoimmune lymphoproliferative syndrome; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); cystic fibrosis; hematologic cancer (multiple); pre-eclampsia (multiple); and urinary system cancer (multiple). Orthologous to human FAS (Fas cell surface death receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI196731; AP; APO-1; apo-1 antigen; APO1; apoptosis-mediating surface antigen FAS; APT1; CD95; Fas (TNF receptor superfamily member); Fas antigen; FASLG receptor; lpr; lymphoproliferation; TNF; Tnfr; TNFR6; Tnfrsf6; tumor necrosis factor receptor superfamily member 6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
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Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391934,267,926 - 34,305,175 (+)NCBIGRCm39mm39
GRCm39 Ensembl1934,268,066 - 34,305,172 (+)Ensembl
GRCm381934,290,647 - 34,327,775 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1934,290,666 - 34,327,772 (+)EnsemblGRCm38mm10GRCm38
MGSCv371934,365,149 - 34,402,260 (+)NCBIGRCm37mm9NCBIm37
MGSCv361934,356,663 - 34,393,767 (+)NCBImm8
Celera1935,067,780 - 35,104,920 (+)NCBICelera
Cytogenetic Map19C1NCBI
cM Map1929.48NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model