Apob (apolipoprotein B) - Rat Genome Database

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Gene: Apob (apolipoprotein B) Mus musculus
Analyze
Symbol: Apob
Name: apolipoprotein B
RGD ID: 735788
MGI Page MGI
Description: Predicted to enable several functions, including cholesterol transfer activity; heparin binding activity; and lipase binding activity. Acts upstream of or within several processes, including cholesterol efflux; lipoprotein metabolic process; and triglyceride metabolic process. Located in endoplasmic reticulum. Is expressed in several structures, including extraembryonic component; gut; liver; metencephalon roof; and placenta. Used to study familial hypobetalipoproteinemia 2. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Orthologous to human APOB (apolipoprotein B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI315052; Apo B-100; apob-; apob-100; apob-48; apolipoprotein B-100; MGC176318
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39128,027,629 - 8,066,839 (+)NCBIGRCm39mm39
GRCm39 Ensembl128,027,648 - 8,066,835 (+)Ensembl
GRCm38127,977,629 - 8,016,839 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl127,977,648 - 8,016,835 (+)EnsemblGRCm38mm10GRCm38
MGSCv37127,984,483 - 8,023,645 (+)NCBIGRCm37mm9NCBIm37
MGSCv36128,003,656 - 8,042,849 (+)NCBImm8
Celera128,374,429 - 8,411,685 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map123.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
aortic valve stenosis  (ISO)
arteriosclerosis  (ISO)
Behcet's disease  (ISO)
beta thalassemia  (ISO)
bile duct cancer  (ISO)
biliary tract cancer  (ISO)
cardiovascular system disease  (ISO)
celiac disease  (ISO)
cerebral infarction  (ISO)
common bile duct neoplasm  (ISO)
coronary artery disease  (ISO)
Coronary Disease  (ISO)
Coumarin Sensitivity  (ISO)
Death  (ISO)
diabetes mellitus  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
dilated cardiomyopathy 1B  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
Dyslipidemias  (ISO)
Endotoxemia  (ISO)
Experimental Diabetes Mellitus  (ISO)
familial combined hyperlipidemia  (ISO)
familial hypercholesterolemia  (ISO)
Familial Hypercholesterolemia due to Ligand-Defective Apolipoprotein B  (ISO)
familial hyperlipidemia  (IMP,ISO)
familial hypobetalipoproteinemia 1  (ISO)
familial hypobetalipoproteinemia 2  (IEA)
Familial Hypobetalipoproteinemia, Apolipoprotein B  (ISO)
familial isolated deficiency of vitamin E  (ISO)
fatty liver disease  (ISO)
gallbladder cancer  (ISO)
genetic disease  (ISO)
Hemorrhage  (ISO)
Hypercholesterolemia  (ISO)
Hypercholesterolemia, Autosomal Dominant, 3  (ISO)
Hyperlipoproteinemia Type II  (ISO)
hypertension  (ISO)
Hypertriglyceridemia  (ISO)
hypobetalipoproteinemia  (ISO)
Marfanoid Mental Retardation Syndrome, Autosomal  (ISO)
Metabolic Syndrome  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
nephrotic syndrome  (ISO)
obesity  (IEP,ISO)
ovarian cancer  (ISO)
peripheral vascular disease  (ISO)
sickle cell anemia  (ISO)
spastic ataxia  (ISO)
Sudden Cardiac Death  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
warfarin resistance  (ISO)
warfarin sensitivity  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-taxifolin  (ISO)
(-)-ephedrine  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
1,2-dimethylhydrazine  (EXP)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-sulfonyldiphenol  (EXP)
5-fluorouracil  (ISO)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
acetamide  (ISO)
acetic anhydride  (ISO)
acetylleucyl-leucyl-norleucinal  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
allopurinol  (ISO)
aluminium atom  (ISO)
aluminium(0)  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
atenolol  (ISO)
atorvastatin calcium  (ISO)
benazepril  (ISO)
bendroflumethiazide  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
Benzo[k]fluoranthene  (EXP)
beta-D-glucosamine  (ISO)
bexarotene  (ISO)
bezafibrate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buspirone  (ISO)
buta-1,3-diene  (EXP)
cadmium atom  (ISO)
caffeine  (ISO)
calcidiol  (ISO)
capsaicin  (ISO)
carbon nanotube  (EXP)
cefaloridine  (ISO)
cholesterol  (ISO)
choline  (EXP)
chromium(6+)  (EXP)
chrysin  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cortisol  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
daunorubicin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diethyl pyrocarbonate  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
ethanolamine  (ISO)
fenofibrate  (ISO)
ferulic acid  (EXP)
flavonoids  (ISO)
flutamide  (ISO)
fluvastatin  (ISO)
folic acid  (EXP,ISO)
fructose  (EXP,ISO)
gadolinium trichloride  (ISO)
gallic acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gemfibrozil  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
graphite  (ISO)
GW 4064  (EXP,ISO)
GW 7647  (ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
indinavir  (ISO)
indometacin  (ISO)
irbesartan  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (EXP)
lactacystin  (ISO)
levonorgestrel  (ISO)
linsidomine  (ISO)
lovastatin  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
mifepristone  (ISO)
morphine  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
Nandrolone decanoate  (ISO)
nickel atom  (ISO)
nicotinic acid  (ISO)
nitrofen  (ISO)
Nonylphenol  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (ISO)
olanzapine  (ISO)
oleic acid  (ISO)
palmitoyl ethanolamide  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
Propiverine  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
rifampicin  (ISO)
rimonabant  (EXP)
rosuvastatin calcium  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
simvastatin  (ISO)
sodium acetate trihydrate  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
sulindac  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP)
tolcapone  (ISO)
tremolite asbestos  (EXP)
trichloroethene  (EXP)
triptonide  (EXP)
troglitazone  (ISO)
tunicamycin  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
warfarin  (ISO)
wortmannin  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal aorta bulb morphology  (IAGP)
abnormal aortic valve morphology  (IAGP)
abnormal blood homeostasis  (IAGP)
abnormal cardiovascular system physiology  (IAGP)
abnormal cholesterol homeostasis  (IAGP)
abnormal circulating cholesterol level  (IAGP)
abnormal circulating HDL cholesterol level  (IAGP)
abnormal embryo development  (IAGP)
abnormal eye electrophysiology  (IAGP)
abnormal fasting circulating glucose level  (IAGP)
abnormal heart left ventricle morphology  (IAGP)
abnormal heart ventricles weight  (IAGP)
abnormal retinal pigment epithelium morphology  (IAGP)
abnormal triglyceride level  (IAGP)
abnormal visceral yolk sac endoderm morphology  (IAGP)
aortic valve stenosis  (IAGP)
aortitis  (IAGP)
asthenozoospermia  (IAGP)
atherosclerotic lesions  (IAGP)
calcified aortic valve  (IAGP)
cardiac fibrosis  (IAGP)
cardiac hypertrophy  (IAGP)
decreased body weight  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased circulating cholesterol level  (IAGP)
decreased circulating HDL cholesterol level  (IAGP)
decreased circulating LDL cholesterol level  (IAGP)
decreased circulating triglyceride level  (IAGP)
decreased circulating VLDL cholesterol level  (IAGP)
decreased embryo size  (IAGP)
decreased susceptibility to atherosclerosis  (IAGP)
embryonic lethality during organogenesis, incomplete penetrance  (IAGP)
exencephaly  (IAGP)
heart left ventricle hypertrophy  (IAGP)
hemorrhage  (IAGP)
hepatic steatosis  (IAGP)
herniated liver  (IAGP)
hydrocephaly  (IAGP)
hyperglycemia  (IAGP)
hypertension  (IAGP)
impaired glucose tolerance  (IAGP)
impaired sperm penetration of zona pellucida  (IAGP)
increased body weight  (IAGP)
increased cardiac output  (IAGP)
increased cardiac stroke volume  (IAGP)
increased circulating cholesterol level  (IAGP)
increased circulating free fatty acids level  (IAGP)
increased circulating glucose level  (IAGP)
increased circulating HDL cholesterol level  (IAGP)
increased circulating insulin level  (IAGP)
increased circulating LDL cholesterol level  (IAGP)
increased circulating triglyceride level  (IAGP)
increased circulating VLDL cholesterol level  (IAGP)
increased circulating VLDL triglyceride level  (IAGP)
increased susceptibility to atherosclerosis  (IAGP)
obese  (IAGP)
oligozoospermia  (IAGP)
postnatal lethality  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
reduced male fertility  (IAGP)
References

References - curated
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6. Avakian SD, etal., Clin Genet. 2001 Nov;60(5):381-4.
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15. Dhingra S and Bansal MP, Chem Biol Interact. 2006 May 15;161(1):49-56. Epub 2006 Apr 3.
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24. Maioli M, etal., Atherosclerosis. 1997 May;131(1):127-33.
25. MGD and Homologene mouse data transfer
26. MGD data from the GO Consortium
27. MGD IEA
28. Mulvihill EE, etal., Diabetes. 2009 Oct;58(10):2198-210. Epub 2009 Jul 10.
29. Nakajima K, etal., Atherosclerosis. 2006 Oct 10;.
30. Niemi J, etal., Ann Med. 2009 May 1:1-11.
31. OMIM Disease Annotation Pipeline
32. Pan JP, etal., J Formos Med Assoc. 1998 Apr;97(4):233-8.
33. Pandey SN, etal., Liver Int. 2007 Sep;27(7):1008-15.
34. Pei WD, etal., Int J Cardiol. 2007 Feb 14;115(3):293-6. Epub 2006 Jun 22.
35. Pei WD, etal., Int J Cardiol. 2007 Mar 20;116(2):194-200. Epub 2006 Jul 10.
36. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
37. RGD automated import pipeline
38. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
39. RGD automated import pipeline for gene-chemical interactions
40. Saad MF, etal., Diabetes Care. 2004 Jun;27(6):1324-9.
41. Scoffone HM, etal., Am J Cardiol. 2013 Nov 1;112(9):1499-504. doi: 10.1016/j.amjcard.2013.06.035. Epub 2013 Sep 13.
42. Shearer GC, etal., Kidney Int. 2001 Jan;59(1):179-89.
43. Soutar AK and Naoumova RP, Nat Clin Pract Cardiovasc Med. 2007 Apr;4(4):214-25.
44. Su JW, etal., Diabetes Care. 2009 Feb;32(2):e21.
45. Tseng CH Clin Biochem. 2009 Jul;42(10-11):1019-24. Epub 2009 Mar 24.
46. Tybjaerg-Hansen A, etal., N Engl J Med. 1998 May 28;338(22):1577-84.
47. Warden CH, etal., Genomics 1993 Nov;18(2):295-307.
48. West NA, etal., Diabetes Care. 2009 Jan;32(1):175-80. Epub 2008 Oct 22.
49. Young SG, etal., J Clin Invest. 1987 Jun;79(6):1842-51.
Additional References at PubMed
PMID:1352323   PMID:1479285   PMID:1971301   PMID:2166832   PMID:2332175   PMID:2575591   PMID:2627199   PMID:3034900   PMID:6099394   PMID:7592581   PMID:7593600   PMID:7597652  
PMID:7658156   PMID:7671812   PMID:7677778   PMID:7733512   PMID:7741021   PMID:7803821   PMID:7878058   PMID:8044422   PMID:8170356   PMID:8254057   PMID:8409768   PMID:8460149  
PMID:8499655   PMID:8631881   PMID:8662599   PMID:8672142   PMID:8675665   PMID:8692825   PMID:8798769   PMID:8827514   PMID:8833235   PMID:8833906   PMID:8855280   PMID:8921909  
PMID:8995758   PMID:9026532   PMID:9202070   PMID:9226457   PMID:9494081   PMID:9502790   PMID:9507992   PMID:9539774   PMID:9598327   PMID:9633945   PMID:9717714   PMID:9788969  
PMID:9799833   PMID:9832509   PMID:9852051   PMID:10064308   PMID:10064312   PMID:10349636   PMID:10393218   PMID:10553000   PMID:10588944   PMID:10656920   PMID:10705993   PMID:10713055  
PMID:10744773   PMID:10859308   PMID:10893242   PMID:10922068   PMID:10926756   PMID:11002334   PMID:11042159   PMID:11076861   PMID:11120757   PMID:11208732   PMID:11217851   PMID:11331277  
PMID:11389586   PMID:11420610   PMID:11544199   PMID:11598138   PMID:11839763   PMID:11884293   PMID:12016514   PMID:12040188   PMID:12072432   PMID:12235184   PMID:12466851   PMID:12477932  
PMID:12493769   PMID:12615667   PMID:12628954   PMID:12816761   PMID:13130124   PMID:14634011   PMID:14679168   PMID:15024002   PMID:15105414   PMID:15124019   PMID:15265030   PMID:15342689  
PMID:15480992   PMID:15654123   PMID:15654758   PMID:15766748   PMID:15790761   PMID:15863839   PMID:15904874   PMID:16055734   PMID:16109169   PMID:16129816   PMID:16141072   PMID:16141073  
PMID:16175613   PMID:16204232   PMID:16230502   PMID:16343994   PMID:16380418   PMID:16455790   PMID:16461842   PMID:16498401   PMID:16798720   PMID:16920700   PMID:16921198   PMID:16957181  
PMID:17075015   PMID:17431188   PMID:17496333   PMID:17606262   PMID:17702862   PMID:17720994   PMID:17872464   PMID:17983586   PMID:18006607   PMID:18160459   PMID:18252207   PMID:18272520  
PMID:18369455   PMID:18385042   PMID:18497885   PMID:18502767   PMID:18519977   PMID:18617647   PMID:18645210   PMID:18722179   PMID:18794388   PMID:19020660   PMID:19026012   PMID:19386592  
PMID:19433756   PMID:19460358   PMID:19513531   PMID:19542564   PMID:19815815   PMID:19834103   PMID:19845970   PMID:20080679   PMID:20231283   PMID:20439543   PMID:20541607   PMID:20609438  
PMID:21267068   PMID:21339485   PMID:21357823   PMID:21372297   PMID:21398511   PMID:21533112   PMID:21546607   PMID:21562077   PMID:21677750   PMID:21778422   PMID:21779326   PMID:21784065  
PMID:21826528   PMID:21873635   PMID:22100249   PMID:22144466   PMID:22144566   PMID:22209213   PMID:22212222   PMID:22363685   PMID:22580899   PMID:22751103   PMID:22837469   PMID:22897442  
PMID:22982464   PMID:23029362   PMID:23059459   PMID:23099354   PMID:23307875   PMID:23505495   PMID:23580231   PMID:23643485   PMID:23676495   PMID:23804810   PMID:23922490   PMID:24349031  
PMID:24586211   PMID:24723556   PMID:24866382   PMID:24903096   PMID:24916387   PMID:24925974   PMID:25009997   PMID:25070550   PMID:25201910   PMID:25231636   PMID:25316721   PMID:25404299  
PMID:25474352   PMID:25765938   PMID:25830298   PMID:26044581   PMID:26178198   PMID:26775176   PMID:26786161   PMID:27133569   PMID:27297735   PMID:28031458   PMID:28062492   PMID:28457625  
PMID:28694219   PMID:28711866   PMID:28912302   PMID:28935571   PMID:28978771   PMID:29518331   PMID:29539583   PMID:29588316   PMID:29643120   PMID:30354205   PMID:30420641   PMID:30508567  
PMID:31526472   PMID:32325033   PMID:32703007   PMID:32788595   PMID:32861845   PMID:33302058   PMID:33542347  


Genomics

Comparative Map Data
Apob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39128,027,629 - 8,066,839 (+)NCBIGRCm39mm39
GRCm39 Ensembl128,027,648 - 8,066,835 (+)Ensembl
GRCm38127,977,629 - 8,016,839 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl127,977,648 - 8,016,835 (+)EnsemblGRCm38mm10GRCm38
MGSCv37127,984,483 - 8,023,645 (+)NCBIGRCm37mm9NCBIm37
MGSCv36128,003,656 - 8,042,849 (+)NCBImm8
Celera128,374,429 - 8,411,685 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map123.53NCBI
APOB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl221,001,429 - 21,044,073 (-)EnsemblGRCh38hg38GRCh38
GRCh38221,001,429 - 21,044,073 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37221,224,301 - 21,266,945 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36221,077,806 - 21,120,450 (-)NCBINCBI36hg18NCBI36
Build 34221,135,952 - 21,178,597NCBI
Celera221,063,779 - 21,106,429 (-)NCBI
Cytogenetic Map2p24.1NCBI
HuRef220,956,976 - 20,999,627 (-)NCBIHuRef
CHM1_1221,153,564 - 21,196,210 (-)NCBICHM1_1
Apob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2630,844,386 - 30,883,983 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl630,844,368 - 30,892,497 (+)Ensembl
Rnor_6.0633,176,826 - 33,216,381 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl633,176,778 - 33,224,997 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0642,956,372 - 42,995,922 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4631,508,060 - 31,548,083 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1631,546,139 - 31,550,758 (+)NCBI
Celera630,299,724 - 30,339,330 (+)NCBICelera
Cytogenetic Map6q14NCBI
Apob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554693,436,450 - 3,478,424 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554693,437,422 - 3,478,408 (-)NCBIChiLan1.0ChiLan1.0
APOB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A21,100,349 - 21,142,545 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A21,100,356 - 21,145,129 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A20,986,464 - 21,029,004 (-)NCBIMhudiblu_PPA_v0panPan3
APOB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11715,877,937 - 15,916,032 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1715,878,244 - 15,915,135 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1715,842,555 - 15,879,853 (-)NCBI
ROS_Cfam_1.01716,030,075 - 16,067,405 (-)NCBI
UMICH_Zoey_3.11715,883,776 - 15,920,986 (-)NCBI
UNSW_CanFamBas_1.01715,891,112 - 15,928,422 (-)NCBI
UU_Cfam_GSD_1.01715,923,305 - 15,960,613 (-)NCBI
Apob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629260,290,128 - 60,327,775 (-)NCBI
SpeTri2.0NW_00493649310,509,118 - 10,549,144 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
APOB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3117,250,096 - 117,316,200 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13117,250,096 - 117,316,200 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap3q24-qterNCBI
APOB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11486,624,209 - 86,669,175 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1486,624,332 - 86,668,704 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604525,515,337 - 25,558,432 (-)NCBIVero_WHO_p1.0
Apob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247383,579,747 - 3,622,508 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AI315052  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38128,015,759 - 8,015,964UniSTSGRCm38
MGSCv37128,022,565 - 8,022,770UniSTSGRCm37
Celera128,410,605 - 8,410,810UniSTS
Cytogenetic Map12A1.1UniSTS
Whitehead/MRC_RH12112.01UniSTS
UniSTS:236804  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38128,016,031 - 8,016,150UniSTSGRCm38
MGSCv37128,022,837 - 8,022,956UniSTSGRCm37
Celera128,410,877 - 8,410,996UniSTS
Cytogenetic Map12A1.1UniSTS
Apob  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38127,976,776 - 7,976,905UniSTSGRCm38
MGSCv37127,983,582 - 7,983,711UniSTSGRCm37
Celera128,373,528 - 8,373,657UniSTS
Cytogenetic Map12A1.1UniSTS
cM Map122.0UniSTS
PMC316377P5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38128,009,846 - 8,010,152UniSTSGRCm38
MGSCv37128,016,652 - 8,016,958UniSTSGRCm37
Celera128,404,691 - 8,404,997UniSTS
Cytogenetic Map12A1.1UniSTS
Apob  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38128,004,979 - 8,005,798UniSTSGRCm38
MGSCv37128,011,785 - 8,012,604UniSTSGRCm37
Celera128,399,824 - 8,400,643UniSTS
Cytogenetic Map12A1.1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301393Dyscalc3_mdystrophic cardiac calcinosis 3 (mouse)Not determined12122368579Mouse
1301143Skull17_mskull morphology 17 (mouse)Not determined12122368579Mouse
10402496Lmr22_mleishmaniasis resistance 22 (mouse)Not determined12122368579Mouse
11039525Tbbr2_mTrypanosoma brucei brucei response 2 (mouse)12122368579Mouse
1301655Bmd12_mbone mineral density 12 (mouse)Not determined12124612697Mouse
1357519Vtbt12_mvertebral trabecular bone trait 12 (mouse)Not determined12124612697Mouse
4141296Femwf9_mfemur work to failure 9 (mouse)Not determined127870733Mouse
4141112Tglq2a_mtriglyceride QTL 2a (mouse)Not determined12127870733Mouse
4141436Chldq7_mcholesterol and HDL QTL 7 (mouse)Not determined12127870733Mouse
9850128Tglq5_mtriglyceride QTL 5 (mouse)Not determined12127870733Mouse
12910983Pifs1_mpeptide-induced fatal syndrome 1 (mouse)12130383077Mouse
1301925Ath6_matherosclerosis 6 (mouse)Not determined12132708755Mouse
1301207Circp1_mcircadian photosensitivity 1 (mouse)Not determined12133380338Mouse
4141660Nbwa1_mNZB and NZW autoimmunity 1 (mouse)Not determined1229013334290301Mouse
26884410Bzwq15_mbi-zygomatic width QTL 15, 16 week (mouse)12360000029700000Mouse
4142234Tmc1m3_mTmc1 modifier 3 (mouse)Not determined12536844076984429Mouse
1301163Eae16_msusceptibility to experimental allergic encephalomyelitis 16 (mouse)Not determined12767315941673302Mouse
13208568Bmiq11_mbody mass index QTL 11 (mouse)12800000040000000Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir122mmu-miR-122-5pMirtarbaseexternal_infoWestern blotFunctional MTI16459310

Predicted Target Of
Summary Value
Count of predictions:484
Count of miRNA genes:306
Interacting mature miRNAs:342
Transcripts:ENSMUST00000037520, ENSMUST00000037811, ENSMUST00000171239, ENSMUST00000171271
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence