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Gene: Apob (apolipoprotein B) Mus musculus
Symbol: Apob
Name: apolipoprotein B
Description: Predicted to have several functions, including anion binding activity; cholesterol transfer activity; and lipase binding activity. Involved in several processes, including cholesterol efflux; lipoprotein metabolic process; and triglyceride metabolic process. Localizes to the endoplasmic reticulum. Used to study familial hypobetalipoproteinemia 2. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Is expressed in several structures, including gut; liver; metencephalon roof; placenta; and yolk sac. Orthologous to human APOB (apolipoprotein B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI315052; Apo B-100; apob-100; apob-48; apolipoprotein B-100; MGC176318
Homo sapiens (human) : APOB (apolipoprotein B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apob (apolipoprotein B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apob (apolipoprotein B)
Pan paniscus (bonobo/pygmy chimpanzee) : APOB (apolipoprotein B)
Canis lupus familiaris (dog) : APOB (apolipoprotein B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apob (apolipoprotein B)
Sus scrofa (pig) : APOB (apolipoprotein B)
Chlorocebus sabaeus (green monkey) : APOB (apolipoprotein B)
Heterocephalus glaber (naked mole-rat) : Apob (apolipoprotein B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl127,977,648 - 8,016,835 (+)Ensembl
GRCm38127,977,629 - 8,016,839 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37127,984,483 - 8,023,645 (+)NCBIGRCm37mm9NCBIm37
MGSCv36128,003,656 - 8,042,849 (+)NCBImm8
Celera128,374,429 - 8,411,685 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map123.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Apob
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735788
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.