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Gene: Apob (apolipoprotein B) Mus musculus
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Symbol: Apob
Name: apolipoprotein B
Description: Predicted to have several functions, including anion binding activity; cholesterol transfer activity; and lipase binding activity. Involved in several processes, including cholesterol efflux; lipoprotein metabolic process; and triglyceride metabolic process. Localizes to the endoplasmic reticulum. Used to study familial hypobetalipoproteinemia 2. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); biliary tract cancer (multiple); familial hyperlipidemia (multiple); hypobetalipoproteinemia (multiple); and sickle cell anemia. Is expressed in several structures, including gut; liver; metencephalon roof; placenta; and yolk sac. Orthologous to human APOB (apolipoprotein B).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AI315052; Apo B-100; apob-100; apob-48; apolipoprotein B-100; MGC176318
Orthologs:
Homo sapiens (human) : APOB (apolipoprotein B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Apob (apolipoprotein B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apob (apolipoprotein B)
Pan paniscus (bonobo/pygmy chimpanzee) : APOB (apolipoprotein B)
Canis lupus familiaris (dog) : APOB (apolipoprotein B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apob (apolipoprotein B)
Sus scrofa (pig) : APOB (apolipoprotein B)
Chlorocebus sabaeus (green monkey) : APOB (apolipoprotein B)
Heterocephalus glaber (naked mole-rat) : Apob (apolipoprotein B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl127,977,648 - 8,016,835 (+)Ensembl
GRCm38127,977,629 - 8,016,839 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37127,984,483 - 8,023,645 (+)NCBIGRCm37mm9NCBIm37
MGSCv36128,003,656 - 8,042,849 (+)NCBImm8
Celera128,374,429 - 8,411,685 (+)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map123.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Apob
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735788
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.